Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel
The Stress, Cortisol, Sleep & Burnout Comprehensive Lab Panel includes 46 tests and 153 biomarkers to support broad review of stress hormones, cortisol patterns, fatigue, poor sleep, burnout-related wellness, thyroid function, sex hormones, blood sugar stability, inflammation, iron status, nutrients, methylation, mitochondrial recovery, cardiometabolic risk, kidney and urine health, liver function, mineral balance, and metabolic stress.
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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
Also known as: ACTH, ACTH Plasma, Adrenocorticotropic Hormone, Corticotropin, Cosyntropin
Acth, Plasma
Also known as: Microalbumin Random Urine with Creatinine
Creatinine, Random Urine
Microalbumin
Microalbumin/Creatinine
Also known as: ANA, ANA Screen IFA with Reflex to Titer and Pattern IFA, ANA with Reflux
ANA Screen, IFA
Apolipoprotein B
Also known as: Bilirubin Fractionated
Bilirubin, Direct
Bilirubin, Indirect
Bilirubin, Total
Also known as: C-Reactive Protein, CReactive Protein CRP, CRP
C-REACTIVE PROTEIN
Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)
NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.
Absolute Band Neutrophils (Only Reported If Detected)
Absolute Basophils
Absolute Blasts (Only Reported If Detected)
Absolute Eosinophils
Absolute Lymphocytes
Absolute Metamyelocytes (Only Reported If Detected)
Absolute Monocytes
Absolute Myelocytes (Only Reported If Detected)
Absolute Neutrophils
Absolute Nucleated Rbc (Only Reported If Detected)
Absolute Promyelocytes (Only Reported If Detected)
Band Neutrophils (Only Reported If Detected)
Basophils
Blasts (Only Reported If Detected)
Eosinophils
Hematocrit
Hemoglobin
Lymphocytes
MCH
MCHC
MCV
Metamyelocytes (Only Reported If Detected)
Monocytes
MPV
Myelocytes (Only Reported If Detected)
Neutrophils
Nucleated Rbc (Only Reported If Detected)
Platelet Count
Promyelocytes (Only Reported If Detected)
RDW
Reactive Lymphocytes (Only Reported If Detected)
Red Blood Cell Count
White Blood Cell Count
Also known as: Copper Oxide, Wilson's Disease
Ceruloplasmin
Also known as: CoQ10
Coenzyme Q10
Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20
Albumin
Albumin/Globulin Ratio
Alkaline Phosphatase
Alt
AST
Bilirubin, Total
Bun/Creatinine Ratio
Calcium
Carbon Dioxide
Chloride
Creatinine
Egfr African American
Egfr Non-Afr. American
GFR-AFRICAN AMERICAN
GFR-NON AFRICAN AMERICAN
Globulin
Glucose
Potassium
Protein, Total
Sodium
Urea Nitrogen (Bun)
Copper
Also known as: Cortisol AM
Cortisol, A.M.
CYSTATIN C
eGFR
Also known as: Dehydroepiandrosterone Sulfate, DHEA SO4, DHEA Sulfate Immunoassay, DHEAS, Transdehydroandrosterone
DHEA SULFATE
Estradiol
Ferritin
Also known as: Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH), Follicle Stimulating Hormone and Luteinizing Hormone
Fsh
Lh
Also known as: Gamma Glutamyl Transferase GGT, Gamma-Glutamyl Transferase, Gamma-Glutamyl Transpeptidase, Gamma-GT, GGTP, GTP
Ggt
Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c
HEMOGLOBIN A1C
Also known as: Homocysteine, Homocysteine Cardiovascular
HOMOCYSTEINE,
Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP
Hs Crp
Also known as: Insulin (fasting)
Insulin
Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC
% Saturation
Iron Binding Capacity
Iron, Total
Also known as: Lipid Panel with Ratios (fasting), Lipid Profile with Ratios (fasting), Lipids
Chol/HDLC Ratio
Cholesterol, Total
HDL Cholesterol
LDL-Cholesterol
LDL/HDL Ratio
Non HDL Cholesterol
Triglycerides
Magnesium
Also known as: Magnesium RBC
Magnesium, Rbc
Methylmalonic Acid
ARACHIDONIC ACID
