Fatigue, Low Energy & Brain Fog - Comprehensive Lab Panel
A comprehensive fatigue lab panel for people with persistent low energy, brain fog, poor stamina, or unexplained tiredness. This panel evaluates a broad range of biomarkers, including thyroid function, thyroid antibodies, iron status, vitamins, inflammation, cortisol, hormones, insulin resistance, autoimmune screening, muscle enzymes, urinalysis, liver function, kidney function, and metabolic health.
- $2,843.16
- $598.95
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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
Also known as: ANA, ANA Screen IFA with Reflex to Titer and Pattern IFA, ANA with Reflux
ANA Screen, IFA
Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)
NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.
Absolute Band Neutrophils (Only Reported If Detected)
Absolute Basophils
Absolute Blasts (Only Reported If Detected)
Absolute Eosinophils
Absolute Lymphocytes
Absolute Metamyelocytes (Only Reported If Detected)
Absolute Monocytes
Absolute Myelocytes (Only Reported If Detected)
Absolute Neutrophils
Absolute Nucleated Rbc (Only Reported If Detected)
Absolute Promyelocytes (Only Reported If Detected)
Band Neutrophils (Only Reported If Detected)
Basophils
Blasts (Only Reported If Detected)
Eosinophils
Hematocrit
Hemoglobin
Lymphocytes
MCH
MCHC
MCV
Metamyelocytes (Only Reported If Detected)
Monocytes
MPV
Myelocytes (Only Reported If Detected)
Neutrophils
Nucleated Rbc (Only Reported If Detected)
Platelet Count
Promyelocytes (Only Reported If Detected)
RDW
Reactive Lymphocytes (Only Reported If Detected)
Red Blood Cell Count
White Blood Cell Count
Also known as: CoQ10
Coenzyme Q10
Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20
Albumin
Albumin/Globulin Ratio
Alkaline Phosphatase
Alt
AST
Bilirubin, Total
Bun/Creatinine Ratio
Calcium
Carbon Dioxide
Chloride
Creatinine
Egfr African American
Egfr Non-Afr. American
GFR-AFRICAN AMERICAN
GFR-NON AFRICAN AMERICAN
Globulin
Glucose
Potassium
Protein, Total
Sodium
Urea Nitrogen (Bun)
Also known as: Cortisol AM
Cortisol, A.M.
Also known as: CK (Total), CPK, CPK (Total), Creatine Kinase CK Total, Creatine Phosphokinase (CPK), Total CK
Creatine Kinase, Total
Also known as: Dehydroepiandrosterone Sulfate, DHEA SO4, DHEA Sulfate Immunoassay, DHEAS, Transdehydroandrosterone
DHEA SULFATE
Estradiol
Ferritin
Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c
HEMOGLOBIN A1C
Also known as: Homocysteine, Homocysteine Cardiovascular
HOMOCYSTEINE,
Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP
Hs Crp
Also known as: Insulin (fasting)
Insulin
Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC
% Saturation
Iron Binding Capacity
Iron, Total
Also known as: Cholesterol, HDL,Fasting Lipids,Cholesterol, LDL, Fasting Lipids, Lipid Panel (fasting), Lipid Profile (fasting), Lipids
Chol/HDLC Ratio
Cholesterol, Total
HDL Cholesterol
LDL-Cholesterol
Non HDL Cholesterol
Triglycerides
Magnesium
Vitamin D, 25-Oh, D2
Vitamin D, 25-Oh, D3
Vitamin D, 25-Oh, Total
Also known as: ESR, SED RATE, Sed Rate by Modified Westergren ESR
Sed Rate By Modified
Also known as: Free T3, FT3, T3 Free
T3, Free
Also known as: Free T4, FT4, T4 Free
T4, Free
Also known as: Testosterone Total And Free And Sex Hormone Binding Globulin
Free Testosterone
Sex Hormone Binding
TESTOSTERONE, TOTAL,
Thyroglobulin Antibodies
Thyroid Peroxidase
Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test
TSH
Also known as: UA, Complete, Urinalysis UA Complete, Urine Analysis, Complete
Amorphous Sediment (Only Reported If Detected)
Appearance
Bacteria
Bilirubin
Calcium Oxalate Crystals (Only Reported If Detected)
Casts (Only Reported If Detected)
Color
Crystals (Only Reported If Detected)
Glucose
Granular Cast (Only Reported If Detected)
Hyaline Cast
Ketones
Leukocyte Esterase
Nitrite
Occult Blood
Ph
Protein
Rbc
Reducing Substances (Only Reported If Detected)
Renal Epithelial Cells (Only Reported If Detected)
Specific Gravity
Squamous Epithelial Cells
Transitional Epithelial (Only Reported If Detected)
Triple Phosphate Crystals (Only Reported If Detected)
Uric Acid Crystals (Only Reported If Detected)
WBC
YEAST (Only Reported If Detected)
Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid
Folate, Serum
Vitamin B12
The Fatigue, Low Energy & Brain Fog - Comprehensive Lab Panel panel contains 25 tests with 116 biomarkers .
