Longevity & Healthy Aging - Advanced Lab Panel

An expanded longevity and healthy aging blood test panel that includes essential wellness markers plus deeper testing for ApoB, Lipoprotein(a), cystatin C with eGFR, ferritin, homocysteine, insulin, magnesium, uric acid, vitamin B12 and folate, iron/TIBC, Free T3, Free T4, testosterone with SHBG, OMEGACHECK™, and Cardio IQ™ lipoprotein fractionation. This Advanced panel supports a broader review of metabolic, heart, thyroid, kidney, nutrient, and aging-related biomarkers.

Serum, Blood
Phlebotomist
Longevity Panel, Healthy Aging Panel, Aging Biomarker Panel, Biological Age Panel, Preventive Wellness Panel, Health Optimization Panel, Anti-Aging Lab Panel, Vitality and Longevity Panel, Executive Wellness Panel, Proactive Health Panel

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Apolipoprotein B

Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)

NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.

Absolute Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Absolute Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Absolute Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Absolute Eosinophils

Eosinophils (eos) respond to infections caused by parasites and play a role in allergic reactions (hypersensitivities)

Absolute Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Absolute Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Absolute Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

Absolute Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Absolute Neutrophils

Neutrophils (neu) normally make up the largest number of circulating WBCs. They move into an area of damaged or infected tissue, where they engulf and destroy bacteria or sometimes fungi. Young neutrophils, recently released into circulation, are called bands.

Absolute Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Absolute Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Eosinophils

Eosinophils are specialized white blood cells produced in the bone marrow and released into the bloodstream, where they normally make up only 0–6 % of circulating leukocytes. Their cytoplasm is packed with reddish‑orange granules that contain potent enzymes (e.g., major basic protein, eosinophil cationic protein) and inflammatory mediators. When the immune system detects large, multicellular invaders—such as helminth (worm) parasites—eosinophils migrate out of the blood and surround the pathogen, releasing these granule contents to damage the parasite’s outer surface and aid its destruction. Beyond parasite defense, eosinophils act as key orchestras of the allergic response. They accumulate in tissues exposed to allergens (airways in asthma, skin in eczema, GI tract in eosinophilic esophagitis) and secrete cytokines and lipid mediators that amplify inflammation, recruit additional immune cells, and contribute to symptoms like swelling, mucus production, and itching. Because of this pro‑inflammatory role, persistently elevated eosinophil counts—termed eosinophilia—can signal allergic disorders, drug hypersensitivity, or certain autoimmune and malignant conditions. Conversely, counts drop toward zero after glucocorticoid therapy or in acute stress states, reflecting the cells’ sensitivity to hormonal and immune regulation.

Hematocrit

Hematocrit is a blood test that measures the percentage of the volume of whole blood that is made up of red blood cells. This measurement depends on the number of red blood cells and the size of red blood cells.

Hemoglobin

Serum hemoglobin is a blood test that measures the level of free hemoglobin in the liquid part of the blood (the serum). Free hemoglobin is the hemoglobin outside of the red blood cells. Most of the hemoglobin is found inside the red blood cells, not in the serum.

Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

MCH

Mean corpuscular hemoglobin (MCH) is a calculation of the average amount of oxygen-carrying hemoglobin inside a red blood cell.

MCHC

Mean corpuscular hemoglobin concentration (MCHC) is a calculation of the average percentage of hemoglobin inside a red cell.

MCV

Mean corpuscular volume (MCV) is a measurement of the average size of RBCs.

Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

MPV

Mean Platelet Volume (MPV) - When it indicates average size of platelets are small; older platelets are generally smaller than younger ones and a low MPV may mean that a condition is affecting the production of platelets by the bone marrow. When it indicates a high number of larger, younger platelets in the blood; this may be due to the bone marrow producing and releasing platelets rapidly into circulation.

Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Neutrophils

Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed.

Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Platelet Count

A platelet count is a test to measure how many platelets you have in your blood. Platelets help the blood clot. They are smaller than red or white blood cells.

Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

RDW

Red cell distribution width (RDW), which may be included in a CBC, is a calculation of the variation in the size of RBCs.

Reactive Lymphocytes (Only Reported If Detected)

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Red Blood Cell Count

An RBC count is a blood test that tells how many red blood cells (RBCs) you have. RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

White Blood Cell Count

A WBC count is a test to measure the number of white blood cells (WBCs) in the blood. WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Albumin/Globulin Ratio

The ratio of albumin to globulin (A/G ratio) is calculated from measured albumin and calculated globulin (total protein - albumin). Normally, there is a little more albumin than globulins, giving a normal A/G ratio of slightly over 1. Because disease states affect the relative amounts of albumin and globulin, the A/G ratio may provide a clue as to the cause of the change in protein levels. A low A/G ratio may reflect overproduction of globulins, such as seen in multiple myeloma or autoimmune diseases, or underproduction of albumin, such as may occur with cirrhosis, or selective loss of albumin from the circulation, as may occur with kidney disease (nephrotic syndrome). A high A/G ratio suggests underproduction of immunoglobulins as may be seen in some genetic deficiencies and in some leukemias. More specific tests, such as liver enzyme tests and serum protein electrophoresis, must be performed to make an accurate diagnosis. With a low total protein that is due to plasma expansion (dilution of the blood), the A/G ratio will typically be normal because both albumin and globulin will be diluted to the same extent.

Alkaline Phosphatase

Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone.

Alt

Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.

AST

AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bun/Creatinine Ratio

A ratio between a person’s BUN and blood creatinine to help determine what is causing these concentrations to be higher than normal. The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration. It may also be seen with increased protein, from gastrointestinal bleeding, or increased protein in the diet. The ratio may be decreased with liver disease (due to decrease in the formation of urea) and malnutrition.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.

Carbon Dioxide

CO2 is carbon dioxide. Measures the amount of carbon dioxide in the liquid part of your blood, called the serum. In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.

Chloride

Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance. This is a measure of the amount of chloride in the fluid portion (serum) of the blood.

Creatinine

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys work.

Egfr African American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

Egfr Non-Afr. American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

GFR-AFRICAN AMERICAN

GFR-NON AFRICAN AMERICAN

Globulin

Globulins is the collective term for most blood proteins other than albumin. Identifying the types of globulins can help diagnose certain disorders. Globulins are roughly divided into three groups: alpha, beta, and gamma globulins. Gamma globulines include various types of antibodies such as immunoglobulins (Ig) M, G, and A.

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Potassium

Potassium is a mineral that the body needs to work normally. It helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Protein, Total

The total protein is the total amount of two classes of proteins, albumin and globulin that are found in the fluid portion of your blood. Proteins are important parts of all cells and tissues. Your albumin helps prevent fluid from leaking out of blood vessels and your globulins are an important part of your immune system.

Sodium

Sodium is a substance that the body needs to work properly it is vital to normal body processes, including nerve and muscle function

Urea Nitrogen (Bun)

BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down. BUN measures the amount of urea nitrogen in the blood.

CYSTATIN C

eGFR

Ferritin

Ferritin is a protein found inside cells that stores iron so your body can use it later. A ferritin test indirectly measures the amount of iron in your blood. The amount of ferritin in your blood (serum ferritin level) is directly related to the amount of iron stored in your body.

Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c

HEMOGLOBIN A1C

The A1c test evaluates the average amount of glucose in the blood over the last 2 to 3 months. It does this by measuring the concentration of glycated (also often called glycosylated) hemoglobin A1c. Hemoglobin is an oxygen-transporting protein found inside red blood cells (RBCs). There are several types of normal hemoglobin, but the predominant form – about 95-98% – is hemoglobin A. As glucose circulates in the blood, some of it spontaneously binds to hemoglobin A. The hemoglobin molecules with attached glucose are called glycated hemoglobin. The higher the concentration of glucose in the blood, the more glycated hemoglobin is formed. Once the glucose binds to the hemoglobin, it remains there for the life of the red blood cell – normally about 120 days. The predominant form of glycated hemoglobin is referred to as HbA1c or A1c. A1c is produced on a daily basis and slowly cleared from the blood as older RBCs die and younger RBCs (with non-glycated hemoglobin) take their place. This test is used to monitor treatment in someone who has been diagnosed with diabetes. It helps to evaluate how well their glucose levels have been controlled by treatment over time. This test may be used to screen for and diagnose diabetes or risk of developing diabetes. In 2010, clinical practice guidelines from the American Diabetes Association (ADA) stated that A1c may be added to fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) as an option for diabetes screening and diagnosis. For monitoring purposes, an A1c of less than 7% indicates good glucose control and a lower risk of diabetic complications for the majority of diabetics. However, in 2012, the ADA and the European Association for the Study of Diabetes (EASD) issued a position statement recommending that the management of glucose control in type 2 diabetes be more "patient-centered." Data from recent studies have shown that low blood sugar (hypoglycemia) can cause complications and that people with risk of severe hypoglycemia, underlying health conditions, complications, and a limited life expectancy do not necessarily benefit from having a stringent goal of less than 7% for their A1c. The statement recommends that people work closely with their doctor to select a goal that reflects each person's individual health status and that balances risks and benefits.

Also known as: Homocysteine, Homocysteine Cardiovascular

HOMOCYSTEINE,

Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP

Hs Crp

A high-sensitivity CRP (hs-CRP) test may be used by itself, in combination with other cardiac risk markers, or in combination with a lipoprotein-associated phospholipase A2 (Lp-PLA2) test that evaluates vascular inflammation. The hs-CRP test accurately detects low concentrations of C-reactive protein to help predict a healthy person's risk of cardiovascular disease (CVD). High-sensitivity CRP is promoted by some as a test for determining a person's risk level for CVD, heart attacks, and strokes. The current thinking is that hs-CRP can play a role in the evaluation process before a person develops one of these health problems.

Also known as: Insulin (fasting)

Insulin

Insulin is a hormone that is produced and stored in the beta cells of the pancreas. It is vital for the transportation and storage of glucose at the cellular level, helps regulate blood glucose levels, and has a role in lipid metabolism. When blood glucose levels rise after a meal, insulin is released to allow glucose to move into tissue cells, especially muscle and adipose (fat) cells, where is it is used for energy production. Insulin then prompts the liver to either store the remaining excess blood glucose as glycogen for short-term energy storage and/or to use it to produce fatty acids. The fatty acids are eventually used by adipose tissue to synthesize triglycerides to form the basis of a longer term, more concentrated form of energy storage. Without insulin, glucose cannot reach most of the body's cells. Without glucose, the cells starve and blood glucose levels rise to unhealthy levels. This can cause disturbances in normal metabolic processes that result in various disorders, including kidney disease, cardiovascular disease, and vision and neurological problems. Thus, diabetes, a disorder associated with decreased insulin effects, is eventually a life-threatening condition.

Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC

% Saturation

Iron Binding Capacity

Total iron binding capacity (TIBC) is a blood test to see if you may have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.

Iron, Total

Iron is a mineral that our bodies need for many functions. For example, iron is part of hemoglobin, a protein which carries oxygen from our lungs throughout our bodies. It helps our muscles store and use oxygen. Iron is also part of many other proteins and enzymes. Your body needs the right amount of iron. If you have too little iron, you may develop iron deficiency anemia. Causes of low iron levels include blood loss, poor diet, or an inability to absorb enough iron from foods. People at higher risk of having too little iron are young children and women who are pregnant or have periods.

Also known as: Cholesterol, HDL,Fasting Lipids,Cholesterol, LDL, Fasting Lipids, Lipid Panel (fasting), Lipid Profile (fasting), Lipids

Chol/HDLC Ratio

Cholesterol, Total

Cholesterol is a waxy, fat-like substance that occurs naturally in all parts of the body. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can combine with other substances in the blood and stick to the walls of your arteries. This is called plaque. Plaque can narrow your arteries or even block them. High levels of cholesterol in the blood can increase your risk of heart disease. Your cholesterol levels tend to rise as you get older. There are usually no signs or symptoms that you have high blood cholesterol, but it can be detected with a blood test. You are likely to have high cholesterol if members of your family have it, if you are overweight or if you eat a lot of fatty foods. You can lower your cholesterol by exercising more and eating more fruits and vegetables. You also may need to take medicine to lower your cholesterol.

