Fatigue, Low Energy & Brain Fog - Comprehensive Lab Panel

The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel includes 35 tests and 139 biomarkers to review fatigue, low energy, brain fog, thyroid function, iron status, blood sugar, insulin resistance, inflammation, hormones, adrenal stress, nutrients, kidney function, muscle enzymes, methylation, omega fatty acids, and mitochondria. Includes CBC, CMP, ferritin, iron/TIBC, thyroid markers, B12, folate, MMA, homocysteine, cortisol, DHEA-S, ANA, and CoQ10.

Urine, Blood, Serum, Other, Random, Plasma-Unspecified Vial Pour
Phlebotomist
Fatigue, Low Energy & Brain Fog - Comprehensive Lab Panel: Fatigue Comprehensive Panel, Comprehensive Fatigue Blood Test, Brain Fog Comprehensive Panel, Chronic Fatigue Lab Panel, Fatigue and Hormone Panel, Fatigue and Thyroid Panel, Energy

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Microalbumin Random Urine with Creatinine

Creatinine, Random Urine

Microalbumin

Microalbumin/Creatinine

Also known as: ANA, ANA Screen IFA with Reflex to Titer and Pattern IFA, ANA with Reflux

ANA Screen, IFA

The antinuclear antibody (ANA) test is ordered to help screen for autoimmune disorders and is most often used as one of the tests to diagnose systemic lupus erythematosus (SLE).

Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)

NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.

Absolute Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Absolute Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Absolute Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Absolute Eosinophils

Eosinophils (eos) respond to infections caused by parasites and play a role in allergic reactions (hypersensitivities)

Absolute Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Absolute Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Absolute Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

Absolute Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Absolute Neutrophils

Neutrophils (neu) normally make up the largest number of circulating WBCs. They move into an area of damaged or infected tissue, where they engulf and destroy bacteria or sometimes fungi. Young neutrophils, recently released into circulation, are called bands.

Absolute Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Absolute Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Eosinophils

Eosinophils are specialized white blood cells produced in the bone marrow and released into the bloodstream, where they normally make up only 0–6 % of circulating leukocytes. Their cytoplasm is packed with reddish‑orange granules that contain potent enzymes (e.g., major basic protein, eosinophil cationic protein) and inflammatory mediators. When the immune system detects large, multicellular invaders—such as helminth (worm) parasites—eosinophils migrate out of the blood and surround the pathogen, releasing these granule contents to damage the parasite’s outer surface and aid its destruction. Beyond parasite defense, eosinophils act as key orchestras of the allergic response. They accumulate in tissues exposed to allergens (airways in asthma, skin in eczema, GI tract in eosinophilic esophagitis) and secrete cytokines and lipid mediators that amplify inflammation, recruit additional immune cells, and contribute to symptoms like swelling, mucus production, and itching. Because of this pro‑inflammatory role, persistently elevated eosinophil counts—termed eosinophilia—can signal allergic disorders, drug hypersensitivity, or certain autoimmune and malignant conditions. Conversely, counts drop toward zero after glucocorticoid therapy or in acute stress states, reflecting the cells’ sensitivity to hormonal and immune regulation.

Hematocrit

Hematocrit is a blood test that measures the percentage of the volume of whole blood that is made up of red blood cells. This measurement depends on the number of red blood cells and the size of red blood cells.

Hemoglobin

Serum hemoglobin is a blood test that measures the level of free hemoglobin in the liquid part of the blood (the serum). Free hemoglobin is the hemoglobin outside of the red blood cells. Most of the hemoglobin is found inside the red blood cells, not in the serum.

Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

MCH

Mean corpuscular hemoglobin (MCH) is a calculation of the average amount of oxygen-carrying hemoglobin inside a red blood cell.

MCHC

Mean corpuscular hemoglobin concentration (MCHC) is a calculation of the average percentage of hemoglobin inside a red cell.

MCV

Mean corpuscular volume (MCV) is a measurement of the average size of RBCs.

Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

MPV

Mean Platelet Volume (MPV) - When it indicates average size of platelets are small; older platelets are generally smaller than younger ones and a low MPV may mean that a condition is affecting the production of platelets by the bone marrow. When it indicates a high number of larger, younger platelets in the blood; this may be due to the bone marrow producing and releasing platelets rapidly into circulation.

Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Neutrophils

Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed.

Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Platelet Count

A platelet count is a test to measure how many platelets you have in your blood. Platelets help the blood clot. They are smaller than red or white blood cells.

Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

RDW

Red cell distribution width (RDW), which may be included in a CBC, is a calculation of the variation in the size of RBCs.

Reactive Lymphocytes (Only Reported If Detected)

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Red Blood Cell Count

An RBC count is a blood test that tells how many red blood cells (RBCs) you have. RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

White Blood Cell Count

A WBC count is a test to measure the number of white blood cells (WBCs) in the blood. WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

Also known as: CoQ10

Coenzyme Q10

Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Albumin/Globulin Ratio

The ratio of albumin to globulin (A/G ratio) is calculated from measured albumin and calculated globulin (total protein - albumin). Normally, there is a little more albumin than globulins, giving a normal A/G ratio of slightly over 1. Because disease states affect the relative amounts of albumin and globulin, the A/G ratio may provide a clue as to the cause of the change in protein levels. A low A/G ratio may reflect overproduction of globulins, such as seen in multiple myeloma or autoimmune diseases, or underproduction of albumin, such as may occur with cirrhosis, or selective loss of albumin from the circulation, as may occur with kidney disease (nephrotic syndrome). A high A/G ratio suggests underproduction of immunoglobulins as may be seen in some genetic deficiencies and in some leukemias. More specific tests, such as liver enzyme tests and serum protein electrophoresis, must be performed to make an accurate diagnosis. With a low total protein that is due to plasma expansion (dilution of the blood), the A/G ratio will typically be normal because both albumin and globulin will be diluted to the same extent.

Alkaline Phosphatase

Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone.

Alt

Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.

AST

AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bun/Creatinine Ratio

A ratio between a person’s BUN and blood creatinine to help determine what is causing these concentrations to be higher than normal. The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration. It may also be seen with increased protein, from gastrointestinal bleeding, or increased protein in the diet. The ratio may be decreased with liver disease (due to decrease in the formation of urea) and malnutrition.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.

Carbon Dioxide

CO2 is carbon dioxide. Measures the amount of carbon dioxide in the liquid part of your blood, called the serum. In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.

