Metanephrines, Fractionated, LC/MS/MS, 24-Hour Uri

The Metanephrines, Fractionated, LC/MS/MS, 24-Hour Uri test contains 1 test with 4 biomarkers.

Metanephrines, Fractionated, LC/MS/MS, 24-Hour Urine

Includes: Metanephrine, Normetanephrine, Total Metanephrines

Patient Preparation : It is preferable for the patient to be off medications for three days prior to collection. Patient should avoid tobacco, tea, coffee, for three days prior to specimen collection. Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection.

Preferred Specimen(s) : 5 mL 24-hour urine with 25 mL 6N HCl collected in a 24-hour urine container 

Clinical Significance: Test is useful in the evaluation of pheochromocytoma.