Thyroid & Metabolism - Advanced Lab Panel

The Thyroid & Metabolism Advanced Lab Panel includes 32 tests and 127 biomarkers to support deeper review of thyroid function, thyroid conversion, thyroid antibodies, insulin resistance, blood sugar, cardiometabolic risk, inflammation, liver and kidney health, urine health, iron status, nutrients, methylation, stress hormones, and metabolism. Includes TSH, Free T4, Free T3, Reverse T3, thyroid antibodies, A1c, insulin, ApoB, Lp(a), B12, MMA, and more.

Urine, Serum, Blood, Random, Plasma-Unspecified Vial Pour
Phlebotomist
Thyroid Advanced Panel, Thyroid Metabolism Panel, Advanced Thyroid Blood Test, Thyroid Hormone Panel, Thyroid Antibody Panel, Metabolism Blood Test, Thyroid and Weight Panel, Thyroid Energy Panel

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Microalbumin Random Urine with Creatinine

Creatinine, Random Urine

Microalbumin

Microalbumin/Creatinine

Apolipoprotein B

Also known as: Bilirubin Fractionated

Bilirubin, Direct

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bilirubin, Indirect

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Also known as: C-Terminal Insulin, Connecting peptide insulin, CPeptide, Insulin C-peptide, Proinsulin C-peptide

C-Peptide

Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)

NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.

Absolute Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Absolute Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Absolute Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Absolute Eosinophils

Eosinophils (eos) respond to infections caused by parasites and play a role in allergic reactions (hypersensitivities)

Absolute Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Absolute Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Absolute Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

Absolute Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Absolute Neutrophils

Neutrophils (neu) normally make up the largest number of circulating WBCs. They move into an area of damaged or infected tissue, where they engulf and destroy bacteria or sometimes fungi. Young neutrophils, recently released into circulation, are called bands.

Absolute Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Absolute Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Eosinophils

Eosinophils are specialized white blood cells produced in the bone marrow and released into the bloodstream, where they normally make up only 0–6 % of circulating leukocytes. Their cytoplasm is packed with reddish‑orange granules that contain potent enzymes (e.g., major basic protein, eosinophil cationic protein) and inflammatory mediators. When the immune system detects large, multicellular invaders—such as helminth (worm) parasites—eosinophils migrate out of the blood and surround the pathogen, releasing these granule contents to damage the parasite’s outer surface and aid its destruction. Beyond parasite defense, eosinophils act as key orchestras of the allergic response. They accumulate in tissues exposed to allergens (airways in asthma, skin in eczema, GI tract in eosinophilic esophagitis) and secrete cytokines and lipid mediators that amplify inflammation, recruit additional immune cells, and contribute to symptoms like swelling, mucus production, and itching. Because of this pro‑inflammatory role, persistently elevated eosinophil counts—termed eosinophilia—can signal allergic disorders, drug hypersensitivity, or certain autoimmune and malignant conditions. Conversely, counts drop toward zero after glucocorticoid therapy or in acute stress states, reflecting the cells’ sensitivity to hormonal and immune regulation.

Hematocrit

Hematocrit is a blood test that measures the percentage of the volume of whole blood that is made up of red blood cells. This measurement depends on the number of red blood cells and the size of red blood cells.

Hemoglobin

Serum hemoglobin is a blood test that measures the level of free hemoglobin in the liquid part of the blood (the serum). Free hemoglobin is the hemoglobin outside of the red blood cells. Most of the hemoglobin is found inside the red blood cells, not in the serum.

Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

MCH

Mean corpuscular hemoglobin (MCH) is a calculation of the average amount of oxygen-carrying hemoglobin inside a red blood cell.

MCHC

Mean corpuscular hemoglobin concentration (MCHC) is a calculation of the average percentage of hemoglobin inside a red cell.

MCV

Mean corpuscular volume (MCV) is a measurement of the average size of RBCs.

Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

MPV

Mean Platelet Volume (MPV) - When it indicates average size of platelets are small; older platelets are generally smaller than younger ones and a low MPV may mean that a condition is affecting the production of platelets by the bone marrow. When it indicates a high number of larger, younger platelets in the blood; this may be due to the bone marrow producing and releasing platelets rapidly into circulation.

Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Neutrophils

Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed.

Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Platelet Count

A platelet count is a test to measure how many platelets you have in your blood. Platelets help the blood clot. They are smaller than red or white blood cells.

Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

RDW

Red cell distribution width (RDW), which may be included in a CBC, is a calculation of the variation in the size of RBCs.

Reactive Lymphocytes (Only Reported If Detected)

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Red Blood Cell Count

An RBC count is a blood test that tells how many red blood cells (RBCs) you have. RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

White Blood Cell Count

A WBC count is a test to measure the number of white blood cells (WBCs) in the blood. WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Albumin/Globulin Ratio

The ratio of albumin to globulin (A/G ratio) is calculated from measured albumin and calculated globulin (total protein - albumin). Normally, there is a little more albumin than globulins, giving a normal A/G ratio of slightly over 1. Because disease states affect the relative amounts of albumin and globulin, the A/G ratio may provide a clue as to the cause of the change in protein levels. A low A/G ratio may reflect overproduction of globulins, such as seen in multiple myeloma or autoimmune diseases, or underproduction of albumin, such as may occur with cirrhosis, or selective loss of albumin from the circulation, as may occur with kidney disease (nephrotic syndrome). A high A/G ratio suggests underproduction of immunoglobulins as may be seen in some genetic deficiencies and in some leukemias. More specific tests, such as liver enzyme tests and serum protein electrophoresis, must be performed to make an accurate diagnosis. With a low total protein that is due to plasma expansion (dilution of the blood), the A/G ratio will typically be normal because both albumin and globulin will be diluted to the same extent.

