Ulta Lab Tests

Estradiol and Testosterone Free and Total

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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Estradiol

Estradiol (estradiol-17 beta, E2) is part of an estrogen that is a group of steroids that regulate the menstrual cycle and function as the main female sex hormones. Estrogens are responsible for the development of female sex organs and secondary sex characteristics and are tied to the menstrual cycle and pregnancy. They are considered the main sex hormones in women and are present in small quantities in men. Estradiol (E2) is the predominant form of estrogen and is produced primarily in the ovaries with additional amounts produced by the adrenal glands in women and in the testes and adrenal glands in men. Estradiol levels are used in evaluating ovarian function. Estradiol levels are increased in cases of early (precocious) puberty in girls and gynecomastia in men. Its main use has been in the differential diagnosis of amenorrhea – for example, to determine whether the cause is menopause, pregnancy, or a medical problem. In assisted reproductive technology (ART), serial measurements are used to monitor follicle development in the ovary in the days prior to in vitro fertilization. Estradiol is also sometimes used to monitor menopausal hormone replacement therapy.

Also known as: Testosterone Free Dialysis and Total LCMSMS

Free Testosterone

In many cases, measurement of total testosterone provides the doctor with adequate information. However, in certain cases, for example when the level of SHBG is abnormal, a test for free or bioavailable testosterone may be performed as it may more accurately reflect the presence of a medical condition.

TESTOSTERONE, TOTAL,

A testosterone test measures the amount of the male hormone, testosterone, in the blood. Both men and women produce this hormone. In males, the testicles produce most of the testosterone in the body. Levels are most often checked to evaluate signs of low testosterone: In boys -- early or late puberty and in men -- impotence, low level of sexual interest, infertility, thinning of the bones In females, the ovaries produce most of the testosterone and levels are most often checked to evaluate signs of higher testosterone levels, such as: decreased breast size, excess hair growth, increased size of the clitoris. irregular or absent menstrual periods and male-pattern baldness or hair thinning.
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The Estradiol and Testosterone Free and Total panel contains 2 tests with 3 biomarkers .

Brief Description: The Estradiol and Testosterone Free and Total Panel is a specialized blood test that evaluates key hormones involved in reproductive health, sexual development, and overall well-being. This panel measures levels of estradiol, a primary form of estrogen, as well as both free and total testosterone, which are critical for understanding hormonal balance in both men and women. Hormonal imbalances can lead to a wide range of symptoms and health issues, making this panel an essential tool for diagnosing and managing conditions related to endocrine function. By assessing these hormones, healthcare professionals can gain valuable insights into a patient’s hormonal health and identify potential underlying causes of symptoms such as infertility, low libido, or abnormal menstrual cycles.

Estradiol and Testosterone Free and Total Adult Only Test | Ulta Lab Tests

Collection Method: Blood Draw Estradiol and Testosterone Free and Total Test Blood Draw | Ulta Lab Tests
Specimen Type: 2.8 mL Serum Estradiol and Testosterone Free and Total Test Specimen Type Serum Gel | Ulta Lab TestsEstradiol and Testosterone Free and Total Test Specimen Type Serum No Gel | Ulta Lab Tests

Test Preparation: No preparation required

Estradiol and Testosterone Free and Total Test Swap Test Swap

This panel is intended for patients that are 18 years old or older.

If this panel is ordered for a pediatric (under 18) patient, the lab will automatically change the Estradiol test code to and charge for Estradiol, Ultrasensitive LC/MS/MS #30289.

For male patients with low estradiol levels, the lab may change the Estradiol test to and charge for Estradiol, Ultrasensitive LC/MS/MS #30289.

When and Why the Estradiol and Testosterone Free and Total Panel May Be Ordered

The Estradiol and Testosterone Free and Total Panel is often ordered when a patient presents with symptoms suggestive of hormonal imbalances. In women, these symptoms may include irregular or absent menstrual periods, hot flashes, mood swings, or signs of polycystic ovary syndrome (PCOS). In men, symptoms such as low libido, erectile dysfunction, fatigue, or reduced muscle mass may prompt testing. Additionally, this panel may be ordered for individuals undergoing fertility evaluations, as both estradiol and testosterone play crucial roles in reproductive health. It is also used to monitor hormone replacement therapy (HRT) in patients receiving treatment for conditions like menopause or hypogonadism. Adolescents experiencing delayed or precocious puberty may also undergo this testing to assess their hormonal development.

