Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel

The Stress, Cortisol, Sleep & Burnout Comprehensive Lab Panel includes 46 tests and 153 biomarkers to support broad review of stress hormones, cortisol patterns, fatigue, poor sleep, burnout-related wellness, thyroid function, sex hormones, blood sugar stability, inflammation, iron status, nutrients, methylation, mitochondrial recovery, cardiometabolic risk, kidney and urine health, liver function, mineral balance, and metabolic stress.

Blood, Urine, Serum, Plasma-Unspecified Vial Pour, Other, Random
Phlebotomist
Stress Cortisol Panel, Burnout Lab Panel, Sleep and Stress Blood Test, Cortisol Blood Test Panel, Fatigue and Stress Panel, Adrenal Stress Panel, Stress Hormone Panel, Burnout Blood Test, Cortisol and Fatigue Panel

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: ACTH, ACTH Plasma, Adrenocorticotropic Hormone, Corticotropin, Cosyntropin

Acth, Plasma

Also known as: Microalbumin Random Urine with Creatinine

Creatinine, Random Urine

Microalbumin

Microalbumin/Creatinine

Also known as: ANA, ANA Screen IFA with Reflex to Titer and Pattern IFA, ANA with Reflux

ANA Screen, IFA

The antinuclear antibody (ANA) test is ordered to help screen for autoimmune disorders and is most often used as one of the tests to diagnose systemic lupus erythematosus (SLE).

Apolipoprotein B

Also known as: Bilirubin Fractionated

Bilirubin, Direct

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bilirubin, Indirect

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Also known as: C-Reactive Protein, CReactive Protein CRP, CRP

C-REACTIVE PROTEIN

C-reactive protein is produced by the liver. The level of CRP rises when there is inflammation throughout the body.

Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)

NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.

Absolute Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Absolute Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Absolute Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Absolute Eosinophils

Eosinophils (eos) respond to infections caused by parasites and play a role in allergic reactions (hypersensitivities)

Absolute Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Absolute Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Absolute Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

Absolute Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Absolute Neutrophils

Neutrophils (neu) normally make up the largest number of circulating WBCs. They move into an area of damaged or infected tissue, where they engulf and destroy bacteria or sometimes fungi. Young neutrophils, recently released into circulation, are called bands.

Absolute Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Absolute Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Eosinophils

Eosinophils are specialized white blood cells produced in the bone marrow and released into the bloodstream, where they normally make up only 0–6 % of circulating leukocytes. Their cytoplasm is packed with reddish‑orange granules that contain potent enzymes (e.g., major basic protein, eosinophil cationic protein) and inflammatory mediators. When the immune system detects large, multicellular invaders—such as helminth (worm) parasites—eosinophils migrate out of the blood and surround the pathogen, releasing these granule contents to damage the parasite’s outer surface and aid its destruction. Beyond parasite defense, eosinophils act as key orchestras of the allergic response. They accumulate in tissues exposed to allergens (airways in asthma, skin in eczema, GI tract in eosinophilic esophagitis) and secrete cytokines and lipid mediators that amplify inflammation, recruit additional immune cells, and contribute to symptoms like swelling, mucus production, and itching. Because of this pro‑inflammatory role, persistently elevated eosinophil counts—termed eosinophilia—can signal allergic disorders, drug hypersensitivity, or certain autoimmune and malignant conditions. Conversely, counts drop toward zero after glucocorticoid therapy or in acute stress states, reflecting the cells’ sensitivity to hormonal and immune regulation.

Hematocrit

Hematocrit is a blood test that measures the percentage of the volume of whole blood that is made up of red blood cells. This measurement depends on the number of red blood cells and the size of red blood cells.

Hemoglobin

Serum hemoglobin is a blood test that measures the level of free hemoglobin in the liquid part of the blood (the serum). Free hemoglobin is the hemoglobin outside of the red blood cells. Most of the hemoglobin is found inside the red blood cells, not in the serum.

Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

MCH

Mean corpuscular hemoglobin (MCH) is a calculation of the average amount of oxygen-carrying hemoglobin inside a red blood cell.

MCHC

Mean corpuscular hemoglobin concentration (MCHC) is a calculation of the average percentage of hemoglobin inside a red cell.

MCV

Mean corpuscular volume (MCV) is a measurement of the average size of RBCs.

Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

MPV

Mean Platelet Volume (MPV) - When it indicates average size of platelets are small; older platelets are generally smaller than younger ones and a low MPV may mean that a condition is affecting the production of platelets by the bone marrow. When it indicates a high number of larger, younger platelets in the blood; this may be due to the bone marrow producing and releasing platelets rapidly into circulation.

Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Neutrophils

Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed.

Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Platelet Count

A platelet count is a test to measure how many platelets you have in your blood. Platelets help the blood clot. They are smaller than red or white blood cells.

Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

RDW

Red cell distribution width (RDW), which may be included in a CBC, is a calculation of the variation in the size of RBCs.

Reactive Lymphocytes (Only Reported If Detected)

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Red Blood Cell Count

An RBC count is a blood test that tells how many red blood cells (RBCs) you have. RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

White Blood Cell Count

A WBC count is a test to measure the number of white blood cells (WBCs) in the blood. WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

Also known as: Copper Oxide, Wilson's Disease

Ceruloplasmin

Ceruloplasmin is a copper-containing protein. Lower-than-normal ceruloplasmin levels may be due to: chronic liver disease, intestinal malabsorption, malnutrition, nephrotic syndrome and Wilson's copper storage disease (rare). Higher-than-normal ceruloplasmin levels may be due to: acute and chronic infections, lymphoma, pregnancy, rheumatoid arthritis and use of birth control pills.

Also known as: CoQ10

Coenzyme Q10

Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Albumin/Globulin Ratio

The ratio of albumin to globulin (A/G ratio) is calculated from measured albumin and calculated globulin (total protein - albumin). Normally, there is a little more albumin than globulins, giving a normal A/G ratio of slightly over 1. Because disease states affect the relative amounts of albumin and globulin, the A/G ratio may provide a clue as to the cause of the change in protein levels. A low A/G ratio may reflect overproduction of globulins, such as seen in multiple myeloma or autoimmune diseases, or underproduction of albumin, such as may occur with cirrhosis, or selective loss of albumin from the circulation, as may occur with kidney disease (nephrotic syndrome). A high A/G ratio suggests underproduction of immunoglobulins as may be seen in some genetic deficiencies and in some leukemias. More specific tests, such as liver enzyme tests and serum protein electrophoresis, must be performed to make an accurate diagnosis. With a low total protein that is due to plasma expansion (dilution of the blood), the A/G ratio will typically be normal because both albumin and globulin will be diluted to the same extent.

