Ulta Lab Tests

Thyroid Function & Antibodies - Advanced Lab Panel

The Thyroid Function & Antibodies Advanced Lab Panel includes 5 tests and 6 biomarkers to support a deeper review of thyroid function, thyroid signaling, hormone production, active thyroid hormone availability, thyroid conversion, and autoimmune thyroid patterns. It includes TSH, Free T4, Free T3, Reverse T3, thyroid peroxidase antibodies, and thyroglobulin antibodies for provider-guided thyroid wellness review.

Serum
Phlebotomist
Advanced Thyroid Panel, Thyroid Antibodies Panel, Hashimoto’s Blood Test, Full Thyroid Panel, Reverse T3 Test Panel, Thyroid Function Panel, Thyroid Wellness Test, Thyroid Blood Test

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Reverse T3, Reverse Triiodothyronine, RT3, T3 Reverse RT3 LCMSMS, Triiodothyronine Reverse

T3 Reverse, LC/MS/MS

Reverse T3 produced in the thyroid comes from the conversion of the storage hormone T4. Your body, especially the liver, can constantly be converting T4 to RT3 as a way to get rid of any unneeded T4. In any given day approx. 40% of T4 goes to T3 and 20% of T4 goes to Reverse T3. However in any situation where your body needs to conserve energy and focus on something else, it will change the above percentages, changing the conversion of RT3 to 50% or more, and the T3 goes down, down. Examples are emotional, physical, or biological stress, such as being chronically or acutely sick (the flu, pneumonia, etc), after surgery, after a car accident or any acute injury, chronic stress causing high cortisol, being exposed to an extremely cold environment, diabetes, aging, or even being on drugs like beta blockers and amiodarone.

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Thyroglobulin Antibodies

Measurement of thyroglobulin antibodies is useful in the diagnosis and management of a variety of thyroid disorders including Hashimoto's thyroiditis, Graves Disease and certain types of goiter.

Thyroid Peroxidase

Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.
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The Thyroid Function & Antibodies - Advanced Lab Panel panel contains 5 tests with 6 biomarkers .

Overview

The Thyroid Function & Antibodies - Advanced Lab Panel is designed for people who want a deeper thyroid-specific review than a basic thyroid function panel. This panel includes 5 tests and 6 biomarkers that evaluate thyroid signaling, thyroid hormone production, active thyroid hormone availability, thyroid hormone conversion, and autoimmune thyroid antibody patterns.

The thyroid helps regulate metabolism, energy, temperature balance, heart rate, digestion, mood, hair and skin health, and many other body functions. When thyroid patterns are not balanced, symptoms may overlap with fatigue, weight changes, cold intolerance, heat intolerance, hair thinning, dry skin, constipation, brain fog, mood changes, palpitations, or changes in energy.

This Advanced panel goes beyond TSH, Free T4, and Free T3 by adding Reverse T3 and thyroid peroxidase and thyroglobulin antibodies. These additional markers may help provide context for thyroid conversion and autoimmune thyroid patterns.

This panel does not diagnose thyroid disease, Hashimoto’s thyroiditis, Graves’ disease, hypothyroidism, hyperthyroidism, or autoimmune disease by itself. Results should be reviewed with a licensed healthcare provider and interpreted with symptoms, medications, supplements, thyroid medication use, pregnancy status, medical history, family history, and clinical context.

Why Order This Panel?

The Thyroid Function & Antibodies - Advanced Lab Panel may be helpful for people who want a more complete thyroid-specific review without adding broader metabolic, lipid, kidney, liver, or nutrient testing.

This panel may help provide insight into:

  • Thyroid signaling with TSH
  • Thyroid hormone production with Free T4
  • Active thyroid hormone availability with Free T3
  • Thyroid conversion context with Reverse T3
  • Autoimmune thyroid patterns with TPO antibodies
  • Autoimmune thyroid patterns with thyroglobulin antibodies
  • Thyroid patterns that may overlap with fatigue, weight changes, temperature sensitivity, hair changes, mood changes, or metabolism concerns

This Panel May Be Helpful For People With

  • Fatigue or low energy
  • Weight gain or difficulty losing weight
  • Unexplained weight loss
  • Cold intolerance
  • Heat intolerance
  • Hair thinning or hair shedding
  • Dry skin
  • Brittle nails
  • Brain fog or poor focus
  • Constipation or sluggish digestion
  • Mood changes
  • Family history of thyroid disease
  • Known or suspected thyroid antibodies
  • Persistent thyroid-like symptoms despite basic thyroid testing
  • Interest in Hashimoto’s-type thyroid antibody context
  • Interest in thyroid conversion context

What This Panel Helps Evaluate

This panel helps evaluate selected biomarkers related to:

  • Thyroid function
  • Thyroid signaling
  • Thyroid hormone production
  • Active thyroid hormone availability
  • Thyroid hormone conversion
  • Reverse T3 patterns
  • Thyroid peroxidase antibody patterns
  • Thyroglobulin antibody patterns
  • Autoimmune thyroid context
  • Provider-guided thyroid wellness review

Which Tier Is Right for Me?

