Fatigue, Low Energy & Brain Fog - Comprehensive Lab Panel
The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel includes 35 tests and 139 biomarkers to review fatigue, low energy, brain fog, thyroid function, iron status, blood sugar, insulin resistance, inflammation, hormones, adrenal stress, nutrients, kidney function, muscle enzymes, methylation, omega fatty acids, and mitochondria. Includes CBC, CMP, ferritin, iron/TIBC, thyroid markers, B12, folate, MMA, homocysteine, cortisol, DHEA-S, ANA, and CoQ10.
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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
Also known as: Microalbumin Random Urine with Creatinine
Creatinine, Random Urine
Microalbumin
Microalbumin/Creatinine
Also known as: ANA, ANA Screen IFA with Reflex to Titer and Pattern IFA, ANA with Reflux
ANA Screen, IFA
Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)
NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.
Absolute Band Neutrophils (Only Reported If Detected)
Absolute Basophils
Absolute Blasts (Only Reported If Detected)
Absolute Eosinophils
Absolute Lymphocytes
Absolute Metamyelocytes (Only Reported If Detected)
Absolute Monocytes
Absolute Myelocytes (Only Reported If Detected)
Absolute Neutrophils
Absolute Nucleated Rbc (Only Reported If Detected)
Absolute Promyelocytes (Only Reported If Detected)
Band Neutrophils (Only Reported If Detected)
Basophils
Blasts (Only Reported If Detected)
Eosinophils
Hematocrit
Hemoglobin
Lymphocytes
MCH
MCHC
MCV
Metamyelocytes (Only Reported If Detected)
Monocytes
MPV
Myelocytes (Only Reported If Detected)
Neutrophils
Nucleated Rbc (Only Reported If Detected)
Platelet Count
Promyelocytes (Only Reported If Detected)
RDW
Reactive Lymphocytes (Only Reported If Detected)
Red Blood Cell Count
White Blood Cell Count
Also known as: CoQ10
Coenzyme Q10
Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20
Albumin
Albumin/Globulin Ratio
Alkaline Phosphatase
Alt
AST
Bilirubin, Total
Bun/Creatinine Ratio
Calcium
Carbon Dioxide
Chloride
Creatinine
Egfr African American
Egfr Non-Afr. American
GFR-AFRICAN AMERICAN
GFR-NON AFRICAN AMERICAN
Globulin
Glucose
Potassium
Protein, Total
Sodium
Urea Nitrogen (Bun)
Also known as: Cortisol AM
Cortisol, A.M.
Also known as: CK (Total), CPK, CPK (Total), Creatine Kinase CK Total, Creatine Phosphokinase (CPK), Total CK
Creatine Kinase, Total
CYSTATIN C
eGFR
Also known as: Dehydroepiandrosterone Sulfate, DHEA SO4, DHEA Sulfate Immunoassay, DHEAS, Transdehydroandrosterone
DHEA SULFATE
Estradiol
Ferritin
Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c
HEMOGLOBIN A1C
Also known as: Homocysteine, Homocysteine Cardiovascular
HOMOCYSTEINE,
Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP
Hs Crp
Also known as: Insulin (fasting)
Insulin
Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC
% Saturation
Iron Binding Capacity
Iron, Total
Also known as: Cholesterol, HDL,Fasting Lipids,Cholesterol, LDL, Fasting Lipids, Lipid Panel (fasting), Lipid Profile (fasting), Lipids
Chol/HDLC Ratio
Cholesterol, Total
HDL Cholesterol
LDL-Cholesterol
Non HDL Cholesterol
Triglycerides
Magnesium
Also known as: Magnesium RBC
Magnesium, Rbc
Methylmalonic Acid
ARACHIDONIC ACID
ARACHIDONIC ACID/EPA
DHA
DPA
EPA
EPA+DPA+DHA
LINOLEIC ACID
OMEGA-3 TOTAL
OMEGA-6 TOTAL
OMEGA-6/OMEGA-3 RATIO
Also known as: Pregnenolone LCMSMS
Pregnenolone, LC/MS/MS
Vitamin D, 25-Oh, D2