Alkaline Phosphatase

Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone.

Alt

Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.

AST

AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bun/Creatinine Ratio

A ratio between a person’s BUN and blood creatinine to help determine what is causing these concentrations to be higher than normal. The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration. It may also be seen with increased protein, from gastrointestinal bleeding, or increased protein in the diet. The ratio may be decreased with liver disease (due to decrease in the formation of urea) and malnutrition.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.

Carbon Dioxide

CO2 is carbon dioxide. Measures the amount of carbon dioxide in the liquid part of your blood, called the serum. In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.

Chloride

Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance. This is a measure of the amount of chloride in the fluid portion (serum) of the blood.

Creatinine

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys work.

Egfr African American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

Egfr Non-Afr. American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

GFR-AFRICAN AMERICAN

GFR-NON AFRICAN AMERICAN

Globulin

Globulins is the collective term for most blood proteins other than albumin. Identifying the types of globulins can help diagnose certain disorders. Globulins are roughly divided into three groups: alpha, beta, and gamma globulins. Gamma globulines include various types of antibodies such as immunoglobulins (Ig) M, G, and A.

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Potassium

Potassium is a mineral that the body needs to work normally. It helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Protein, Total

The total protein is the total amount of two classes of proteins, albumin and globulin that are found in the fluid portion of your blood. Proteins are important parts of all cells and tissues. Your albumin helps prevent fluid from leaking out of blood vessels and your globulins are an important part of your immune system.

Sodium

Sodium is a substance that the body needs to work properly it is vital to normal body processes, including nerve and muscle function

Urea Nitrogen (Bun)

BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down. BUN measures the amount of urea nitrogen in the blood.

Copper

Also known as: Cortisol AM

Cortisol, A.M.

A cortisol level is a blood test that measures the amount of cortisol, a steroid hormone produced by the adrenal gland. The test is done to check for increased or decreased cortisol production. Cortisol is a steroid hormone released from the adrenal gland in response to ACTH, a hormone from the pituitary gland in the brain. Cortisol affects many different body systems. It plays a role in: bone, circulatory system, immune system. metabolism of fats, carbohydrates, and protein. ervous system and stress responses.

CYSTATIN C

eGFR

Also known as: Dehydroepiandrosterone Sulfate, DHEA SO4, DHEA Sulfate Immunoassay, DHEAS, Transdehydroandrosterone

DHEA SULFATE

DHEA-sulfate test measures the amount of DHEA-sulfate in the blood. DHEA-sulfate is a weak male hormone (androgen) produced by the adrenal gland in both men and women.

Estradiol

Estradiol (estradiol-17 beta, E2) is part of an estrogen that is a group of steroids that regulate the menstrual cycle and function as the main female sex hormones. Estrogens are responsible for the development of female sex organs and secondary sex characteristics and are tied to the menstrual cycle and pregnancy. They are considered the main sex hormones in women and are present in small quantities in men. Estradiol (E2) is the predominant form of estrogen and is produced primarily in the ovaries with additional amounts produced by the adrenal glands in women and in the testes and adrenal glands in men. Estradiol levels are used in evaluating ovarian function. Estradiol levels are increased in cases of early (precocious) puberty in girls and gynecomastia in men. Its main use has been in the differential diagnosis of amenorrhea – for example, to determine whether the cause is menopause, pregnancy, or a medical problem. In assisted reproductive technology (ART), serial measurements are used to monitor follicle development in the ovary in the days prior to in vitro fertilization. Estradiol is also sometimes used to monitor menopausal hormone replacement therapy.

Ferritin

Ferritin is a protein found inside cells that stores iron so your body can use it later. A ferritin test indirectly measures the amount of iron in your blood. The amount of ferritin in your blood (serum ferritin level) is directly related to the amount of iron stored in your body.

Also known as: Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH), Follicle Stimulating Hormone and Luteinizing Hormone

Fsh

Lh

Also known as: Gamma Glutamyl Transferase GGT, Gamma-Glutamyl Transferase, Gamma-Glutamyl Transpeptidase, Gamma-GT, GGTP, GTP

Ggt

Gamma-glutamyl transpeptidase (GGT) is a test to measure the amount of the enzyme GGT in the blood.

Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c

HEMOGLOBIN A1C

The A1c test evaluates the average amount of glucose in the blood over the last 2 to 3 months. It does this by measuring the concentration of glycated (also often called glycosylated) hemoglobin A1c. Hemoglobin is an oxygen-transporting protein found inside red blood cells (RBCs). There are several types of normal hemoglobin, but the predominant form – about 95-98% – is hemoglobin A. As glucose circulates in the blood, some of it spontaneously binds to hemoglobin A. The hemoglobin molecules with attached glucose are called glycated hemoglobin. The higher the concentration of glucose in the blood, the more glycated hemoglobin is formed. Once the glucose binds to the hemoglobin, it remains there for the life of the red blood cell – normally about 120 days. The predominant form of glycated hemoglobin is referred to as HbA1c or A1c. A1c is produced on a daily basis and slowly cleared from the blood as older RBCs die and younger RBCs (with non-glycated hemoglobin) take their place. This test is used to monitor treatment in someone who has been diagnosed with diabetes. It helps to evaluate how well their glucose levels have been controlled by treatment over time. This test may be used to screen for and diagnose diabetes or risk of developing diabetes. In 2010, clinical practice guidelines from the American Diabetes Association (ADA) stated that A1c may be added to fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) as an option for diabetes screening and diagnosis. For monitoring purposes, an A1c of less than 7% indicates good glucose control and a lower risk of diabetic complications for the majority of diabetics. However, in 2012, the ADA and the European Association for the Study of Diabetes (EASD) issued a position statement recommending that the management of glucose control in type 2 diabetes be more "patient-centered." Data from recent studies have shown that low blood sugar (hypoglycemia) can cause complications and that people with risk of severe hypoglycemia, underlying health conditions, complications, and a limited life expectancy do not necessarily benefit from having a stringent goal of less than 7% for their A1c. The statement recommends that people work closely with their doctor to select a goal that reflects each person's individual health status and that balances risks and benefits.