HDL Cholesterol

LDL-Cholesterol

Non HDL Cholesterol

Triglycerides

Triglycerides are a form of fat and a major source of energy for the body. This test measures the amount of triglycerides in the blood. Most triglycerides are found in fat (adipose) tissue, but some triglycerides circulate in the blood to provide fuel for muscles to work. After a person eats, an increased level of triglycerides is found in the blood as the body converts the energy not needed right away into fat. Triglycerides move via the blood from the gut to adipose tissue for storage. In between meals, triglycerides are released from fat tissue to be used as an energy source for the body. Most triglycerides are carried in the blood by lipoproteins called very low density lipoproteins (VLDL). High levels of triglycerides in the blood are associated with an increased risk of developing cardiovascular disease (CVD), although the reason for this is not well understood. Certain factors can contribute to high triglyceride levels and to risk of CVD, including lack of exercise, being overweight, smoking cigarettes, consuming excess alcohol, and medical conditions such as diabetes and kidney disease.

Also known as: Lipoprotein A, Lp (a), Lp(a)

Lipoprotein (A)

Lipoprotein-a, or Lp(a) are molecules made of proteins and fat. They carry cholesterol and similar substances through the blood. A high level of Lp(a) is considered a risk factor for heart disease. High levels of lipoproteins can increase the risk of heart disease. The test is done to check your risk of atherosclerosis, stroke, and heart attack.

Also known as: Ion Mobility, Cardio IQ Lipoprotein Fractionation, Ion Mobility , HDL Subfractions, IDL Subfractions, LDL Subfractions, Lipoprotein Fraction, Lipoprotein Fractionation, Lipoprotein Fractionation Ion Mobility Cardio IQ, Quest Diagnostics has replaced the VAP® Cholesterol Test with Lipoprotein Fractionation, Ion Mobility, Cardio IQ™ test

HDL Large

LDL Medium

LDL Particle Number

LDL Pattern

LDL Peak Size

LDL Small

Magnesium

ARACHIDONIC ACID

ARACHIDONIC ACID/EPA

DHA

DPA

EPA

EPA+DPA+DHA

LINOLEIC ACID

OMEGA-3 TOTAL

OMEGA-6 TOTAL

OMEGA-6/OMEGA-3 RATIO

Vitamin D, 25-Oh, D2

Vitamin D2 ((ergocalciferol,) is found in fortified foods and in most vitamin preparations and supplements. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D2 is effective when it is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, D3

Vitamin D3 (cholecalcifero) which comes from animals. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D3 are is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Also known as: Testosterone Total And Free And Sex Hormone Binding Globulin

Free Testosterone

In many cases, measurement of total testosterone provides the doctor with adequate information. However, in certain cases, for example when the level of SHBG is abnormal, a test for free or bioavailable testosterone may be performed as it may more accurately reflect the presence of a medical condition.

Sex Hormone Binding

The sex hormone binding globulin (SHBG) test measures the concentration of SHBG in the blood. SHBG is a protein that is produced by the liver and binds tightly to testosterone, dihydrotestosterone (DHT), and estradiol (an estrogen). In this bound state, it transports them in the blood as an inactive form. The amount of SHBG in circulation is affected by age and sex, by decreased or increased testosterone or estrogen production and can be affected by certain diseases and conditions such as liver disease, hyperthyroidism or hypothyroidism, and obesity. Changes in SHBG levels can affect the amount of testosterone that is available to be used by the body's tissues. A total testosterone test does not distinguish between bound and unbound testosterone but determines the overall quantity of testosterone. If a person's SHBG level is not normal, then the total testosterone may not be an accurate representation of the amount of testosterone that is available to the person's tissues.

