Ulta Lab Tests

Thyroid Function, Antibodies & Graves - Comprehensive Lab Panel

The Thyroid Function, Antibodies & Graves’ Comprehensive Lab Panel includes 10 tests and 11 biomarkers to support a deep review of thyroid function, thyroid signaling, hormone production, active thyroid hormone availability, thyroid conversion, thyroid binding, autoimmune thyroid patterns, Graves’-related TSI antibodies, and iodine status. Includes TSH, Free T4, Free T3, Reverse T3, Total T3, Total T4, TBG, TPO/Tg antibodies, TSI, and iodine.

Serum
Phlebotomist
Comprehensive Thyroid Panel, Graves’ Thyroid Panel, Thyroid Antibodies Panel, Full Thyroid Blood Test, Advanced Thyroid Panel, TSI Thyroid Test Panel, Thyroid Function Panel, Thyroid Wellness Test,

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Iodine SerumPlasma, Iodine, Serum

Iodine, Serum/Plasma

Also known as: Reverse T3, Reverse Triiodothyronine, RT3, T3 Reverse RT3 LCMSMS, Triiodothyronine Reverse

T3 Reverse, LC/MS/MS

Reverse T3 produced in the thyroid comes from the conversion of the storage hormone T4. Your body, especially the liver, can constantly be converting T4 to RT3 as a way to get rid of any unneeded T4. In any given day approx. 40% of T4 goes to T3 and 20% of T4 goes to Reverse T3. However in any situation where your body needs to conserve energy and focus on something else, it will change the above percentages, changing the conversion of RT3 to 50% or more, and the T3 goes down, down. Examples are emotional, physical, or biological stress, such as being chronically or acutely sick (the flu, pneumonia, etc), after surgery, after a car accident or any acute injury, chronic stress causing high cortisol, being exposed to an extremely cold environment, diabetes, aging, or even being on drugs like beta blockers and amiodarone.

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: Triiodothyronine

T3, Total

Triiodothyronine (T3) is a thyroid hormone. It plays an important role in the body's control of metabolism.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Also known as: Thyroxine Total

Free T4 Index (T7)

FTI stands for the Free Thyroxine Index and is also sometimes referred to as T7. It is a calculated value determined from the T3 uptake test and total T4 test and provides an estimate of the level of free T4 in the blood.

T4 (Thyroxine), Total

This test measures the amount of thyroxine, or T4, in the blood. T4 is one of two major hormones produced by the thyroid gland. The total T4 test is used to help diagnose hyperthyroidism and hypothyroidism. It is a useful test but can be affected by the amount of protein available in the blood to bind to the hormone.

Also known as: TBG Thyroxine Binding Globulin, Thyroxine Binding Globulin, Thyroxine-binding globulin (TBG)

TBG

Thyroglobulin Antibodies

Measurement of thyroglobulin antibodies is useful in the diagnosis and management of a variety of thyroid disorders including Hashimoto's thyroiditis, Graves Disease and certain types of goiter.

Thyroid Peroxidase

Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

Also known as: Thyroid Receptor Antibody, Thyroid Stimulating Immunoglobulin, TSI Thyroid Stimulating Immunoglobulin

TSI

*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through a national lab. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Thyroid Function, Antibodies & Graves - Comprehensive Lab Panel panel contains 10 tests with 12 biomarkers .

Overview

The Thyroid Function, Antibodies & Graves’ - Comprehensive Lab Panel is designed for people who want the deepest thyroid-specific review without adding broader metabolic, lipid, kidney, liver, or nutrient testing.

This panel includes 10 tests and 11 biomarkers that evaluate thyroid signaling, thyroid hormone production, active thyroid hormone availability, thyroid conversion, total thyroid hormone levels, thyroid hormone binding, autoimmune thyroid antibody patterns, Graves’-related thyroid-stimulating antibody context, and iodine status.

The thyroid helps regulate metabolism, energy, temperature balance, heart rate, digestion, mood, hair and skin health, and many other body functions. Thyroid-related symptoms may include fatigue, weight changes, cold intolerance, heat intolerance, hair thinning, dry skin, constipation, brain fog, mood changes, palpitations, tremor, or changes in energy.

This panel does not diagnose hypothyroidism, hyperthyroidism, Hashimoto’s thyroiditis, Graves’ disease, iodine deficiency, pituitary disease, or autoimmune disease by itself. Results should be reviewed with a licensed healthcare provider and interpreted with symptoms, medications, supplements, thyroid medication use, iodine intake, pregnancy status, health history, family history, and clinical context.