Overview
The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel is the most complete option in this panel group. It includes the core and advanced fatigue-related markers, plus additional testing related to inflammation, autoimmune screening, stress hormones, sex hormones, thyroid antibodies, muscle enzymes, urinalysis, and nutrient-related pathways.
This panel is designed for people who want a more complete lab review of possible patterns related to persistent fatigue, low energy, poor focus, brain fog, low stamina, weakness, poor recovery, and feeling unwell.
The Comprehensive panel may be especially helpful for people with multiple symptoms, ongoing fatigue, possible thyroid concerns, possible hormone-related symptoms, inflammatory symptoms, stress-related fatigue, or unexplained low energy.
Why Order This Panel?
Fatigue, low energy, and brain fog can involve several overlapping systems, including thyroid function, nutrients, blood sugar, inflammation, hormones, cortisol, autoimmune activity, liver function, kidney function, and muscle recovery.
The Comprehensive panel is designed to provide the broadest fatigue-related lab review in this panel group. It may help you and your healthcare provider identify patterns that were not captured by more basic testing, especially when symptoms are persistent, complex, or unexplained.
This Panel May Be Helpful For People Experiencing
- Persistent fatigue
- Low energy despite sleep
- Brain fog or poor mental clarity
- Low stamina or poor recovery
- Muscle weakness or soreness
- Stress-related fatigue
- Possible thyroid symptoms
- Possible hormone-related symptoms
- Unexplained inflammation
- Joint aches or body aches
- Hair thinning or shedding
- Energy crashes
- Feeling run down without a clear reason
- Multiple symptoms that have not been explained
Common Symptoms This Panel May Help Evaluate
This panel may be helpful for people experiencing:
- Fatigue or low energy
- Brain fog or poor focus
- Feeling tired after a full night of sleep
- Afternoon energy crashes
- Weakness or low stamina
- Poor exercise recovery
- Dizziness or lightheadedness
- Hair shedding or brittle nails
- Cold intolerance
- Mood changes
- Sleep disruption
- Sugar cravings
- Muscle aches or soreness
- Joint aches or body aches
- Feeling run down or depleted
What This Panel Helps Evaluate
This panel helps evaluate selected biomarkers related to:
- Blood cell health
- Anemia-related patterns
- Iron storage and iron availability
- Thyroid function
- Thyroid autoimmunity
- Blood sugar and insulin patterns
- Inflammation
- Autoimmune screening
- Cortisol and stress physiology
- DHEA-S and adrenal hormone context
- Testosterone, estradiol, and hormone availability
- Muscle enzyme activity
- Homocysteine and B-vitamin-related pathways
- Vitamin D, B12, folate, and magnesium status
- Liver and kidney function
- Urine health indicators
- Cardiometabolic health
What Makes This Comprehensive Panel Different?
The Comprehensive panel includes a broader set of biomarkers than the Essential and Advanced options. It is designed for people who want a deeper look at possible fatigue-related patterns, including thyroid function, thyroid antibodies, inflammation, autoimmune screening, blood sugar and insulin patterns, hormone balance, cortisol, nutrient status, urinalysis, and muscle enzyme activity.
This makes it a strong option for people with persistent fatigue, multiple symptoms, hormone-related concerns, inflammatory symptoms, possible autoimmune concerns, or prior basic labs that did not provide enough insight.
Which Tier Is Right for Me?
| Choose This Tier | Best For |
|---|---|
| Essential | A focused starting point for fatigue, low energy, brain fog, thyroid screening, blood sugar, vitamin D, B12, and iron storage |
| Advanced | A deeper review that adds thyroid hormones, inflammation, insulin, magnesium, lipids, iron/TIBC, and folate |
| Comprehensive | The most complete option, adding thyroid antibodies, autoimmune screening, cortisol, DHEA-S, sex hormones, CK, homocysteine, CoQ10, ESR, and urinalysis |
Tests Included and Why They Matter
ANA Screen, IFA with Reflex to Titer and Pattern, IFA
ANA screening helps evaluate whether antinuclear antibodies are present. This test is included because certain autoimmune patterns may be associated with fatigue, joint pain, rashes, inflammation, body aches, or other systemic symptoms. A positive ANA does not diagnose an autoimmune disease by itself, but it may help guide physician review and possible follow-up testing.
