Cardio IQ® Myeloperoxidase (MPO)
The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
MYELOPEROXIDASE
The Cardio IQ® Myeloperoxidase (MPO) test contains 1 test with 1 biomarker.
Brief Description: The Cardio IQ® Myeloperoxidase (MPO) test is a diagnostic assessment designed to measure the levels of myeloperoxidase in the blood. Myeloperoxidase is an enzyme found primarily in white blood cells (neutrophils and monocytes) and is released when these cells become activated.
Collection Method: Blood Draw
Specimen Type: Plasma
Test Preparation: No preparation required
When and Why a Cardio IQ® Myeloperoxidase Test May Be Ordered
A physician may order a Cardio IQ® Myeloperoxidase test in the following scenarios:
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Cardiac Risk Assessment: As part of a comprehensive cardiac risk evaluation, especially in individuals who have traditional risk factors but no evident heart disease.
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History of Heart Disease: For patients with a known history of heart disease to gauge the risk of future cardiac events.
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Unexplained Chest Pain: To help in the differential diagnosis of chest pain that might be of cardiac origin.
What the Cardio IQ® Myeloperoxidase Test Checks For
The Cardio IQ® Myeloperoxidase test specifically evaluates:
- Myeloperoxidase Levels: Elevated levels of MPO in the blood can indicate the presence of inflammation in the blood vessels, which might signify a heightened risk for coronary artery disease (CAD) or acute coronary syndromes.
Other Lab Tests Ordered Alongside the Cardio IQ® Myeloperoxidase Test
When a Cardio IQ MPO test is ordered, it's often part of a broader evaluation of cardiovascular risk and inflammation. Here are some tests commonly ordered alongside it:
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High-Sensitivity C-Reactive Protein (hs-CRP):
- Purpose: To detect low levels of inflammation in the body.
- Why Is It Ordered: hs-CRP is a marker of systemic inflammation and is associated with an increased risk of cardiovascular diseases. Elevated hs-CRP can complement findings of high MPO levels.
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- Purpose: To measure levels of total cholesterol, LDL (low-density lipoprotein) cholesterol, HDL (high-density lipoprotein) cholesterol, and triglycerides.
- Why Is It Ordered: To assess lipid metabolism and the risk of atherosclerosis, which can be influenced by inflammation.
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- Purpose: To measure the level of Lp(a), a lipoprotein associated with an increased risk of cardiovascular diseases.
- Why Is It Ordered: To evaluate additional risk factors for cardiovascular disease, especially in individuals with a family history of heart disease.
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- Purpose: To measure the level of fibrinogen, a blood clotting protein.
- Why Is It Ordered: Elevated fibrinogen can indicate an increased risk of clotting and cardiovascular disease and can be associated with inflammation.
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- Purpose: To assess average blood glucose levels over the past 2-3 months.
- Why Is It Ordered: To evaluate blood sugar control, as diabetes or impaired glucose metabolism can increase the risk of cardiovascular disease.
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- Purpose: To measure the level of homocysteine, an amino acid linked to heart disease and stroke.
- Why Is It Ordered: Elevated homocysteine levels can increase the risk of cardiovascular diseases and may be associated with inflammation.
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- Purpose: To assess kidney function.
- Why Is It Ordered: Kidney disease can increase the risk of cardiovascular disease and may influence inflammation markers.
These tests, when ordered alongside a Cardio IQ Myeloperoxidase test, provide a comprehensive evaluation of cardiovascular risk, focusing on both traditional risk factors and markers of inflammation. They are crucial for identifying individuals at increased risk for cardiovascular events and guiding preventive and therapeutic strategies. The specific combination of tests will depend on the individual’s overall risk profile, medical history, and lifestyle factors.
Conditions or Diseases that Require a Cardio IQ® Myeloperoxidase Test
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Coronary Artery Disease (CAD): As MPO has been associated with the presence of vulnerable plaques that can lead to acute coronary events.
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Acute Coronary Syndromes: Such as heart attacks or unstable angina.
Usage of Cardio IQ® Myeloperoxidase Test Results by Health Care Providers
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Risk Stratification: Elevated MPO levels can indicate a higher risk for cardiac events. This can inform the physician on the urgency and aggressiveness of interventions.
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Treatment Planning: Based on MPO levels, physicians can decide on treatments ranging from lifestyle modifications, initiation or adjustment of medications, or more aggressive interventions like cardiac catheterization.
