Oxidative Stress & Inflammation Panel — Comprehensive

The Oxidative Stress & Inflammation Panel — Comprehensive evaluates key biomarkers linked to systemic inflammation and oxidative balance. By measuring hs-CRP, ESR, GGT, LDH, iron status, albumin, bilirubin, uric acid, zinc, and copper, this panel provides a detailed view of inflammatory activity, cellular stress, and antioxidant-related pathways to support informed health evaluation.

Serum, Plasma-Unspecified Vial Pour, Blood
Phlebotomist

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: ALB, Albumin ALB

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Also known as: Bilirubin Total, TBIL, Total bilirubin

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Copper

Ferritin

Ferritin is a protein found inside cells that stores iron so your body can use it later. A ferritin test indirectly measures the amount of iron in your blood. The amount of ferritin in your blood (serum ferritin level) is directly related to the amount of iron stored in your body.

Also known as: Gamma Glutamyl Transferase GGT, Gamma-Glutamyl Transferase, Gamma-Glutamyl Transpeptidase, Gamma-GT, GGTP, GTP

Ggt

Gamma-glutamyl transpeptidase (GGT) is a test to measure the amount of the enzyme GGT in the blood.

Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP

Hs Crp

A high-sensitivity CRP (hs-CRP) test may be used by itself, in combination with other cardiac risk markers, or in combination with a lipoprotein-associated phospholipase A2 (Lp-PLA2) test that evaluates vascular inflammation. The hs-CRP test accurately detects low concentrations of C-reactive protein to help predict a healthy person's risk of cardiovascular disease (CVD). High-sensitivity CRP is promoted by some as a test for determining a person's risk level for CVD, heart attacks, and strokes. The current thinking is that hs-CRP can play a role in the evaluation process before a person develops one of these health problems.

Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC

% Saturation

Iron Binding Capacity

Total iron binding capacity (TIBC) is a blood test to see if you may have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.

Iron, Total

Iron is a mineral that our bodies need for many functions. For example, iron is part of hemoglobin, a protein which carries oxygen from our lungs throughout our bodies. It helps our muscles store and use oxygen. Iron is also part of many other proteins and enzymes. Your body needs the right amount of iron. If you have too little iron, you may develop iron deficiency anemia. Causes of low iron levels include blood loss, poor diet, or an inability to absorb enough iron from foods. People at higher risk of having too little iron are young children and women who are pregnant or have periods.

Also known as: Lactate Dehydrogenase LD, LDH

Ld

LDH isoenzymes is a test to check how much of the different types of lactate dehydrogenase (LDH) are in the blood. Measurement of LDH isoenzymes helps determine the location of any tissue damage. LDH is found in many body tissues such as the heart, liver, kidney, skeletal muscle, brain, blood cells, and lungs. LDH exists in 5 forms, which differ slightly in structure. LDH-1 is found primarily in heart muscle and red blood cells. LDH-2 is concentrated in white blood cells. LDH-3 is highest in the lung. LDH-4 is highest in the kidney, placenta, and pancreas. LDH-5 is highest in the liver and skeletal muscle.

Also known as: ESR, SED RATE, Sed Rate by Modified Westergren ESR

Sed Rate By Modified

Erythrocyte sedimentation rate (ESR) is an indirect measure of the degree of inflammation present in the body. It actually measures the rate of fall (sedimentation) of erythrocytes (red blood cells) in a sample of blood.

Also known as: Serum Urate, UA

Uric Acid

Uric acid is a chemical created when the body breaks down substances called purines. Purines are found in some foods and drinks. These include liver, anchovies, mackerel, dried beans and peas, and beer. Most uric acid dissolves in blood and travels to the kidneys. From there, it passes out in urine. If your body produces too much uric acid or doesn't remove enough if it, you can get sick. A high level of uric acid in the blood is called hyperuricemia.

Also known as: ZN, Plasma

Zinc

*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through a national lab. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Oxidative Stress & Inflammation Panel — Comprehensive panel contains 11 tests with 13 biomarkers .

The Oxidative Stress & Inflammation Panel — Comprehensive is a targeted laboratory assessment designed to evaluate biochemical markers associated with systemic inflammation, oxidative stress, cellular turnover, and antioxidant balance. Rather than relying on a single inflammatory marker, this panel integrates proteins, enzymes, iron-related markers, trace minerals, and metabolic byproducts to provide a broader and more nuanced view of inflammatory activity and oxidative burden within the body.

Oxidative stress occurs when reactive oxygen species overwhelm antioxidant defenses, potentially affecting cellular integrity, vascular health, immune signaling, and metabolic efficiency. Inflammation often accompanies or amplifies oxidative processes, creating feedback loops that can influence multiple organ systems. This panel is structured to capture both sides of that relationship by measuring inflammatory markers, oxidative stress–related enzymes, iron metabolism indicators, and key antioxidant-related nutrients such as zinc and copper.