CBC, includes Differential and Platelets
The CBC evaluates red blood cells, white blood cells, hemoglobin, hematocrit, platelets, and white blood cell types. This test is included because anemia, infection patterns, immune changes, inflammation clues, or platelet abnormalities may contribute to fatigue, weakness, or feeling unwell.
Coenzyme Q10
Coenzyme Q10 is involved in cellular energy production and mitochondrial function. This test is included because CoQ10 status may be relevant for people with fatigue, muscle symptoms, statin use, or interest in energy metabolism. It may help provide additional context in a comprehensive fatigue and wellness review.
Comprehensive Metabolic Panel, CMP
The CMP evaluates liver function, kidney function, electrolytes, glucose, calcium, protein, and other metabolic markers. This test is included because fatigue and brain fog may be influenced by blood sugar patterns, electrolyte imbalance, dehydration, kidney function, liver enzyme changes, or abnormal protein levels.
Cortisol, A.M.
Morning cortisol helps evaluate cortisol levels during the time of day when cortisol is commonly expected to be higher. This test is included because cortisol is involved in stress response, energy regulation, blood pressure support, and sleep-wake rhythm. Abnormal cortisol patterns may be useful to review with a healthcare provider when symptoms include fatigue, weakness, stress, poor sleep, or energy crashes.
Creatine Kinase, CK, Total
Creatine kinase is an enzyme found mainly in skeletal muscle, heart muscle, and brain tissue. This test is included because elevated CK may be associated with muscle injury, intense exercise, muscle inflammation, medication effects, or other muscle-related concerns that may contribute to weakness, soreness, or poor recovery.
DHEA Sulfate, Immunoassay
DHEA-S is an adrenal hormone that serves as a marker of adrenal androgen production. This test is included because DHEA-S may provide context for energy, stress response, hormone balance, libido, mood, and aging-related hormone patterns.
Estradiol
Estradiol is a major form of estrogen. This test is included because estrogen status may influence energy, sleep, mood, cognition, body composition, bone health, and hormone balance. Estradiol may be relevant for both women and men when interpreting fatigue, low energy, or hormone-related symptoms.
Ferritin
Ferritin measures stored iron. This test is included because low iron stores may contribute to fatigue, weakness, low stamina, dizziness, shortness of breath with activity, hair shedding, and poor exercise tolerance. Ferritin also provides important context when reviewed with iron and TIBC.
Hemoglobin A1c
Hemoglobin A1c measures average blood sugar over approximately two to three months. This test is included because blood sugar imbalance, prediabetes, diabetes, or frequent glucose swings may contribute to fatigue, brain fog, cravings, and energy crashes.
Homocysteine
Homocysteine is an amino acid that may be influenced by vitamin B12, folate, vitamin B6, methylation pathways, kidney function, and cardiovascular health. This test is included because elevated homocysteine may provide additional context for B-vitamin status, vascular health, and metabolic wellness.
hs-CRP
High-sensitivity C-reactive protein is a marker of inflammation. This test is included because inflammation may contribute to fatigue, low energy, body aches, and cardiometabolic risk patterns. hs-CRP may be especially useful when reviewed with lipid, glucose, insulin, and other metabolic markers.
Insulin
Insulin helps regulate blood sugar by moving glucose from the bloodstream into cells. This test is included because elevated fasting insulin may suggest insulin resistance before blood sugar or A1c becomes clearly abnormal. Insulin resistance may be associated with fatigue, weight gain, cravings, energy crashes, and metabolic health concerns.
Iron and Total Iron Binding Capacity, TIBC
Iron and TIBC help evaluate circulating iron and iron transport capacity. This test is included because iron deficiency, poor iron availability, or abnormal iron patterns may contribute to fatigue, weakness, poor stamina, dizziness, and shortness of breath with activity.
Lipid Panel
The lipid panel evaluates total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides. This test is included because cholesterol and triglyceride patterns provide important cardiometabolic context. Triglycerides and HDL may also help identify metabolic patterns that can overlap with fatigue, blood sugar imbalance, and insulin resistance.
