Ulta Lab Tests

Islet Cell Antibody Screen with Reflex to Titer

The Islet Cell Antibody Screen with Reflex to Titer detects autoantibodies directed against pancreatic islet cells, which play a key role in insulin production. The presence of islet cell antibodies suggests autoimmune destruction of beta cells, often associated with type 1 diabetes or latent autoimmune diabetes in adults (LADA). Reflex testing to titer quantifies antibody concentration for diagnostic confirmation.

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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Islet Cell Antibody

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The Islet Cell Antibody Screen with Reflex to Titer test contains 1 test with 1 biomarker .

Islet Cell Antibody Screen with Reflex to Titer

If Islet Cell Antibody Screen is positive, then Islet Cell Antibody Titer will be performed at an additional charge 

Reference Range(s)

Islet Cell Antibody ScreenNegative

  Islet Cell Antibody Titer<1.25 JDF units

Clinical Significance

Islet Cell Antibody Screen with Reflex to Titer - Type 1 diabetes is characterized by lymphocytic cell infiltrate of the pancreatic islets. Measurement of GAD-65, ICA-512, and Insulin Antibody is a highly sensitive means to assess risk and predict onset of Type 1 diabetes. There is a correlation between the number of positive antibodies and the antibody titers versus the severity of the autoimmune process.

 

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