Chloride

Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance. This is a measure of the amount of chloride in the fluid portion (serum) of the blood.

Creatinine

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys work.

Egfr African American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

Egfr Non-Afr. American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

GFR-AFRICAN AMERICAN

GFR-NON AFRICAN AMERICAN

Globulin

Globulins is the collective term for most blood proteins other than albumin. Identifying the types of globulins can help diagnose certain disorders. Globulins are roughly divided into three groups: alpha, beta, and gamma globulins. Gamma globulines include various types of antibodies such as immunoglobulins (Ig) M, G, and A.

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Potassium

Potassium is a mineral that the body needs to work normally. It helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Protein, Total

The total protein is the total amount of two classes of proteins, albumin and globulin that are found in the fluid portion of your blood. Proteins are important parts of all cells and tissues. Your albumin helps prevent fluid from leaking out of blood vessels and your globulins are an important part of your immune system.

Sodium

Sodium is a substance that the body needs to work properly it is vital to normal body processes, including nerve and muscle function

Urea Nitrogen (Bun)

BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down. BUN measures the amount of urea nitrogen in the blood.

Also known as: Cortisol AM

Cortisol, A.M.

A cortisol level is a blood test that measures the amount of cortisol, a steroid hormone produced by the adrenal gland. The test is done to check for increased or decreased cortisol production. Cortisol is a steroid hormone released from the adrenal gland in response to ACTH, a hormone from the pituitary gland in the brain. Cortisol affects many different body systems. It plays a role in: bone, circulatory system, immune system. metabolism of fats, carbohydrates, and protein. ervous system and stress responses.

Also known as: CK (Total), CPK, CPK (Total), Creatine Kinase CK Total, Creatine Phosphokinase (CPK), Total CK

Creatine Kinase, Total

CYSTATIN C

eGFR

Also known as: Dehydroepiandrosterone Sulfate, DHEA SO4, DHEA Sulfate Immunoassay, DHEAS, Transdehydroandrosterone

DHEA SULFATE

DHEA-sulfate test measures the amount of DHEA-sulfate in the blood. DHEA-sulfate is a weak male hormone (androgen) produced by the adrenal gland in both men and women.

Estradiol

Estradiol (estradiol-17 beta, E2) is part of an estrogen that is a group of steroids that regulate the menstrual cycle and function as the main female sex hormones. Estrogens are responsible for the development of female sex organs and secondary sex characteristics and are tied to the menstrual cycle and pregnancy. They are considered the main sex hormones in women and are present in small quantities in men. Estradiol (E2) is the predominant form of estrogen and is produced primarily in the ovaries with additional amounts produced by the adrenal glands in women and in the testes and adrenal glands in men. Estradiol levels are used in evaluating ovarian function. Estradiol levels are increased in cases of early (precocious) puberty in girls and gynecomastia in men. Its main use has been in the differential diagnosis of amenorrhea – for example, to determine whether the cause is menopause, pregnancy, or a medical problem. In assisted reproductive technology (ART), serial measurements are used to monitor follicle development in the ovary in the days prior to in vitro fertilization. Estradiol is also sometimes used to monitor menopausal hormone replacement therapy.

Ferritin

Ferritin is a protein found inside cells that stores iron so your body can use it later. A ferritin test indirectly measures the amount of iron in your blood. The amount of ferritin in your blood (serum ferritin level) is directly related to the amount of iron stored in your body.

Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c

HEMOGLOBIN A1C

The A1c test evaluates the average amount of glucose in the blood over the last 2 to 3 months. It does this by measuring the concentration of glycated (also often called glycosylated) hemoglobin A1c. Hemoglobin is an oxygen-transporting protein found inside red blood cells (RBCs). There are several types of normal hemoglobin, but the predominant form – about 95-98% – is hemoglobin A. As glucose circulates in the blood, some of it spontaneously binds to hemoglobin A. The hemoglobin molecules with attached glucose are called glycated hemoglobin. The higher the concentration of glucose in the blood, the more glycated hemoglobin is formed. Once the glucose binds to the hemoglobin, it remains there for the life of the red blood cell – normally about 120 days. The predominant form of glycated hemoglobin is referred to as HbA1c or A1c. A1c is produced on a daily basis and slowly cleared from the blood as older RBCs die and younger RBCs (with non-glycated hemoglobin) take their place. This test is used to monitor treatment in someone who has been diagnosed with diabetes. It helps to evaluate how well their glucose levels have been controlled by treatment over time. This test may be used to screen for and diagnose diabetes or risk of developing diabetes. In 2010, clinical practice guidelines from the American Diabetes Association (ADA) stated that A1c may be added to fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) as an option for diabetes screening and diagnosis. For monitoring purposes, an A1c of less than 7% indicates good glucose control and a lower risk of diabetic complications for the majority of diabetics. However, in 2012, the ADA and the European Association for the Study of Diabetes (EASD) issued a position statement recommending that the management of glucose control in type 2 diabetes be more "patient-centered." Data from recent studies have shown that low blood sugar (hypoglycemia) can cause complications and that people with risk of severe hypoglycemia, underlying health conditions, complications, and a limited life expectancy do not necessarily benefit from having a stringent goal of less than 7% for their A1c. The statement recommends that people work closely with their doctor to select a goal that reflects each person's individual health status and that balances risks and benefits.

Also known as: Homocysteine, Homocysteine Cardiovascular

HOMOCYSTEINE,

Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP

Hs Crp

A high-sensitivity CRP (hs-CRP) test may be used by itself, in combination with other cardiac risk markers, or in combination with a lipoprotein-associated phospholipase A2 (Lp-PLA2) test that evaluates vascular inflammation. The hs-CRP test accurately detects low concentrations of C-reactive protein to help predict a healthy person's risk of cardiovascular disease (CVD). High-sensitivity CRP is promoted by some as a test for determining a person's risk level for CVD, heart attacks, and strokes. The current thinking is that hs-CRP can play a role in the evaluation process before a person develops one of these health problems.