What the Estradiol and Testosterone Free and Total Panel Checks For

The Estradiol and Testosterone Free and Total Panel provides a detailed assessment of key hormones that influence sexual development, reproductive function, and overall health. Each test within the panel serves a specific purpose and contributes to a comprehensive understanding of hormonal balance.

Estradiol is the most potent form of estrogen and is primarily produced in the ovaries in women, with smaller amounts produced in the testes in men and in the adrenal glands in both sexes. In women, estradiol regulates the menstrual cycle, supports pregnancy, and maintains bone density. In men, it helps regulate libido, erectile function, and sperm production. Abnormal levels of estradiol can lead to symptoms such as menstrual irregularities, infertility, or osteoporosis in women, and gynecomastia (enlarged breast tissue) or sexual dysfunction in men.

Testosterone Total measures the overall amount of testosterone in the blood, including both bound and free forms. Testosterone is the primary male sex hormone, produced mainly in the testes in men and in smaller amounts in the ovaries in women and the adrenal glands in both sexes. It is essential for the development of male secondary sexual characteristics, such as facial hair and a deep voice, as well as for maintaining muscle mass, bone density, and libido. In women, testosterone contributes to energy levels, sexual desire, and overall well-being. Abnormal levels of total testosterone can indicate conditions such as hypogonadism, PCOS, or androgen excess.

Testosterone Free measures the fraction of testosterone that is not bound to proteins in the blood and is biologically active. Free testosterone is responsible for the hormone’s effects on tissues and organs. While total testosterone provides an overall picture of testosterone levels, free testosterone offers a more accurate assessment of hormonal activity, particularly in cases where protein binding may be altered, such as in obesity or liver disease. Low levels of free testosterone can lead to symptoms like fatigue, reduced muscle mass, and low libido, while high levels may cause acne, excessive hair growth, or aggression.

How a Healthcare Professional Would Use the Results of the Estradiol and Testosterone Free and Total Panel

Healthcare professionals use the results of the Estradiol and Testosterone Free and Total Panel to diagnose and manage a variety of hormonal disorders. For example, in women with irregular menstrual cycles or infertility, abnormal estradiol levels may indicate ovarian dysfunction or menopause. In men with symptoms of low testosterone, such as fatigue or reduced libido, low levels of total or free testosterone may suggest hypogonadism. Conversely, elevated testosterone levels in women may point to conditions like PCOS or adrenal disorders.

The results also guide treatment decisions, such as initiating or adjusting hormone replacement therapy (HRT) for menopausal women or men with hypogonadism. For patients undergoing fertility treatments, monitoring estradiol and testosterone levels can help optimize therapy and improve outcomes. In adolescents with delayed or precocious puberty, the panel can help determine whether hormonal imbalances are contributing to developmental issues.

Additionally, the panel is useful for monitoring the effectiveness of treatments over time. For instance, a patient on testosterone replacement therapy may have their free and total testosterone levels checked regularly to ensure that their hormone levels are within the target range. Similarly, a woman on estrogen therapy may have her estradiol levels monitored to assess the adequacy of her treatment.

The Estradiol and Testosterone Free and Total Panel is a critical diagnostic tool for evaluating hormonal health in both men and women. By measuring estradiol, total testosterone, and free testosterone, this panel provides valuable insights into reproductive function, sexual development, and overall well-being. Healthcare professionals rely on the results to diagnose hormonal imbalances, guide treatment decisions, and monitor the effectiveness of therapies. Whether used to address symptoms of hormonal dysfunction, evaluate fertility, or manage hormone replacement therapy, this panel plays a vital role in maintaining and restoring hormonal balance, ultimately improving patients’ quality of life.

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