Magnesium
Magnesium is involved in muscle function, nerve signaling, glucose metabolism, sleep, heart rhythm, and energy production. This test is included because low or suboptimal magnesium may be associated with muscle cramps, fatigue, headaches, poor sleep, weakness, or metabolic concerns.
QuestAssureD™ 25-Hydroxyvitamin D, D2, D3, LC/MS/MS
Vitamin D testing measures vitamin D status. This test is included because low vitamin D is common and may be associated with fatigue, muscle aches, low mood, immune concerns, bone health concerns, and general wellness issues. The QuestAssureD™ method provides detailed vitamin D measurement.
Sed Rate by Modified Westergren, ESR
ESR, or erythrocyte sedimentation rate, is a general marker of inflammation. This test is included because elevated ESR may suggest an inflammatory pattern that should be reviewed with a healthcare provider, especially when symptoms include fatigue, joint pain, body aches, fever, or unexplained illness.
T3, Free
Free T3 measures the active form of thyroid hormone available in the bloodstream. This test is included because thyroid hormone activity may affect energy, metabolism, body temperature, mood, bowel function, and mental clarity.
T4, Free
Free T4 measures the available storage form of thyroid hormone. This test is included because Free T4 provides additional thyroid context when reviewed with TSH and Free T3. Thyroid hormone imbalance may contribute to fatigue, brain fog, weight changes, cold intolerance, and changes in mood or energy.
Testosterone, Total and Free and Sex Hormone Binding Globulin
This test evaluates total testosterone, free testosterone, and SHBG, which helps determine how much testosterone is available for use by the body. This test is included because testosterone availability may influence energy, strength, motivation, libido, mood, body composition, and recovery in both men and women.
Thyroid Peroxidase and Thyroglobulin Antibodies
These antibodies help evaluate autoimmune thyroid patterns. This test is included because autoimmune thyroid conditions may contribute to fatigue, brain fog, weight changes, hair thinning, cold intolerance, mood changes, and thyroid hormone changes. Antibodies can sometimes be present before major changes appear in TSH.
TSH
TSH is a key thyroid screening marker. This test is included because thyroid dysfunction may contribute to fatigue, brain fog, cold intolerance, weight changes, constipation, low mood, hair thinning, and changes in heart rate or energy level.
Urinalysis, UA, Complete
A complete urinalysis evaluates urine markers such as protein, glucose, ketones, blood, specific gravity, pH, and other urine findings. This test is included because urine results may provide clues related to hydration, kidney function, glucose handling, infection patterns, or other health concerns that may contribute to fatigue or feeling unwell.
Vitamin B12 and Folate Panel, Serum
This panel measures vitamin B12 and folate. These nutrients are important for red blood cell formation, nerve function, DNA synthesis, methylation, and brain health. This test is included because low B12 or folate may contribute to fatigue, brain fog, weakness, numbness or tingling, mood changes, and anemia-related patterns.
Related Biomarker Patterns This Panel May Help Identify
This panel may help identify or rule out lab patterns related to:
- Anemia or abnormal blood count patterns
- Low iron stores
- Poor iron availability
- Low vitamin B12 or folate
- Low vitamin D
- Thyroid imbalance
- Autoimmune thyroid patterns
- Blood sugar imbalance
- Insulin resistance
- Inflammation
- Autoimmune screening patterns
- Stress hormone patterns
- Hormone availability
- Muscle enzyme elevation
- Kidney or liver function changes
- Urinalysis abnormalities
- Cardiometabolic risk patterns
How to Prepare for This Panel
Preparation may vary depending on the specific tests included and the instructions provided at checkout. In general:
- Fasting may be recommended because this panel includes insulin, lipid panel, glucose-related markers, and metabolic testing.
- Morning collection may be preferred because this panel includes cortisol and testosterone-related testing.
- Drink water before your blood draw unless instructed otherwise.
- Avoid unusually intense exercise shortly before testing if creatine kinase is included, unless your healthcare provider advises otherwise.
- Continue medications unless your healthcare provider tells you otherwise.
- Bring or keep a list of medications and supplements to discuss during your physician consultation.
- Follow all lab collection instructions provided with your order.
What Happens After You Receive Your Results?