Also known as: Insulin (fasting)

Insulin

Insulin is a hormone that is produced and stored in the beta cells of the pancreas. It is vital for the transportation and storage of glucose at the cellular level, helps regulate blood glucose levels, and has a role in lipid metabolism. When blood glucose levels rise after a meal, insulin is released to allow glucose to move into tissue cells, especially muscle and adipose (fat) cells, where is it is used for energy production. Insulin then prompts the liver to either store the remaining excess blood glucose as glycogen for short-term energy storage and/or to use it to produce fatty acids. The fatty acids are eventually used by adipose tissue to synthesize triglycerides to form the basis of a longer term, more concentrated form of energy storage. Without insulin, glucose cannot reach most of the body's cells. Without glucose, the cells starve and blood glucose levels rise to unhealthy levels. This can cause disturbances in normal metabolic processes that result in various disorders, including kidney disease, cardiovascular disease, and vision and neurological problems. Thus, diabetes, a disorder associated with decreased insulin effects, is eventually a life-threatening condition.

Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC

% Saturation

Iron Binding Capacity

Total iron binding capacity (TIBC) is a blood test to see if you may have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.

Iron, Total

Iron is a mineral that our bodies need for many functions. For example, iron is part of hemoglobin, a protein which carries oxygen from our lungs throughout our bodies. It helps our muscles store and use oxygen. Iron is also part of many other proteins and enzymes. Your body needs the right amount of iron. If you have too little iron, you may develop iron deficiency anemia. Causes of low iron levels include blood loss, poor diet, or an inability to absorb enough iron from foods. People at higher risk of having too little iron are young children and women who are pregnant or have periods.

Also known as: Cholesterol, HDL,Fasting Lipids,Cholesterol, LDL, Fasting Lipids, Lipid Panel (fasting), Lipid Profile (fasting), Lipids

Chol/HDLC Ratio

Cholesterol, Total

Cholesterol is a waxy, fat-like substance that occurs naturally in all parts of the body. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can combine with other substances in the blood and stick to the walls of your arteries. This is called plaque. Plaque can narrow your arteries or even block them. High levels of cholesterol in the blood can increase your risk of heart disease. Your cholesterol levels tend to rise as you get older. There are usually no signs or symptoms that you have high blood cholesterol, but it can be detected with a blood test. You are likely to have high cholesterol if members of your family have it, if you are overweight or if you eat a lot of fatty foods. You can lower your cholesterol by exercising more and eating more fruits and vegetables. You also may need to take medicine to lower your cholesterol.

HDL Cholesterol

LDL-Cholesterol

Non HDL Cholesterol

Triglycerides

Triglycerides are a form of fat and a major source of energy for the body. This test measures the amount of triglycerides in the blood. Most triglycerides are found in fat (adipose) tissue, but some triglycerides circulate in the blood to provide fuel for muscles to work. After a person eats, an increased level of triglycerides is found in the blood as the body converts the energy not needed right away into fat. Triglycerides move via the blood from the gut to adipose tissue for storage. In between meals, triglycerides are released from fat tissue to be used as an energy source for the body. Most triglycerides are carried in the blood by lipoproteins called very low density lipoproteins (VLDL). High levels of triglycerides in the blood are associated with an increased risk of developing cardiovascular disease (CVD), although the reason for this is not well understood. Certain factors can contribute to high triglyceride levels and to risk of CVD, including lack of exercise, being overweight, smoking cigarettes, consuming excess alcohol, and medical conditions such as diabetes and kidney disease.

Magnesium

Also known as: Magnesium RBC

Magnesium, Rbc

About half of the body's magnesium is found in bone. The other half is found inside cells of body tissues and organs. Magnesium is needed for nearly all chemical processes in the body. It helps maintain normal muscle and nerve function, and keeps the bones strong. Magnesium is also needed for the heart to function normally and to help regulate blood pressure. Magnesium also helps the body control blood sugar level and helps support the body's defense (immune) system.

Methylmalonic Acid

ARACHIDONIC ACID

ARACHIDONIC ACID/EPA

DHA

DPA

EPA

EPA+DPA+DHA

LINOLEIC ACID

OMEGA-3 TOTAL

OMEGA-6 TOTAL

OMEGA-6/OMEGA-3 RATIO

Also known as: Pregnenolone LCMSMS

Pregnenolone, LC/MS/MS

Vitamin D, 25-Oh, D2

Vitamin D2 ((ergocalciferol,) is found in fortified foods and in most vitamin preparations and supplements. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D2 is effective when it is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, D3

Vitamin D3 (cholecalcifero) which comes from animals. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D3 are is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Also known as: ESR, SED RATE, Sed Rate by Modified Westergren ESR

Sed Rate By Modified

Erythrocyte sedimentation rate (ESR) is an indirect measure of the degree of inflammation present in the body. It actually measures the rate of fall (sedimentation) of erythrocytes (red blood cells) in a sample of blood.

Selenium

Also known as: Reverse T3, Reverse Triiodothyronine, RT3, T3 Reverse RT3 LCMSMS, Triiodothyronine Reverse

T3 Reverse, LC/MS/MS

Reverse T3 produced in the thyroid comes from the conversion of the storage hormone T4. Your body, especially the liver, can constantly be converting T4 to RT3 as a way to get rid of any unneeded T4. In any given day approx. 40% of T4 goes to T3 and 20% of T4 goes to Reverse T3. However in any situation where your body needs to conserve energy and focus on something else, it will change the above percentages, changing the conversion of RT3 to 50% or more, and the T3 goes down, down. Examples are emotional, physical, or biological stress, such as being chronically or acutely sick (the flu, pneumonia, etc), after surgery, after a car accident or any acute injury, chronic stress causing high cortisol, being exposed to an extremely cold environment, diabetes, aging, or even being on drugs like beta blockers and amiodarone.

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Also known as: Testosterone Total And Free And Sex Hormone Binding Globulin

Free Testosterone

In many cases, measurement of total testosterone provides the doctor with adequate information. However, in certain cases, for example when the level of SHBG is abnormal, a test for free or bioavailable testosterone may be performed as it may more accurately reflect the presence of a medical condition.

Sex Hormone Binding

The sex hormone binding globulin (SHBG) test measures the concentration of SHBG in the blood. SHBG is a protein that is produced by the liver and binds tightly to testosterone, dihydrotestosterone (DHT), and estradiol (an estrogen). In this bound state, it transports them in the blood as an inactive form. The amount of SHBG in circulation is affected by age and sex, by decreased or increased testosterone or estrogen production and can be affected by certain diseases and conditions such as liver disease, hyperthyroidism or hypothyroidism, and obesity. Changes in SHBG levels can affect the amount of testosterone that is available to be used by the body's tissues. A total testosterone test does not distinguish between bound and unbound testosterone but determines the overall quantity of testosterone. If a person's SHBG level is not normal, then the total testosterone may not be an accurate representation of the amount of testosterone that is available to the person's tissues.