Markers such as high-sensitivity C-reactive protein (hs-CRP) and erythrocyte sedimentation rate (ESR) provide insight into inflammatory activity, while enzymes like gamma glutamyl transferase (GGT) and lactate dehydrogenase (LDH) reflect cellular stress and turnover. Iron status markers and ferritin add context regarding oxidative potential and inflammatory response, while albumin and bilirubin contribute information related to antioxidant capacity and liver-related metabolism.

The Oxidative Stress & Inflammation Panel — Comprehensive is commonly used in preventive health, cardiometabolic risk assessment, integrative care, and longitudinal monitoring when a deeper understanding of inflammatory and oxidative patterns is clinically relevant. Its strength lies in integrating multiple complementary markers to support contextual interpretation rather than isolated conclusions.

When and Why Someone Would Order This Panel

Evaluating Systemic Inflammation

This panel is frequently ordered when individuals or healthcare providers want to assess low-grade or chronic inflammation using multiple complementary markers. While hs-CRP is widely used, pairing it with ESR (sed rate) provides additional perspective on inflammatory patterns and duration.

Assessing Oxidative Stress and Cellular Turnover

Markers such as LDH and GGT can reflect cellular stress, tissue turnover, and oxidative burden. These markers are often evaluated when laboratory trends suggest metabolic strain or when a broader assessment of oxidative processes is desired.

Exploring Iron and Inflammation Interactions

Iron metabolism plays a complex role in both oxidative stress and inflammation. Ferritin, iron, and total iron binding capacity (TIBC) help characterize iron storage and availability while also serving as indirect indicators of inflammatory activity in certain contexts.

Monitoring Cardiometabolic and Vascular Health

Inflammation and oxidative stress are closely linked to cardiovascular and metabolic processes. This panel may be used as part of a broader risk assessment strategy to better understand inflammatory contributors to cardiometabolic health.

Preventive and Integrative Health Monitoring

In preventive and integrative health settings, this panel supports proactive monitoring of inflammatory and oxidative patterns over time. It is commonly used to establish a baseline or to track changes in response to lifestyle, dietary, or clinical interventions.

What Does the Panel Measure

Inflammation Markers

High-sensitivity C-reactive protein (hs-CRP) is a widely recognized marker of low-grade systemic inflammation. Sedimentation rate (ESR) by modified Westergren reflects inflammatory activity by measuring how quickly red blood cells settle, offering complementary insight into inflammatory patterns.

Oxidative Stress and Cellular Enzymes

Gamma glutamyl transferase (GGT) is associated with oxidative stress, glutathione metabolism, and liver-related antioxidant pathways. Lactate dehydrogenase (LDH) reflects cellular turnover and tissue stress, providing insight into metabolic strain.

Iron and Related Markers

Iron, total iron binding capacity (TIBC), and ferritin together evaluate iron availability, transport, and storage. Ferritin, in particular, may rise in inflammatory states, making it useful when interpreted alongside other markers.

Proteins and Metabolic Byproducts

Serum albumin contributes to antioxidant capacity and reflects nutritional and inflammatory status. Total bilirubin functions as an endogenous antioxidant and provides context related to red blood cell turnover and liver metabolism. Uric acid serves as both an antioxidant and a marker associated with oxidative metabolism.

Trace Minerals

Zinc and copper are essential trace minerals involved in antioxidant enzyme systems and immune regulation. Their balance is important, as disproportionate levels may influence oxidative and inflammatory processes.

How Patients and Healthcare Providers Use the Results

Identifying Inflammatory and Oxidative Patterns

Results from this panel help identify patterns of inflammation and oxidative stress by integrating multiple biomarkers. Providers evaluate these markers collectively to understand whether inflammatory activity appears acute, chronic, or metabolically driven.

Supporting Evaluation of Related Conditions

Healthcare providers may reference this panel when evaluating laboratory patterns associated with inflammatory states, oxidative stress–related conditions, cardiometabolic risk, liver-related enzyme trends, or iron-related inflammatory patterns.

Monitoring Trends Over Time

Because inflammation and oxidative stress can fluctuate, repeat testing allows for longitudinal monitoring. Tracking changes over time can help contextualize laboratory trends alongside clinical findings and broader health strategies.

Facilitating Informed Clinical Discussions

The panel provides objective data that supports evidence-based conversations between patients and healthcare providers. It is not intended as a standalone diagnostic tool, but as a structured resource to guide further evaluation, monitoring, or clinical decision-making.

The Oxidative Stress & Inflammation Panel — Comprehensive offers a multifaceted approach to evaluating inflammatory activity and oxidative balance by integrating enzymes, proteins, iron markers, trace minerals, and inflammatory indicators into a single assessment. This comprehensive design reflects the complex interplay between oxidative stress, inflammation, metabolism, and antioxidant defense systems.

By emphasizing context and pattern recognition rather than isolated values, the panel supports thoughtful interpretation and longitudinal monitoring. Whether used in preventive screening, advanced risk assessment, or ongoing health evaluation, it provides reliable laboratory insight that complements clinical judgment and individualized care—without assumptions or transactional framing.

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