Alkaline Phosphatase

Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone.

Alt

Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.

AST

AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bun/Creatinine Ratio

A ratio between a person’s BUN and blood creatinine to help determine what is causing these concentrations to be higher than normal. The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration. It may also be seen with increased protein, from gastrointestinal bleeding, or increased protein in the diet. The ratio may be decreased with liver disease (due to decrease in the formation of urea) and malnutrition.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.

Carbon Dioxide

CO2 is carbon dioxide. Measures the amount of carbon dioxide in the liquid part of your blood, called the serum. In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.

Chloride

Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance. This is a measure of the amount of chloride in the fluid portion (serum) of the blood.

Creatinine

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys work.

Egfr African American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

Egfr Non-Afr. American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

GFR-AFRICAN AMERICAN

GFR-NON AFRICAN AMERICAN

Globulin

Globulins is the collective term for most blood proteins other than albumin. Identifying the types of globulins can help diagnose certain disorders. Globulins are roughly divided into three groups: alpha, beta, and gamma globulins. Gamma globulines include various types of antibodies such as immunoglobulins (Ig) M, G, and A.

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Potassium

Potassium is a mineral that the body needs to work normally. It helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Protein, Total

The total protein is the total amount of two classes of proteins, albumin and globulin that are found in the fluid portion of your blood. Proteins are important parts of all cells and tissues. Your albumin helps prevent fluid from leaking out of blood vessels and your globulins are an important part of your immune system.

Sodium

Sodium is a substance that the body needs to work properly it is vital to normal body processes, including nerve and muscle function

Urea Nitrogen (Bun)

BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down. BUN measures the amount of urea nitrogen in the blood.

Also known as: Cortisol AM

Cortisol, A.M.

A cortisol level is a blood test that measures the amount of cortisol, a steroid hormone produced by the adrenal gland. The test is done to check for increased or decreased cortisol production. Cortisol is a steroid hormone released from the adrenal gland in response to ACTH, a hormone from the pituitary gland in the brain. Cortisol affects many different body systems. It plays a role in: bone, circulatory system, immune system. metabolism of fats, carbohydrates, and protein. ervous system and stress responses.

CYSTATIN C

eGFR

Also known as: Dehydroepiandrosterone Sulfate, DHEA SO4, DHEA Sulfate Immunoassay, DHEAS, Transdehydroandrosterone

DHEA SULFATE

DHEA-sulfate test measures the amount of DHEA-sulfate in the blood. DHEA-sulfate is a weak male hormone (androgen) produced by the adrenal gland in both men and women.

Ferritin

Ferritin is a protein found inside cells that stores iron so your body can use it later. A ferritin test indirectly measures the amount of iron in your blood. The amount of ferritin in your blood (serum ferritin level) is directly related to the amount of iron stored in your body.

Also known as: Gamma Glutamyl Transferase GGT, Gamma-Glutamyl Transferase, Gamma-Glutamyl Transpeptidase, Gamma-GT, GGTP, GTP

Ggt

Gamma-glutamyl transpeptidase (GGT) is a test to measure the amount of the enzyme GGT in the blood.

Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c

HEMOGLOBIN A1C

The A1c test evaluates the average amount of glucose in the blood over the last 2 to 3 months. It does this by measuring the concentration of glycated (also often called glycosylated) hemoglobin A1c. Hemoglobin is an oxygen-transporting protein found inside red blood cells (RBCs). There are several types of normal hemoglobin, but the predominant form – about 95-98% – is hemoglobin A. As glucose circulates in the blood, some of it spontaneously binds to hemoglobin A. The hemoglobin molecules with attached glucose are called glycated hemoglobin. The higher the concentration of glucose in the blood, the more glycated hemoglobin is formed. Once the glucose binds to the hemoglobin, it remains there for the life of the red blood cell – normally about 120 days. The predominant form of glycated hemoglobin is referred to as HbA1c or A1c. A1c is produced on a daily basis and slowly cleared from the blood as older RBCs die and younger RBCs (with non-glycated hemoglobin) take their place. This test is used to monitor treatment in someone who has been diagnosed with diabetes. It helps to evaluate how well their glucose levels have been controlled by treatment over time. This test may be used to screen for and diagnose diabetes or risk of developing diabetes. In 2010, clinical practice guidelines from the American Diabetes Association (ADA) stated that A1c may be added to fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) as an option for diabetes screening and diagnosis. For monitoring purposes, an A1c of less than 7% indicates good glucose control and a lower risk of diabetic complications for the majority of diabetics. However, in 2012, the ADA and the European Association for the Study of Diabetes (EASD) issued a position statement recommending that the management of glucose control in type 2 diabetes be more "patient-centered." Data from recent studies have shown that low blood sugar (hypoglycemia) can cause complications and that people with risk of severe hypoglycemia, underlying health conditions, complications, and a limited life expectancy do not necessarily benefit from having a stringent goal of less than 7% for their A1c. The statement recommends that people work closely with their doctor to select a goal that reflects each person's individual health status and that balances risks and benefits.