ARACHIDONIC ACID/EPA
DHA
DPA
EPA
EPA+DPA+DHA
LINOLEIC ACID
OMEGA-3 TOTAL
OMEGA-6 TOTAL
OMEGA-6/OMEGA-3 RATIO
Also known as: Inorganic Phosphate, P, Phosphate as Phosphorus, Phosphorus, PO4
Phosphate (As Phosphorus)
Also known as: Pregnenolone LCMSMS
Pregnenolone, LC/MS/MS
Also known as: Progesterone Immunoassay
Progesterone
Also known as: PRL
Prolactin
Also known as: "Biointact" PTH, Intact PTH, Parathyroid Hormone , Parathyroid Hormone (PTH), PTH, PTH Intact without Calcium
PARATHYROID HORMONE,
Vitamin D, 25-Oh, D2
Vitamin D, 25-Oh, D3
Vitamin D, 25-Oh, Total
Also known as: ESR, SED RATE, Sed Rate by Modified Westergren ESR
Sed Rate By Modified
Selenium
Also known as: Free T3, FT3, T3 Free
T3, Free
Also known as: Free T4, FT4, T4 Free
T4, Free
Also known as: Testosterone Total And Free And Sex Hormone Binding Globulin
Free Testosterone
Sex Hormone Binding
TESTOSTERONE, TOTAL,
Thyroglobulin Antibodies
Thyroid Peroxidase
Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test
TSH
Also known as: Serum Urate, UA
Uric Acid
Also known as: UA, with Reflex to Culture, Urinalysis Complete with Reflex to Culture, Urine Analysis, with Reflex to Culture
Amorphous Sediment (Only Reported If Detected)
Appearance
Bacteria
Bilirubin
Calcium Oxalate Crystals (Only Reported If Detected)
Casts (Only Reported If Detected)
Color
Crystals (Only Reported If Detected)
Glucose
Granular Cast (Only Reported If Detected)
Hyaline Cast
Ketones
Leukocyte Esterase
Nitrite
Occult Blood
Ph
Protein
Rbc
Reducing Substances (Only Reported If Detected)
Renal Epithelial Cells (Only Reported If Detected)
Specific Gravity
Squamous Epithelial Cells
Transitional Epithelial (Only Reported If Detected)
Triple Phosphate Crystals (Only Reported If Detected)
Uric Acid Crystals (Only Reported If Detected)
WBC
YEAST (Only Reported If Detected)
Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid
Folate, Serum
Vitamin B12
Also known as: B6, B6 Vitamin, Pyridoxal, Pyridoxal Phosphate, Pyridoxal Phosphate (PLP), Vitamin B6 Pyridoxal Phosphate
Vitamin B6
Also known as: ZN, Plasma
Zinc
The Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel panel contains 46 tests with 153 biomarkers .
Overview
The Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel is designed for people who want a broad lab-based review of biomarkers related to stress-response hormones, cortisol patterns, fatigue, poor sleep, burnout-related wellness, thyroid function, sex hormone balance, blood sugar stability, inflammation, iron status, nutrient status, methylation, mitochondrial recovery, cardiometabolic risk, kidney and urine health, liver function, mineral balance, and metabolic stress.
This panel includes 46 tests and 153 biomarkers to support provider-guided conversations about stress physiology, low energy, poor recovery, sleep disruption, mood changes, cravings, energy crashes, hormone patterns, thyroid overlap, nutrient deficiencies, and metabolic resilience.
This panel does not diagnose burnout, adrenal insufficiency, Cushing syndrome, insomnia, sleep apnea, thyroid disease, hormone imbalance, depression, anxiety, or any medical condition by itself. Suspected adrenal insufficiency and Cushing syndrome require specific clinical evaluation and confirmatory testing, and suspected sleep apnea is evaluated with sleep testing such as polysomnography or home sleep apnea testing.
Why Order This Panel?
The Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel may be helpful for people who want more than a basic cortisol or fatigue test and want a broader look at body systems that may influence stress resilience, sleep quality, recovery, energy, mood, and metabolic balance.