Also known as: Homocysteine, Homocysteine Cardiovascular

HOMOCYSTEINE,

Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP

Hs Crp

A high-sensitivity CRP (hs-CRP) test may be used by itself, in combination with other cardiac risk markers, or in combination with a lipoprotein-associated phospholipase A2 (Lp-PLA2) test that evaluates vascular inflammation. The hs-CRP test accurately detects low concentrations of C-reactive protein to help predict a healthy person's risk of cardiovascular disease (CVD). High-sensitivity CRP is promoted by some as a test for determining a person's risk level for CVD, heart attacks, and strokes. The current thinking is that hs-CRP can play a role in the evaluation process before a person develops one of these health problems.

Also known as: Insulin (fasting)

Insulin

Insulin is a hormone that is produced and stored in the beta cells of the pancreas. It is vital for the transportation and storage of glucose at the cellular level, helps regulate blood glucose levels, and has a role in lipid metabolism. When blood glucose levels rise after a meal, insulin is released to allow glucose to move into tissue cells, especially muscle and adipose (fat) cells, where is it is used for energy production. Insulin then prompts the liver to either store the remaining excess blood glucose as glycogen for short-term energy storage and/or to use it to produce fatty acids. The fatty acids are eventually used by adipose tissue to synthesize triglycerides to form the basis of a longer term, more concentrated form of energy storage. Without insulin, glucose cannot reach most of the body's cells. Without glucose, the cells starve and blood glucose levels rise to unhealthy levels. This can cause disturbances in normal metabolic processes that result in various disorders, including kidney disease, cardiovascular disease, and vision and neurological problems. Thus, diabetes, a disorder associated with decreased insulin effects, is eventually a life-threatening condition.

Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC

% Saturation

Iron Binding Capacity

Total iron binding capacity (TIBC) is a blood test to see if you may have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.

Iron, Total

Iron is a mineral that our bodies need for many functions. For example, iron is part of hemoglobin, a protein which carries oxygen from our lungs throughout our bodies. It helps our muscles store and use oxygen. Iron is also part of many other proteins and enzymes. Your body needs the right amount of iron. If you have too little iron, you may develop iron deficiency anemia. Causes of low iron levels include blood loss, poor diet, or an inability to absorb enough iron from foods. People at higher risk of having too little iron are young children and women who are pregnant or have periods.

Also known as: Lipid Panel with Ratios (fasting), Lipid Profile with Ratios (fasting), Lipids

Chol/HDLC Ratio

Cholesterol, Total

Cholesterol is a waxy, fat-like substance that occurs naturally in all parts of the body. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can combine with other substances in the blood and stick to the walls of your arteries. This is called plaque. Plaque can narrow your arteries or even block them. High levels of cholesterol in the blood can increase your risk of heart disease. Your cholesterol levels tend to rise as you get older. There are usually no signs or symptoms that you have high blood cholesterol, but it can be detected with a blood test. You are likely to have high cholesterol if members of your family have it, if you are overweight or if you eat a lot of fatty foods. You can lower your cholesterol by exercising more and eating more fruits and vegetables. You also may need to take medicine to lower your cholesterol.

HDL Cholesterol

LDL-Cholesterol

LDL/HDL Ratio

Non HDL Cholesterol

Triglycerides

Triglycerides are a form of fat and a major source of energy for the body. This test measures the amount of triglycerides in the blood. Most triglycerides are found in fat (adipose) tissue, but some triglycerides circulate in the blood to provide fuel for muscles to work. After a person eats, an increased level of triglycerides is found in the blood as the body converts the energy not needed right away into fat. Triglycerides move via the blood from the gut to adipose tissue for storage. In between meals, triglycerides are released from fat tissue to be used as an energy source for the body. Most triglycerides are carried in the blood by lipoproteins called very low density lipoproteins (VLDL). High levels of triglycerides in the blood are associated with an increased risk of developing cardiovascular disease (CVD), although the reason for this is not well understood. Certain factors can contribute to high triglyceride levels and to risk of CVD, including lack of exercise, being overweight, smoking cigarettes, consuming excess alcohol, and medical conditions such as diabetes and kidney disease.

Magnesium

Also known as: Magnesium RBC

Magnesium, Rbc

About half of the body's magnesium is found in bone. The other half is found inside cells of body tissues and organs. Magnesium is needed for nearly all chemical processes in the body. It helps maintain normal muscle and nerve function, and keeps the bones strong. Magnesium is also needed for the heart to function normally and to help regulate blood pressure. Magnesium also helps the body control blood sugar level and helps support the body's defense (immune) system.

Methylmalonic Acid

ARACHIDONIC ACID

ARACHIDONIC ACID/EPA

DHA

DPA

EPA

EPA+DPA+DHA

LINOLEIC ACID

OMEGA-3 TOTAL

OMEGA-6 TOTAL

OMEGA-6/OMEGA-3 RATIO

Also known as: Inorganic Phosphate, P, Phosphate as Phosphorus, Phosphorus, PO4

Phosphate (As Phosphorus)

This test is performed to see how much phosphorus in your blood. Kidney, liver, and certain bone diseases can cause abnormal phosphorus levels.

Also known as: Pregnenolone LCMSMS

Pregnenolone, LC/MS/MS

Also known as: Progesterone Immunoassay

Progesterone

Serum progesterone is a test to measure the amount of progesterone in the blood. Progesterone is a hormone produced mainly in the ovaries. In women, progesterone plays a vital role in pregnancy. After an egg is released by the ovaries (ovulation), progesterone helps make the uterus ready for implantation of a fertilized egg. It prepares the womb (uterus) for pregnancy and the breasts for milk production. Men produce some amount of progesterone, but it probably has no normal function except to help produce other steroid hormones.

Also known as: PRL

Prolactin

Prolactin is a hormone produced by the anterior portion of the pituitary gland, a grape-sized organ found at the base of the brain. Prolactin secretion is regulated and inhibited by the brain chemical dopamine. Normally present in low amounts in men and non-pregnant women, prolactin's primary role is to promote lactation (breast milk production). Prolactin levels are usually high throughout pregnancy and just after childbirth. During pregnancy, the hormones prolactin, estrogen, and progesterone stimulate breast milk development. Following childbirth, prolactin helps initiate and maintain the breast milk supply. If a woman does not breastfeed, her prolactin level soon drops back to pre-pregnancy levels. If she does nurse, suckling by the infant plays an important role in the release of prolactin. There is a feedback mechanism between how often the baby nurses and the amount of prolactin secreted by the pituitary as well as the amount of milk produced. Another common cause of elevated prolactin levels is a prolactinoma, a prolactin-producing tumor of the pituitary gland. Prolactinomas are the most common type of pituitary tumor and are usually benign. They develop more frequently in women but are also found in men. Problems resulting from them can arise both from the unintended effects of excess prolactin, such as milk production in the non-pregnant woman (and rarely, man) and from the size and location of the tumor. If the anterior pituitary gland and/or the tumor enlarge significantly, it can put pressure on the optic nerve, causing headaches and visual disturbances, and it can interfere with the other hormones that the pituitary gland produces. In women, prolactinomas can cause infertility and irregularities in menstruation; in men, these tumors can cause a gradual loss in sexual function and libido. If left untreated, prolactinomas may eventually damage the tissues around them.