Essential Lab Panel

The Thyroid Function - Essential Lab Panel is best for people who want a focused starting point for thyroid function testing. It typically includes TSH, Free T4, and Free T3.

Choose Essential if you want a simple thyroid function review focused on thyroid signaling, thyroid hormone production, and active thyroid hormone availability.

Advanced Lab Panel

The Thyroid Function & Antibodies - Advanced Lab Panel is best for people who want thyroid function plus thyroid conversion and autoimmune thyroid context. It includes 5 tests and 6 biomarkers: TSH, Free T4, Free T3, Reverse T3, thyroid peroxidase antibodies, and thyroglobulin antibodies.

Choose Advanced if you have persistent thyroid-like symptoms, family history of thyroid disease, known thyroid antibodies, or interest in Hashimoto’s-type thyroid patterns.

Comprehensive Lab Panel

The Thyroid Function, Antibodies & Graves’ - Comprehensive Lab Panel is the broadest thyroid-specific option. It may include thyroid function markers, Reverse T3, Total T3, Total T4, TBG, thyroid antibodies, TRAb, TSI, and iodine status.

Choose Comprehensive if you want the deepest thyroid-only review, including thyroid conversion, thyroid hormone binding, autoimmune thyroid patterns, Graves’-related antibodies, and iodine context.

Tests Included and Why They Matter

Thyroid Signaling

TSH

TSH stands for thyroid-stimulating hormone.

TSH is included because it helps evaluate how strongly the brain is signaling the thyroid gland. When thyroid hormone levels are low or high, TSH may shift as the body tries to maintain balance. TSH is commonly reviewed as a first-step thyroid marker.

This biomarker may provide context when symptoms include fatigue, weight changes, cold intolerance, heat intolerance, constipation, brain fog, mood changes, or changes in heart rate. TSH should be interpreted with Free T4, Free T3, symptoms, medications, thyroid medication use, and provider guidance.

Thyroid Hormone Production

T4, Free

Free T4 measures the available form of thyroxine, a major thyroid hormone made by the thyroid gland.

Free T4 is included because it helps evaluate thyroid hormone production and availability. It provides important context beyond TSH alone and may help show whether the thyroid is producing enough available T4 hormone.

Free T4 may be useful when symptoms suggest thyroid imbalance or when TSH results do not fully explain how a person feels. It should be interpreted with TSH, Free T3, Reverse T3, symptoms, medications, thyroid medication use, and provider guidance.

Active Thyroid Hormone Availability

T3, Free

Free T3 measures the available active form of triiodothyronine.

Free T3 is included because T3 is closely related to metabolism, energy output, temperature regulation, and thyroid hormone activity in tissues. Some T4 is converted into T3, so Free T3 may provide useful context about active thyroid hormone availability.

Free T3 may be helpful when reviewing fatigue, low energy, sluggish metabolism, weight concerns, temperature sensitivity, or thyroid medication response. It should be interpreted with TSH, Free T4, Reverse T3, symptoms, medications, and provider guidance.

Thyroid Conversion Context

T3 Reverse, RT3, LC/MS/MS

Reverse T3 is an inactive thyroid hormone metabolite.

Reverse T3 is included because it may provide thyroid conversion context. It may be reviewed when symptoms suggest thyroid imbalance but basic thyroid markers do not fully explain the clinical picture.

Reverse T3 can be influenced by illness, stress, calorie restriction, overtraining, certain medications, and other physiologic factors. It should be interpreted carefully with TSH, Free T4, Free T3, symptoms, health history, and provider guidance.

Autoimmune Thyroid Context

Thyroid Peroxidase and Thyroglobulin Antibodies

This test includes two thyroid antibody biomarkers: thyroid peroxidase antibodies and thyroglobulin antibodies.

These biomarkers are included because they may provide autoimmune thyroid context. Thyroid peroxidase antibodies and thyroglobulin antibodies may be reviewed when Hashimoto’s-type thyroid patterns, family history of thyroid disease, thyroid symptoms, or unexplained thyroid changes are part of the provider-guided evaluation.

Antibody results do not diagnose a condition by themselves. They should be interpreted with TSH, Free T4, Free T3, symptoms, thyroid medication use, and provider guidance.