TESTOSTERONE, TOTAL,

A testosterone test measures the amount of the male hormone, testosterone, in the blood. Both men and women produce this hormone. In males, the testicles produce most of the testosterone in the body. Levels are most often checked to evaluate signs of low testosterone: In boys -- early or late puberty and in men -- impotence, low level of sexual interest, infertility, thinning of the bones In females, the ovaries produce most of the testosterone and levels are most often checked to evaluate signs of higher testosterone levels, such as: decreased breast size, excess hair growth, increased size of the clitoris. irregular or absent menstrual periods and male-pattern baldness or hair thinning.

Thyroglobulin Antibodies

Measurement of thyroglobulin antibodies is useful in the diagnosis and management of a variety of thyroid disorders including Hashimoto's thyroiditis, Graves Disease and certain types of goiter.

Thyroid Peroxidase

Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

Also known as: UA, Complete, Urinalysis UA Complete, Urine Analysis, Complete

Amorphous Sediment (Only Reported If Detected)

Appearance

Bacteria

Bacteria are living things that have only one cell. Most bacteria won't hurt you - less than 1 percent of the different types make people sick. Many are helpful. Some bacteria help to digest food, destroy disease-causing cells, and give the body needed vitamins. But infectious bacteria can make you ill. They reproduce quickly in your body. Many give off chemicals called toxins, which can damage tissue and make you sick. Examples of bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli.

Bilirubin

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Calcium Oxalate Crystals (Only Reported If Detected)

Calcium oxalate is a chemical compound that forms envelope-shaped crystals. A major constituent of human kidney stones.

Casts (Only Reported If Detected)

Urinary casts are cylindrical structures produced by the kidney and present in the urine in certain disease states. They form in the distal convoluted tubule and collecting ducts of nephrons, then dislodge and pass into the urine, where they can be detected by microscopy.

Color

Crystals (Only Reported If Detected)

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Granular Cast (Only Reported If Detected)

The second-most common type of cast, granular casts can result either from the breakdown of cellular casts or the inclusion of aggregates of plasma proteins (e.g., albumin) or immunoglobulin light chains. Depending on the size of inclusions, they can be classified as fine or coarse, though the distinction has no diagnostic significance. Their appearance is generally more cigar-shaped and of a higher refractive index than hyaline casts. While most often indicative of chronic renal disease, these casts, as with hyaline casts, can also be seen for a short time following strenuous exercise

Hyaline Cast

Urinary casts are tiny tube-shaped particles. Urinary casts may be made up of white blood cells, red blood cells, kidney cells, or substances such as protein or fat. The most common type of cast, hyaline casts are solidified Tamm-Horsfall mucoprotein secreted from the tubular epithelial cells of individual nephrons. Low urine flow, concentrated urine, or an acidic environment can contribute to the formation of hyaline casts, and, as such, they may be seen in normal individuals in dehydration or vigorous exercise. Hyaline casts are cylindrical and clear, with a low refractive index,

Ketones

Ketones are substances produced in the liver when fat cells break down in the blood. A serum ketone test is a measurement of how many ketones are in the blood.

Leukocyte Esterase

Leukocyte esterase is a urine test to look for white blood cells and other signs associated with infection.

Nitrite

Occult Blood

The test looks for hidden (occult) blood in a specimen sample. It can find blood even if you cannot see it yourself.

Ph

Level of acid

Protein

Body fluids contain many different proteins that serve diverse functions such as transport of nutrients, removal of toxins, control of metabolic processes, and defense against invaders. Protein electrophoresis is a method for separating these proteins based on their size and electrical charge. When body fluids are separated by electrophoresis, they form a characteristic pattern of bands of different widths and intensities, reflecting the mixture of proteins present. This pattern is divided into five fractions, called albumin, alpha 1, alpha 2, beta, and gamma. In some cases, the beta fraction is further divided into beta 1 and beta 2. Albumin, which is produced in the liver, accounts for about 60% of the protein in the blood. "Globulins" is a collective term used to refer to proteins other than albumin. With the exception of the immunoglobulins and some complement proteins, most of the globulins are also produced in the liver. Immunofixation electrophoresis (IFE) is a method used to identify abnormal bands seen on serum, urine, or CSF protein electrophoresis, as to which type of antibody (immunoglobulin) is present.

Rbc

RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

Reducing Substances (Only Reported If Detected)

Renal Epithelial Cells (Only Reported If Detected)

Specific Gravity

Squamous Epithelial Cells

Transitional Epithelial (Only Reported If Detected)

Triple Phosphate Crystals (Only Reported If Detected)

Struvite stones (triple phosphate/magnesium ammonium phosphate) - about 10–15% of urinary calculi are composed of struvite (ammonium magnesium phosphate, NH4MgPO4·6H2O).[44] Struvite stones (also known as "infection stones", urease or triple-phosphate stones), form most often in the presence of infection by urea-splitting bacteria

Uric Acid Crystals (Only Reported If Detected)

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

WBC

WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

YEAST (Only Reported If Detected)

Candida is the scientific name for yeast. It is a fungus that lives almost everywhere, including in your body. Usually, your immune system keeps yeast under control. If you are sick or taking antibiotics, it can multiply and cause an infection.

Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid

Folate, Serum

Folate is part of the B complex of vitamins and is measures the levels of folate in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Folate is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis.. A deficiency inr folate can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow.

Vitamin B12

Vitamin B12 is part of the B complex of vitamins and measurea the levels of vitamin B12 in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Cobalamine, or vitamin B12, is found in animal products such as red meat, fish, poultry, milk, yogurt, and eggs and is not produced in the human body. In recent years, fortified cereals, breads, and other grain products have also become important dietary sources of B12. Vitamin B12 is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis. B12 is important for nerve health. A deficiency in B12 can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow. B12 deficiency can lead to varying degrees of neuropathy, nerve damage that can cause tingling and numbness in the affected person's hands and feet.

Also known as: B6, B6 Vitamin, Pyridoxal, Pyridoxal Phosphate, Pyridoxal Phosphate (PLP), Vitamin B6 Pyridoxal Phosphate

Vitamin B6

Also known as: ZN, Plasma

Zinc

*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through a national lab. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Fatigue, Low Energy & Brain Fog - Comprehensive Lab Panel panel contains 35 tests with 138 biomarkers .