Vitamin D, 25-Oh, D3
Vitamin D, 25-Oh, Total
Also known as: ESR, SED RATE, Sed Rate by Modified Westergren ESR
Sed Rate By Modified
Selenium
Also known as: Reverse T3, Reverse Triiodothyronine, RT3, T3 Reverse RT3 LCMSMS, Triiodothyronine Reverse
T3 Reverse, LC/MS/MS
Also known as: Free T3, FT3, T3 Free
T3, Free
Also known as: Free T4, FT4, T4 Free
T4, Free
Also known as: Testosterone Total And Free And Sex Hormone Binding Globulin
Free Testosterone
Sex Hormone Binding
TESTOSTERONE, TOTAL,
Thyroglobulin Antibodies
Thyroid Peroxidase
Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test
TSH
Also known as: UA, Complete, Urinalysis UA Complete, Urine Analysis, Complete
Amorphous Sediment (Only Reported If Detected)
Appearance
Bacteria
Bilirubin
Calcium Oxalate Crystals (Only Reported If Detected)
Casts (Only Reported If Detected)
Color
Crystals (Only Reported If Detected)
Glucose
Granular Cast (Only Reported If Detected)
Hyaline Cast
Ketones
Leukocyte Esterase
Nitrite
Occult Blood
Ph
Protein
Rbc
Reducing Substances (Only Reported If Detected)
Renal Epithelial Cells (Only Reported If Detected)
Specific Gravity
Squamous Epithelial Cells
Transitional Epithelial (Only Reported If Detected)
Triple Phosphate Crystals (Only Reported If Detected)
Uric Acid Crystals (Only Reported If Detected)
WBC
YEAST (Only Reported If Detected)
Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid
Folate, Serum
Vitamin B12
Also known as: B6, B6 Vitamin, Pyridoxal, Pyridoxal Phosphate, Pyridoxal Phosphate (PLP), Vitamin B6 Pyridoxal Phosphate
Vitamin B6
Also known as: ZN, Plasma
Zinc
The Fatigue, Low Energy & Brain Fog - Comprehensive Lab Panel panel contains 35 tests with 138 biomarkers .
Overview
The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel is designed for people who want a deeper lab-based review of common and complex biomarker patterns that may be related to persistent fatigue, low energy, brain fog, poor focus, weakness, low stamina, poor recovery, or feeling mentally and physically drained.
Fatigue and brain fog may involve many overlapping systems, including blood health, iron status, thyroid function, blood sugar regulation, insulin resistance, inflammation, autoimmune patterns, adrenal stress, sex hormones, kidney function, urine health, muscle enzymes, vitamin status, methylation, omega fatty acids, and mitochondrial energy support.
This Comprehensive panel goes beyond a basic fatigue screen by combining foundational tests such as CBC, CMP, ferritin, iron/TIBC, TSH, Free T4, vitamin D, B12, folate, A1c, hs-CRP, magnesium, and urinalysis with deeper markers such as Free T3, Reverse T3, thyroid antibodies, ANA, ESR, insulin, cortisol, DHEA-S, testosterone with SHBG, estradiol, pregnenolone, CoQ10, OMEGACHECK™, MMA, homocysteine, RBC magnesium, zinc, selenium, CK, cystatin C, and urine albumin/creatinine.
This panel does not diagnose the cause of fatigue or brain fog by itself. Results should be reviewed with a licensed healthcare provider and interpreted with symptoms, sleep, stress, medications, supplements, diet, menstrual or hormone status, medical history, and lifestyle factors.
Why Order This Panel?
The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel may be helpful for people who want a broad view of possible lab-related contributors to fatigue, reduced energy, low stamina, poor concentration, and cognitive sluggishness.