After your lab results are available, your report can help organize your biomarkers into easy-to-understand patterns. Your results may highlight areas to review with a licensed healthcare provider, such as thyroid function, thyroid antibodies, nutrient status, inflammation, blood sugar, insulin, hormones, cortisol, urinalysis findings, or metabolic health.
During the physician consultation, you can discuss what your results may mean, whether follow-up testing is appropriate, and what next steps may be useful based on your symptoms and health history.
Related Lab Panels
Customers interested in this panel may also consider:
- Thyroid & Metabolism Lab Panel
- Women’s Hormone Balance & Perimenopause Lab Panel
- Men’s Testosterone, Energy & Vitality Lab Panel
- Stress, Cortisol, Sleep & Burnout Lab Panel
- Inflammation, Autoimmune & Chronic Pain Lab Panel
- Vitamin, Mineral & Nutrient Deficiency Lab Panel
- Prediabetes & Insulin Resistance Lab Panel
Frequently Asked Questions
What is the Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel?
The Fatigue, Low Energy & Brain Fog Comprehensive Lab Panel is the most complete panel in this group. It includes a broad set of tests related to fatigue, brain fog, blood health, thyroid function, thyroid antibodies, inflammation, hormones, nutrients, insulin, cortisol, urinalysis, muscle enzymes, and metabolic health.
How is the Comprehensive panel different from the Advanced panel?
The Comprehensive panel includes all Advanced tests and adds ANA screening, ESR, cortisol AM, DHEA-S, estradiol, testosterone with SHBG, thyroid antibodies, homocysteine, Coenzyme Q10, creatine kinase, and urinalysis.
Does this panel diagnose chronic fatigue syndrome?
No. This panel does not diagnose chronic fatigue syndrome or any specific condition. It helps identify lab patterns that may be useful to discuss with a healthcare provider.
Does this panel include hormone testing?
Yes. It includes estradiol, DHEA-S, and testosterone testing with SHBG.
Does this panel include autoimmune screening?
Yes. It includes ANA screening and ESR, which may help identify patterns that warrant further physician review.
Does this panel include thyroid antibodies?
Yes. It includes thyroid peroxidase and thyroglobulin antibodies.
What blood tests are commonly ordered for fatigue?
Blood tests commonly used to evaluate fatigue may include CBC, CMP, TSH, Free T4, Free T3, ferritin, iron/TIBC, vitamin B12, folate, vitamin D, Hemoglobin A1c, insulin, inflammatory markers, and selected hormone tests.
Can low vitamin D cause fatigue?
Low vitamin D may be associated with fatigue, muscle aches, low mood, immune concerns, and bone health issues. Vitamin D testing can help determine whether your level is low, normal, or elevated.
Can low B12 cause brain fog?
Low vitamin B12 may contribute to fatigue, brain fog, numbness or tingling, weakness, mood changes, and memory or concentration concerns.
Can thyroid problems cause fatigue and brain fog?
Thyroid imbalance may contribute to fatigue, brain fog, weight changes, cold intolerance, constipation, hair thinning, low mood, and changes in heart rate or energy.
Why is ferritin included in a fatigue panel?
Ferritin measures stored iron. Low ferritin may contribute to fatigue, weakness, low stamina, dizziness, hair shedding, and reduced exercise tolerance.
Why is insulin included in the Comprehensive panel?
Insulin helps evaluate blood sugar regulation and possible insulin resistance. Insulin resistance may be associated with fatigue, cravings, energy crashes, weight gain, and metabolic health concerns.
Why are cortisol and DHEA-S included?
Cortisol and DHEA-S provide hormone-related context for stress response, energy regulation, and adrenal hormone patterns. These markers may be useful to discuss with a healthcare provider when fatigue overlaps with poor sleep, stress, weakness, or low resilience.
Why is creatine kinase included?
Creatine kinase may help evaluate muscle-related stress, injury, or inflammation. This can be useful when fatigue occurs with muscle soreness, weakness, intense exercise, or medication-related concerns.
Should I choose Essential, Advanced, or Comprehensive?
Choose Essential for a focused starting point, Advanced for a deeper fatigue and metabolism review, and Comprehensive for the broadest evaluation of fatigue-related biomarkers.
Important Note
This lab panel is designed to help evaluate selected biomarkers that may be related to fatigue, low energy, brain fog, thyroid function, hormone balance, inflammation, stress response, nutrient status, and metabolic wellness. It is not intended to diagnose, treat, cure, or prevent any disease. Results should be reviewed with a licensed healthcare provider, especially if symptoms are severe, persistent, new, or worsening.