Also known as: "Biointact" PTH, Intact PTH, Parathyroid Hormone , Parathyroid Hormone (PTH), PTH, PTH Intact without Calcium

PARATHYROID HORMONE,

PTH stands for parathyroid hormone. It is a protein hormone released by the parathyroid gland. Parathyroid hormone controls calcium, phosphorus, and vitamin D levels in the blood and bone. Release of PTH is controlled by the level of calcium in the blood. Low blood calcium levels cause increased PTH to be released, while high blood calcium levels block PTH release.

Vitamin D, 25-Oh, D2

Vitamin D2 ((ergocalciferol,) is found in fortified foods and in most vitamin preparations and supplements. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D2 is effective when it is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, D3

Vitamin D3 (cholecalcifero) which comes from animals. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D3 are is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Also known as: ESR, SED RATE, Sed Rate by Modified Westergren ESR

Sed Rate By Modified

Erythrocyte sedimentation rate (ESR) is an indirect measure of the degree of inflammation present in the body. It actually measures the rate of fall (sedimentation) of erythrocytes (red blood cells) in a sample of blood.

Selenium

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Also known as: Testosterone Total And Free And Sex Hormone Binding Globulin

Free Testosterone

In many cases, measurement of total testosterone provides the doctor with adequate information. However, in certain cases, for example when the level of SHBG is abnormal, a test for free or bioavailable testosterone may be performed as it may more accurately reflect the presence of a medical condition.

Sex Hormone Binding

The sex hormone binding globulin (SHBG) test measures the concentration of SHBG in the blood. SHBG is a protein that is produced by the liver and binds tightly to testosterone, dihydrotestosterone (DHT), and estradiol (an estrogen). In this bound state, it transports them in the blood as an inactive form. The amount of SHBG in circulation is affected by age and sex, by decreased or increased testosterone or estrogen production and can be affected by certain diseases and conditions such as liver disease, hyperthyroidism or hypothyroidism, and obesity. Changes in SHBG levels can affect the amount of testosterone that is available to be used by the body's tissues. A total testosterone test does not distinguish between bound and unbound testosterone but determines the overall quantity of testosterone. If a person's SHBG level is not normal, then the total testosterone may not be an accurate representation of the amount of testosterone that is available to the person's tissues.

TESTOSTERONE, TOTAL,

A testosterone test measures the amount of the male hormone, testosterone, in the blood. Both men and women produce this hormone. In males, the testicles produce most of the testosterone in the body. Levels are most often checked to evaluate signs of low testosterone: In boys -- early or late puberty and in men -- impotence, low level of sexual interest, infertility, thinning of the bones In females, the ovaries produce most of the testosterone and levels are most often checked to evaluate signs of higher testosterone levels, such as: decreased breast size, excess hair growth, increased size of the clitoris. irregular or absent menstrual periods and male-pattern baldness or hair thinning.

Thyroglobulin Antibodies

Measurement of thyroglobulin antibodies is useful in the diagnosis and management of a variety of thyroid disorders including Hashimoto's thyroiditis, Graves Disease and certain types of goiter.

Thyroid Peroxidase

Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

Also known as: Serum Urate, UA

Uric Acid

Uric acid is a chemical created when the body breaks down substances called purines. Purines are found in some foods and drinks. These include liver, anchovies, mackerel, dried beans and peas, and beer. Most uric acid dissolves in blood and travels to the kidneys. From there, it passes out in urine. If your body produces too much uric acid or doesn't remove enough if it, you can get sick. A high level of uric acid in the blood is called hyperuricemia.

Also known as: UA, with Reflex to Culture, Urinalysis Complete with Reflex to Culture, Urine Analysis, with Reflex to Culture

Amorphous Sediment (Only Reported If Detected)

Appearance

Bacteria

Bacteria are living things that have only one cell. Most bacteria won't hurt you - less than 1 percent of the different types make people sick. Many are helpful. Some bacteria help to digest food, destroy disease-causing cells, and give the body needed vitamins. But infectious bacteria can make you ill. They reproduce quickly in your body. Many give off chemicals called toxins, which can damage tissue and make you sick. Examples of bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli.

Bilirubin

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Calcium Oxalate Crystals (Only Reported If Detected)

Calcium oxalate is a chemical compound that forms envelope-shaped crystals. A major constituent of human kidney stones.

Casts (Only Reported If Detected)

Urinary casts are cylindrical structures produced by the kidney and present in the urine in certain disease states. They form in the distal convoluted tubule and collecting ducts of nephrons, then dislodge and pass into the urine, where they can be detected by microscopy.

Color

Crystals (Only Reported If Detected)

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Granular Cast (Only Reported If Detected)

The second-most common type of cast, granular casts can result either from the breakdown of cellular casts or the inclusion of aggregates of plasma proteins (e.g., albumin) or immunoglobulin light chains. Depending on the size of inclusions, they can be classified as fine or coarse, though the distinction has no diagnostic significance. Their appearance is generally more cigar-shaped and of a higher refractive index than hyaline casts. While most often indicative of chronic renal disease, these casts, as with hyaline casts, can also be seen for a short time following strenuous exercise

Hyaline Cast

Urinary casts are tiny tube-shaped particles. Urinary casts may be made up of white blood cells, red blood cells, kidney cells, or substances such as protein or fat. The most common type of cast, hyaline casts are solidified Tamm-Horsfall mucoprotein secreted from the tubular epithelial cells of individual nephrons. Low urine flow, concentrated urine, or an acidic environment can contribute to the formation of hyaline casts, and, as such, they may be seen in normal individuals in dehydration or vigorous exercise. Hyaline casts are cylindrical and clear, with a low refractive index,

Ketones

Ketones are substances produced in the liver when fat cells break down in the blood. A serum ketone test is a measurement of how many ketones are in the blood.

Leukocyte Esterase

Nitrite

Occult Blood

The test looks for hidden (occult) blood in a specimen sample. It can find blood even if you cannot see it yourself.