This panel may help provide insight into:
- Blood count and anemia-related patterns
- Iron storage and iron availability
- Thyroid function and autoimmune thyroid patterns
- Blood sugar and insulin resistance
- Inflammation and autoimmune screening
- Cortisol and adrenal hormone patterns
- Testosterone, estradiol, DHEA-S, and hormone availability
- B12, folate, MMA, homocysteine, B6, zinc, selenium, magnesium, and vitamin D status
- Kidney filtration and urine albumin patterns
- Muscle enzyme activity and weakness-related markers
- Omega fatty acid status
- CoQ10 and mitochondrial energy support
- General metabolic, liver, kidney, electrolyte, and urine health
This Panel May Be Helpful For People With
- Persistent fatigue
- Low energy or low stamina
- Brain fog or poor focus
- Afternoon energy crashes
- Muscle weakness or poor recovery
- Feeling tired despite sleeping
- Cold intolerance or thyroid symptoms
- Weight changes
- Sugar cravings or energy crashes
- Heavy periods or low iron history
- Vegetarian, vegan, restricted, or low-calorie diets
- Chronic inflammation concerns
- Joint pain, rashes, or autoimmune-type symptoms
- Low libido, mood changes, or hormone concerns
- Stress, burnout, or poor resilience
- Statin use or muscle symptoms
- Numbness, tingling, or neurologic-type symptoms
- Interest in a broad fatigue and brain fog baseline
What This Panel Helps Evaluate
This panel helps evaluate selected biomarkers related to:
- Fatigue and low energy
- Brain fog and cognitive wellness
- Blood health and oxygen delivery
- Iron storage and iron transport
- Thyroid hormone production, thyroid activity, and thyroid autoimmunity
- Blood sugar, insulin, and metabolic flexibility
- Inflammation and autoimmune screening
- Cortisol, DHEA-S, pregnenolone, testosterone, estradiol, and hormone balance
- B-vitamin and methylation patterns
- Magnesium, zinc, selenium, vitamin D, and nutrient support
- Kidney filtration and urine albumin patterns
- Muscle enzyme activity
- Omega fatty acid status
- Mitochondrial energy support
- General metabolic wellness
Which Tier Is Right for Me?
Essential Lab Panel
The Fatigue, Low Energy & Brain Fog Essential Lab Panel is best for people who want a focused starting point. It reviews the most common lab areas related to fatigue, including blood count, iron status, thyroid screening, blood sugar, vitamin D, B12/folate, magnesium, inflammation, CMP, and urinalysis.
Choose Essential if you want a practical first step for fatigue, low energy, or brain fog.
Advanced Lab Panel
The Fatigue, Low Energy & Brain Fog Advanced Lab Panel is best for people who want deeper insight into thyroid hormones, thyroid antibodies, insulin resistance, inflammation, muscle enzymes, cortisol, DHEA-S, testosterone, estradiol, methylation, functional B12, zinc, selenium, and RBC magnesium.
Choose Advanced if symptoms are persistent, recurring, or involve energy crashes, thyroid symptoms, hormone concerns, muscle weakness, or brain fog.
Comprehensive Lab Panel
The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel is the broadest option. It includes the Essential and Advanced categories and adds deeper kidney/urine markers, autoimmune screening with ANA, CoQ10, OMEGACHECK™, pregnenolone, Reverse T3, and expanded nutrient and mitochondrial support markers.
Choose Comprehensive if you want the broadest review of fatigue, brain fog, thyroid, hormones, inflammation, nutrients, kidney function, autoimmune patterns, and energy production.
Tests Included and Why They Matter
Blood Health, Oxygen Delivery & Iron Status
Fatigue often overlaps with blood count patterns, anemia, iron deficiency, low iron stores, and reduced oxygen delivery. This group helps evaluate whether the body has the blood and iron support needed for energy, stamina, mental clarity, and physical performance.
CBC, includes Differential and Platelets
The CBC evaluates red blood cells, white blood cells, hemoglobin, hematocrit, platelets, and white blood cell types.
