Bone Plus Comprehensive Panel: Enhanced Insights for Optimal Bone Health

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Alk Phos Bone Specific, Alkaline Phosphatase Bone Specific, Bone Specific Alk Phos, BSAP, OSTASE

ALKALINE PHOSPHATASE,

Also known as: C-Reactive Protein, CReactive Protein CRP, CRP

C-REACTIVE PROTEIN

C-reactive protein is produced by the liver. The level of CRP rises when there is inflammation throughout the body.

Also known as: Cortisol Total, Hydrocortisone, Total Cortisol

Cortisol, Total

Also known as: Estrogen Total Serum

Estrogen, Total, Serum

Estrogen is a group of steroids that regulate the menstrual cycle and function as the main female sex hormones. Estrogens are responsible for the development of female sex organs and secondary sex characteristics and are tied to the menstrual cycle and pregnancy. They are considered the main sex hormones in women and are present in small quantities in men.

Ferritin

Ferritin is a protein found inside cells that stores iron so your body can use it later. A ferritin test indirectly measures the amount of iron in your blood. The amount of ferritin in your blood (serum ferritin level) is directly related to the amount of iron stored in your body.

Also known as: Folate Serum, Folic Acid

Folate, Serum

Folate is part of the B complex of vitamins and is measures the levels of folate in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Folate is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis.. A deficiency inr folate can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow.

Also known as: Homocysteine, Homocysteine Cardiovascular

HOMOCYSTEINE,

Also known as: IGF-1, IGFI LCMS, Insulin-Like Growth Factor, Insulin-like Growth Factor - 1, Somatomedin C, Somatomedin-C

Igf I, LC/MS

The insulin-like growth factor-1 (IGF-1) test is an indirect measure of the average amount of growth hormone (GH) being produced by the body. IGF-1 and GH are polypeptide hormones, small proteins that are vital for normal bone and tissue growth and development. GH is produced by the pituitary gland, a grape-sized gland located at the base of the brain behind the bridge of your nose. GH is secreted into the bloodstream in pulses throughout the day and night with peaks that occur mostly during the night. IGF-1 is produced by the liver and skeletal muscle as well as many other tissues in response to GH stimulation. IGF-1 mediates many of the actions of GH, stimulating the growth of bones and other tissues and promoting the production of lean muscle mass. IGF-1 mirrors GH excesses and deficiencies, but its level is stable throughout the day, making it a useful indicator of average GH levels.

Z Score (Female)

z Score. A z-score (aka, a standard score) indicates how many standard deviations an element is from the mean. A z-score can be calculated from the following formula. z = (X - µ) / s where z is the z-score, X is the value of the element, µ is the population mean, and s is the standard deviation.

Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC

% Saturation

Iron Binding Capacity

Total iron binding capacity (TIBC) is a blood test to see if you may have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.

Iron, Total

Iron is a mineral that our bodies need for many functions. For example, iron is part of hemoglobin, a protein which carries oxygen from our lungs throughout our bodies. It helps our muscles store and use oxygen. Iron is also part of many other proteins and enzymes. Your body needs the right amount of iron. If you have too little iron, you may develop iron deficiency anemia. Causes of low iron levels include blood loss, poor diet, or an inability to absorb enough iron from foods. People at higher risk of having too little iron are young children and women who are pregnant or have periods.

Magnesium

Also known as: Osteocalcin NMID

OSTEOCALCIN, N MID

Also known as: Inorganic Phosphate, P, Phosphate as Phosphorus, Phosphorus, PO4

Phosphate (As Phosphorus)

This test is performed to see how much phosphorus in your blood. Kidney, liver, and certain bone diseases can cause abnormal phosphorus levels.

Also known as: Protein Electrophoresis Serum, SPEP

Abnormal Protein Band 1

Abnormal Protein Band 2

Abnormal Protein Band 3

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Alpha-1-Globulins

Alpha-2-Globulins

BETA 1 GLOBULIN

BETA 2 GLOBULIN

Gamma Globulins

Interpretation

Protein, Total

The total protein is the total amount of two classes of proteins, albumin and globulin that are found in the fluid portion of your blood. Proteins are important parts of all cells and tissues. Your albumin helps prevent fluid from leaking out of blood vessels and your globulins are an important part of your immune system.