This panel may help provide insight into:
- ACTH and morning cortisol patterns
- DHEA-S and pregnenolone stress-hormone pathway context
- Thyroid function and thyroid autoimmunity
- Sex hormone and life-stage hormone patterns
- Blood sugar, insulin, and A1c patterns
- Inflammation with CRP, hs-CRP, and ESR
- Iron storage and iron availability
- Vitamin D, B12, folate, MMA, B6, magnesium, zinc, selenium, copper, and ceruloplasmin status
- CoQ10 and omega fatty acid status
- Cholesterol, ApoB, and cardiometabolic risk patterns
- Kidney filtration, urine albumin, urinalysis, and urine reflex culture context
- Liver and bile-flow markers
- Bone-mineral and phosphorus patterns
- Uric acid and metabolic stress
This Panel May Be Helpful For People With
- Chronic stress or burnout-like symptoms
- Poor sleep or non-restorative sleep
- Fatigue or low energy
- Brain fog or poor focus
- Energy crashes
- Sugar cravings or stress eating
- Poor recovery after exercise or illness
- Mood changes
- Low motivation
- Weight changes or belly fat
- Low stamina
- Hormone-related sleep or mood concerns
- Thyroid symptoms
- Inflammation concerns
- Low iron or ferritin concerns
- Vitamin D, B12, magnesium, zinc, selenium, or B6 concerns
- Interest in a broad stress, sleep, fatigue, and recovery biomarker review
Which Tier Is Right for Me?
Essential Lab Panel
The Stress, Cortisol, Sleep & Burnout - Essential Lab Panel is best for people who want a focused first-step review of cortisol, fatigue, thyroid function, blood sugar, inflammation, iron status, vitamin D, B12/folate, magnesium, CMP, CBC, and uric acid.
Choose Essential if you want an accessible baseline for stress-related fatigue, poor sleep, blood sugar stability, thyroid overlap, inflammation, iron status, and nutrient support.
Advanced Lab Panel
The Stress, Cortisol, Sleep & Burnout - Advanced Lab Panel is best for people who want deeper insight into ACTH, DHEA-S, pregnenolone, Free T3, thyroid antibodies, methylation, RBC magnesium, CoQ10, ApoB, kidney/urine markers, liver/bile markers, mineral balance, PTH/phosphate, and ESR.
Choose Advanced if symptoms are persistent or if you want broader review of stress-response hormones, thyroid overlap, methylation, nutrient status, kidney/urine health, liver function, inflammation, and recovery.
Comprehensive Lab Panel
The Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel is the broadest option. It includes 46 tests and 153 biomarkers and adds premium markers for sex hormones, life-stage hormones, prolactin, copper/ceruloplasmin, OMEGACHECK™, ANA screening, and full-system stress, sleep, burnout, and recovery review.
Choose Comprehensive if you want the widest review of stress hormones, cortisol patterns, sleep/fatigue overlap, thyroid function, sex hormones, inflammation, iron status, nutrients, methylation, mitochondrial recovery, metabolic stress, kidney/urine health, liver function, omega status, and hormone/life-stage patterns.
Tests Included and Why They Matter
Stress Hormones and HPA-Axis Context
ACTH, Plasma
ACTH is a pituitary hormone that signals the adrenal glands to produce cortisol.
This test is included because ACTH can provide pituitary-adrenal signaling context when reviewed with morning cortisol. It may help support provider-guided discussion of stress-response patterns, fatigue, low resilience, and adrenal-axis context.
Cortisol, A.M.
Morning cortisol provides a snapshot of cortisol during the time of day when cortisol is typically expected to be higher.
This test is included because cortisol is central to stress-response physiology, sleep-wake rhythm, energy, blood sugar patterns, and resilience. It should be interpreted with ACTH, symptoms, medications, sleep timing, and provider guidance.
DHEA Sulfate, Immunoassay
DHEA-S is an adrenal androgen marker.
This test is included because DHEA-S may provide context for adrenal hormone patterns, stress physiology, energy, aging-related hormone changes, DHEA supplementation, and resilience-related wellness.
Pregnenolone, LC/MS/MS
Pregnenolone is a steroid hormone precursor.
This test is included because it may provide premium context for steroid hormone pathways, adrenal hormone production, stress physiology, and hormone balance. It should be interpreted with cortisol, DHEA-S, sex hormones, symptoms, and provider guidance.
Sleep, Mood and Life-Stage Hormone Context
Estradiol
Estradiol is a major estrogen hormone.
This test is included because estradiol may provide context for sleep quality, mood, temperature regulation, cycle or menopause-related symptoms, bone health, and hormone balance. Interpretation differs by sex, age, cycle timing, menopause status, and hormone therapy use.
Progesterone, Immunoassay
Progesterone is a reproductive hormone that varies by sex, menstrual cycle timing, pregnancy status, menopause status, and hormone therapy use.