Why Order This Panel?

The Thyroid Function, Antibodies & Graves’ - Comprehensive Lab Panel may be helpful for people who want a full thyroid-specific review that goes beyond TSH, Free T4, and Free T3.

This panel may help provide insight into:

  • Thyroid signaling with TSH
  • Thyroid hormone production with Free T4 and Total T4
  • Active thyroid hormone availability with Free T3 and Total T3
  • Thyroid conversion context with Reverse T3
  • Thyroid hormone binding with TBG
  • Autoimmune thyroid patterns with TPO and thyroglobulin antibodies
  • Graves’-related antibody context with TSI
  • Iodine status with serum/plasma iodine
  • Thyroid patterns that may overlap with fatigue, weight changes, temperature sensitivity, hair changes, mood changes, or metabolism concerns

This Panel May Be Helpful For People With

  • Fatigue or low energy
  • Weight gain or difficulty losing weight
  • Unexplained weight loss
  • Cold intolerance
  • Heat intolerance
  • Hair thinning or hair shedding
  • Dry skin
  • Brittle nails
  • Brain fog or poor focus
  • Constipation or sluggish digestion
  • Palpitations or tremor when medically appropriate to review
  • Mood changes
  • Family history of thyroid disease
  • Known thyroid antibodies
  • Suspected Hashimoto’s-type thyroid patterns
  • Suspected Graves’-related thyroid patterns
  • Interest in thyroid conversion, thyroid binding, or iodine status

Which Tier Is Right for Me?

Essential Lab Panel

The Thyroid Function - Essential Lab Panel is best for people who want a focused starting point for thyroid function testing. It typically includes TSH, Free T4, and Free T3.

Choose Essential if you want a simple thyroid function review focused on thyroid signaling, thyroid hormone production, and active thyroid hormone availability.

Advanced Lab Panel

The Thyroid Function & Antibodies - Advanced Lab Panel is best for people who want thyroid function plus thyroid conversion and autoimmune thyroid context. It may include TSH, Free T4, Free T3, Reverse T3, thyroid peroxidase antibodies, and thyroglobulin antibodies.

Choose Advanced if you have persistent thyroid-like symptoms, family history of thyroid disease, known thyroid antibodies, or interest in Hashimoto’s-type thyroid patterns.

Comprehensive Lab Panel

The Thyroid Function, Antibodies & Graves’ - Comprehensive Lab Panel is the broadest thyroid-specific option. It includes 10 tests and 11 biomarkers for thyroid function, conversion, total hormone levels, thyroid binding, autoimmune thyroid antibodies, Graves’-related TSI antibodies, and iodine status.

Choose Comprehensive if you want the deepest thyroid-only review, including TSH, Free T4, Free T3, Reverse T3, Total T3, Total T4, TBG, TPO/Tg antibodies, TSI, and iodine.

Tests Included and Why They Matter

Thyroid Signaling

TSH

TSH stands for thyroid-stimulating hormone.

TSH is included because it helps evaluate how strongly the brain is signaling the thyroid gland. When thyroid hormone patterns change, TSH may shift as the body tries to maintain balance.

This marker may provide context when symptoms include fatigue, weight changes, cold intolerance, heat intolerance, constipation, brain fog, mood changes, palpitations, or changes in energy. TSH should be interpreted with Free T4, Free T3, antibody markers, symptoms, medications, thyroid medication use, and provider guidance.

Thyroid Hormone Production and Availability

T4, Free

Free T4 measures the available form of thyroxine, a major thyroid hormone made by the thyroid gland.

Free T4 is included because it helps evaluate thyroid hormone production and availability. It provides important context beyond TSH alone and may help show whether the thyroid is producing enough available T4 hormone.

T4, Total

Total T4 measures both bound and unbound thyroxine.

Total T4 is included because it adds broader thyroid hormone production context. When reviewed with Free T4 and TBG, Total T4 may help provide insight into thyroid hormone binding patterns and total circulating thyroid hormone levels.

Active Thyroid Hormone Availability

T3, Free

Free T3 measures the available active form of triiodothyronine.

Free T3 is included because T3 is closely related to metabolism, energy output, temperature regulation, and thyroid hormone activity in tissues. It may provide useful context when fatigue, low energy, sluggish metabolism, or weight concerns are part of the review.

