Ulta - Thyroid Discovery – FULL

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Reverse T3, Reverse Triiodothyronine, RT3, T3 Reverse RT3 LCMSMS, Triiodothyronine Reverse

T3 Reverse, LC/MS/MS

Reverse T3 produced in the thyroid comes from the conversion of the storage hormone T4. Your body, especially the liver, can constantly be converting T4 to RT3 as a way to get rid of any unneeded T4. In any given day approx. 40% of T4 goes to T3 and 20% of T4 goes to Reverse T3. However in any situation where your body needs to conserve energy and focus on something else, it will change the above percentages, changing the conversion of RT3 to 50% or more, and the T3 goes down, down. Examples are emotional, physical, or biological stress, such as being chronically or acutely sick (the flu, pneumonia, etc), after surgery, after a car accident or any acute injury, chronic stress causing high cortisol, being exposed to an extremely cold environment, diabetes, aging, or even being on drugs like beta blockers and amiodarone.

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Thyroglobulin Antibodies

Measurement of thyroglobulin antibodies is useful in the diagnosis and management of a variety of thyroid disorders including Hashimoto's thyroiditis, Graves Disease and certain types of goiter.

Thyroid Peroxidase

Also known as: Thyroid Stimulating Hormone, Thyroid Stimulating Hormone (TSH), Thyrotropin


A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.


*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through Quest Diagnostics. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 Quest Diagnostics laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Ulta - Thyroid Discovery – FULL panel contains 5 tests with 7 biomarkers.

Brief Description: The Ulta - Thyroid Discovery - FULL Panel is a comprehensive set of tests designed to evaluate the function and health of the thyroid gland comprehensively. This panel includes measurements of thyroid hormones, as well as antibodies that can affect thyroid health. By assessing these various components, healthcare professionals can gain insights into a patient's thyroid function, diagnose thyroid conditions, and guide treatment decisions.

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: Specifc to TSH: Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks.

According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra assay."

When and Why the Ulta - Thyroid Discovery - FULL Panel May Be Ordered

The Ulta - Thyroid Discovery - FULL Panel may be ordered when a patient presents symptoms indicative of thyroid dysfunction, such as unexpected weight changes, mood swings, changes in energy levels, or when there is a family history of thyroid disorders. It is also ordered to monitor the effectiveness of ongoing thyroid treatment. This panel provides a detailed view of the thyroid's status, helping to diagnose conditions accurately and tailor treatments effectively.

What the Ulta - Thyroid Discovery - FULL Panel Checks For

T3 Reverse

Reverse T3 (rT3) is produced when the body converts too much T4 into rT3 instead of T3, often during periods of stress or illness. High levels can indicate that the body is not utilizing thyroid hormones efficiently.

T3 Free

Free T3 (Triiodothyronine) is one of the two major hormones produced by the thyroid gland. It is crucial for metabolism and energy regulation. Abnormal levels can indicate hyperthyroidism or hypothyroidism.

T4 Free

Free T4 (Thyroxine) is another major thyroid hormone, converted to T3 in the body's tissues. It is essential for metabolism and growth. Altered levels can also suggest hyperthyroidism or hypothyroidism.

Thyroid Peroxidase Antibodies

TPO antibodies target the enzyme in the thyroid gland that plays a role in the production of thyroid hormones. Their presence is often associated with autoimmune thyroid disorders.

Thyroglobulin Antibodies

TG antibodies target thyroglobulin, the storage form of thyroid hormones. Like TPO antibodies, their presence can indicate autoimmune thyroid disease.

Thyroid Stimulating Hormone

TSH is produced by the pituitary gland and regulates the production of thyroid hormones. It is a key indicator of thyroid health, with abnormal levels pointing to hyperthyroidism or hypothyroidism.

Conditions or Diseases Detected by the Ulta - Thyroid Discovery - FULL Panel

The Ulta - Thyroid Discovery - FULL Panel can detect several thyroid-related conditions, offering a comprehensive overview that aids in accurate diagnosis and treatment planning.


Hypothyroidism is characterized by an underactive thyroid, leading to low levels of thyroid hormones. Symptoms include fatigue, weight gain, and cold intolerance. High TSH levels combined with low free T4 and T3 levels typically indicate hypothyroidism.


Hyperthyroidism results from an overactive thyroid, producing too much hormone. Symptoms include weight loss, anxiety, and heart palpitations. Low TSH levels with high free T4 and T3 levels usually suggest hyperthyroidism.

Hashimoto's Thyroiditis

An autoimmune disorder where the immune system attacks the thyroid gland, leading to reduced hormone production. High TPO and TG antibody levels, along with altered TSH, free T4, and T3 levels, can indicate Hashimoto's thyroiditis.

Graves' Disease

Another autoimmune disorder, but in this case, it leads to an overactive thyroid (hyperthyroidism). High levels of TPO or TG antibodies, along with low TSH and high free T4 and T3, are indicative of Graves' disease.

Using the Results in Treatment and Monitoring


In treating hypothyroidism, thyroid hormone replacement therapy is common. Regular monitoring of TSH and free T4 levels helps adjust medication dosage to maintain hormone levels within a target range.


Treatment may include medication, radioactive iodine, or surgery, depending on the severity. Monitoring involves assessing TSH, free T3, and T4 levels to ensure effective treatment and prevent complications.

Hashimoto's Thyroiditis

Management often focuses on symptom relief and hormone level normalization through thyroid hormone replacement. Regular monitoring of TSH, free T4, and antibody levels guides treatment adjustments.

Graves' Disease

Treatment options include anti-thyroid medications, radioactive iodine therapy, or surgery. Monitoring TSH, free T4, and T3 levels, along with antibody titers, is critical to managing the disease effectively.

The Ulta - Thyroid Discovery - FULL Panel is a vital diagnostic tool for evaluating thyroid function and guiding the treatment of thyroid-related conditions. By providing a detailed overview of hormone levels and the presence of antibodies, it enables healthcare professionals to diagnose conditions accurately, tailor treatments to individual needs, and monitor response to therapy. This comprehensive approach ensures the best possible outcomes for patients with thyroid disorders.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

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