Overview

The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel is designed for people who want a deeper lab-based review of common and complex biomarker patterns that may be related to persistent fatigue, low energy, brain fog, poor focus, weakness, low stamina, poor recovery, or feeling mentally and physically drained.

Fatigue and brain fog may involve many overlapping systems, including blood health, iron status, thyroid function, blood sugar regulation, insulin resistance, inflammation, autoimmune patterns, adrenal stress, sex hormones, kidney function, urine health, muscle enzymes, vitamin status, methylation, omega fatty acids, and mitochondrial energy support.

This Comprehensive panel goes beyond a basic fatigue screen by combining foundational tests such as CBC, CMP, ferritin, iron/TIBC, TSH, Free T4, vitamin D, B12, folate, A1c, hs-CRP, magnesium, and urinalysis with deeper markers such as Free T3, Reverse T3, thyroid antibodies, ANA, ESR, insulin, cortisol, DHEA-S, testosterone with SHBG, estradiol, pregnenolone, CoQ10, OMEGACHECK™, MMA, homocysteine, RBC magnesium, zinc, selenium, CK, cystatin C, and urine albumin/creatinine.

This panel does not diagnose the cause of fatigue or brain fog by itself. Results should be reviewed with a licensed healthcare provider and interpreted with symptoms, sleep, stress, medications, supplements, diet, menstrual or hormone status, medical history, and lifestyle factors.


Why Order This Panel?

The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel may be helpful for people who want a broad view of possible lab-related contributors to fatigue, reduced energy, low stamina, poor concentration, and cognitive sluggishness.

This panel may help provide insight into:

  • Blood count and anemia-related patterns
  • Iron storage and iron availability
  • Thyroid function and autoimmune thyroid patterns
  • Blood sugar and insulin resistance
  • Inflammation and autoimmune screening
  • Cortisol and adrenal hormone patterns
  • Testosterone, estradiol, DHEA-S, and hormone availability
  • B12, folate, MMA, homocysteine, B6, zinc, selenium, magnesium, and vitamin D status
  • Kidney filtration and urine albumin patterns
  • Muscle enzyme activity and weakness-related markers
  • Omega fatty acid status
  • CoQ10 and mitochondrial energy support
  • General metabolic, liver, kidney, electrolyte, and urine health

This Panel May Be Helpful For People With

  • Persistent fatigue
  • Low energy or low stamina
  • Brain fog or poor focus
  • Afternoon energy crashes
  • Muscle weakness or poor recovery
  • Feeling tired despite sleeping
  • Cold intolerance or thyroid symptoms
  • Weight changes
  • Sugar cravings or energy crashes
  • Heavy periods or low iron history
  • Vegetarian, vegan, restricted, or low-calorie diets
  • Chronic inflammation concerns
  • Joint pain, rashes, or autoimmune-type symptoms
  • Low libido, mood changes, or hormone concerns
  • Stress, burnout, or poor resilience
  • Statin use or muscle symptoms
  • Numbness, tingling, or neurologic-type symptoms
  • Interest in a broad fatigue and brain fog baseline

What This Panel Helps Evaluate

This panel helps evaluate selected biomarkers related to:

  • Fatigue and low energy
  • Brain fog and cognitive wellness
  • Blood health and oxygen delivery
  • Iron storage and iron transport
  • Thyroid hormone production, thyroid activity, and thyroid autoimmunity
  • Blood sugar, insulin, and metabolic flexibility
  • Inflammation and autoimmune screening
  • Cortisol, DHEA-S, pregnenolone, testosterone, estradiol, and hormone balance
  • B-vitamin and methylation patterns
  • Magnesium, zinc, selenium, vitamin D, and nutrient support
  • Kidney filtration and urine albumin patterns
  • Muscle enzyme activity
  • Omega fatty acid status
  • Mitochondrial energy support
  • General metabolic wellness

Which Tier Is Right for Me?

Essential Lab Panel

The Fatigue, Low Energy & Brain Fog Essential Lab Panel is best for people who want a focused starting point. It reviews the most common lab areas related to fatigue, including blood count, iron status, thyroid screening, blood sugar, vitamin D, B12/folate, magnesium, inflammation, CMP, and urinalysis.

Choose Essential if you want a practical first step for fatigue, low energy, or brain fog.

Advanced Lab Panel

The Fatigue, Low Energy & Brain Fog Advanced Lab Panel is best for people who want deeper insight into thyroid hormones, thyroid antibodies, insulin resistance, inflammation, muscle enzymes, cortisol, DHEA-S, testosterone, estradiol, methylation, functional B12, zinc, selenium, and RBC magnesium.

Choose Advanced if symptoms are persistent, recurring, or involve energy crashes, thyroid symptoms, hormone concerns, muscle weakness, or brain fog.

Comprehensive Lab Panel

The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel is the broadest option. It includes the Essential and Advanced categories and adds deeper kidney/urine markers, autoimmune screening with ANA, CoQ10, OMEGACHECK™, pregnenolone, Reverse T3, and expanded nutrient and mitochondrial support markers.

Choose Comprehensive if you want the broadest review of fatigue, brain fog, thyroid, hormones, inflammation, nutrients, kidney function, autoimmune patterns, and energy production.


Tests Included and Why They Matter

Blood Health, Oxygen Delivery & Iron Status

Fatigue often overlaps with blood count patterns, anemia, iron deficiency, low iron stores, and reduced oxygen delivery. This group helps evaluate whether the body has the blood and iron support needed for energy, stamina, mental clarity, and physical performance.

CBC, includes Differential and Platelets

The CBC evaluates red blood cells, white blood cells, hemoglobin, hematocrit, platelets, and white blood cell types.

This test is included because red blood cells and hemoglobin help carry oxygen throughout the body. Low hemoglobin, low hematocrit, anemia-related patterns, infection clues, immune changes, or platelet abnormalities may contribute to fatigue, weakness, dizziness, shortness of breath with exertion, low stamina, or poor recovery.

Ferritin

Ferritin measures stored iron.

This test is included because low iron stores may contribute to fatigue, low energy, low stamina, restless legs, hair shedding, heavy period-related symptoms, weakness, or poor exercise tolerance. Ferritin can also rise with inflammation, liver stress, metabolic issues, or iron overload, so it should be interpreted with iron/TIBC, CBC, hs-CRP, ESR, and symptoms.