T3, Total

Total T3 measures both bound and unbound triiodothyronine.

Total T3 is included because it adds total active thyroid hormone context. It may be useful when reviewed with Free T3, Total T4, Free T4, TBG, TSH, symptoms, and provider guidance.

Thyroid Conversion Context

T3 Reverse, RT3, LC/MS/MS

Reverse T3 is an inactive thyroid hormone metabolite.

Reverse T3 is included because it may provide thyroid conversion context. It may be reviewed when symptoms suggest thyroid imbalance but basic thyroid markers do not fully explain the clinical picture.

Reverse T3 can be influenced by illness, stress, calorie restriction, overtraining, certain medications, and other physiologic factors. It should be interpreted carefully with TSH, Free T4, Free T3, symptoms, health history, and provider guidance.

Thyroid Binding Context

TBG, Thyroxine Binding Globulin

TBG is a protein that binds thyroid hormones in the bloodstream.

TBG is included because thyroid hormone binding can affect total thyroid hormone levels. It may be useful when total thyroid hormone results and free thyroid hormone results do not align or when medications, hormones, pregnancy, liver patterns, or binding changes are part of the provider-guided review.

Autoimmune Thyroid Context

Thyroid Peroxidase and Thyroglobulin Antibodies

This test includes two antibody biomarkers: thyroid peroxidase antibodies and thyroglobulin antibodies.

These biomarkers are included because they may provide autoimmune thyroid context. Thyroid peroxidase antibodies and thyroglobulin antibodies may be reviewed when Hashimoto’s-type thyroid patterns, family history of thyroid disease, thyroid symptoms, or unexplained thyroid changes are part of the provider-guided evaluation.

Antibody results do not diagnose a condition by themselves. They should be interpreted with TSH, Free T4, Free T3, symptoms, thyroid medication use, and provider guidance.

Graves’-Related Thyroid Antibody Context

TSI, Thyroid Stimulating Immunoglobulin

TSI is a thyroid-stimulating antibody marker.

TSI is included because it may provide Graves’-related thyroid antibody context. This marker can be useful when symptoms or thyroid results suggest thyroid stimulation, such as low TSH patterns, heat intolerance, palpitations, tremor, anxiety-like symptoms, unexplained weight loss, or increased thyroid hormone activity.

This panel includes TSI but does not include TRAb. Customers or providers who want both Graves’-related antibody markers may consider adding TRAb separately if available.

Iodine Status

Iodine, Serum/Plasma

Iodine is a trace mineral used to make thyroid hormones.

Iodine is included because iodine status may provide thyroid nutrient context. Iodine should be interpreted carefully because both too little and too much iodine may affect thyroid function. Customers should not start, stop, or change iodine supplementation based only on one lab result without provider guidance.

Related Biomarker Patterns This Panel May Help Identify

This panel may help support provider-guided review of:

  • TSH thyroid signaling patterns
  • Free T4 and Total T4 thyroid hormone production patterns
  • Free T3 and Total T3 active thyroid hormone patterns
  • Reverse T3 thyroid conversion patterns
  • TBG thyroid hormone binding patterns
  • Thyroid peroxidase antibody patterns
  • Thyroglobulin antibody patterns
  • TSI Graves’-related antibody context
  • Iodine status
  • Thyroid function patterns that may overlap with fatigue
  • Thyroid function patterns that may overlap with weight changes
  • Thyroid function patterns that may overlap with cold or heat intolerance
  • Thyroid function patterns that may overlap with hair, skin, mood, digestion, energy, or metabolism concerns

Professional Safety and Interpretation Notice

This panel is designed to support thyroid function, thyroid conversion, thyroid binding, thyroid antibody, Graves’-related TSI antibody, and iodine review. It does not diagnose thyroid disease, hypothyroidism, hyperthyroidism, Hashimoto’s thyroiditis, Graves’ disease, autoimmune disease, pituitary disease, iodine deficiency, or iodine excess by itself.

Results should be interpreted with a licensed healthcare provider and reviewed alongside symptoms, medical history, medications, supplements, thyroid medication use, iodine intake, pregnancy status, family history, and clinical context.

Do not stop or change thyroid medication, hormone therapy, prescription medication, iodine supplements, or other supplements without guidance from your healthcare provider.