This test is included because progesterone may provide context for sleep, mood, cycle timing, perimenopause/menopause discussions, and hormone-balance review.
Testosterone, Total and Free and Sex Hormone Binding Globulin
This test evaluates total testosterone, free testosterone, and SHBG.
It is included because testosterone availability may provide context for energy, libido, mood, muscle mass, body composition, recovery, motivation, and sleep-related wellness discussions. Interpretation differs by sex, age, symptoms, and hormone therapy use.
FSH and LH
FSH and LH are pituitary hormones involved in reproductive hormone signaling.
These tests are included because they may provide life-stage and hormone-axis context, especially when stress, sleep, fatigue, cycle changes, menopause transition, low testosterone patterns, or reproductive hormone symptoms are part of the discussion.
Prolactin
Prolactin is a pituitary hormone that can affect reproductive hormone signaling.
This test is included because prolactin may provide context for libido changes, menstrual changes, testosterone patterns, pituitary-related hormone patterns, and broader hormone/sleep overlap.
Thyroid, Energy and Autoimmune Thyroid Context
TSH
TSH is a key thyroid screening marker.
This test is included because thyroid patterns can overlap with fatigue, poor sleep, low mood, weight changes, cold intolerance, heat intolerance, brain fog, and low energy.
T4, Free
Free T4 measures available thyroxine, a major thyroid hormone.
This test is included because it adds thyroid hormone production context beyond TSH alone and may help clarify thyroid patterns when fatigue, metabolism, sleep, or energy symptoms are present.
T3, Free
Free T3 measures available active thyroid hormone.
This test is included because Free T3 may provide context for energy output, metabolism, body temperature, fatigue, and recovery.
Thyroid Peroxidase and Thyroglobulin Antibodies
These antibodies help evaluate autoimmune thyroid patterns.
This test is included because autoimmune thyroid activity may overlap with fatigue, poor sleep, mood changes, weight changes, hair changes, and other thyroid-related concerns.
Blood Sugar, Metabolic and Cardiovascular Stress
Comprehensive Metabolic Panel, CMP
The CMP evaluates glucose, liver enzymes, kidney markers, electrolytes, calcium, albumin, total protein, and other metabolic markers.
This test is included because stress, fatigue, poor sleep, and burnout-like symptoms benefit from a broad organ-function baseline. CMP provides context for glucose, liver function, kidney function, hydration, electrolytes, calcium, albumin, and protein status.
Hemoglobin A1c
Hemoglobin A1c reflects longer-term blood sugar patterns.
This test is included because blood sugar regulation may overlap with energy crashes, cravings, poor sleep, fatigue, and metabolic stress.
Insulin
Insulin helps move glucose from the bloodstream into cells.
This test is included because fasting insulin may provide insulin-resistance context when symptoms include cravings, belly fat, energy crashes, fatigue, or stress eating.
Lipid Panel with Ratios
The Lipid Panel with Ratios evaluates cholesterol, triglycerides, HDL, LDL, and cholesterol ratios.
This test is included because poor sleep, stress, thyroid patterns, insulin resistance, and weight changes can overlap with cardiometabolic risk.
Apolipoprotein B
ApoB reflects the number of atherogenic cholesterol-carrying particles.
This test is included because ApoB may provide deeper cardiometabolic risk context than LDL cholesterol alone.
Uric Acid
Uric acid is a metabolic waste product.
This test is included because uric acid may provide context for metabolic stress, gout risk, kidney stone risk, blood pressure, kidney function, and cardiometabolic wellness.
Inflammation and Immune Context
C-Reactive Protein, CRP
CRP is a blood marker that can rise when inflammation is present.
This test is included because inflammation may overlap with fatigue, poor recovery, metabolic stress, sleep disruption, and general wellness. CRP does not identify the cause of inflammation by itself and should be interpreted with symptoms and other findings.
hs-CRP
High-sensitivity C-reactive protein is a more sensitive inflammation marker often used for low-grade inflammation and cardiometabolic context.
This test is included because low-grade inflammation may overlap with stress, fatigue, poor sleep, metabolic risk, and recovery.
Sed Rate by Modified Westergren, ESR
ESR is a broad inflammation marker.
This test is included because it adds systemic inflammation context that may complement CRP and hs-CRP.