TESTOSTERONE, TOTAL,

A testosterone test measures the amount of the male hormone, testosterone, in the blood. Both men and women produce this hormone. In males, the testicles produce most of the testosterone in the body. Levels are most often checked to evaluate signs of low testosterone: In boys -- early or late puberty and in men -- impotence, low level of sexual interest, infertility, thinning of the bones In females, the ovaries produce most of the testosterone and levels are most often checked to evaluate signs of higher testosterone levels, such as: decreased breast size, excess hair growth, increased size of the clitoris. irregular or absent menstrual periods and male-pattern baldness or hair thinning.

Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

Also known as: Serum Urate, UA

Uric Acid

Uric acid is a chemical created when the body breaks down substances called purines. Purines are found in some foods and drinks. These include liver, anchovies, mackerel, dried beans and peas, and beer. Most uric acid dissolves in blood and travels to the kidneys. From there, it passes out in urine. If your body produces too much uric acid or doesn't remove enough if it, you can get sick. A high level of uric acid in the blood is called hyperuricemia.

Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid

Folate, Serum

Folate is part of the B complex of vitamins and is measures the levels of folate in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Folate is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis.. A deficiency inr folate can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow.

Vitamin B12

Vitamin B12 is part of the B complex of vitamins and measurea the levels of vitamin B12 in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Cobalamine, or vitamin B12, is found in animal products such as red meat, fish, poultry, milk, yogurt, and eggs and is not produced in the human body. In recent years, fortified cereals, breads, and other grain products have also become important dietary sources of B12. Vitamin B12 is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis. B12 is important for nerve health. A deficiency in B12 can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow. B12 deficiency can lead to varying degrees of neuropathy, nerve damage that can cause tingling and numbness in the affected person's hands and feet.
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The Longevity & Healthy Aging - Advanced Lab Panel panel contains 22 tests with 101 biomarkers .

Overview

The Longevity & Healthy Aging Advanced Lab Panel provides a deeper look at biomarkers related to preventive wellness, cardiometabolic health, kidney function, thyroid hormone activity, blood sugar regulation, insulin patterns, cardiovascular particle risk, inherited cholesterol risk, inflammation, nutrient status, omega fatty acid status, and healthy aging.

This panel includes the foundational tests from the Essential panel and adds expanded markers that may help identify additional patterns worth reviewing with a healthcare provider.

Why Order This Panel?

Healthy aging is influenced by many overlapping systems, including blood sugar, insulin, thyroid hormones, kidney function, cholesterol particles, inherited cardiovascular risk, inflammation, nutrient status, iron status, omega fatty acids, and hormone availability.

The Advanced panel is designed for people who want a more detailed lab review than the Essential panel and may be especially helpful for adults focused on prevention, longevity, heart health, metabolic health, and long-term vitality.

This Panel May Be Helpful For People Who Want To

  • Take a deeper look at healthy aging biomarkers
  • Review heart health beyond a standard cholesterol panel
  • Evaluate ApoB and Lipoprotein(a)
  • Check blood sugar and insulin patterns
  • Review kidney function with cystatin C and eGFR
  • Evaluate thyroid hormones beyond TSH
  • Check vitamin B12, folate, vitamin D, and iron status
  • Review omega fatty acid status
  • Establish a more complete preventive wellness baseline
  • Track metabolic and cardiovascular wellness over time

Common Symptoms or Situations This Panel May Help Evaluate

This panel may be helpful for people with:

  • Low energy
  • Weight changes
  • Blood sugar concerns
  • Insulin resistance concerns
  • Cholesterol concerns
  • Family history of heart disease
  • Family history of diabetes
  • Inflammation concerns
  • Kidney health concerns
  • Thyroid-related concerns
  • Nutrient deficiency concerns
  • Preventive wellness goals
  • Healthy aging and longevity goals

What This Panel Helps Evaluate

This panel helps evaluate selected biomarkers related to:

  • Blood count patterns
  • Liver function
  • Kidney function
  • Cystatin C with eGFR
  • Blood sugar patterns
  • Insulin patterns
  • Cholesterol and triglycerides
  • ApoB particle burden
  • Lipoprotein(a)-related inherited risk
  • Advanced lipoprotein patterns
  • Inflammation
  • Homocysteine
  • Ferritin and iron status
  • Vitamin B12 and folate status
  • Vitamin D status
  • Magnesium status
  • Omega fatty acid status
  • Thyroid screening and thyroid hormone activity
  • Testosterone availability
  • Uric acid and metabolic stress
  • General metabolic wellness

What Makes This Advanced Panel Different?

The Advanced panel includes all Essential tests and adds a deeper review of longevity-related biomarkers, including ApoB, cystatin C with eGFR, ferritin, homocysteine, insulin, Lipoprotein(a), magnesium, uric acid, B12/folate, lipoprotein fractionation, OMEGACHECK™, iron/TIBC, Free T3, Free T4, and testosterone with SHBG.

This makes it a stronger option for people who want more insight into cardiometabolic, thyroid, kidney, nutrient, hormone, and healthy aging patterns.

Which Tier Is Right for Me?

Choose This Tier Best For
Essential A focused starting point for healthy aging, inflammation, blood sugar, cholesterol, thyroid screening, vitamin D, CBC, CMP, liver, and kidney function
Advanced A deeper review that adds ApoB, cystatin C with eGFR, ferritin, homocysteine, insulin, Lp(a), magnesium, uric acid, B12/folate, lipoprotein fractionation, OMEGACHECK™, iron/TIBC, Free T3, Free T4, and testosterone with SHBG
Comprehensive The broadest longevity option, adding urine albumin/creatinine, ANA, CoQ10, copper, cortisol, DHEA-S, estradiol, GGT, IGF-1, Lp-PLA2, MPO, NT-proBNP, selenium, thyroid antibodies, urinalysis, zinc, and additional wellness markers

Tests Included and Why They Matter

Apolipoprotein B

Apolipoprotein B, or ApoB, reflects the number of atherogenic cholesterol-carrying particles. This test is included because ApoB may provide additional cardiovascular risk context beyond a standard LDL cholesterol result, especially in people with high triglycerides, insulin resistance, metabolic syndrome patterns, or family history of heart disease.

CBC, includes Differential and Platelets

The CBC evaluates red blood cells, white blood cells, hemoglobin, hematocrit, platelets, and white blood cell types. This test is included because blood count patterns may provide useful context for anemia-related concerns, immune activity, inflammation clues, infection patterns, and overall wellness.

Comprehensive Metabolic Panel, CMP

The CMP evaluates glucose, liver function, kidney function, electrolytes, calcium, protein, albumin, and other metabolic markers. This test is included because healthy aging is closely connected to blood sugar balance, liver health, kidney health, hydration, electrolyte balance, and general metabolic wellness.

Cystatin C with eGFR

Cystatin C with eGFR provides an additional way to evaluate kidney filtration. This test is included because kidney function is closely connected to cardiovascular wellness, blood pressure, metabolic health, and healthy aging.

Ferritin

Ferritin measures stored iron. This test is included because ferritin provides insight into iron storage and may also be influenced by inflammation or liver-related metabolic patterns. Low ferritin may contribute to fatigue, while elevated ferritin may warrant physician review in context.

Hemoglobin A1c

Hemoglobin A1c measures average blood sugar over approximately the past two to three months. This test is included because blood sugar imbalance, prediabetes risk, and diabetes risk can affect long-term health, cardiovascular wellness, energy, weight, and healthy aging.

Homocysteine

Homocysteine is an amino acid that may be influenced by vitamin B12, folate, vitamin B6, methylation pathways, kidney function, and cardiovascular health. This test is included because elevated homocysteine may provide additional context for vascular health, B-vitamin status, and metabolic wellness.

hs-CRP

High-sensitivity C-reactive protein is a marker of inflammation. This test is included because inflammation may provide useful context for cardiovascular wellness, metabolic health, immune activity, and healthy aging patterns.