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Monitoring: Regular monitoring of MPO levels can provide insight into the effectiveness of treatments or interventions.
In summary, the Cardio IQ® Myeloperoxidase test is a valuable tool in assessing an individual's risk for cardiac events, especially in those with known heart disease or those who exhibit symptoms of cardiac conditions. The results can guide healthcare providers in making more informed clinical decisions to optimize patient outcomes.
Most Common Questions About the Cardio IQ® Myeloperoxidase test:
Purpose and Indications of the Cardio IQ® Myeloperoxidase Test
What is the primary purpose of the Cardio IQ® Myeloperoxidase test?
The Cardio IQ® Myeloperoxidase test is designed to measure the levels of myeloperoxidase (MPO) in the blood. Elevated levels of MPO are associated with inflammation of the blood vessels and can indicate an increased risk of coronary artery disease or other cardiovascular conditions.
Why would someone get the Cardio IQ® Myeloperoxidase test instead of or in addition to other cardiovascular risk tests?
The Cardio IQ® Myeloperoxidase test provides specific information about vascular inflammation, which is a potential precursor to plaque rupture and subsequent heart attack. While other cardiovascular risk tests evaluate different aspects of heart health, the Cardio IQ® Myeloperoxidase test offers a unique perspective on inflammation and its role in cardiovascular disease.
Interpreting the Results
What does a high result on the Cardio IQ® Myeloperoxidase test indicate?
A high result indicates elevated levels of MPO in the bloodstream, suggesting vascular inflammation. This can be indicative of an increased risk for coronary artery disease, heart attack, or other cardiovascular events, especially in individuals who might not display other traditional risk factors.
If the Cardio IQ® Myeloperoxidase test shows normal levels, does that mean there's no risk of cardiovascular disease?
While normal MPO levels suggest a reduced risk related to vascular inflammation, it does not eliminate the risk of cardiovascular disease entirely. Other factors, such as cholesterol levels, blood pressure, and lifestyle factors, also play crucial roles in overall cardiovascular health.
Implications and Management
What lifestyle or medical interventions might be recommended if someone has elevated levels on the Cardio IQ® Myeloperoxidase test?
Individuals with elevated MPO levels might be advised to adopt lifestyle changes like a heart-healthy diet, regular exercise, stress management, and avoiding smoking. Additionally, medication to address inflammation, lower cholesterol, or treat other associated conditions might be prescribed.
How does the Cardio IQ® Myeloperoxidase test fit into a comprehensive cardiovascular risk assessment?
The Cardio IQ® Myeloperoxidase test is one of many tools that healthcare providers use to assess cardiovascular risk. By evaluating vascular inflammation, it provides unique insights that complement other tests like lipid panels, C-reactive protein tests, and blood pressure measurements.
Test Mechanisms and Specifics
How often should someone get the Cardio IQ® Myeloperoxidase test?
The frequency of testing will vary based on individual risk factors, initial test results, and the recommendations of the healthcare provider. For someone with elevated levels or significant risk factors, more frequent monitoring might be advised.
How does the Cardio IQ® Myeloperoxidase test differ from other inflammatory markers like C-reactive protein?
While both the Cardio IQ® Myeloperoxidase test and tests for C-reactive protein (CRP) measure inflammation, they target different markers. MPO is specific to vascular inflammation, while CRP is a general marker of inflammation in the body. Both can be used in conjunction to provide a more comprehensive view of cardiovascular risk related to inflammation.
Additional Information
How can patients ensure the accuracy of the Cardio IQ® Myeloperoxidase test?
Ensuring the sample is properly collected, stored, and transported is essential. Following the lab's guidelines and any pre-test instructions can also help improve accuracy. Moreover, discussing any potential medications or conditions that might influence the test results with a healthcare provider is recommended.
In the context of heart health, how should the results of the Cardio IQ® Myeloperoxidase test be integrated with other test results and clinical signs?
The results of the Cardio IQ® Myeloperoxidase test should be considered as part of a broader cardiovascular risk assessment. Combining this test's insights with other clinical signs, patient history, and results from additional tests will give a more comprehensive view of an individual's heart health and risk factors.
We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.
Performing Laboratory
Cleveland HeartLab, Inc
6701 Carnegie Avenue, Suite 500
Cleveland, OH 44103-4623
- $122.95