Also known as: Homocysteine, Homocysteine Cardiovascular

HOMOCYSTEINE,

Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP

Hs Crp

A high-sensitivity CRP (hs-CRP) test may be used by itself, in combination with other cardiac risk markers, or in combination with a lipoprotein-associated phospholipase A2 (Lp-PLA2) test that evaluates vascular inflammation. The hs-CRP test accurately detects low concentrations of C-reactive protein to help predict a healthy person's risk of cardiovascular disease (CVD). High-sensitivity CRP is promoted by some as a test for determining a person's risk level for CVD, heart attacks, and strokes. The current thinking is that hs-CRP can play a role in the evaluation process before a person develops one of these health problems.

Also known as: Insulin (fasting)

Insulin

Insulin is a hormone that is produced and stored in the beta cells of the pancreas. It is vital for the transportation and storage of glucose at the cellular level, helps regulate blood glucose levels, and has a role in lipid metabolism. When blood glucose levels rise after a meal, insulin is released to allow glucose to move into tissue cells, especially muscle and adipose (fat) cells, where is it is used for energy production. Insulin then prompts the liver to either store the remaining excess blood glucose as glycogen for short-term energy storage and/or to use it to produce fatty acids. The fatty acids are eventually used by adipose tissue to synthesize triglycerides to form the basis of a longer term, more concentrated form of energy storage. Without insulin, glucose cannot reach most of the body's cells. Without glucose, the cells starve and blood glucose levels rise to unhealthy levels. This can cause disturbances in normal metabolic processes that result in various disorders, including kidney disease, cardiovascular disease, and vision and neurological problems. Thus, diabetes, a disorder associated with decreased insulin effects, is eventually a life-threatening condition.

Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC

% Saturation

Iron Binding Capacity

Total iron binding capacity (TIBC) is a blood test to see if you may have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.

Iron, Total

Iron is a mineral that our bodies need for many functions. For example, iron is part of hemoglobin, a protein which carries oxygen from our lungs throughout our bodies. It helps our muscles store and use oxygen. Iron is also part of many other proteins and enzymes. Your body needs the right amount of iron. If you have too little iron, you may develop iron deficiency anemia. Causes of low iron levels include blood loss, poor diet, or an inability to absorb enough iron from foods. People at higher risk of having too little iron are young children and women who are pregnant or have periods.

Also known as: Lipid Panel with Ratios (fasting), Lipid Profile with Ratios (fasting), Lipids

Chol/HDLC Ratio

Cholesterol, Total

Cholesterol is a waxy, fat-like substance that occurs naturally in all parts of the body. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can combine with other substances in the blood and stick to the walls of your arteries. This is called plaque. Plaque can narrow your arteries or even block them. High levels of cholesterol in the blood can increase your risk of heart disease. Your cholesterol levels tend to rise as you get older. There are usually no signs or symptoms that you have high blood cholesterol, but it can be detected with a blood test. You are likely to have high cholesterol if members of your family have it, if you are overweight or if you eat a lot of fatty foods. You can lower your cholesterol by exercising more and eating more fruits and vegetables. You also may need to take medicine to lower your cholesterol.

HDL Cholesterol

LDL-Cholesterol

LDL/HDL Ratio

Non HDL Cholesterol

Triglycerides

Triglycerides are a form of fat and a major source of energy for the body. This test measures the amount of triglycerides in the blood. Most triglycerides are found in fat (adipose) tissue, but some triglycerides circulate in the blood to provide fuel for muscles to work. After a person eats, an increased level of triglycerides is found in the blood as the body converts the energy not needed right away into fat. Triglycerides move via the blood from the gut to adipose tissue for storage. In between meals, triglycerides are released from fat tissue to be used as an energy source for the body. Most triglycerides are carried in the blood by lipoproteins called very low density lipoproteins (VLDL). High levels of triglycerides in the blood are associated with an increased risk of developing cardiovascular disease (CVD), although the reason for this is not well understood. Certain factors can contribute to high triglyceride levels and to risk of CVD, including lack of exercise, being overweight, smoking cigarettes, consuming excess alcohol, and medical conditions such as diabetes and kidney disease.

Also known as: Lipoprotein A, Lp (a), Lp(a)

Lipoprotein (A)

Lipoprotein-a, or Lp(a) are molecules made of proteins and fat. They carry cholesterol and similar substances through the blood. A high level of Lp(a) is considered a risk factor for heart disease. High levels of lipoproteins can increase the risk of heart disease. The test is done to check your risk of atherosclerosis, stroke, and heart attack.

Magnesium

Methylmalonic Acid

Vitamin D, 25-Oh, D2

Vitamin D2 ((ergocalciferol,) is found in fortified foods and in most vitamin preparations and supplements. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D2 is effective when it is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, D3

Vitamin D3 (cholecalcifero) which comes from animals. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D3 are is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Selenium

Also known as: Reverse T3, Reverse Triiodothyronine, RT3, T3 Reverse RT3 LCMSMS, Triiodothyronine Reverse

T3 Reverse, LC/MS/MS

Reverse T3 produced in the thyroid comes from the conversion of the storage hormone T4. Your body, especially the liver, can constantly be converting T4 to RT3 as a way to get rid of any unneeded T4. In any given day approx. 40% of T4 goes to T3 and 20% of T4 goes to Reverse T3. However in any situation where your body needs to conserve energy and focus on something else, it will change the above percentages, changing the conversion of RT3 to 50% or more, and the T3 goes down, down. Examples are emotional, physical, or biological stress, such as being chronically or acutely sick (the flu, pneumonia, etc), after surgery, after a car accident or any acute injury, chronic stress causing high cortisol, being exposed to an extremely cold environment, diabetes, aging, or even being on drugs like beta blockers and amiodarone.