Ph

Level of acid

Protein

Body fluids contain many different proteins that serve diverse functions such as transport of nutrients, removal of toxins, control of metabolic processes, and defense against invaders. Protein electrophoresis is a method for separating these proteins based on their size and electrical charge. When body fluids are separated by electrophoresis, they form a characteristic pattern of bands of different widths and intensities, reflecting the mixture of proteins present. This pattern is divided into five fractions, called albumin, alpha 1, alpha 2, beta, and gamma. In some cases, the beta fraction is further divided into beta 1 and beta 2. Albumin, which is produced in the liver, accounts for about 60% of the protein in the blood. "Globulins" is a collective term used to refer to proteins other than albumin. With the exception of the immunoglobulins and some complement proteins, most of the globulins are also produced in the liver. Immunofixation electrophoresis (IFE) is a method used to identify abnormal bands seen on serum, urine, or CSF protein electrophoresis, as to which type of antibody (immunoglobulin) is present.

Rbc

RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

Reducing Substances (Only Reported If Detected)

Renal Epithelial Cells (Only Reported If Detected)

Specific Gravity

Squamous Epithelial Cells

Transitional Epithelial (Only Reported If Detected)

Triple Phosphate Crystals (Only Reported If Detected)

Struvite stones (triple phosphate/magnesium ammonium phosphate) - about 10–15% of urinary calculi are composed of struvite (ammonium magnesium phosphate, NH4MgPO4·6H2O).[44] Struvite stones (also known as "infection stones", urease or triple-phosphate stones), form most often in the presence of infection by urea-splitting bacteria

Uric Acid Crystals (Only Reported If Detected)

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

WBC

WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

YEAST (Only Reported If Detected)

Candida is the scientific name for yeast. It is a fungus that lives almost everywhere, including in your body. Usually, your immune system keeps yeast under control. If you are sick or taking antibiotics, it can multiply and cause an infection.

Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid

Folate, Serum

Folate is part of the B complex of vitamins and is measures the levels of folate in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Folate is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis.. A deficiency inr folate can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow.

Vitamin B12

Vitamin B12 is part of the B complex of vitamins and measurea the levels of vitamin B12 in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Cobalamine, or vitamin B12, is found in animal products such as red meat, fish, poultry, milk, yogurt, and eggs and is not produced in the human body. In recent years, fortified cereals, breads, and other grain products have also become important dietary sources of B12. Vitamin B12 is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis. B12 is important for nerve health. A deficiency in B12 can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow. B12 deficiency can lead to varying degrees of neuropathy, nerve damage that can cause tingling and numbness in the affected person's hands and feet.

Also known as: B6, B6 Vitamin, Pyridoxal, Pyridoxal Phosphate, Pyridoxal Phosphate (PLP), Vitamin B6 Pyridoxal Phosphate

Vitamin B6

Also known as: ZN, Plasma

Zinc

*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through a national lab. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel panel contains 46 tests with 153 biomarkers .

Overview

The Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel is designed for people who want a broad lab-based review of biomarkers related to stress-response hormones, cortisol patterns, fatigue, poor sleep, burnout-related wellness, thyroid function, sex hormone balance, blood sugar stability, inflammation, iron status, nutrient status, methylation, mitochondrial recovery, cardiometabolic risk, kidney and urine health, liver function, mineral balance, and metabolic stress.

This panel includes 46 tests and 153 biomarkers to support provider-guided conversations about stress physiology, low energy, poor recovery, sleep disruption, mood changes, cravings, energy crashes, hormone patterns, thyroid overlap, nutrient deficiencies, and metabolic resilience.

This panel does not diagnose burnout, adrenal insufficiency, Cushing syndrome, insomnia, sleep apnea, thyroid disease, hormone imbalance, depression, anxiety, or any medical condition by itself. Suspected adrenal insufficiency and Cushing syndrome require specific clinical evaluation and confirmatory testing, and suspected sleep apnea is evaluated with sleep testing such as polysomnography or home sleep apnea testing. 


Why Order This Panel?

The Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel may be helpful for people who want more than a basic cortisol or fatigue test and want a broader look at body systems that may influence stress resilience, sleep quality, recovery, energy, mood, and metabolic balance.

This panel may help provide insight into:

  • ACTH and morning cortisol patterns
  • DHEA-S and pregnenolone stress-hormone pathway context
  • Thyroid function and thyroid autoimmunity
  • Sex hormone and life-stage hormone patterns
  • Blood sugar, insulin, and A1c patterns
  • Inflammation with CRP, hs-CRP, and ESR
  • Iron storage and iron availability
  • Vitamin D, B12, folate, MMA, B6, magnesium, zinc, selenium, copper, and ceruloplasmin status
  • CoQ10 and omega fatty acid status
  • Cholesterol, ApoB, and cardiometabolic risk patterns
  • Kidney filtration, urine albumin, urinalysis, and urine reflex culture context
  • Liver and bile-flow markers
  • Bone-mineral and phosphorus patterns
  • Uric acid and metabolic stress

This Panel May Be Helpful For People With

  • Chronic stress or burnout-like symptoms
  • Poor sleep or non-restorative sleep
  • Fatigue or low energy
  • Brain fog or poor focus
  • Energy crashes
  • Sugar cravings or stress eating
  • Poor recovery after exercise or illness
  • Mood changes
  • Low motivation
  • Weight changes or belly fat
  • Low stamina
  • Hormone-related sleep or mood concerns
  • Thyroid symptoms
  • Inflammation concerns
  • Low iron or ferritin concerns
  • Vitamin D, B12, magnesium, zinc, selenium, or B6 concerns
  • Interest in a broad stress, sleep, fatigue, and recovery biomarker review

Which Tier Is Right for Me?

Essential Lab Panel

The Stress, Cortisol, Sleep & Burnout - Essential Lab Panel is best for people who want a focused first-step review of cortisol, fatigue, thyroid function, blood sugar, inflammation, iron status, vitamin D, B12/folate, magnesium, CMP, CBC, and uric acid.

Choose Essential if you want an accessible baseline for stress-related fatigue, poor sleep, blood sugar stability, thyroid overlap, inflammation, iron status, and nutrient support.

Advanced Lab Panel

The Stress, Cortisol, Sleep & Burnout - Advanced Lab Panel is best for people who want deeper insight into ACTH, DHEA-S, pregnenolone, Free T3, thyroid antibodies, methylation, RBC magnesium, CoQ10, ApoB, kidney/urine markers, liver/bile markers, mineral balance, PTH/phosphate, and ESR.

Choose Advanced if symptoms are persistent or if you want broader review of stress-response hormones, thyroid overlap, methylation, nutrient status, kidney/urine health, liver function, inflammation, and recovery.

