Ulta Lab Tests

Magnesium, Anxiety & Sleep Support Panel

Blood
Blood Draw, Phlebotomist

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Albumin/Globulin Ratio

The ratio of albumin to globulin (A/G ratio) is calculated from measured albumin and calculated globulin (total protein - albumin). Normally, there is a little more albumin than globulins, giving a normal A/G ratio of slightly over 1. Because disease states affect the relative amounts of albumin and globulin, the A/G ratio may provide a clue as to the cause of the change in protein levels. A low A/G ratio may reflect overproduction of globulins, such as seen in multiple myeloma or autoimmune diseases, or underproduction of albumin, such as may occur with cirrhosis, or selective loss of albumin from the circulation, as may occur with kidney disease (nephrotic syndrome). A high A/G ratio suggests underproduction of immunoglobulins as may be seen in some genetic deficiencies and in some leukemias. More specific tests, such as liver enzyme tests and serum protein electrophoresis, must be performed to make an accurate diagnosis. With a low total protein that is due to plasma expansion (dilution of the blood), the A/G ratio will typically be normal because both albumin and globulin will be diluted to the same extent.

Alkaline Phosphatase

Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone.

Alt

Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.

AST

AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bun/Creatinine Ratio

A ratio between a person’s BUN and blood creatinine to help determine what is causing these concentrations to be higher than normal. The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration. It may also be seen with increased protein, from gastrointestinal bleeding, or increased protein in the diet. The ratio may be decreased with liver disease (due to decrease in the formation of urea) and malnutrition.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.

Carbon Dioxide

CO2 is carbon dioxide. Measures the amount of carbon dioxide in the liquid part of your blood, called the serum. In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.

Chloride

Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance. This is a measure of the amount of chloride in the fluid portion (serum) of the blood.

Creatinine

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys work.

Egfr African American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

Egfr Non-Afr. American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

GFR-AFRICAN AMERICAN

GFR-NON AFRICAN AMERICAN

Globulin

Globulins is the collective term for most blood proteins other than albumin. Identifying the types of globulins can help diagnose certain disorders. Globulins are roughly divided into three groups: alpha, beta, and gamma globulins. Gamma globulines include various types of antibodies such as immunoglobulins (Ig) M, G, and A.

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Potassium

Potassium is a mineral that the body needs to work normally. It helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Protein, Total

The total protein is the total amount of two classes of proteins, albumin and globulin that are found in the fluid portion of your blood. Proteins are important parts of all cells and tissues. Your albumin helps prevent fluid from leaking out of blood vessels and your globulins are an important part of your immune system.

Sodium

Sodium is a substance that the body needs to work properly it is vital to normal body processes, including nerve and muscle function

Urea Nitrogen (Bun)

BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down. BUN measures the amount of urea nitrogen in the blood.

Also known as: Cortisol AM

Cortisol, A.M.

A cortisol level is a blood test that measures the amount of cortisol, a steroid hormone produced by the adrenal gland. The test is done to check for increased or decreased cortisol production. Cortisol is a steroid hormone released from the adrenal gland in response to ACTH, a hormone from the pituitary gland in the brain. Cortisol affects many different body systems. It plays a role in: bone, circulatory system, immune system. metabolism of fats, carbohydrates, and protein. ervous system and stress responses.

Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP

Hs Crp

A high-sensitivity CRP (hs-CRP) test may be used by itself, in combination with other cardiac risk markers, or in combination with a lipoprotein-associated phospholipase A2 (Lp-PLA2) test that evaluates vascular inflammation. The hs-CRP test accurately detects low concentrations of C-reactive protein to help predict a healthy person's risk of cardiovascular disease (CVD). High-sensitivity CRP is promoted by some as a test for determining a person's risk level for CVD, heart attacks, and strokes. The current thinking is that hs-CRP can play a role in the evaluation process before a person develops one of these health problems.