This test is included because red blood cells and hemoglobin help carry oxygen throughout the body. Low hemoglobin, low hematocrit, anemia-related patterns, infection clues, immune changes, or platelet abnormalities may contribute to fatigue, weakness, dizziness, shortness of breath with exertion, low stamina, or poor recovery.
Ferritin
Ferritin measures stored iron.
This test is included because low iron stores may contribute to fatigue, low energy, low stamina, restless legs, hair shedding, heavy period-related symptoms, weakness, or poor exercise tolerance. Ferritin can also rise with inflammation, liver stress, metabolic issues, or iron overload, so it should be interpreted with iron/TIBC, CBC, hs-CRP, ESR, and symptoms.
Iron and Total Iron Binding Capacity, TIBC
Iron and TIBC help evaluate circulating iron and iron transport capacity.
This test is included because ferritin alone does not fully show iron availability. Iron/TIBC provides additional context for iron deficiency, iron overload, anemia-related patterns, oxygen delivery, fatigue, and weakness.
Thyroid Function, Thyroid Activity & Autoimmune Thyroid Patterns
Thyroid hormones help regulate metabolism, energy production, body temperature, mood, bowel function, hair and skin health, and cognitive speed. Thyroid symptoms can overlap strongly with fatigue and brain fog.
TSH
TSH is a key thyroid screening marker.
This test is included because thyroid function may influence energy, weight, metabolism, mood, body temperature, constipation, hair changes, and mental clarity. TSH provides an important starting point for thyroid-related fatigue review.
T4, Free
Free T4 measures the available form of thyroxine, a thyroid hormone.
This test is included because Free T4 provides additional thyroid hormone production context when reviewed with TSH and symptoms. It may be useful when fatigue, cold intolerance, weight changes, constipation, or low energy suggest possible thyroid involvement.
T3, Free
Free T3 measures the active form of thyroid hormone available in the bloodstream.
This test is included because T3 is closely tied to energy output, metabolism, body temperature, and mental alertness. Free T3 may provide added context when fatigue, brain fog, low metabolism, restrictive dieting, or stress patterns are present.
T3 Reverse, RT3, LC/MS/MS
Reverse T3 is an inactive thyroid hormone metabolite.
This test is included as a deeper thyroid-context marker for people with persistent fatigue, low energy, or brain fog when broader thyroid interpretation is desired. Reverse T3 should not be interpreted alone and is best reviewed with TSH, Free T4, Free T3, symptoms, nutrition status, stress, illness, and provider guidance.
Thyroid Peroxidase and Thyroglobulin Antibodies
These antibodies help evaluate autoimmune thyroid patterns.
This test is included because autoimmune thyroid activity may contribute to thyroid dysfunction and symptoms such as fatigue, brain fog, weight changes, hair shedding, mood changes, and cold intolerance. Including thyroid antibodies adds important context beyond thyroid hormone levels alone.
Blood Sugar, Insulin & Metabolic Energy
Energy crashes, cravings, sleepiness after meals, poor focus, weight changes, and fatigue may overlap with blood sugar and insulin patterns. This group helps evaluate metabolic flexibility and longer-term glucose regulation.
Hemoglobin A1c
Hemoglobin A1c measures average blood sugar over approximately the past two to three months.
This test is included because blood sugar patterns may affect energy, focus, cravings, mood, and metabolic wellness. A1c provides a longer-term view of glucose trends and may help support discussions about prediabetes, diabetes risk, and metabolic fatigue.
Insulin
Insulin helps move glucose from the bloodstream into cells.
This test is included because fasting insulin may provide context for insulin resistance, energy crashes, cravings, weight changes, and metabolic fatigue. Insulin may reveal metabolic strain even when glucose or A1c appear less obvious.
Lipid Panel
The Lipid Panel measures total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides.
This test is included because lipid patterns provide cardiometabolic context that may overlap with fatigue, insulin resistance, inflammation, weight changes, and metabolic wellness.