Comprehensive Lab Panel

The Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel is the broadest option. It includes 46 tests and 153 biomarkers and adds premium markers for sex hormones, life-stage hormones, prolactin, copper/ceruloplasmin, OMEGACHECK™, ANA screening, and full-system stress, sleep, burnout, and recovery review.

Choose Comprehensive if you want the widest review of stress hormones, cortisol patterns, sleep/fatigue overlap, thyroid function, sex hormones, inflammation, iron status, nutrients, methylation, mitochondrial recovery, metabolic stress, kidney/urine health, liver function, omega status, and hormone/life-stage patterns.


Tests Included and Why They Matter

Stress Hormones and HPA-Axis Context

ACTH, Plasma

ACTH is a pituitary hormone that signals the adrenal glands to produce cortisol.

This test is included because ACTH can provide pituitary-adrenal signaling context when reviewed with morning cortisol. It may help support provider-guided discussion of stress-response patterns, fatigue, low resilience, and adrenal-axis context.

Cortisol, A.M.

Morning cortisol provides a snapshot of cortisol during the time of day when cortisol is typically expected to be higher.

This test is included because cortisol is central to stress-response physiology, sleep-wake rhythm, energy, blood sugar patterns, and resilience. It should be interpreted with ACTH, symptoms, medications, sleep timing, and provider guidance.

DHEA Sulfate, Immunoassay

DHEA-S is an adrenal androgen marker.

This test is included because DHEA-S may provide context for adrenal hormone patterns, stress physiology, energy, aging-related hormone changes, DHEA supplementation, and resilience-related wellness.

Pregnenolone, LC/MS/MS

Pregnenolone is a steroid hormone precursor.

This test is included because it may provide premium context for steroid hormone pathways, adrenal hormone production, stress physiology, and hormone balance. It should be interpreted with cortisol, DHEA-S, sex hormones, symptoms, and provider guidance.


Sleep, Mood and Life-Stage Hormone Context

Estradiol

Estradiol is a major estrogen hormone.

This test is included because estradiol may provide context for sleep quality, mood, temperature regulation, cycle or menopause-related symptoms, bone health, and hormone balance. Interpretation differs by sex, age, cycle timing, menopause status, and hormone therapy use.

Progesterone, Immunoassay

Progesterone is a reproductive hormone that varies by sex, menstrual cycle timing, pregnancy status, menopause status, and hormone therapy use.

This test is included because progesterone may provide context for sleep, mood, cycle timing, perimenopause/menopause discussions, and hormone-balance review.

Testosterone, Total and Free and Sex Hormone Binding Globulin

This test evaluates total testosterone, free testosterone, and SHBG.

It is included because testosterone availability may provide context for energy, libido, mood, muscle mass, body composition, recovery, motivation, and sleep-related wellness discussions. Interpretation differs by sex, age, symptoms, and hormone therapy use.

FSH and LH

FSH and LH are pituitary hormones involved in reproductive hormone signaling.

These tests are included because they may provide life-stage and hormone-axis context, especially when stress, sleep, fatigue, cycle changes, menopause transition, low testosterone patterns, or reproductive hormone symptoms are part of the discussion.

Prolactin

Prolactin is a pituitary hormone that can affect reproductive hormone signaling.

This test is included because prolactin may provide context for libido changes, menstrual changes, testosterone patterns, pituitary-related hormone patterns, and broader hormone/sleep overlap.


Thyroid, Energy and Autoimmune Thyroid Context

TSH

TSH is a key thyroid screening marker.

This test is included because thyroid patterns can overlap with fatigue, poor sleep, low mood, weight changes, cold intolerance, heat intolerance, brain fog, and low energy.

T4, Free

Free T4 measures available thyroxine, a major thyroid hormone.

This test is included because it adds thyroid hormone production context beyond TSH alone and may help clarify thyroid patterns when fatigue, metabolism, sleep, or energy symptoms are present.

T3, Free

Free T3 measures available active thyroid hormone.

This test is included because Free T3 may provide context for energy output, metabolism, body temperature, fatigue, and recovery.

Thyroid Peroxidase and Thyroglobulin Antibodies

These antibodies help evaluate autoimmune thyroid patterns.

This test is included because autoimmune thyroid activity may overlap with fatigue, poor sleep, mood changes, weight changes, hair changes, and other thyroid-related concerns.


Blood Sugar, Metabolic and Cardiovascular Stress

Comprehensive Metabolic Panel, CMP

The CMP evaluates glucose, liver enzymes, kidney markers, electrolytes, calcium, albumin, total protein, and other metabolic markers.

This test is included because stress, fatigue, poor sleep, and burnout-like symptoms benefit from a broad organ-function baseline. CMP provides context for glucose, liver function, kidney function, hydration, electrolytes, calcium, albumin, and protein status.

Hemoglobin A1c

Hemoglobin A1c reflects longer-term blood sugar patterns.

This test is included because blood sugar regulation may overlap with energy crashes, cravings, poor sleep, fatigue, and metabolic stress.

Insulin

Insulin helps move glucose from the bloodstream into cells.

This test is included because fasting insulin may provide insulin-resistance context when symptoms include cravings, belly fat, energy crashes, fatigue, or stress eating.

Lipid Panel with Ratios

The Lipid Panel with Ratios evaluates cholesterol, triglycerides, HDL, LDL, and cholesterol ratios.

This test is included because poor sleep, stress, thyroid patterns, insulin resistance, and weight changes can overlap with cardiometabolic risk.

Apolipoprotein B

ApoB reflects the number of atherogenic cholesterol-carrying particles.

This test is included because ApoB may provide deeper cardiometabolic risk context than LDL cholesterol alone.

Uric Acid

Uric acid is a metabolic waste product.

This test is included because uric acid may provide context for metabolic stress, gout risk, kidney stone risk, blood pressure, kidney function, and cardiometabolic wellness.


Inflammation and Immune Context

C-Reactive Protein, CRP

CRP is a blood marker that can rise when inflammation is present.

This test is included because inflammation may overlap with fatigue, poor recovery, metabolic stress, sleep disruption, and general wellness. CRP does not identify the cause of inflammation by itself and should be interpreted with symptoms and other findings.

hs-CRP

High-sensitivity C-reactive protein is a more sensitive inflammation marker often used for low-grade inflammation and cardiometabolic context.

This test is included because low-grade inflammation may overlap with stress, fatigue, poor sleep, metabolic risk, and recovery.

Sed Rate by Modified Westergren, ESR

ESR is a broad inflammation marker.

This test is included because it adds systemic inflammation context that may complement CRP and hs-CRP.