ANA Screen, IFA with Reflex to Titer and Pattern, IFA
ANA testing evaluates antinuclear antibody patterns and may reflex to titer and pattern when criteria are met.
This test is included because autoimmune overlap may be relevant when fatigue coexists with joint pain, rashes, dry eyes, dry mouth, or autoimmune family history. Positive ANA results can occur without autoimmune disease and should be interpreted with symptoms, exam findings, and provider guidance.
Reflex Test Notice: If reflex testing is performed, additional charges may apply.
Iron, Oxygen Delivery and Fatigue
CBC, includes Differential and Platelets
The CBC evaluates red blood cells, white blood cells, hemoglobin, hematocrit, platelets, and white blood cell types.
This test is included because blood count patterns may provide context for anemia, infection clues, immune activity, platelet changes, fatigue, and overall blood health.
Ferritin
Ferritin measures stored iron.
This test is included because ferritin may provide context for fatigue, low stamina, hair shedding, restless sleep-type concerns, inflammation, and iron storage.
Iron and Total Iron Binding Capacity, TIBC
Iron and TIBC help evaluate circulating iron and iron transport capacity.
This test is included because iron availability can provide context for oxygen delivery, fatigue, low stamina, anemia patterns, and ferritin interpretation.
Nutrients, Methylation and Recovery
QuestAssureD™ 25-Hydroxyvitamin D, D2, D3, LC/MS/MS
Vitamin D testing measures vitamin D status.
This test is included because vitamin D supports immune, bone, muscle, mood, inflammation, and calcium-balance pathways.
Vitamin B12 and Folate Panel, Serum
This panel measures vitamin B12 and folate.
B12 and folate support red blood cell production, nerve function, DNA synthesis, methylation, cognition, mood, and energy.
Methylmalonic Acid
Methylmalonic acid, or MMA, is a functional marker related to vitamin B12 status.
This test is included because MMA can provide deeper B12 interpretation when serum B12 is borderline or symptoms suggest B12-related concerns.
Homocysteine
Homocysteine is influenced by B12, folate, vitamin B6, methylation pathways, kidney function, and vascular health.
This test is included because it provides B-vitamin, methylation, vascular, cognitive, and stress-related wellness context.
Vitamin B6, Pyridoxal Phosphate
Vitamin B6 supports neurotransmitter pathways, methylation, amino acid metabolism, immune function, and energy metabolism.
This test is included because B6 may provide context for mood, energy, nerve function, and homocysteine interpretation.
Magnesium
Magnesium supports muscle function, nerve signaling, sleep, glucose metabolism, blood pressure regulation, and energy production.
This test is included because magnesium may provide sleep, stress, cramps, fatigue, recovery, and metabolic context.
Magnesium, RBC
RBC magnesium may provide deeper magnesium status context.
This test is included because deeper magnesium evaluation may be useful when sleep disruption, fatigue, cramps, stress symptoms, or muscle symptoms are present.
Zinc
Zinc supports immune function, hormone pathways, neurotransmitter pathways, thyroid support, wound healing, and recovery.
This test is included because zinc may provide immune, nervous system, recovery, and stress-related wellness context.
Selenium
Selenium supports thyroid-related pathways and antioxidant systems.
This test is included because selenium may provide thyroid, antioxidant, and recovery context.
Copper
Copper supports iron metabolism, connective tissue, antioxidant enzyme systems, neurologic function, and cellular function.
This test is included because copper may provide mineral-balance context, especially when zinc and iron markers are included.
Ceruloplasmin
Ceruloplasmin is a copper-carrying protein.
This test is included because it helps interpret copper status and supports mineral balance review.
Coenzyme Q10
CoQ10 supports mitochondrial energy production and antioxidant function.
This test is included because CoQ10 may provide context for fatigue, muscle symptoms, statin-associated muscle complaints, mitochondrial energy, and recovery.
OMEGACHECK™
OMEGACHECK™ evaluates omega fatty acid status.
This test is included because omega fatty acid patterns may provide context for inflammation balance, mood, brain health, recovery, and cardiometabolic wellness.
Kidney, Urine, Liver and Mineral Balance
Cystatin C with eGFR
Cystatin C with eGFR provides kidney filtration context beyond creatinine alone.
This test is included because kidney function may be relevant to medication/supplement safety, cardiometabolic risk, fatigue, and metabolic stress.
Albumin, Random Urine with Creatinine
This urine test evaluates albumin relative to creatinine.