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Thyroglobulin Antibodies

Measurement of thyroglobulin antibodies is useful in the diagnosis and management of a variety of thyroid disorders including Hashimoto's thyroiditis, Graves Disease and certain types of goiter.

Thyroid Peroxidase

Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

Also known as: Serum Urate, UA

Uric Acid

Uric acid is a chemical created when the body breaks down substances called purines. Purines are found in some foods and drinks. These include liver, anchovies, mackerel, dried beans and peas, and beer. Most uric acid dissolves in blood and travels to the kidneys. From there, it passes out in urine. If your body produces too much uric acid or doesn't remove enough if it, you can get sick. A high level of uric acid in the blood is called hyperuricemia.

Also known as: UA, Complete, Urinalysis UA Complete, Urine Analysis, Complete

Amorphous Sediment (Only Reported If Detected)

Appearance

Bacteria

Bacteria are living things that have only one cell. Most bacteria won't hurt you - less than 1 percent of the different types make people sick. Many are helpful. Some bacteria help to digest food, destroy disease-causing cells, and give the body needed vitamins. But infectious bacteria can make you ill. They reproduce quickly in your body. Many give off chemicals called toxins, which can damage tissue and make you sick. Examples of bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli.

Bilirubin

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Calcium Oxalate Crystals (Only Reported If Detected)

Calcium oxalate is a chemical compound that forms envelope-shaped crystals. A major constituent of human kidney stones.

Casts (Only Reported If Detected)

Urinary casts are cylindrical structures produced by the kidney and present in the urine in certain disease states. They form in the distal convoluted tubule and collecting ducts of nephrons, then dislodge and pass into the urine, where they can be detected by microscopy.

Color

Crystals (Only Reported If Detected)

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Granular Cast (Only Reported If Detected)

The second-most common type of cast, granular casts can result either from the breakdown of cellular casts or the inclusion of aggregates of plasma proteins (e.g., albumin) or immunoglobulin light chains. Depending on the size of inclusions, they can be classified as fine or coarse, though the distinction has no diagnostic significance. Their appearance is generally more cigar-shaped and of a higher refractive index than hyaline casts. While most often indicative of chronic renal disease, these casts, as with hyaline casts, can also be seen for a short time following strenuous exercise

Hyaline Cast

Urinary casts are tiny tube-shaped particles. Urinary casts may be made up of white blood cells, red blood cells, kidney cells, or substances such as protein or fat. The most common type of cast, hyaline casts are solidified Tamm-Horsfall mucoprotein secreted from the tubular epithelial cells of individual nephrons. Low urine flow, concentrated urine, or an acidic environment can contribute to the formation of hyaline casts, and, as such, they may be seen in normal individuals in dehydration or vigorous exercise. Hyaline casts are cylindrical and clear, with a low refractive index,

Ketones

Ketones are substances produced in the liver when fat cells break down in the blood. A serum ketone test is a measurement of how many ketones are in the blood.

Leukocyte Esterase

Leukocyte esterase is a urine test to look for white blood cells and other signs associated with infection.

Nitrite

Occult Blood

The test looks for hidden (occult) blood in a specimen sample. It can find blood even if you cannot see it yourself.

Ph

Level of acid

Protein

Body fluids contain many different proteins that serve diverse functions such as transport of nutrients, removal of toxins, control of metabolic processes, and defense against invaders. Protein electrophoresis is a method for separating these proteins based on their size and electrical charge. When body fluids are separated by electrophoresis, they form a characteristic pattern of bands of different widths and intensities, reflecting the mixture of proteins present. This pattern is divided into five fractions, called albumin, alpha 1, alpha 2, beta, and gamma. In some cases, the beta fraction is further divided into beta 1 and beta 2. Albumin, which is produced in the liver, accounts for about 60% of the protein in the blood. "Globulins" is a collective term used to refer to proteins other than albumin. With the exception of the immunoglobulins and some complement proteins, most of the globulins are also produced in the liver. Immunofixation electrophoresis (IFE) is a method used to identify abnormal bands seen on serum, urine, or CSF protein electrophoresis, as to which type of antibody (immunoglobulin) is present.

Rbc

RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

Reducing Substances (Only Reported If Detected)

Renal Epithelial Cells (Only Reported If Detected)

Specific Gravity

Squamous Epithelial Cells

Transitional Epithelial (Only Reported If Detected)

Triple Phosphate Crystals (Only Reported If Detected)

Struvite stones (triple phosphate/magnesium ammonium phosphate) - about 10–15% of urinary calculi are composed of struvite (ammonium magnesium phosphate, NH4MgPO4·6H2O).[44] Struvite stones (also known as "infection stones", urease or triple-phosphate stones), form most often in the presence of infection by urea-splitting bacteria

Uric Acid Crystals (Only Reported If Detected)

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

WBC

WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

YEAST (Only Reported If Detected)

Candida is the scientific name for yeast. It is a fungus that lives almost everywhere, including in your body. Usually, your immune system keeps yeast under control. If you are sick or taking antibiotics, it can multiply and cause an infection.

Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid

Folate, Serum

Folate is part of the B complex of vitamins and is measures the levels of folate in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Folate is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis.. A deficiency inr folate can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow.

Vitamin B12

Vitamin B12 is part of the B complex of vitamins and measurea the levels of vitamin B12 in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Cobalamine, or vitamin B12, is found in animal products such as red meat, fish, poultry, milk, yogurt, and eggs and is not produced in the human body. In recent years, fortified cereals, breads, and other grain products have also become important dietary sources of B12. Vitamin B12 is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis. B12 is important for nerve health. A deficiency in B12 can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow. B12 deficiency can lead to varying degrees of neuropathy, nerve damage that can cause tingling and numbness in the affected person's hands and feet.

Also known as: B6, B6 Vitamin, Pyridoxal, Pyridoxal Phosphate, Pyridoxal Phosphate (PLP), Vitamin B6 Pyridoxal Phosphate

Vitamin B6

Also known as: ZN, Plasma

Zinc

*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through a national lab. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Thyroid & Metabolism - Advanced Lab Panel panel contains 32 tests with 127 biomarkers .

Overview

The Thyroid & Metabolism - Advanced Lab Panel is designed for people who want a deeper lab-based review of biomarkers related to thyroid function, thyroid hormone conversion, thyroid autoimmunity, insulin resistance, blood sugar, cholesterol, inflammation, liver function, kidney function, urine health, nutrient status, methylation, stress hormones, and metabolic wellness.

This panel includes 32 tests and 127 biomarkers to support provider-guided conversations about fatigue, weight changes, low energy, cold intolerance, hair changes, thyroid symptoms, insulin resistance, cardiometabolic risk, liver and kidney health, nutrient cofactors, and inflammation.

This Advanced panel goes beyond an Essential thyroid screen by adding Reverse T3, thyroid antibodies, insulin, C-peptide, ApoB, Lipoprotein(a), homocysteine, methylmalonic acid, vitamin B6, iron/TIBC, selenium, zinc, GGT, bilirubin, cystatin C, urine albumin, urinalysis, cortisol, and DHEA-S.

This panel does not diagnose thyroid disease, Hashimoto’s thyroiditis, insulin resistance, diabetes, metabolic syndrome, kidney disease, liver disease, cardiovascular disease, or hormone imbalance by itself. Results should be reviewed with a licensed healthcare provider and interpreted with symptoms, age, sex, medications, supplements, thyroid medication use, diet, sleep, stress, health history, and clinical context.


Why Order This Panel?

The Thyroid & Metabolism - Advanced Lab Panel may be helpful for people who want more than basic thyroid testing and want deeper insight into the systems that may influence energy, weight, metabolism, cholesterol, blood sugar, inflammation, and overall wellness.

This panel may help provide insight into:

  • TSH, Free T4, Free T3, and Reverse T3 patterns
  • Thyroid autoimmunity with TPO and thyroglobulin antibodies
  • Blood sugar, A1c, insulin, and C-peptide patterns
  • Cholesterol, ApoB, Lipoprotein(a), and lipid ratios
  • Low-grade inflammation and homocysteine patterns
  • Liver function, bile-flow markers, and bilirubin patterns
  • Kidney filtration, urine albumin, and urinalysis findings
  • Iron storage and iron availability
  • Vitamin D, B12, folate, MMA, B6, selenium, zinc, and magnesium status
  • Cortisol and DHEA-S stress hormone patterns
  • Uric acid and metabolic stress patterns

This Panel May Be Helpful For People With

  • Fatigue or low energy
  • Weight gain or weight-loss resistance
  • Cold intolerance
  • Hair thinning or hair shedding
  • Dry skin or brittle nails
  • Brain fog or poor focus
  • Constipation or sluggish digestion
  • Thyroid symptoms with normal basic labs
  • Known thyroid antibodies or family history of thyroid disease
  • Blood sugar or insulin resistance concerns
  • High cholesterol or triglycerides
  • Inflammation concerns
  • Fatty-liver or liver enzyme concerns
  • Kidney or urine health concerns
  • Nutrient concerns related to thyroid and metabolism
  • Interest in an advanced thyroid and metabolic baseline

What This Panel Helps Evaluate

This panel helps evaluate selected biomarkers related to:

  • Thyroid function
  • Thyroid hormone availability
  • Thyroid hormone conversion
  • Autoimmune thyroid patterns
  • Blood sugar and insulin resistance
  • Cardiometabolic risk
  • Cholesterol and lipid ratios
  • Inflammation and methylation
  • Liver and bile-flow context
  • Kidney and urine health
  • Iron status
  • Vitamin D, B vitamins, selenium, zinc, and magnesium
  • Stress-response and adrenal hormone context
  • Uric acid and metabolic stress
  • General metabolic wellness

Which Tier Is Right for Me?

Essential Lab Panel

The Thyroid & Metabolism - Essential Lab Panel is best for people who want a focused thyroid and metabolic baseline. It typically reviews TSH, Free T4, Free T3, CBC, CMP, A1c, insulin, lipid panel, hs-CRP, ferritin, iron/TIBC, vitamin D, B12/folate, magnesium, and uric acid.

Choose Essential if you want an accessible first-step review of thyroid function, blood sugar, cholesterol, inflammation, iron status, key nutrients, and metabolic wellness.