ANA Screen, IFA with Reflex to Titer and Pattern, IFA

ANA testing evaluates antinuclear antibody patterns and may reflex to titer and pattern when criteria are met.

This test is included because autoimmune overlap may be relevant when fatigue coexists with joint pain, rashes, dry eyes, dry mouth, or autoimmune family history. Positive ANA results can occur without autoimmune disease and should be interpreted with symptoms, exam findings, and provider guidance.

Reflex Test Notice: If reflex testing is performed, additional charges may apply.


Iron, Oxygen Delivery and Fatigue

CBC, includes Differential and Platelets

The CBC evaluates red blood cells, white blood cells, hemoglobin, hematocrit, platelets, and white blood cell types.

This test is included because blood count patterns may provide context for anemia, infection clues, immune activity, platelet changes, fatigue, and overall blood health.

Ferritin

Ferritin measures stored iron.

This test is included because ferritin may provide context for fatigue, low stamina, hair shedding, restless sleep-type concerns, inflammation, and iron storage.

Iron and Total Iron Binding Capacity, TIBC

Iron and TIBC help evaluate circulating iron and iron transport capacity.

This test is included because iron availability can provide context for oxygen delivery, fatigue, low stamina, anemia patterns, and ferritin interpretation.


Nutrients, Methylation and Recovery

QuestAssureD™ 25-Hydroxyvitamin D, D2, D3, LC/MS/MS

Vitamin D testing measures vitamin D status.

This test is included because vitamin D supports immune, bone, muscle, mood, inflammation, and calcium-balance pathways.

Vitamin B12 and Folate Panel, Serum

This panel measures vitamin B12 and folate.

B12 and folate support red blood cell production, nerve function, DNA synthesis, methylation, cognition, mood, and energy.

Methylmalonic Acid

Methylmalonic acid, or MMA, is a functional marker related to vitamin B12 status.

This test is included because MMA can provide deeper B12 interpretation when serum B12 is borderline or symptoms suggest B12-related concerns.

Homocysteine

Homocysteine is influenced by B12, folate, vitamin B6, methylation pathways, kidney function, and vascular health.

This test is included because it provides B-vitamin, methylation, vascular, cognitive, and stress-related wellness context.

Vitamin B6, Pyridoxal Phosphate

Vitamin B6 supports neurotransmitter pathways, methylation, amino acid metabolism, immune function, and energy metabolism.

This test is included because B6 may provide context for mood, energy, nerve function, and homocysteine interpretation.

Magnesium

Magnesium supports muscle function, nerve signaling, sleep, glucose metabolism, blood pressure regulation, and energy production.

This test is included because magnesium may provide sleep, stress, cramps, fatigue, recovery, and metabolic context.

Magnesium, RBC

RBC magnesium may provide deeper magnesium status context.

This test is included because deeper magnesium evaluation may be useful when sleep disruption, fatigue, cramps, stress symptoms, or muscle symptoms are present.

Zinc

Zinc supports immune function, hormone pathways, neurotransmitter pathways, thyroid support, wound healing, and recovery.

This test is included because zinc may provide immune, nervous system, recovery, and stress-related wellness context.

Selenium

Selenium supports thyroid-related pathways and antioxidant systems.

This test is included because selenium may provide thyroid, antioxidant, and recovery context.

Copper

Copper supports iron metabolism, connective tissue, antioxidant enzyme systems, neurologic function, and cellular function.

This test is included because copper may provide mineral-balance context, especially when zinc and iron markers are included.

Ceruloplasmin

Ceruloplasmin is a copper-carrying protein.

This test is included because it helps interpret copper status and supports mineral balance review.

Coenzyme Q10

CoQ10 supports mitochondrial energy production and antioxidant function.

This test is included because CoQ10 may provide context for fatigue, muscle symptoms, statin-associated muscle complaints, mitochondrial energy, and recovery.

OMEGACHECK™

OMEGACHECK™ evaluates omega fatty acid status.

This test is included because omega fatty acid patterns may provide context for inflammation balance, mood, brain health, recovery, and cardiometabolic wellness.


Kidney, Urine, Liver and Mineral Balance

Cystatin C with eGFR

Cystatin C with eGFR provides kidney filtration context beyond creatinine alone.

This test is included because kidney function may be relevant to medication/supplement safety, cardiometabolic risk, fatigue, and metabolic stress.

Albumin, Random Urine with Creatinine

This urine test evaluates albumin relative to creatinine.

It is included because urine albumin may provide kidney and vascular risk context, especially with insulin resistance, blood pressure, metabolic stress, or long-term wellness monitoring.

Urinalysis, Complete, with Reflex to Culture

A complete urinalysis evaluates urine markers such as protein, blood, glucose, ketones, specific gravity, pH, and other findings. If certain findings meet laboratory criteria, a urine culture may be performed.

This test is included because urine findings may provide hydration, kidney, glucose, ketone, protein, blood, and urine-health context.

Reflex Test Notice: If reflex urine culture is performed, additional charges may apply.

Gamma Glutamyl Transferase, GGT

GGT is a liver and bile duct enzyme.

This test is included because it may provide liver, bile-flow, alcohol, medication, supplement, fatty liver, and metabolic context.

Bilirubin, Fractionated

Bilirubin, Fractionated measures total, direct, and indirect bilirubin.

This test is included because bilirubin patterns may provide liver processing and bile-flow context beyond standard liver enzymes.

Phosphate, as Phosphorus

Phosphorus supports bone-mineral balance, ATP/energy pathways, kidney function, and vitamin D regulation.

This test is included because it adds mineral, energy, kidney, and bone-related context.

PTH, Intact without Calcium

PTH helps regulate calcium and phosphorus balance.

This test is included because PTH may provide parathyroid, vitamin D, calcium, phosphorus, bone-mineral, and fatigue-related mineral context. If available, PTH, Intact and Calcium may be preferable for paired interpretation.


Professional Reflex Testing Notice

This panel includes ANA Screen, IFA with Reflex to Titer and Pattern, IFA and Urinalysis, Complete, with Reflex to Culture. Reflex testing means the laboratory may automatically perform additional testing when initial findings meet specific criteria.

If reflex testing or urine culture is performed, additional charges may apply. Reflex results should be reviewed with a licensed healthcare provider.