Related Biomarker Patterns This Panel May Help Identify

This panel may help support provider-guided review of:

  • TSH thyroid signaling patterns
  • Free T4 thyroid hormone production patterns
  • Free T3 active thyroid hormone availability patterns
  • Reverse T3 thyroid conversion patterns
  • Thyroid peroxidase antibody patterns
  • Thyroglobulin antibody patterns
  • Autoimmune thyroid context
  • Thyroid function patterns that may overlap with fatigue
  • Thyroid function patterns that may overlap with weight changes
  • Thyroid function patterns that may overlap with cold or heat intolerance
  • Thyroid function patterns that may overlap with hair, skin, mood, digestion, energy, or metabolism concerns

Professional Safety and Interpretation Notice

This panel is designed to support thyroid function, thyroid conversion, and thyroid antibody review. It does not diagnose thyroid disease, hypothyroidism, hyperthyroidism, Hashimoto’s thyroiditis, Graves’ disease, autoimmune disease, pituitary disease, or any medical condition by itself.

Results should be interpreted with a licensed healthcare provider and reviewed alongside symptoms, medical history, medications, supplements, thyroid medication use, pregnancy status, family history, and clinical context.

Do not stop or change thyroid medication, hormone therapy, prescription medication, or supplements without guidance from your healthcare provider.

How to Prepare for This Panel

Preparation may vary depending on the specific tests and lab instructions. In general:

  • Bring a list of medications, supplements, thyroid medications, hormones, and doses.
  • Tell your provider if you take biotin, because biotin may interfere with some thyroid lab assays.
  • Note symptoms such as fatigue, weight changes, cold intolerance, heat intolerance, hair shedding, mood changes, constipation, palpitations, tremor, or sleep changes.
  • Follow all collection instructions provided with your order.
  • Ask your healthcare provider whether timing matters if you take thyroid medication.

What Happens After You Receive Your Results?

After results are available, your biomarkers can be organized into thyroid signaling, thyroid hormone production, active thyroid hormone availability, thyroid conversion, and thyroid antibody patterns.

During a provider review, you can discuss whether results suggest the need for repeat testing, Graves’-related antibody testing, iodine review, thyroid medication timing review, nutrient review, metabolic testing, or further clinical evaluation.

Additional Panels to Consider

Customers interested in the Thyroid Function & Antibodies - Advanced Lab Panel may also consider:

  • Thyroid Function - Essential Lab Panel
  • Thyroid Function, Antibodies & Graves’ - Comprehensive Lab Panel
  • Thyroid & Metabolism - Essential Lab Panel
  • Thyroid & Metabolism - Advanced Lab Panel
  • Thyroid & Metabolism - Comprehensive Lab Panel
  • Fatigue, Low Energy & Brain Fog Lab Panel
  • Weight Loss Resistance & Metabolism Lab Panel
  • Women’s Hormone Balance & Perimenopause Lab Panel
  • Vitamin, Mineral & Nutrient Deficiency Lab Panel

FAQ: Thyroid Function & Antibodies - Advanced Lab Panel

What is the Thyroid Function & Antibodies Advanced Lab Panel?

The Thyroid Function & Antibodies Advanced Lab Panel is a thyroid blood test panel that includes 5 tests and 6 biomarkers: TSH, Free T4, Free T3, Reverse T3, thyroid peroxidase antibodies, and thyroglobulin antibodies. It supports provider-guided review of thyroid function, thyroid conversion, and autoimmune thyroid patterns.

What thyroid tests are included?

This panel includes TSH, Free T4, Free T3, Reverse T3, thyroid peroxidase antibodies, and thyroglobulin antibodies.

Does this panel diagnose Hashimoto’s thyroiditis?

No. This panel does not diagnose Hashimoto’s thyroiditis by itself. Thyroid antibody results should be reviewed with thyroid hormone results, symptoms, medical history, and provider guidance.

Why are thyroid antibodies included?

Thyroid antibodies may provide autoimmune thyroid context. They may be useful when there is a family history of thyroid disease, persistent thyroid-like symptoms, known thyroid antibodies, or suspected Hashimoto’s-type thyroid patterns.

Why is Reverse T3 included?

Reverse T3 is an inactive thyroid hormone metabolite. It may provide thyroid conversion context when reviewed with TSH, Free T4, Free T3, symptoms, medications, and health history.

Does this panel include Graves’ disease antibody markers?

No. This Advanced panel does not include TRAb or TSI. Customers who want Graves’-related antibody context may consider the Thyroid Function, Antibodies & Graves’ - Comprehensive Lab Panel.

Does this panel include iodine?

No. Iodine is not included in this Advanced panel. Customers who want iodine status reviewed may consider the Comprehensive thyroid panel.

Should I choose Essential, Advanced, or Comprehensive?

Choose Essential for a focused thyroid function review. Choose Advanced for thyroid function, Reverse T3, and thyroid antibodies. Choose Comprehensive for thyroid function, antibodies, Graves’ markers, thyroid binding, and iodine context.

Important Note

This panel is designed to help evaluate selected biomarkers related to thyroid function, thyroid hormone production, thyroid signaling, active thyroid hormone availability, thyroid conversion, and autoimmune thyroid patterns. It is not intended to diagnose, treat, cure, or prevent disease by itself. Results should be reviewed with a licensed healthcare provider.

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