Iron and Total Iron Binding Capacity, TIBC

Iron and TIBC help evaluate circulating iron and iron transport capacity.

This test is included because ferritin alone does not fully show iron availability. Iron/TIBC provides additional context for iron deficiency, iron overload, anemia-related patterns, oxygen delivery, fatigue, and weakness.


Thyroid Function, Thyroid Activity & Autoimmune Thyroid Patterns

Thyroid hormones help regulate metabolism, energy production, body temperature, mood, bowel function, hair and skin health, and cognitive speed. Thyroid symptoms can overlap strongly with fatigue and brain fog.

TSH

TSH is a key thyroid screening marker.

This test is included because thyroid function may influence energy, weight, metabolism, mood, body temperature, constipation, hair changes, and mental clarity. TSH provides an important starting point for thyroid-related fatigue review.

T4, Free

Free T4 measures the available form of thyroxine, a thyroid hormone.

This test is included because Free T4 provides additional thyroid hormone production context when reviewed with TSH and symptoms. It may be useful when fatigue, cold intolerance, weight changes, constipation, or low energy suggest possible thyroid involvement.

T3, Free

Free T3 measures the active form of thyroid hormone available in the bloodstream.

This test is included because T3 is closely tied to energy output, metabolism, body temperature, and mental alertness. Free T3 may provide added context when fatigue, brain fog, low metabolism, restrictive dieting, or stress patterns are present.

T3 Reverse, RT3, LC/MS/MS

Reverse T3 is an inactive thyroid hormone metabolite.

This test is included as a deeper thyroid-context marker for people with persistent fatigue, low energy, or brain fog when broader thyroid interpretation is desired. Reverse T3 should not be interpreted alone and is best reviewed with TSH, Free T4, Free T3, symptoms, nutrition status, stress, illness, and provider guidance.

Thyroid Peroxidase and Thyroglobulin Antibodies

These antibodies help evaluate autoimmune thyroid patterns.

This test is included because autoimmune thyroid activity may contribute to thyroid dysfunction and symptoms such as fatigue, brain fog, weight changes, hair shedding, mood changes, and cold intolerance. Including thyroid antibodies adds important context beyond thyroid hormone levels alone.


Blood Sugar, Insulin & Metabolic Energy

Energy crashes, cravings, sleepiness after meals, poor focus, weight changes, and fatigue may overlap with blood sugar and insulin patterns. This group helps evaluate metabolic flexibility and longer-term glucose regulation.

Hemoglobin A1c

Hemoglobin A1c measures average blood sugar over approximately the past two to three months.

This test is included because blood sugar patterns may affect energy, focus, cravings, mood, and metabolic wellness. A1c provides a longer-term view of glucose trends and may help support discussions about prediabetes, diabetes risk, and metabolic fatigue.

Insulin

Insulin helps move glucose from the bloodstream into cells.

This test is included because fasting insulin may provide context for insulin resistance, energy crashes, cravings, weight changes, and metabolic fatigue. Insulin may reveal metabolic strain even when glucose or A1c appear less obvious.

Lipid Panel

The Lipid Panel measures total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides.

This test is included because lipid patterns provide cardiometabolic context that may overlap with fatigue, insulin resistance, inflammation, weight changes, and metabolic wellness.


Inflammation, Autoimmune Screening & Immune Context

Inflammation and autoimmune patterns can contribute to fatigue, brain fog, body aches, joint pain, poor recovery, and low energy. This group helps evaluate low-grade inflammation, broader systemic inflammation, and autoimmune screening context.

hs-CRP

High-sensitivity C-reactive protein is a marker of low-grade inflammation.

This test is included because inflammation may contribute to fatigue, brain fog, metabolic stress, cardiovascular risk, and poor recovery. hs-CRP also helps interpret ferritin, which may rise with inflammation.

Sed Rate by Modified Westergren, ESR

ESR is a general inflammation marker.

This test is included because it provides a broader inflammation perspective that complements hs-CRP. ESR may be useful when fatigue overlaps with body aches, joint pain, chronic pain, inflammatory symptoms, or unexplained systemic concerns.

ANA Screen, IFA with Reflex to Titer and Pattern, IFA

ANA screening helps evaluate whether antinuclear antibodies are present.

This test is included because autoimmune patterns may overlap with fatigue, brain fog, joint pain, rashes, chronic pain, inflammation, and systemic symptoms. A positive ANA does not diagnose autoimmune disease by itself, but it may help guide provider-directed follow-up when symptoms suggest autoimmune involvement.


Adrenal, Stress & Hormone Balance

Stress hormones and sex hormones may influence energy, mood, motivation, sleep, libido, body composition, resilience, and recovery. This group helps provide context when fatigue overlaps with burnout, hormone changes, low libido, poor recovery, or stress-related symptoms.

Cortisol, A.M.

Morning cortisol helps evaluate cortisol levels during the time of day when cortisol is commonly expected to be higher.

This test is included because cortisol may provide context for stress response, sleep-wake rhythm, fatigue, burnout, blood sugar regulation, and recovery. Cortisol can be affected by sleep, stress, illness, caffeine, medications, and timing of collection.

DHEA Sulfate, Immunoassay

DHEA-S is an adrenal androgen marker.

This test is included because DHEA-S may provide context for adrenal hormone patterns, stress physiology, recovery, aging-related hormone changes, low resilience, and energy.

Pregnenolone, LC/MS/MS

Pregnenolone is a steroid hormone precursor.

This test is included because it may provide deeper context for adrenal and sex hormone pathways, stress physiology, and hormone balance. Pregnenolone is a premium marker best interpreted with cortisol, DHEA-S, sex hormones, symptoms, and provider guidance.

Testosterone, Total and Free and Sex Hormone Binding Globulin

This test evaluates total testosterone, free testosterone, and SHBG.

This test is included because testosterone availability may influence energy, libido, mood, motivation, muscle mass, body composition, strength, and recovery in both men and women. SHBG helps interpret how much testosterone is available for use by the body.

Estradiol

Estradiol is a major form of estrogen.

This test is included because estradiol may provide context for energy, mood, sleep, brain fog, menstrual changes, perimenopause, menopause, libido, bone health, and hormone balance. Interpretation should consider sex, age, cycle timing, menopause status, hormone therapy, and symptoms.


