Soluble Liver Antigen (SLA) Autoantibody

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Soluble Liver Antigen Sla Autoantibody

Soluble Liver Antigen

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The Soluble Liver Antigen (SLA) Autoantibody test contains 1 test with 1 biomarker.

Clinical Significance

Soluble Liver Antigen (SLA) Autoantibody - Anti-soluble liver antigen antibodies are detected in 10-30% of patients with type 1 autoimmune hepatitis (AIH), but not in patients with type 2 AIH, primary sclerosing cholangitis or primary biliary cirrhosis. The antibody is directed against a UGA suppressor tRNA-associated protein. In some patients with AIH, this antibody may be the only autoantibody detected by current assays.


Immunoassay (IA)

Reference Range(s)

<20.1 U Negative
20.1-24.9 U Equivocal
≥25.0 U


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