Inflammation, Autoimmune Screening & Immune Context
Inflammation and autoimmune patterns can contribute to fatigue, brain fog, body aches, joint pain, poor recovery, and low energy. This group helps evaluate low-grade inflammation, broader systemic inflammation, and autoimmune screening context.
hs-CRP
High-sensitivity C-reactive protein is a marker of low-grade inflammation.
This test is included because inflammation may contribute to fatigue, brain fog, metabolic stress, cardiovascular risk, and poor recovery. hs-CRP also helps interpret ferritin, which may rise with inflammation.
Sed Rate by Modified Westergren, ESR
ESR is a general inflammation marker.
This test is included because it provides a broader inflammation perspective that complements hs-CRP. ESR may be useful when fatigue overlaps with body aches, joint pain, chronic pain, inflammatory symptoms, or unexplained systemic concerns.
ANA Screen, IFA with Reflex to Titer and Pattern, IFA
ANA screening helps evaluate whether antinuclear antibodies are present.
This test is included because autoimmune patterns may overlap with fatigue, brain fog, joint pain, rashes, chronic pain, inflammation, and systemic symptoms. A positive ANA does not diagnose autoimmune disease by itself, but it may help guide provider-directed follow-up when symptoms suggest autoimmune involvement.
Adrenal, Stress & Hormone Balance
Stress hormones and sex hormones may influence energy, mood, motivation, sleep, libido, body composition, resilience, and recovery. This group helps provide context when fatigue overlaps with burnout, hormone changes, low libido, poor recovery, or stress-related symptoms.
Cortisol, A.M.
Morning cortisol helps evaluate cortisol levels during the time of day when cortisol is commonly expected to be higher.
This test is included because cortisol may provide context for stress response, sleep-wake rhythm, fatigue, burnout, blood sugar regulation, and recovery. Cortisol can be affected by sleep, stress, illness, caffeine, medications, and timing of collection.
DHEA Sulfate, Immunoassay
DHEA-S is an adrenal androgen marker.
This test is included because DHEA-S may provide context for adrenal hormone patterns, stress physiology, recovery, aging-related hormone changes, low resilience, and energy.
Pregnenolone, LC/MS/MS
Pregnenolone is a steroid hormone precursor.
This test is included because it may provide deeper context for adrenal and sex hormone pathways, stress physiology, and hormone balance. Pregnenolone is a premium marker best interpreted with cortisol, DHEA-S, sex hormones, symptoms, and provider guidance.
Testosterone, Total and Free and Sex Hormone Binding Globulin
This test evaluates total testosterone, free testosterone, and SHBG.
This test is included because testosterone availability may influence energy, libido, mood, motivation, muscle mass, body composition, strength, and recovery in both men and women. SHBG helps interpret how much testosterone is available for use by the body.
Estradiol
Estradiol is a major form of estrogen.
This test is included because estradiol may provide context for energy, mood, sleep, brain fog, menstrual changes, perimenopause, menopause, libido, bone health, and hormone balance. Interpretation should consider sex, age, cycle timing, menopause status, hormone therapy, and symptoms.
B Vitamins, Methylation & Brain Fog Support
B vitamins and methylation-related markers are important for red blood cell production, nerve function, DNA synthesis, neurotransmitter pathways, and cognitive wellness. This group is especially relevant when fatigue overlaps with brain fog, numbness, tingling, mood changes, or restricted diets.
Vitamin B12 and Folate Panel, Serum
This panel measures vitamin B12 and folate.
These nutrients support red blood cell production, nerve function, DNA synthesis, methylation, and general wellness. This test is included because B12 and folate status may provide context for fatigue, brain fog, weakness, numbness, tingling, anemia-related patterns, and cognitive concerns.
Methylmalonic Acid
Methylmalonic acid, or MMA, is a functional marker related to vitamin B12 status.