Advanced Lab Panel

The Thyroid & Metabolism - Advanced Lab Panel is best for people who want deeper insight into thyroid conversion, thyroid autoimmunity, insulin production, advanced cardiovascular risk, methylation, liver/bile markers, kidney/urine markers, stress hormones, and thyroid-support nutrients.

Choose Advanced if you want additional review of Reverse T3, thyroid antibodies, C-peptide, ApoB, Lipoprotein(a), homocysteine, MMA, B6, selenium, zinc, GGT, bilirubin, cystatin C, urine albumin, urinalysis, cortisol, and DHEA-S.

Comprehensive Lab Panel

The Thyroid & Metabolism - Comprehensive Lab Panel is the broadest option. It may include premium markers for total thyroid hormones, thyroid-binding proteins, Graves’-related antibodies, iodine status, advanced lipoproteins, omega fatty acids, testosterone, and expanded thyroid-metabolic review.

Choose Comprehensive if you want the deepest review of thyroid function, thyroid conversion, thyroid autoimmunity, Graves’ antibody patterns, thyroid hormone binding, iodine, cardiometabolic risk, inflammation, nutrients, stress hormones, liver/kidney health, and metabolism.


Tests Included and Why They Matter

Core Thyroid Function, Hormone Availability & Conversion

TSH

TSH is a key thyroid screening marker.

This test is included because TSH helps evaluate how strongly the brain is signaling the thyroid gland. It is often reviewed when symptoms such as fatigue, weight changes, cold intolerance, hair shedding, constipation, brain fog, or mood changes are present.

T4, Free

Free T4 measures the available form of thyroxine, a major thyroid hormone.

This test is included because Free T4 provides thyroid hormone production and availability context beyond TSH alone. It helps support provider-guided review when symptoms and TSH do not fully explain the thyroid picture.

T3, Free

Free T3 measures the available active thyroid hormone.

This test is included because T3 is closely related to metabolism, energy output, body temperature, and thyroid hormone activity. Free T3 may provide additional context when fatigue, low energy, sluggish metabolism, or weight concerns are part of the review.

T3 Reverse, RT3, LC/MS/MS

Reverse T3 is an inactive thyroid hormone metabolite.

This test is included as an advanced thyroid conversion marker. It may provide context for thyroid hormone conversion patterns, stress physiology, illness, calorie restriction, overtraining, or other conditions that may affect thyroid hormone metabolism.


Thyroid Autoimmunity Context

Thyroid Peroxidase and Thyroglobulin Antibodies

These antibodies help evaluate autoimmune thyroid patterns.

This test is included because autoimmune thyroid activity may contribute to thyroid dysfunction and symptoms such as fatigue, weight changes, hair shedding, cold intolerance, mood changes, and brain fog. These markers may support provider-guided review of Hashimoto’s-type thyroid autoimmunity or other autoimmune thyroid patterns.


Blood Sugar, Insulin Resistance & Metabolic Function

Hemoglobin A1c

Hemoglobin A1c reflects average blood sugar over approximately the past two to three months.

This test is included because blood sugar regulation is a major part of metabolic health. A1c may provide context for prediabetes risk, diabetes risk, energy crashes, weight changes, and insulin resistance patterns.

Insulin

Insulin helps move glucose from the bloodstream into cells.

This test is included because fasting insulin may provide early insight into insulin resistance. It may be useful when symptoms include weight gain, belly fat, cravings, fatigue, or energy crashes after meals.

C-Peptide

C-peptide is released when the body makes insulin.

This test is included because it adds insulin-production and beta-cell activity context. When reviewed with insulin, glucose, and A1c, C-peptide can help support a more complete metabolic health discussion.

Comprehensive Metabolic Panel, CMP

The CMP includes glucose, liver enzymes, kidney markers, electrolytes, calcium, albumin, total protein, and other metabolic markers.

This test is included because it provides broad organ-function context for thyroid and metabolic review. CMP helps evaluate glucose, liver function, kidney function, hydration, electrolytes, calcium, albumin, and protein status.

Uric Acid

Uric acid is a metabolic waste product.

This test is included because uric acid may provide context for metabolic syndrome, insulin resistance, gout risk, kidney stone risk, blood pressure, kidney function, and cardiometabolic stress.


Cholesterol, Lipoproteins & Cardiometabolic Risk

Lipid Panel with Ratios

The Lipid Panel with Ratios evaluates total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, and cholesterol ratios.

This test is included because thyroid function can influence cholesterol and triglyceride patterns. Lipids also provide core cardiometabolic context when weight, insulin resistance, and metabolic wellness are being reviewed.

Apolipoprotein B

ApoB reflects the number of atherogenic cholesterol-carrying particles.

This test is included because ApoB may provide deeper cardiometabolic risk context than LDL cholesterol alone, especially when insulin resistance, high triglycerides, metabolic syndrome, or thyroid-related lipid changes are part of the review.

Lipoprotein(a)

Lipoprotein(a), or Lp(a), is a largely inherited cholesterol-related marker.

This test is included because Lp(a) may provide cardiovascular risk context that is not captured by a standard lipid panel. It is often useful as a baseline inherited risk marker.


Inflammation, Methylation & Vascular Context

hs-CRP

High-sensitivity C-reactive protein is a marker of low-grade inflammation.

This test is included because inflammation may overlap with metabolic syndrome, insulin resistance, thyroid symptoms, cardiometabolic risk, fatigue, and general wellness.

Homocysteine

Homocysteine is influenced by vitamin B12, folate, vitamin B6, methylation pathways, kidney function, and vascular health.

