The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
Also known as: Free T3, FT3, T3 Free
Also known as: Free T4, FT4, T4 Free
Also known as: Thyroid Stimulating Hormone, Thyroid Stimulating Hormone (TSH), Thyrotropin
The Compare - Thyroid Antibody Test (LGC) panel contains 4 tests with 6 biomarkers.
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The Thyroid Antibody lab test is a diagnostic assessment that measures various markers related to thyroid function and the presence of specific antibodies in the bloodstream. This panel includes markers such as Thyroid Stimulating Hormone (TSH), Free T3, Free T4, Thyroid Peroxidase Antibodies (TPO antibodies), and Thyroglobulin Antibodies (Tg antibodies). These tests collectively provide valuable insights into thyroid health and autoimmune thyroid disorders.
Collection Method: Blood Draw
Specimen Type: Serum
Test Preparation: Specifc to TSH: Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks.
According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra assay."
Timing of the Test: The Thyroid Antibody lab test is typically ordered when there are clinical indications or specific symptoms related to thyroid function or autoimmune thyroid diseases. It can be performed at any time, and fasting is generally not required.
Reasons for Ordering the Test:
Assessment of Thyroid Function: The Thyroid Antibody lab test is often ordered to assess thyroid function in individuals with symptoms such as fatigue, weight changes, temperature sensitivity, or changes in heart rate.
Diagnosis of Autoimmune Thyroid Disorders: The presence of thyroid antibodies, particularly Thyroid Peroxidase Antibodies (TPO antibodies) and Thyroglobulin Antibodies (Tg antibodies), is associated with autoimmune thyroid diseases such as Hashimoto's thyroiditis and Graves' disease. These antibodies may be measured to confirm the diagnosis of these conditions.
Monitoring Autoimmune Thyroid Conditions: For individuals with known autoimmune thyroid disorders, regular testing of thyroid antibodies helps monitor disease activity and treatment effectiveness.
Evaluation of Thyroid Nodules or Goiter: In cases of thyroid nodules or goiter, the Thyroid Antibody lab test may be ordered to assess thyroid function and the presence of autoimmune thyroid diseases, which can influence management decisions.
The Thyroid Antibody lab test assesses several markers:
Thyroid Stimulating Hormone (TSH): TSH is produced by the pituitary gland and regulates the thyroid's production of thyroid hormones, T3 and T4. Abnormal TSH levels can indicate thyroid dysfunction.
Free T3: Free T3 represents the biologically active form of triiodothyronine, one of the thyroid hormones responsible for regulating metabolism.
Free T4: Free T4 represents the biologically active form of thyroxine, another thyroid hormone that plays a crucial role in metabolism and energy production.
Thyroid Peroxidase Antibodies (TPO antibodies): TPO antibodies are markers of autoimmune thyroid diseases, particularly Hashimoto's thyroiditis. Elevated levels of TPO antibodies indicate an autoimmune attack on the thyroid gland.
Thyroglobulin Antibodies (Tg antibodies): Thyroglobulin is a protein produced by the thyroid gland. Elevated Tg antibody levels may suggest autoimmune thyroid disorders, though they are also used in monitoring thyroid cancer.
Healthcare providers use the results of the Thyroid Antibody lab test to:
Assess Thyroid Function: TSH, Free T3, and Free T4 levels help assess thyroid function. Abnormal levels can indicate hyperthyroidism or hypothyroidism.
Diagnose Autoimmune Thyroid Disorders: Elevated levels of Thyroid Peroxidase Antibodies (TPO antibodies) and Thyroglobulin Antibodies (Tg antibodies) confirm the diagnosis of autoimmune thyroid diseases, including Hashimoto's thyroiditis and Graves' disease.
Monitor Autoimmune Thyroid Conditions: For individuals with autoimmune thyroid disorders, regular testing of thyroid antibodies helps healthcare providers monitor disease activity, assess the effectiveness of treatment, and make necessary adjustments to medications or interventions.
Guide Treatment Decisions: The results of thyroid function and antibody tests guide treatment decisions for thyroid disorders. Treatment may involve hormone replacement therapy, antithyroid medications, or other interventions to manage thyroid function and reduce autoimmune activity.
In summary, the Thyroid Antibody lab test combines assessments of thyroid function and the presence of specific antibodies related to autoimmune thyroid diseases. It aids in diagnosing thyroid disorders, monitoring autoimmune thyroid conditions, guiding treatment decisions, and ensuring optimal thyroid health in individuals with thyroid-related concerns.
We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.