This test is included because MMA may help identify functional B12 insufficiency when serum B12 is borderline or when symptoms suggest B12-related issues. It is especially useful for brain fog, numbness, tingling, fatigue, weakness, or neurologic-type symptoms.
Homocysteine
Homocysteine is influenced by vitamin B12, folate, vitamin B6, methylation pathways, kidney function, and vascular health.
This test is included because it provides functional context for B-vitamin status, methylation, vascular wellness, and brain fog-related discussions.
Vitamin B6, Pyridoxal Phosphate
Vitamin B6 is involved in neurotransmitter pathways, methylation, amino acid metabolism, immune function, and nervous system health.
This test is included because B6 may provide context for mood, energy, neurologic symptoms, methylation support, and supplement safety.
Minerals, Nutrients, Omega Fatty Acids & Mitochondrial Energy
Nutrient status can influence energy production, cognition, muscle function, immune resilience, thyroid activity, inflammation, and recovery. This group evaluates key nutrients and energy-support markers.
Magnesium
Magnesium supports muscle function, nerve signaling, sleep, glucose metabolism, blood pressure regulation, and energy production.
This test is included because magnesium may provide context for fatigue, muscle cramps, sleep quality, anxiety-like symptoms, blood sugar patterns, and nervous system function.
Magnesium, RBC
RBC magnesium may provide additional magnesium status context compared with serum magnesium alone.
This test is included because deeper magnesium evaluation may be useful when fatigue, poor sleep, cramps, muscle symptoms, or nervous system symptoms are present.
QuestAssureD™ 25-Hydroxyvitamin D, D2, D3, LC/MS/MS
Vitamin D testing measures vitamin D status.
This test is included because vitamin D supports bone health, immune function, muscle function, inflammation balance, mood, and general wellness. Low vitamin D status may overlap with fatigue, muscle aches, and low resilience.
Zinc
Zinc supports immune function, wound healing, thyroid pathways, hormone balance, antioxidant activity, taste and smell, and tissue repair.
This test is included because zinc may provide context for immune resilience, thyroid wellness, fatigue, nutrient status, and hormone-related patterns.
Selenium
Selenium supports antioxidant enzymes and thyroid-related pathways.
This test is included because selenium may provide useful context for thyroid support, oxidative stress, immune function, and general fatigue review.
OMEGACHECK™
OMEGACHECK™ evaluates omega fatty acid status.
This test is included because omega-3 and omega-6 fatty acid patterns may provide context for inflammation balance, cardiovascular wellness, nutrition quality, brain health, and recovery.
Coenzyme Q10
Coenzyme Q10 is involved in mitochondrial energy production and antioxidant support.
This test is included because CoQ10 may provide context for cellular energy production, fatigue, statin use, muscle symptoms, and mitochondrial wellness.
Kidney, Urine & Muscle Stress Context
Kidney function, urine findings, and muscle enzymes can contribute to fatigue, weakness, and poor recovery. This group adds deeper safety and performance context.
Comprehensive Metabolic Panel, CMP
The CMP evaluates glucose, liver function, kidney function, electrolytes, calcium, albumin, total protein, and metabolic markers.
This test is included because fatigue review benefits from a broad organ-function baseline. CMP findings may provide context for hydration, electrolytes, glucose, liver enzymes, kidney markers, calcium, protein status, and metabolic wellness.
Cystatin C with eGFR
Cystatin C with eGFR provides an additional estimate of kidney filtration.
This test is included because kidney function can affect fatigue, medication clearance, metabolic waste handling, and interpretation of other markers. Cystatin C adds kidney filtration context beyond creatinine alone.
Albumin, Random Urine with Creatinine
This urine test evaluates albumin relative to creatinine.
It is included because urine albumin may provide early kidney and vascular stress context, especially when fatigue overlaps with diabetes risk, hypertension, metabolic concerns, or kidney-related issues.
Urinalysis, UA, Complete
A complete urinalysis evaluates urine markers such as protein, blood, glucose, ketones, specific gravity, pH, and other findings.