This test is included because it provides B-vitamin, methylation, vascular, cognitive, and metabolic context. It is especially useful because this panel includes B12/folate, MMA, and vitamin B6.


Liver, Bile Flow & Iron Status

Gamma Glutamyl Transferase, GGT

GGT is a liver and bile duct enzyme.

This test is included because GGT may provide liver stress, bile-flow, fatty-liver, alcohol, medication, supplement, and metabolic liver context.

Bilirubin, Fractionated

Bilirubin, Fractionated measures total, direct, and indirect bilirubin.

This test is included because bilirubin patterns provide liver processing and bile-flow context beyond standard liver enzymes.

Ferritin

Ferritin measures stored iron.

This test is included because ferritin may provide context for iron storage, inflammation, fatigue, hair shedding, metabolic liver patterns, and thyroid-symptom overlap. Ferritin should be interpreted with iron/TIBC and inflammation markers.

Iron and Total Iron Binding Capacity, TIBC

Iron and TIBC help evaluate circulating iron and iron transport capacity.

This test is included because iron availability and iron imbalance can provide context for fatigue, hair shedding, low stamina, anemia-related symptoms, inflammation, and ferritin interpretation.


Kidney, Urine & Vascular Risk

Cystatin C with eGFR

Cystatin C with eGFR provides kidney filtration context beyond creatinine alone.

This test is included because kidney function is important when evaluating metabolism, medication safety, blood pressure, cardiovascular risk, and thyroid-related wellness patterns.

Albumin, Random Urine with Creatinine

This urine test evaluates albumin relative to creatinine.

It is included because urine albumin may provide kidney and vascular risk context, especially when insulin resistance, blood pressure, diabetes risk, or cardiometabolic concerns are present.

Urinalysis, UA, Complete

A complete urinalysis evaluates urine markers such as glucose, ketones, protein, blood, specific gravity, pH, and other findings.

This test is included because urine findings may provide context for glucose handling, hydration, kidney health, protein, blood, ketones, and general urine health.


B Vitamins, Methylation & Nutrient Support

Vitamin B12 and Folate Panel, Serum

This panel measures vitamin B12 and folate.

B12 and folate support red blood cell production, nerve function, DNA synthesis, methylation, cognition, and energy. These markers are useful when fatigue, brain fog, numbness, tingling, restricted diets, or metformin use are part of the discussion.

Methylmalonic Acid

Methylmalonic acid, or MMA, is a functional marker related to vitamin B12 status.

This test is included because MMA can provide deeper B12 interpretation when serum B12 is borderline or symptoms suggest B12-related concerns.

Vitamin B6, Pyridoxal Phosphate

Vitamin B6 supports methylation, neurotransmitter pathways, amino acid metabolism, immune function, and energy metabolism.

This test is included because B6 helps interpret homocysteine and methylation patterns.

QuestAssureD™ 25-Hydroxyvitamin D, D2, D3, LC/MS/MS

Vitamin D testing measures vitamin D status.

This test is included because vitamin D supports immune, bone, muscle, mood, inflammation, and metabolic wellness. It is commonly reviewed in thyroid and metabolic health discussions.

Magnesium

Magnesium supports glucose metabolism, insulin sensitivity, muscle function, blood pressure regulation, sleep, and energy production.

This test is included because magnesium status may provide useful context for insulin resistance, metabolic health, thyroid symptoms, sleep, cramps, and energy.

Selenium

Selenium is an essential mineral involved in thyroid hormone metabolism and antioxidant pathways.

This test is included because selenium supports thyroid-related enzyme systems and antioxidant defenses. It is especially useful in this panel because thyroid antibodies and thyroid conversion markers are included.

Zinc

Zinc supports immune function, thyroid pathways, hormone pathways, wound healing, and metabolic wellness.

This test is included because zinc may provide thyroid-support and immune-health context. Zinc also supports broader metabolic and hormone wellness discussions.


Stress Hormones & Metabolic Resilience

Cortisol, A.M.

Morning cortisol provides stress-response and sleep-wake rhythm context.

This test is included because stress physiology may overlap with fatigue, cravings, belly fat, blood sugar patterns, sleep disruption, and metabolic resilience.

DHEA Sulfate, Immunoassay

DHEA-S is an adrenal androgen marker.

This test is included because DHEA-S may provide adrenal hormone, stress-response, body composition, energy, and metabolic wellness context.


Blood Health & General Wellness

CBC, includes Differential and Platelets

The CBC evaluates red blood cells, white blood cells, hemoglobin, hematocrit, platelets, and white blood cell types.

This test is included because blood health may provide context for anemia patterns, immune activity, platelet patterns, inflammation clues, infection clues, fatigue, and general wellness.


Related Biomarker Patterns This Panel May Help Identify

This panel may help identify or support provider-guided review of:

  • TSH, Free T4, Free T3, and Reverse T3 patterns
  • TPO/Tg antibody patterns
  • A1c, insulin, C-peptide, and glucose patterns
  • Lipid, ApoB, and Lp(a) patterns
  • Inflammation and homocysteine patterns
  • GGT, bilirubin, ferritin, and iron/TIBC patterns
  • Cystatin C, urine albumin, and urinalysis patterns
  • Vitamin D, B12, folate, MMA, B6, selenium, zinc, and magnesium status
  • Cortisol and DHEA-S patterns
  • Uric acid and metabolic stress patterns
  • Blood count and platelet patterns

Professional Safety and Interpretation Notice

This panel is designed to support thyroid and metabolism biomarker review. It does not diagnose thyroid disease, Hashimoto’s thyroiditis, insulin resistance, diabetes, metabolic syndrome, kidney disease, liver disease, cardiovascular disease, adrenal dysfunction, or nutrient deficiency by itself.

