Ulta Lab Tests

IgE Antibody Test

The IgE Antibody (Anti-IgE IgG) test detects functional IgG autoantibodies against IgE or the high-affinity FcεRI receptor, a marker found in many cases of autoimmune chronic urticaria. These antibodies trigger mast cell and basophil degranulation, producing wheals, itching, and redness. Designed via immunoassay, the test uses serum (red-top tube), with preferred overnight fasting; results under ~168 ng/mL are considered within typical reference range.

Blood
Blood Draw
Anti-IgE IgG Test
There are no preparation instructions.

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: IgE Antibody Anti IgE IgG

IgE Antibody

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The IgE Antibody Test test contains 1 test with 1 biomarker .

Clinical Significance

Chronic urticaria is a common skin disorder affecting 1 to 6% of the general population. It is characterized by repeated occurrence of short-lived cutaneous wheals accompanied by redness and itching. Autoimmune urticaria is defined by the presence of a functional IgG antibody to high-affinity IgE receptor (Fc epsilon RI alpha) or to IgE. These antibodies trigger mast cell and basophil degranulation by the engagement of Fc epsilon receptor. Functional IgG antibody to the receptor has been identified in approximately 30-40% of patients with chronic urticaria, and anti-IgE antibody has been identified in another 5% to 10%. The anti-IgE assay will quantify autoantibodies to IgE which will aid in the diagnosis and management of autoimmune chronic urticaria.

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