Insulin

Insulin helps move glucose from the bloodstream into cells. This test is included because elevated fasting insulin may suggest insulin resistance, which may be associated with weight gain, cravings, blood sugar changes, high triglycerides, low HDL cholesterol, and cardiometabolic risk patterns.

Lipid Panel

The Lipid Panel measures total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides. This test is included because cholesterol and triglyceride patterns are important markers for cardiovascular wellness and long-term preventive health.

Lipoprotein(a)

Lipoprotein(a), often called Lp(a), is an inherited cholesterol-related marker. This test is included because elevated Lp(a) may increase cardiovascular risk and may not be identified through a standard Lipid Panel.

Magnesium

Magnesium is involved in muscle function, nerve signaling, blood pressure regulation, glucose metabolism, heart rhythm, and energy production. This test is included because magnesium status may provide useful context for cardiometabolic health, muscle function, sleep, and wellness.

QuestAssureD™ 25-Hydroxyvitamin D, D2, D3, LC/MS/MS

Vitamin D testing measures vitamin D status. This test is included because vitamin D may be relevant to bone health, immune health, muscle function, inflammation, mood, and general healthy aging.

TSH

TSH is a key thyroid screening marker. This test is included because thyroid function may influence energy, metabolism, weight, mood, temperature regulation, heart rate, and overall wellness.

Uric Acid

Uric acid is a metabolic waste product that may be associated with gout risk, kidney stone risk, inflammation, and metabolic syndrome patterns. This test is included because elevated uric acid may provide additional context for cardiometabolic and healthy aging concerns.

Vitamin B12 and Folate Panel, Serum

This panel measures vitamin B12 and folate. These nutrients are important for red blood cell formation, nerve function, DNA synthesis, methylation, and brain health. This test is included because B12 and folate status may provide context for energy, cognition, vascular health, and healthy aging.

Lipoprotein Fractionation, Ion Mobility, Cardio IQ™

Lipoprotein fractionation provides a detailed look at cholesterol particle size and particle patterns. This test is included because advanced lipoprotein testing may provide deeper insight into cardiovascular and metabolic risk than a standard Lipid Panel alone.

OMEGACHECK™

OMEGACHECK™ evaluates omega fatty acid status. This test is included because omega-3 and omega-6 fatty acid patterns may provide insight into cardiovascular wellness, inflammation, nutrition, and metabolic health.

Iron and Total Iron Binding Capacity, TIBC

Iron and TIBC help evaluate circulating iron and iron transport capacity. This test is included because iron status may provide useful context for fatigue, oxygen transport, inflammation interpretation, and overall wellness.

T3, Free

Free T3 measures the active form of thyroid hormone available in the bloodstream. This test is included because thyroid hormone activity may influence metabolism, energy, body temperature, mood, bowel function, and mental clarity.

T4, Free

Free T4 measures the available storage form of thyroid hormone. This test is included because Free T4 provides additional thyroid context when reviewed with TSH and Free T3.

Testosterone, Total and Free and Sex Hormone Binding Globulin

This test evaluates total testosterone, free testosterone, and SHBG. It is included because testosterone availability may influence energy, strength, body composition, libido, mood, bone health, and healthy aging in both men and women.

Related Biomarker Patterns This Panel May Help Identify

This panel may help identify or rule out lab patterns related to:

  • Blood count abnormalities
  • Blood sugar imbalance
  • Insulin resistance
  • Prediabetes risk patterns
  • Cholesterol or triglyceride abnormalities
  • ApoB-related particle burden
  • Lipoprotein(a)-related inherited cardiovascular risk
  • Advanced lipoprotein particle abnormalities
  • Inflammation
  • Elevated homocysteine
  • Low vitamin D
  • Low vitamin B12 or folate
  • Iron storage or iron availability concerns
  • Thyroid hormone imbalance
  • Testosterone availability patterns
  • Kidney filtration changes
  • Magnesium status
  • Omega fatty acid balance
  • Elevated uric acid
  • Liver function changes
  • General metabolic wellness concerns