Related Biomarker Patterns This Panel May Help Identify

This panel may help identify or support provider-guided review of:

  • ACTH and morning cortisol patterns
  • DHEA-S and pregnenolone patterns
  • Estradiol, progesterone, testosterone, FSH/LH, and prolactin patterns
  • TSH, Free T4, Free T3, and thyroid antibody patterns
  • A1c, insulin, glucose, and metabolic stress patterns
  • hs-CRP, CRP, ESR, and ANA screening patterns
  • Ferritin, iron, and TIBC patterns
  • Vitamin D, B12, folate, MMA, homocysteine, B6, magnesium, RBC magnesium, zinc, selenium, copper, and ceruloplasmin status
  • CoQ10 and omega fatty acid patterns
  • ApoB, lipid ratios, and cardiometabolic risk patterns
  • Cystatin C, urine albumin, urinalysis, GGT, bilirubin, phosphate, and PTH patterns

Professional Safety and Interpretation Notice

This panel is designed to support stress, cortisol, sleep, and burnout-related biomarker review. It does not diagnose burnout, adrenal insufficiency, Cushing syndrome, insomnia, sleep apnea, thyroid disease, hormone imbalance, depression, anxiety, kidney disease, liver disease, or nutrient deficiency by itself.

Results should be interpreted with a licensed healthcare provider and reviewed alongside symptoms, sleep patterns, medications, supplements, hormone therapy, thyroid medication use, menstrual cycle timing, menopause status, stress level, nutrition, exercise, alcohol use, medical history, and family history.

Do not stop or change medications, hormones, thyroid medication, cortisol-related treatment, or supplements without guidance from your healthcare provider.


How to Prepare for This Panel

Preparation may vary depending on the specific tests and lab instructions. In general:

  • Morning collection may be important for ACTH, cortisol, testosterone, and some hormones.
  • Fasting may be recommended because glucose, insulin, lipid, and metabolic markers are included.
  • Bring a list of medications, supplements, hormones, thyroid medications, sleep aids, steroids, adrenal supplements, biotin, and doses.
  • Ask your provider whether biotin should be paused before thyroid or hormone testing.
  • Note symptoms such as fatigue, poor sleep, stress, brain fog, mood changes, cravings, energy crashes, hair changes, weight changes, low libido, or poor recovery.
  • Follow all collection instructions provided with your order.

What Happens After You Receive Your Results?

After results are available, biomarkers can be organized into key categories: stress-response hormones, cortisol patterns, thyroid function, sex hormones, blood sugar stability, inflammation, iron status, nutrients, methylation, mitochondrial recovery, cardiometabolic risk, kidney/urine health, liver function, mineral balance, and metabolic stress.

During a provider review, you can discuss whether results suggest follow-up testing, sleep evaluation, medication review, hormone timing review, thyroid review, nutrition changes, supplement review, exercise recovery adjustments, stress management planning, or additional clinical evaluation.


Additional Panels to Consider

Customers interested in the Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel may also consider:

  • Stress, Cortisol, Sleep & Burnout - Essential Lab Panel
  • Stress, Cortisol, Sleep & Burnout - Advanced Lab Panel
  • Fatigue, Low Energy & Brain Fog Lab Panel
  • Thyroid & Metabolism Lab Panel
  • Men’s Testosterone, Energy & Vitality Lab Panel
  • Women’s Hormone Balance & Perimenopause Lab Panel
  • Prediabetes & Insulin Resistance Lab Panel
  • Vitamin, Mineral & Nutrient Deficiency Lab Panel
  • Athletic Performance & Recovery Lab Panel
  • Longevity & Healthy Aging Lab Panel

FAQ: Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel

What is the Stress, Cortisol, Sleep & Burnout Comprehensive Lab Panel?

The Stress, Cortisol, Sleep & Burnout Comprehensive Lab Panel is a broad blood and urine test panel that includes 46 tests and 153 biomarkers to evaluate stress-response hormones, cortisol context, thyroid function, sex hormones, blood sugar, inflammation, iron status, nutrients, methylation, mitochondrial recovery, cardiometabolic risk, kidney and urine health, liver function, mineral balance, and metabolic stress.

Does this panel diagnose burnout?

No. Burnout is not diagnosed by a single lab panel. This panel provides biomarker context that may support provider-guided review of fatigue, stress, sleep disruption, poor recovery, and related wellness patterns.

Does this panel diagnose adrenal fatigue, adrenal insufficiency, or Cushing syndrome?

No. This panel does not diagnose adrenal fatigue, adrenal insufficiency, or Cushing syndrome. Suspected adrenal insufficiency or Cushing syndrome requires specific medical evaluation and confirmatory testing.

Why are ACTH and cortisol included?

ACTH and cortisol provide pituitary-adrenal signaling and morning stress-response context. They may help support provider-guided review of stress physiology, fatigue, and cortisol patterns.

Why are sex hormones included?

Estradiol, progesterone, testosterone, FSH/LH, and prolactin may provide context for sleep, mood, body composition, libido, perimenopause/menopause, and life-stage hormone patterns.

Why are thyroid markers included?

Thyroid function and thyroid autoimmunity can overlap with fatigue, poor sleep, mood changes, weight changes, temperature sensitivity, hair changes, and low energy.

Why are iron, ferritin, B12, folate, MMA, B6, magnesium, zinc, selenium, and vitamin D included?

These markers may provide context for fatigue, low stamina, mood, nerve function, muscle function, sleep quality, methylation, recovery, and nutrient status.

Why are CoQ10 and OMEGACHECK™ included?

CoQ10 supports mitochondrial energy context, while OMEGACHECK™ evaluates omega fatty acid status for inflammation balance, brain health, mood, recovery, and cardiometabolic wellness.

Does this panel diagnose sleep apnea?

No. Sleep apnea is diagnosed through sleep testing, not routine blood biomarkers. This panel may support fatigue and sleep-related biomarker review, but it does not replace sleep apnea testing.

Should I choose Essential, Advanced, or Comprehensive?

Choose Essential for a focused stress, fatigue, thyroid, blood sugar, iron, inflammation, and nutrient baseline. Choose Advanced for deeper adrenal, thyroid, methylation, kidney, liver, mineral, and recovery review. Choose Comprehensive for the broadest stress, cortisol, sleep, hormone, nutrient, metabolic, inflammation, kidney, liver, and recovery biomarker review.


Important Note

This panel is designed to help evaluate selected biomarkers related to stress physiology, cortisol patterns, sleep-related wellness, burnout-related fatigue, thyroid function, hormones, blood sugar stability, inflammation, iron status, nutrient status, methylation, mitochondrial recovery, cardiometabolic risk, kidney and urine health, liver function, mineral balance, and metabolic stress. It is not intended to diagnose, treat, cure, or prevent disease by itself.

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