This test is included because urine findings may provide context for hydration, kidney health, urinary findings, glucose handling, ketones, protein, and blood in urine.
Creatine Kinase, CK, Total
CK is an enzyme found mainly in muscle tissue.
This test is included because CK may provide context for muscle fatigue, weakness, statin-related muscle symptoms, intense exercise, muscle inflammation, or muscle breakdown. CK can also help clarify whether AST or ALT elevations from the CMP may be muscle-related.
Related Biomarker Patterns This Panel May Help Identify
This panel may help identify or rule out lab patterns related to:
- Anemia or blood count abnormalities
- Low iron stores or abnormal iron availability
- Thyroid dysfunction or autoimmune thyroid patterns
- Blood sugar imbalance or insulin resistance
- Low-grade or systemic inflammation
- Autoimmune screening patterns
- Cortisol, DHEA-S, pregnenolone, testosterone, or estradiol patterns
- Low B12, folate, B6, or functional B12 concerns
- Methylation and homocysteine patterns
- Low magnesium or RBC magnesium status
- Low vitamin D, zinc, or selenium status
- Omega fatty acid patterns
- CoQ10 and mitochondrial energy context
- Kidney filtration or urine albumin patterns
- Urinalysis abnormalities
- Muscle enzyme elevations
Professional Safety and Interpretation Notice
This panel is designed to support fatigue, low energy, and brain fog evaluation. It does not diagnose the cause of fatigue, cognitive symptoms, thyroid disease, autoimmune disease, hormone imbalance, adrenal dysfunction, or any condition by itself. Results should be interpreted with a licensed healthcare provider and reviewed alongside symptoms, sleep, stress, diet, medications, supplements, exercise, menstrual status, age, sex, medical history, and health goals.
Do not stop or change any prescribed medication or supplement without guidance from your healthcare provider.
How to Prepare for This Panel
Preparation may vary depending on the specific tests and instructions provided with your order. In general:
- Fasting may be recommended because glucose, insulin, and lipid markers are included.
- Morning collection may be preferred for cortisol and testosterone.
- Avoid unusually intense exercise before testing if baseline CK and inflammation markers are desired.
- Bring a list of medications, supplements, hormone products, thyroid medications, and doses.
- Note symptoms such as fatigue, brain fog, sleep changes, stress, mood changes, muscle weakness, pain, or numbness/tingling.
- For women, note menstrual cycle timing, menopause status, hormone therapy, and bleeding patterns.
- Drink water normally unless instructed otherwise.
- Follow all lab collection instructions provided with your order.
What Happens After You Receive Your Results?
After your results are available, your biomarkers can help organize fatigue and brain fog findings into areas such as blood health, iron status, thyroid function, inflammation, autoimmune screening, blood sugar, insulin resistance, stress hormones, sex hormones, B-vitamin status, methylation, mineral balance, omega fatty acids, mitochondrial support, kidney function, urine health, and muscle enzymes.
During the physician consultation, you can discuss whether your results suggest the need for follow-up testing, medication review, nutrition changes, hormone review, thyroid review, lifestyle changes, sleep evaluation, or additional clinical care.
Additional Panels to Consider
Customers interested in the Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel may also consider:
- Fatigue, Low Energy & Brain Fog Essential Lab Panel
- Fatigue, Low Energy & Brain Fog Advanced Lab Panel
- Thyroid & Metabolism Lab Panel
- Stress, Cortisol, Sleep & Burnout Lab Panel
- Vitamin, Mineral & Nutrient Deficiency Lab Panel
- Inflammation, Autoimmune & Chronic Pain Lab Panel
- Prediabetes & Insulin Resistance Lab Panel
- Women’s Hormone Balance & Perimenopause Lab Panel
- Men’s Testosterone, Energy & Vitality Lab Panel
- Medication & Supplement Safety Lab Panel
- Heavy Metals & Environmental Toxins Lab Panel
- Longevity & Healthy Aging Lab Panel
FAQ: Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel
What is the Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel?