How to Prepare for This Panel

Preparation may vary depending on the specific tests and lab instructions. In general:

  • Bring a list of medications, supplements, thyroid medications, hormones, iodine supplements, kelp products, multivitamins, and doses.
  • Tell your provider if you take biotin, because biotin may interfere with some thyroid lab assays.
  • Ask your healthcare provider whether timing matters if you take thyroid medication.
  • Note symptoms such as fatigue, weight changes, cold intolerance, heat intolerance, hair shedding, constipation, palpitations, tremor, mood changes, anxiety-like symptoms, or sleep changes.
  • Follow all collection instructions provided with your order.

What Happens After You Receive Your Results?

After results are available, your biomarkers can be organized into thyroid signaling, hormone production, active hormone availability, thyroid conversion, thyroid binding, autoimmune thyroid patterns, Graves’-related TSI antibody context, and iodine status.

During a provider review, you can discuss whether results suggest the need for repeat testing, TRAb testing, thyroid medication timing review, iodine intake review, nutrient review, metabolic testing, imaging, or additional clinical evaluation.

Additional Panels to Consider

Customers interested in the Thyroid Function, Antibodies & Graves’ - Comprehensive Lab Panel may also consider:

  • Thyroid Function - Essential Lab Panel
  • Thyroid Function & Antibodies - Advanced Lab Panel
  • Thyroid & Metabolism - Essential Lab Panel
  • Thyroid & Metabolism - Advanced Lab Panel
  • Thyroid & Metabolism - Comprehensive Lab Panel
  • Fatigue, Low Energy & Brain Fog Lab Panel
  • Weight Loss Resistance & Metabolism Lab Panel
  • Women’s Hormone Balance & Perimenopause Lab Panel
  • Vitamin, Mineral & Nutrient Deficiency Lab Panel

FAQ: Thyroid Function, Antibodies & Graves’ - Comprehensive Lab Panel

What is the Thyroid Function, Antibodies & Graves’ Comprehensive Lab Panel?

The Thyroid Function, Antibodies & Graves’ Comprehensive Lab Panel is a thyroid blood test panel that includes 10 tests and 11 biomarkers. It evaluates thyroid function, thyroid hormone production, active thyroid hormone availability, thyroid conversion, thyroid binding, thyroid antibodies, Graves’-related TSI antibody context, and iodine status.

What thyroid tests are included?

This panel includes TSH, Free T4, Free T3, Reverse T3, Total T3, Total T4, TBG, thyroid peroxidase antibodies, thyroglobulin antibodies, TSI, and iodine.

Does this panel diagnose Graves’ disease?

No. This panel does not diagnose Graves’ disease by itself. TSI results should be reviewed with TSH, Free T4, Free T3, symptoms, medical history, medications, and provider guidance.

Does this panel include TRAb?

No. This listed panel includes TSI but does not include TRAb. Customers or providers who want additional Graves’-related antibody context may consider adding TRAb separately if available.

Does this panel diagnose Hashimoto’s thyroiditis?

No. Thyroid peroxidase and thyroglobulin antibodies may provide autoimmune thyroid context, but diagnosis requires clinical interpretation with thyroid function results, symptoms, history, and provider guidance.

Why are Total T3, Total T4, and TBG included?

Total T3 and Total T4 provide total thyroid hormone context, while TBG helps evaluate thyroid hormone binding. This may be useful when total and free thyroid hormone results do not align.

Why is Reverse T3 included?

Reverse T3 is an inactive thyroid hormone metabolite. It may provide thyroid conversion context when reviewed with TSH, Free T4, Free T3, symptoms, medications, and health history.

Why is iodine included?

Iodine is used to make thyroid hormones. Iodine status should be interpreted carefully because both low and high iodine exposure may affect thyroid function.

Should I choose Essential, Advanced, or Comprehensive?

Choose Essential for focused thyroid function testing. Choose Advanced for thyroid function, Reverse T3, and thyroid antibodies. Choose Comprehensive for thyroid function, antibodies, Graves’-related TSI, thyroid binding, total thyroid hormone markers, and iodine context.

Important Note

This panel is designed to help evaluate selected biomarkers related to thyroid function, thyroid hormone production, thyroid signaling, active thyroid hormone availability, thyroid conversion, thyroid hormone binding, autoimmune thyroid patterns, Graves’-related antibody context, and iodine status. It is not intended to diagnose, treat, cure, or prevent disease by itself. Results should be reviewed with a licensed healthcare provider.

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