How to Prepare for This Panel

Preparation may vary depending on the specific tests included and instructions provided at checkout. In general:

  • Fasting may be recommended because this panel includes insulin, glucose-related markers, lipid testing, and metabolic testing.
  • Morning collection may be preferred for testosterone-related testing.
  • Drink water before your blood draw unless instructed otherwise.
  • Avoid unusually intense exercise before testing unless your healthcare provider advises otherwise.
  • Continue medications unless your healthcare provider tells you otherwise.
  • Bring or keep a list of medications, supplements, and health goals to discuss during your physician consultation.
  • Follow all lab collection instructions provided with your order.

What Happens After You Receive Your Results?

After your lab results are available, your results can help organize biomarkers into areas related to blood health, blood sugar, insulin, cholesterol, ApoB, Lipoprotein(a), lipoprotein patterns, inflammation, homocysteine, kidney filtration, thyroid hormones, vitamin D, B12, folate, ferritin, iron status, magnesium, omega fatty acids, testosterone availability, liver function, and metabolic wellness.

During the physician consultation, you can discuss what your results may mean, whether follow-up testing is appropriate, and what lifestyle or medical next steps may be useful based on your health history and healthy aging goals.

Related Lab Panels

Customers interested in this panel may also consider:

  • Longevity & Healthy Aging Comprehensive Lab Panel
  • Heart Health & Cholesterol Lab Panel
  • Weight Loss Resistance & Metabolism Lab Panel
  • Prediabetes & Insulin Resistance Lab Panel
  • Thyroid & Metabolism Lab Panel
  • Men’s Testosterone, Energy & Vitality Lab Panel
  • Women’s Hormone Balance & Perimenopause Lab Panel

Frequently Asked Questions

What is the Longevity & Healthy Aging Advanced Lab Panel?

The Longevity & Healthy Aging Advanced Lab Panel is an expanded blood test panel that evaluates biomarkers related to healthy aging, cardiovascular wellness, blood sugar, insulin, kidney filtration, thyroid hormones, nutrient status, inflammation, omega fatty acids, and metabolic health.

How is the Advanced panel different from the Essential panel?

The Advanced panel includes all Essential tests and adds ApoB, cystatin C with eGFR, ferritin, homocysteine, insulin, Lipoprotein(a), magnesium, uric acid, vitamin B12 and folate, lipoprotein fractionation, OMEGACHECK™, iron/TIBC, Free T3, Free T4, and testosterone with SHBG.

Why is ApoB included?

ApoB is included because it reflects atherogenic cholesterol particle burden and may provide additional cardiovascular risk context beyond LDL cholesterol alone.

Why is Lipoprotein(a) included?

Lipoprotein(a) is included because it is an inherited cholesterol-related marker that may increase cardiovascular risk and may not be detected by a standard cholesterol test.

Why is cystatin C with eGFR included?

Cystatin C with eGFR is included because kidney filtration is closely connected to cardiovascular wellness, blood pressure, metabolic health, and healthy aging.

Why are Free T3 and Free T4 included?

Free T3 and Free T4 are included to provide a more complete thyroid review than TSH alone. Thyroid hormone activity may influence energy, metabolism, weight, mood, and overall wellness.

Can this panel diagnose aging-related disease?

No. This panel does not diagnose aging-related disease. It helps evaluate selected biomarkers that may be useful to review with a healthcare provider.

Should I choose Essential, Advanced, or Comprehensive?

Choose Essential for a focused starting point, Advanced for a deeper longevity and cardiometabolic review, and Comprehensive for the broadest healthy aging biomarker evaluation.

Important Note

This lab panel is designed to help evaluate selected biomarkers that may be related to healthy aging, cardiovascular wellness, blood sugar, insulin, thyroid function, nutrient status, kidney function, inflammation, and general wellness. It is not intended to diagnose, treat, cure, or prevent any disease. Results should be reviewed with a licensed healthcare provider.

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