Results should be interpreted with a licensed healthcare provider and reviewed alongside symptoms, age, sex, medications, supplements, thyroid medication use, hormone therapy, weight history, blood pressure, family history, nutrition, physical activity, sleep, stress, and health goals.

Do not stop or change medications, thyroid medication, hormone therapy, or supplements without guidance from your healthcare provider.


How to Prepare for This Panel

Preparation may vary depending on the specific tests and lab instructions. In general:

  • Fasting may be recommended because glucose, insulin, C-peptide, and lipid markers are included.
  • Morning collection may be preferred for cortisol.
  • Bring a list of medications, supplements, thyroid medications, biotin, diabetes medications, GLP-1 medications, metformin, steroids, and doses.
  • Ask your provider whether biotin should be stopped before thyroid testing, because it may interfere with some lab assays.
  • Note symptoms such as fatigue, weight changes, cold intolerance, hair shedding, cravings, belly fat, energy crashes, and sleep disruption.
  • Drink water normally unless instructed otherwise.
  • Follow all collection instructions provided with your order.

What Happens After You Receive Your Results?

After your results are available, biomarkers can be organized into key thyroid and metabolism categories: thyroid function, thyroid conversion, thyroid autoimmunity, blood sugar, insulin resistance, cardiometabolic risk, inflammation, liver and bile flow, kidney/urine risk, methylation, nutrient status, stress hormones, and metabolic stress.

During a provider review, you can discuss whether results suggest follow-up testing, medication review, thyroid medication timing review, supplement review, nutrition changes, exercise adjustments, sleep and stress review, or additional clinical evaluation.


Additional Panels to Consider

Customers interested in the Thyroid & Metabolism - Advanced Lab Panel may also consider:

  • Thyroid & Metabolism - Essential Lab Panel
  • Thyroid & Metabolism - Comprehensive Lab Panel
  • Prediabetes & Insulin Resistance Lab Panel
  • Weight Loss Resistance & Metabolism Lab Panel
  • Fatigue, Low Energy & Brain Fog Lab Panel
  • Heart Health & Cholesterol Lab Panel
  • Women’s Hormone Balance & Perimenopause Lab Panel
  • Men’s Testosterone, Energy & Vitality Lab Panel
  • Vitamin, Mineral & Nutrient Deficiency Lab Panel
  • Longevity & Healthy Aging Lab Panel

FAQ: Thyroid & Metabolism - Advanced Lab Panel

What is the Thyroid & Metabolism Advanced Lab Panel?

The Thyroid & Metabolism Advanced Lab Panel is a blood and urine test panel that includes 32 tests and 127 biomarkers to evaluate thyroid function, thyroid conversion, thyroid antibodies, blood sugar, insulin resistance, cardiometabolic risk, inflammation, liver and kidney health, nutrients, stress hormones, and metabolism.

Does this panel diagnose thyroid disease?

No. This panel does not diagnose thyroid disease by itself. Results should be reviewed by a licensed healthcare provider using symptoms, medical history, medications, thyroid medication use, and clinical context.

What thyroid markers are included?

This panel includes TSH, Free T4, Free T3, Reverse T3, and thyroid peroxidase and thyroglobulin antibodies.

Why is Reverse T3 included?

Reverse T3 is an inactive thyroid hormone metabolite. It may provide thyroid conversion and stress-related context when reviewed with TSH, Free T4, Free T3, symptoms, medications, and provider guidance.

Why are thyroid antibodies included?

Thyroid antibodies may provide autoimmune thyroid context and may be useful when Hashimoto’s-type patterns, thyroid symptoms, or family history of thyroid disease are part of the review.

Why are insulin, C-peptide, and A1c included?

These markers help evaluate blood sugar, insulin resistance, and insulin production. Thyroid symptoms and metabolic symptoms can overlap, especially with fatigue, weight changes, cravings, and energy swings.

Why are ApoB and Lipoprotein(a) included?

ApoB and Lipoprotein(a) provide advanced cardiometabolic risk context beyond a standard lipid panel. Thyroid function can influence cholesterol and triglyceride patterns.

Why are selenium, zinc, B vitamins, vitamin D, and magnesium included?

These nutrients may support thyroid, immune, metabolic, nerve, energy, and inflammation-related pathways.

Should I choose Essential, Advanced, or Comprehensive?

Choose Essential for a focused thyroid and metabolic baseline, Advanced for deeper thyroid conversion, autoimmunity, insulin resistance, liver/kidney, nutrient, and inflammation review, and Comprehensive for the broadest thyroid-metabolism review with Graves’ antibodies, iodine, thyroid binding, advanced lipids, hormones, and omega status.


Important Note

This panel is designed to help evaluate selected biomarkers related to thyroid function, metabolism, blood sugar, insulin resistance, cardiometabolic risk, inflammation, liver health, kidney function, nutrient status, stress hormones, and urine health. It is not intended to diagnose, treat, cure, or prevent disease by itself. Results should be reviewed with a licensed healthcare provider.

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