It is included because urine albumin may provide kidney and vascular risk context, especially with insulin resistance, blood pressure, metabolic stress, or long-term wellness monitoring.
Urinalysis, Complete, with Reflex to Culture
A complete urinalysis evaluates urine markers such as protein, blood, glucose, ketones, specific gravity, pH, and other findings. If certain findings meet laboratory criteria, a urine culture may be performed.
This test is included because urine findings may provide hydration, kidney, glucose, ketone, protein, blood, and urine-health context.
Reflex Test Notice: If reflex urine culture is performed, additional charges may apply.
Gamma Glutamyl Transferase, GGT
GGT is a liver and bile duct enzyme.
This test is included because it may provide liver, bile-flow, alcohol, medication, supplement, fatty liver, and metabolic context.
Bilirubin, Fractionated
Bilirubin, Fractionated measures total, direct, and indirect bilirubin.
This test is included because bilirubin patterns may provide liver processing and bile-flow context beyond standard liver enzymes.
Phosphate, as Phosphorus
Phosphorus supports bone-mineral balance, ATP/energy pathways, kidney function, and vitamin D regulation.
This test is included because it adds mineral, energy, kidney, and bone-related context.
PTH, Intact without Calcium
PTH helps regulate calcium and phosphorus balance.
This test is included because PTH may provide parathyroid, vitamin D, calcium, phosphorus, bone-mineral, and fatigue-related mineral context. If available, PTH, Intact and Calcium may be preferable for paired interpretation.
Professional Reflex Testing Notice
This panel includes ANA Screen, IFA with Reflex to Titer and Pattern, IFA and Urinalysis, Complete, with Reflex to Culture. Reflex testing means the laboratory may automatically perform additional testing when initial findings meet specific criteria.
If reflex testing or urine culture is performed, additional charges may apply. Reflex results should be reviewed with a licensed healthcare provider.
Related Biomarker Patterns This Panel May Help Identify
This panel may help identify or support provider-guided review of:
- ACTH and morning cortisol patterns
- DHEA-S and pregnenolone patterns
- Estradiol, progesterone, testosterone, FSH/LH, and prolactin patterns
- TSH, Free T4, Free T3, and thyroid antibody patterns
- A1c, insulin, glucose, and metabolic stress patterns
- hs-CRP, CRP, ESR, and ANA screening patterns
- Ferritin, iron, and TIBC patterns
- Vitamin D, B12, folate, MMA, homocysteine, B6, magnesium, RBC magnesium, zinc, selenium, copper, and ceruloplasmin status
- CoQ10 and omega fatty acid patterns
- ApoB, lipid ratios, and cardiometabolic risk patterns
- Cystatin C, urine albumin, urinalysis, GGT, bilirubin, phosphate, and PTH patterns
Professional Safety and Interpretation Notice
This panel is designed to support stress, cortisol, sleep, and burnout-related biomarker review. It does not diagnose burnout, adrenal insufficiency, Cushing syndrome, insomnia, sleep apnea, thyroid disease, hormone imbalance, depression, anxiety, kidney disease, liver disease, or nutrient deficiency by itself.
Results should be interpreted with a licensed healthcare provider and reviewed alongside symptoms, sleep patterns, medications, supplements, hormone therapy, thyroid medication use, menstrual cycle timing, menopause status, stress level, nutrition, exercise, alcohol use, medical history, and family history.
Do not stop or change medications, hormones, thyroid medication, cortisol-related treatment, or supplements without guidance from your healthcare provider.
How to Prepare for This Panel
Preparation may vary depending on the specific tests and lab instructions. In general:
- Morning collection may be important for ACTH, cortisol, testosterone, and some hormones.
- Fasting may be recommended because glucose, insulin, lipid, and metabolic markers are included.
- Bring a list of medications, supplements, hormones, thyroid medications, sleep aids, steroids, adrenal supplements, biotin, and doses.
- Ask your provider whether biotin should be paused before thyroid or hormone testing.
- Note symptoms such as fatigue, poor sleep, stress, brain fog, mood changes, cravings, energy crashes, hair changes, weight changes, low libido, or poor recovery.
- Follow all collection instructions provided with your order.
What Happens After You Receive Your Results?
After results are available, biomarkers can be organized into key categories: stress-response hormones, cortisol patterns, thyroid function, sex hormones, blood sugar stability, inflammation, iron status, nutrients, methylation, mitochondrial recovery, cardiometabolic risk, kidney/urine health, liver function, mineral balance, and metabolic stress.