B Vitamins, Methylation & Brain Fog Support

B vitamins and methylation-related markers are important for red blood cell production, nerve function, DNA synthesis, neurotransmitter pathways, and cognitive wellness. This group is especially relevant when fatigue overlaps with brain fog, numbness, tingling, mood changes, or restricted diets.

Vitamin B12 and Folate Panel, Serum

This panel measures vitamin B12 and folate.

These nutrients support red blood cell production, nerve function, DNA synthesis, methylation, and general wellness. This test is included because B12 and folate status may provide context for fatigue, brain fog, weakness, numbness, tingling, anemia-related patterns, and cognitive concerns.

Methylmalonic Acid

Methylmalonic acid, or MMA, is a functional marker related to vitamin B12 status.

This test is included because MMA may help identify functional B12 insufficiency when serum B12 is borderline or when symptoms suggest B12-related issues. It is especially useful for brain fog, numbness, tingling, fatigue, weakness, or neurologic-type symptoms.

Homocysteine

Homocysteine is influenced by vitamin B12, folate, vitamin B6, methylation pathways, kidney function, and vascular health.

This test is included because it provides functional context for B-vitamin status, methylation, vascular wellness, and brain fog-related discussions.

Vitamin B6, Pyridoxal Phosphate

Vitamin B6 is involved in neurotransmitter pathways, methylation, amino acid metabolism, immune function, and nervous system health.

This test is included because B6 may provide context for mood, energy, neurologic symptoms, methylation support, and supplement safety.


Minerals, Nutrients, Omega Fatty Acids & Mitochondrial Energy

Nutrient status can influence energy production, cognition, muscle function, immune resilience, thyroid activity, inflammation, and recovery. This group evaluates key nutrients and energy-support markers.

Magnesium

Magnesium supports muscle function, nerve signaling, sleep, glucose metabolism, blood pressure regulation, and energy production.

This test is included because magnesium may provide context for fatigue, muscle cramps, sleep quality, anxiety-like symptoms, blood sugar patterns, and nervous system function.

Magnesium, RBC

RBC magnesium may provide additional magnesium status context compared with serum magnesium alone.

This test is included because deeper magnesium evaluation may be useful when fatigue, poor sleep, cramps, muscle symptoms, or nervous system symptoms are present.

QuestAssureD™ 25-Hydroxyvitamin D, D2, D3, LC/MS/MS

Vitamin D testing measures vitamin D status.

This test is included because vitamin D supports bone health, immune function, muscle function, inflammation balance, mood, and general wellness. Low vitamin D status may overlap with fatigue, muscle aches, and low resilience.

Zinc

Zinc supports immune function, wound healing, thyroid pathways, hormone balance, antioxidant activity, taste and smell, and tissue repair.

This test is included because zinc may provide context for immune resilience, thyroid wellness, fatigue, nutrient status, and hormone-related patterns.

Selenium

Selenium supports antioxidant enzymes and thyroid-related pathways.

This test is included because selenium may provide useful context for thyroid support, oxidative stress, immune function, and general fatigue review.

OMEGACHECK™

OMEGACHECK™ evaluates omega fatty acid status.

This test is included because omega-3 and omega-6 fatty acid patterns may provide context for inflammation balance, cardiovascular wellness, nutrition quality, brain health, and recovery.

Coenzyme Q10

Coenzyme Q10 is involved in mitochondrial energy production and antioxidant support.

This test is included because CoQ10 may provide context for cellular energy production, fatigue, statin use, muscle symptoms, and mitochondrial wellness.


Kidney, Urine & Muscle Stress Context

Kidney function, urine findings, and muscle enzymes can contribute to fatigue, weakness, and poor recovery. This group adds deeper safety and performance context.

Comprehensive Metabolic Panel, CMP

The CMP evaluates glucose, liver function, kidney function, electrolytes, calcium, albumin, total protein, and metabolic markers.

This test is included because fatigue review benefits from a broad organ-function baseline. CMP findings may provide context for hydration, electrolytes, glucose, liver enzymes, kidney markers, calcium, protein status, and metabolic wellness.

Cystatin C with eGFR

Cystatin C with eGFR provides an additional estimate of kidney filtration.

This test is included because kidney function can affect fatigue, medication clearance, metabolic waste handling, and interpretation of other markers. Cystatin C adds kidney filtration context beyond creatinine alone.

Albumin, Random Urine with Creatinine

This urine test evaluates albumin relative to creatinine.

It is included because urine albumin may provide early kidney and vascular stress context, especially when fatigue overlaps with diabetes risk, hypertension, metabolic concerns, or kidney-related issues.

Urinalysis, UA, Complete

A complete urinalysis evaluates urine markers such as protein, blood, glucose, ketones, specific gravity, pH, and other findings.

This test is included because urine findings may provide context for hydration, kidney health, urinary findings, glucose handling, ketones, protein, and blood in urine.

Creatine Kinase, CK, Total

CK is an enzyme found mainly in muscle tissue.

This test is included because CK may provide context for muscle fatigue, weakness, statin-related muscle symptoms, intense exercise, muscle inflammation, or muscle breakdown. CK can also help clarify whether AST or ALT elevations from the CMP may be muscle-related.


Related Biomarker Patterns This Panel May Help Identify

This panel may help identify or rule out lab patterns related to:

  • Anemia or blood count abnormalities
  • Low iron stores or abnormal iron availability
  • Thyroid dysfunction or autoimmune thyroid patterns
  • Blood sugar imbalance or insulin resistance
  • Low-grade or systemic inflammation
  • Autoimmune screening patterns
  • Cortisol, DHEA-S, pregnenolone, testosterone, or estradiol patterns
  • Low B12, folate, B6, or functional B12 concerns
  • Methylation and homocysteine patterns
  • Low magnesium or RBC magnesium status
  • Low vitamin D, zinc, or selenium status
  • Omega fatty acid patterns
  • CoQ10 and mitochondrial energy context
  • Kidney filtration or urine albumin patterns
  • Urinalysis abnormalities
  • Muscle enzyme elevations

Professional Safety and Interpretation Notice

This panel is designed to support fatigue, low energy, and brain fog evaluation. It does not diagnose the cause of fatigue, cognitive symptoms, thyroid disease, autoimmune disease, hormone imbalance, adrenal dysfunction, or any condition by itself. Results should be interpreted with a licensed healthcare provider and reviewed alongside symptoms, sleep, stress, diet, medications, supplements, exercise, menstrual status, age, sex, medical history, and health goals.