The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel is a broad blood and urine test panel that evaluates biomarkers related to anemia, iron status, thyroid function, inflammation, autoimmune screening, blood sugar, insulin resistance, hormones, adrenal stress, nutrients, methylation, kidney function, urine health, muscle enzymes, omega fatty acids, and mitochondrial energy support.
What blood tests are commonly reviewed for fatigue?
Common fatigue-related blood tests may include CBC, CMP, ferritin, iron/TIBC, TSH, Free T4, vitamin B12, folate, vitamin D, magnesium, A1c, inflammation markers, and thyroid antibodies. This Comprehensive panel expands beyond those basics with insulin, Free T3, Reverse T3, ANA, cortisol, DHEA-S, testosterone, estradiol, CoQ10, OMEGACHECK™, MMA, homocysteine, zinc, selenium, cystatin C, and urinalysis.
Does this panel help evaluate brain fog?
This panel includes markers that may be useful when brain fog overlaps with B12 or folate concerns, thyroid patterns, blood sugar imbalance, inflammation, hormone changes, sleep-stress patterns, omega fatty acid status, kidney function, or nutrient deficiencies. It does not diagnose the cause of brain fog by itself.
Why are thyroid markers included?
Thyroid function can affect energy, metabolism, mood, focus, weight, body temperature, hair, skin, and bowel patterns. This panel includes TSH, Free T4, Free T3, Reverse T3, and thyroid antibodies for a deeper thyroid review.
Why are ferritin and iron/TIBC included?
Ferritin measures stored iron, while iron/TIBC evaluates circulating iron and iron transport. Iron status may provide useful context for fatigue, weakness, low stamina, heavy periods, restless legs, dizziness, and anemia-related patterns.
Why are B12, folate, MMA, homocysteine, and B6 included?
These markers help evaluate B-vitamin status, methylation, red blood cell production, nerve function, and brain fog-related nutrient patterns. MMA adds functional B12 context, while homocysteine can reflect B-vitamin and methylation-related patterns.
Why are cortisol, DHEA-S, and pregnenolone included?
These markers provide stress-hormone and adrenal pathway context. They may be useful when fatigue overlaps with burnout, poor resilience, poor recovery, sleep-wake issues, low motivation, or stress-related symptoms.
Why are testosterone and estradiol included?
Testosterone and estradiol may provide hormone-balance context for energy, mood, libido, sleep, body composition, strength, motivation, and perimenopause, menopause, or low-testosterone concerns.
Why are inflammation and autoimmune markers included?
hs-CRP and ESR provide inflammation context, while ANA screening may help identify autoimmune patterns that may require provider-guided follow-up when fatigue overlaps with joint pain, rashes, chronic pain, or systemic symptoms.
Why is CoQ10 included?
CoQ10 supports mitochondrial energy production and antioxidant function. It may provide context for fatigue, muscle symptoms, statin use, or energy-production concerns.
Can this panel diagnose chronic fatigue syndrome?
No. This panel does not diagnose chronic fatigue syndrome, ME/CFS, autoimmune disease, thyroid disease, adrenal disease, or any condition by itself. It helps evaluate selected biomarkers that may be useful to review with a licensed healthcare provider.
Should I choose Essential, Advanced, or Comprehensive?
Choose Essential for a focused fatigue baseline, Advanced for deeper thyroid, metabolic, hormone, inflammation, and nutrient testing, and Comprehensive for the broadest review of fatigue, brain fog, autoimmune, kidney, hormone, methylation, omega, and mitochondrial markers.
Important Note
This panel is designed to help evaluate selected biomarkers that may be related to fatigue, low energy, brain fog, thyroid function, iron status, inflammation, blood sugar, hormones, adrenal stress, nutrient status, kidney function, urine health, omega fatty acid status, and mitochondrial energy support. It is not intended to diagnose, treat, cure, or prevent disease by itself. Results should be reviewed with a licensed healthcare provider.