Magnesium

ARACHIDONIC ACID

ARACHIDONIC ACID/EPA

DHA

DPA

EPA

EPA+DPA+DHA

LINOLEIC ACID

OMEGA-3 TOTAL

OMEGA-6 TOTAL

OMEGA-6/OMEGA-3 RATIO

Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid

Folate, Serum

Folate is part of the B complex of vitamins and is measures the levels of folate in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Folate is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis.. A deficiency inr folate can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow.

Vitamin B12

Vitamin B12 is part of the B complex of vitamins and measurea the levels of vitamin B12 in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Cobalamine, or vitamin B12, is found in animal products such as red meat, fish, poultry, milk, yogurt, and eggs and is not produced in the human body. In recent years, fortified cereals, breads, and other grain products have also become important dietary sources of B12. Vitamin B12 is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis. B12 is important for nerve health. A deficiency in B12 can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow. B12 deficiency can lead to varying degrees of neuropathy, nerve damage that can cause tingling and numbness in the affected person's hands and feet.

Also known as: ,25-Hydroxyvitamin D2, 25-Hydroxycholecalciferol (25OHD3), 25-OH-D2,D3 Vitamin, D2 Vitamin,25-Hydroxyvitamin D3,25-OH-D3, QuestAssureD 25Hydroxyvitamin D D2 D3 LCMSMS, Vitamin D, Vitamin D, 25-Hydroxy, Vitamin D2, 25-hydroxy,25-Hydroxyergocalciferol (25OHD2),Vitamin D3, 25-hydroxy

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.
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The Magnesium, Anxiety & Sleep Support Panel panel contains 7 tests with 37 biomarkers .

Overview of the Magnesium, Anxiety & Sleep Support Panel

The Magnesium, Anxiety & Sleep Support Panel is a specialized diagnostic tool designed to assess biochemical factors that influence nervous system function, stress response, mood regulation, and restorative sleep. Anxiety and poor sleep quality are often linked to nutritional deficiencies, hormonal imbalances, and systemic inflammation. This panel evaluates key nutrients, stress markers, metabolic indicators, and cardiovascular health factors to identify underlying contributors to these issues.

Magnesium plays a critical role in nerve conduction, muscle relaxation, and neurotransmitter regulation, making it essential for calmness and quality sleep. Deficiencies in magnesium and other nutrients such as vitamin D, B12, and folate can exacerbate anxiety symptoms and disrupt sleep cycles. Additionally, elevated stress hormones like cortisol and inflammatory markers such as hs-CRP may worsen these conditions. By providing a comprehensive biochemical profile, this panel empowers healthcare professionals to develop targeted strategies for anxiety and sleep support through dietary adjustments, supplementation, and lifestyle modifications.

When and Why the Magnesium, Anxiety & Sleep Support Panel May Be Ordered

Healthcare providers may recommend the Magnesium, Anxiety & Sleep Support Panel for individuals who experience:

  • Chronic anxiety, irritability, or mood disturbances

  • Difficulty falling or staying asleep, insomnia, or non-restorative sleep

  • Symptoms of stress overload, including fatigue and restlessness

  • Signs of micronutrient deficiency, such as muscle cramps, weakness, or low energy

  • Conditions linked to systemic inflammation, such as metabolic syndrome or autoimmune issues

  • Concerns about cardiovascular and nervous system health

This panel is particularly useful for patients who have tried stress-reduction or sleep-enhancing strategies without success, as it identifies underlying biochemical and nutritional imbalances that influence both mood and sleep quality.

What the Magnesium, Anxiety & Sleep Support Panel Checks For

The Magnesium, Anxiety & Sleep Support Panel evaluates a combination of metabolic, hormonal, inflammatory, and nutrient markers that impact neurological health, stress regulation, and overall energy balance. Here’s an in-depth explanation of each component:

Comprehensive Metabolic Panel (CMP)

The CMP assesses kidney and liver function, electrolytes, and protein balance, providing insight into metabolic health and organ function. Since electrolyte balance—including sodium, potassium, and chloride—is essential for nerve signaling and muscle relaxation, this test helps identify imbalances that can worsen anxiety or sleep issues.