Do not stop or change any prescribed medication or supplement without guidance from your healthcare provider.


How to Prepare for This Panel

Preparation may vary depending on the specific tests and instructions provided with your order. In general:

  • Fasting may be recommended because glucose, insulin, and lipid markers are included.
  • Morning collection may be preferred for cortisol and testosterone.
  • Avoid unusually intense exercise before testing if baseline CK and inflammation markers are desired.
  • Bring a list of medications, supplements, hormone products, thyroid medications, and doses.
  • Note symptoms such as fatigue, brain fog, sleep changes, stress, mood changes, muscle weakness, pain, or numbness/tingling.
  • For women, note menstrual cycle timing, menopause status, hormone therapy, and bleeding patterns.
  • Drink water normally unless instructed otherwise.
  • Follow all lab collection instructions provided with your order.

What Happens After You Receive Your Results?

After your results are available, your biomarkers can help organize fatigue and brain fog findings into areas such as blood health, iron status, thyroid function, inflammation, autoimmune screening, blood sugar, insulin resistance, stress hormones, sex hormones, B-vitamin status, methylation, mineral balance, omega fatty acids, mitochondrial support, kidney function, urine health, and muscle enzymes.

During the physician consultation, you can discuss whether your results suggest the need for follow-up testing, medication review, nutrition changes, hormone review, thyroid review, lifestyle changes, sleep evaluation, or additional clinical care.


Additional Panels to Consider

Customers interested in the Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel may also consider:

  • Fatigue, Low Energy & Brain Fog Essential Lab Panel
  • Fatigue, Low Energy & Brain Fog Advanced Lab Panel
  • Thyroid & Metabolism Lab Panel
  • Stress, Cortisol, Sleep & Burnout Lab Panel
  • Vitamin, Mineral & Nutrient Deficiency Lab Panel
  • Inflammation, Autoimmune & Chronic Pain Lab Panel
  • Prediabetes & Insulin Resistance Lab Panel
  • Women’s Hormone Balance & Perimenopause Lab Panel
  • Men’s Testosterone, Energy & Vitality Lab Panel
  • Medication & Supplement Safety Lab Panel
  • Heavy Metals & Environmental Toxins Lab Panel
  • Longevity & Healthy Aging Lab Panel

FAQ: Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel

What is the Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel?

The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel is a broad blood and urine test panel that evaluates biomarkers related to anemia, iron status, thyroid function, inflammation, autoimmune screening, blood sugar, insulin resistance, hormones, adrenal stress, nutrients, methylation, kidney function, urine health, muscle enzymes, omega fatty acids, and mitochondrial energy support.

What blood tests are commonly reviewed for fatigue?

Common fatigue-related blood tests may include CBC, CMP, ferritin, iron/TIBC, TSH, Free T4, vitamin B12, folate, vitamin D, magnesium, A1c, inflammation markers, and thyroid antibodies. This Comprehensive panel expands beyond those basics with insulin, Free T3, Reverse T3, ANA, cortisol, DHEA-S, testosterone, estradiol, CoQ10, OMEGACHECK™, MMA, homocysteine, zinc, selenium, cystatin C, and urinalysis.

Does this panel help evaluate brain fog?

This panel includes markers that may be useful when brain fog overlaps with B12 or folate concerns, thyroid patterns, blood sugar imbalance, inflammation, hormone changes, sleep-stress patterns, omega fatty acid status, kidney function, or nutrient deficiencies. It does not diagnose the cause of brain fog by itself.

Why are thyroid markers included?

Thyroid function can affect energy, metabolism, mood, focus, weight, body temperature, hair, skin, and bowel patterns. This panel includes TSH, Free T4, Free T3, Reverse T3, and thyroid antibodies for a deeper thyroid review.

Why are ferritin and iron/TIBC included?

Ferritin measures stored iron, while iron/TIBC evaluates circulating iron and iron transport. Iron status may provide useful context for fatigue, weakness, low stamina, heavy periods, restless legs, dizziness, and anemia-related patterns.

Why are B12, folate, MMA, homocysteine, and B6 included?

These markers help evaluate B-vitamin status, methylation, red blood cell production, nerve function, and brain fog-related nutrient patterns. MMA adds functional B12 context, while homocysteine can reflect B-vitamin and methylation-related patterns.

Why are cortisol, DHEA-S, and pregnenolone included?

These markers provide stress-hormone and adrenal pathway context. They may be useful when fatigue overlaps with burnout, poor resilience, poor recovery, sleep-wake issues, low motivation, or stress-related symptoms.

Why are testosterone and estradiol included?

Testosterone and estradiol may provide hormone-balance context for energy, mood, libido, sleep, body composition, strength, motivation, and perimenopause, menopause, or low-testosterone concerns.

Why are inflammation and autoimmune markers included?

hs-CRP and ESR provide inflammation context, while ANA screening may help identify autoimmune patterns that may require provider-guided follow-up when fatigue overlaps with joint pain, rashes, chronic pain, or systemic symptoms.

Why is CoQ10 included?

CoQ10 supports mitochondrial energy production and antioxidant function. It may provide context for fatigue, muscle symptoms, statin use, or energy-production concerns.

Can this panel diagnose chronic fatigue syndrome?

No. This panel does not diagnose chronic fatigue syndrome, ME/CFS, autoimmune disease, thyroid disease, adrenal disease, or any condition by itself. It helps evaluate selected biomarkers that may be useful to review with a licensed healthcare provider.

Should I choose Essential, Advanced, or Comprehensive?

Choose Essential for a focused fatigue baseline, Advanced for deeper thyroid, metabolic, hormone, inflammation, and nutrient testing, and Comprehensive for the broadest review of fatigue, brain fog, autoimmune, kidney, hormone, methylation, omega, and mitochondrial markers.


Important Note

This panel is designed to help evaluate selected biomarkers that may be related to fatigue, low energy, brain fog, thyroid function, iron status, inflammation, blood sugar, hormones, adrenal stress, nutrient status, kidney function, urine health, omega fatty acid status, and mitochondrial energy support. It is not intended to diagnose, treat, cure, or prevent disease by itself. Results should be reviewed with a licensed healthcare provider.

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