During a provider review, you can discuss whether results suggest follow-up testing, sleep evaluation, medication review, hormone timing review, thyroid review, nutrition changes, supplement review, exercise recovery adjustments, stress management planning, or additional clinical evaluation.
Additional Panels to Consider
Customers interested in the Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel may also consider:
- Stress, Cortisol, Sleep & Burnout - Essential Lab Panel
- Stress, Cortisol, Sleep & Burnout - Advanced Lab Panel
- Fatigue, Low Energy & Brain Fog Lab Panel
- Thyroid & Metabolism Lab Panel
- Men’s Testosterone, Energy & Vitality Lab Panel
- Women’s Hormone Balance & Perimenopause Lab Panel
- Prediabetes & Insulin Resistance Lab Panel
- Vitamin, Mineral & Nutrient Deficiency Lab Panel
- Athletic Performance & Recovery Lab Panel
- Longevity & Healthy Aging Lab Panel
FAQ: Stress, Cortisol, Sleep & Burnout - Comprehensive Lab Panel
What is the Stress, Cortisol, Sleep & Burnout Comprehensive Lab Panel?
The Stress, Cortisol, Sleep & Burnout Comprehensive Lab Panel is a broad blood and urine test panel that includes 46 tests and 153 biomarkers to evaluate stress-response hormones, cortisol context, thyroid function, sex hormones, blood sugar, inflammation, iron status, nutrients, methylation, mitochondrial recovery, cardiometabolic risk, kidney and urine health, liver function, mineral balance, and metabolic stress.
Does this panel diagnose burnout?
No. Burnout is not diagnosed by a single lab panel. This panel provides biomarker context that may support provider-guided review of fatigue, stress, sleep disruption, poor recovery, and related wellness patterns.
Does this panel diagnose adrenal fatigue, adrenal insufficiency, or Cushing syndrome?
No. This panel does not diagnose adrenal fatigue, adrenal insufficiency, or Cushing syndrome. Suspected adrenal insufficiency or Cushing syndrome requires specific medical evaluation and confirmatory testing.
Why are ACTH and cortisol included?
ACTH and cortisol provide pituitary-adrenal signaling and morning stress-response context. They may help support provider-guided review of stress physiology, fatigue, and cortisol patterns.
Why are sex hormones included?
Estradiol, progesterone, testosterone, FSH/LH, and prolactin may provide context for sleep, mood, body composition, libido, perimenopause/menopause, and life-stage hormone patterns.
Why are thyroid markers included?
Thyroid function and thyroid autoimmunity can overlap with fatigue, poor sleep, mood changes, weight changes, temperature sensitivity, hair changes, and low energy.
Why are iron, ferritin, B12, folate, MMA, B6, magnesium, zinc, selenium, and vitamin D included?
These markers may provide context for fatigue, low stamina, mood, nerve function, muscle function, sleep quality, methylation, recovery, and nutrient status.
Why are CoQ10 and OMEGACHECK™ included?
CoQ10 supports mitochondrial energy context, while OMEGACHECK™ evaluates omega fatty acid status for inflammation balance, brain health, mood, recovery, and cardiometabolic wellness.
Does this panel diagnose sleep apnea?
No. Sleep apnea is diagnosed through sleep testing, not routine blood biomarkers. This panel may support fatigue and sleep-related biomarker review, but it does not replace sleep apnea testing.
Should I choose Essential, Advanced, or Comprehensive?
Choose Essential for a focused stress, fatigue, thyroid, blood sugar, iron, inflammation, and nutrient baseline. Choose Advanced for deeper adrenal, thyroid, methylation, kidney, liver, mineral, and recovery review. Choose Comprehensive for the broadest stress, cortisol, sleep, hormone, nutrient, metabolic, inflammation, kidney, liver, and recovery biomarker review.
Important Note
This panel is designed to help evaluate selected biomarkers related to stress physiology, cortisol patterns, sleep-related wellness, burnout-related fatigue, thyroid function, hormones, blood sugar stability, inflammation, iron status, nutrient status, methylation, mitochondrial recovery, cardiometabolic risk, kidney and urine health, liver function, mineral balance, and metabolic stress. It is not intended to diagnose, treat, cure, or prevent disease by itself.