Prostaglandin E2, Serum/Plasma (PG-E2)

The Prostaglandin E2, Serum/Plasma (PG-E2) test contains 1 test.

Clinical Significance

Prostaglandins are synthesized from arachidonic acid by cyclooxygenase (COX)-1 or -2, which converts the acid into PGH2. This is further processed by cytosolic or microsomal prostaglandin synthesis to become prostaglandin E2. PG E2 is produced in many tissues and the level is increased during inflammation, arthritis, fever, endometriosis, tissue injury, pheochromocytoma, VIP producing tumors and variety of cancers with amine peptide productions. Prostaglandin E2 production and circulating levels are reduced by aspiring and indomethacin treatment.

Alternative Name(s)


The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

*Process times are an estimate and are not guaranteed. The lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

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