BUN and Creatinine (Included in CMP)

Blood Urea Nitrogen (BUN) and creatinine measure kidney function and hydration status. Impaired kidney function can lead to electrolyte disturbances and contribute to fatigue and stress.

Electrolyte Panel (Included in CMP)

This includes sodium, potassium, and chloride, essential for nerve conduction and muscle function. Imbalances may result in irritability, restlessness, or poor sleep.

eGFR (Included in CMP)

The estimated glomerular filtration rate (eGFR) evaluates kidney filtration efficiency. Healthy kidney function supports optimal magnesium and electrolyte balance, crucial for anxiety and sleep regulation.

Cortisol AM

Cortisol, the primary stress hormone, peaks in the morning and influences energy, alertness, and stress response. Elevated or suppressed cortisol levels can disrupt circadian rhythms, increasing anxiety and contributing to insomnia or early waking.

hs-CRP (High-Sensitivity C-Reactive Protein)

hs-CRP is a marker of systemic inflammation, which affects neurotransmitter function and mood regulation. Chronic inflammation is strongly linked to anxiety disorders, depression, and poor sleep quality.

Magnesium

Magnesium is a key mineral for relaxation, nerve signaling, and muscle function. It modulates neurotransmitters such as GABA, which promotes calmness and sleep. Low magnesium levels are associated with heightened stress, anxiety, muscle tension, and sleep disturbances.

OmegaCheck

This test measures omega-3 fatty acids and the omega-6 to omega-3 ratio, providing insight into fatty acid balance and inflammation control. Adequate omega-3 levels support brain health, mood stability, and reduce inflammatory processes that may worsen anxiety and insomnia.

Vitamin B12 and Folate Panel

Both B12 and folate are essential for neurotransmitter synthesis and methylation, processes that influence mood regulation and cognitive function. Deficiencies can lead to anxiety, fatigue, and poor sleep quality.

Vitamin D, 25-Hydroxy, Total

Vitamin D plays a role in serotonin regulation, immune function, and sleep quality. Low levels are linked to mood disorders, anxiety, and increased inflammatory activity, all of which impact mental and physical well-being.

How Healthcare Professionals Use the Magnesium, Anxiety & Sleep Support Panel Results

Clinicians use this panel to create personalized strategies for managing anxiety, improving sleep, and restoring biochemical balance. Examples of clinical applications include:

  • Correcting magnesium deficiency through supplementation or dietary changes to improve relaxation and reduce muscle tension

  • Addressing elevated cortisol with stress-management techniques, adaptogenic herbs, or lifestyle interventions to normalize circadian rhythm

  • Reducing systemic inflammation (high hs-CRP) by optimizing diet, increasing omega-3 intake, and implementing anti-inflammatory protocols

  • Supporting mood and neurological health by correcting vitamin D, B12, and folate deficiencies

  • Ensuring electrolyte and kidney function stability to maintain hydration and nerve signaling for better sleep regulation

  • Identifying the need for additional testing or specialist referrals in cases of severe hormonal or inflammatory imbalances

By addressing these interconnected systems, healthcare providers can improve emotional well-being, enhance sleep quality, and optimize overall health.

Conclusion

The Magnesium, Anxiety & Sleep Support Panel offers a comprehensive assessment of the biochemical and nutritional factors that impact mood stability, stress response, and restful sleep. By analyzing magnesium levels, cortisol, inflammatory markers, metabolic health, and essential nutrients, this panel empowers clinicians to develop evidence-based strategies for anxiety and insomnia management. Whether the goal is improving relaxation, reducing stress, or promoting restorative sleep, this advanced panel provides the insights necessary for personalized and effective care.

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