Also known as: "Biointact" PTH and Calcium, Intact PTH and Calcium, Parathyroid Hormone and Calcium, PTH and Calcium, PTH Intact and Calcium

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.

PARATHYROID HORMONE,

PTH stands for parathyroid hormone. It is a protein hormone released by the parathyroid gland. Parathyroid hormone controls calcium, phosphorus, and vitamin D levels in the blood and bone. Release of PTH is controlled by the level of calcium in the blood. Low blood calcium levels cause increased PTH to be released, while high blood calcium levels block PTH release.

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Bun/Creatinine Ratio

A ratio between a person’s BUN and blood creatinine to help determine what is causing these concentrations to be higher than normal. The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration. It may also be seen with increased protein, from gastrointestinal bleeding, or increased protein in the diet. The ratio may be decreased with liver disease (due to decrease in the formation of urea) and malnutrition.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.

Carbon Dioxide

CO2 is carbon dioxide. Measures the amount of carbon dioxide in the liquid part of your blood, called the serum. In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.

Chloride

Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance. This is a measure of the amount of chloride in the fluid portion (serum) of the blood.

Creatinine

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys work.

Egfr African American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

Egfr Non-Afr. American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Phosphate (As Phosphorus)

This test is performed to see how much phosphorus in your blood. Kidney, liver, and certain bone diseases can cause abnormal phosphorus levels.

Potassium

Potassium is a mineral that the body needs to work normally. It helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Sodium

Sodium is a substance that the body needs to work properly it is vital to normal body processes, including nerve and muscle function

Urea Nitrogen (Bun)

BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down. BUN measures the amount of urea nitrogen in the blood.

Selenium

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Also known as: Testosterone Free Dialysis and Total LCMSMS

Free Testosterone

In many cases, measurement of total testosterone provides the doctor with adequate information. However, in certain cases, for example when the level of SHBG is abnormal, a test for free or bioavailable testosterone may be performed as it may more accurately reflect the presence of a medical condition.

TESTOSTERONE, TOTAL,

A testosterone test measures the amount of the male hormone, testosterone, in the blood. Both men and women produce this hormone. In males, the testicles produce most of the testosterone in the body. Levels are most often checked to evaluate signs of low testosterone: In boys -- early or late puberty and in men -- impotence, low level of sexual interest, infertility, thinning of the bones In females, the ovaries produce most of the testosterone and levels are most often checked to evaluate signs of higher testosterone levels, such as: decreased breast size, excess hair growth, increased size of the clitoris. irregular or absent menstrual periods and male-pattern baldness or hair thinning.

Also known as: Thyroid Stimulating Hormone, Thyroid Stimulating Hormone (TSH), Thyrotropin

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

TSH

Also known as: ,25-Hydroxyvitamin D2, 25-Hydroxycholecalciferol (25OHD3), 25-OH-D2,D3 Vitamin, D2 Vitamin,25-Hydroxyvitamin D3,25-OH-D3, QuestAssureD 25Hydroxyvitamin D D2 D3 LCMSMS, Vitamin D, Vitamin D, 25-Hydroxy, Vitamin D2, 25-hydroxy,25-Hydroxyergocalciferol (25OHD2),Vitamin D3, 25-hydroxy

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Also known as: ZN, Plasma

Zinc

*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through Quest Diagnostics. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 Quest Diagnostics laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Bone Plus Comprehensive Panel: Enhanced Insights for Optimal Bone Health panel contains 22 tests with 51 biomarkers.

The Bone Plus Comprehensive Panel: Enhanced Insights for Optimal Bone Health is an advanced suite of tests. It includes the foundational assessments of the Bone Essentials Panel and expands them with additional critical evaluations. This provides a thorough understanding of factors influencing bone health.

This comprehensive approach not only addresses the basic components of bone strength but also explores broader physiological factors. These can impact bone density, growth, and healing.

Below are expanded descriptions for the additional tests included in this panel:

  • Estrogen/Testosterone Levels: Estrogen and testosterone are key hormones that support bone density and health. In both women and men, optimal levels of these sex hormones are critical for maintaining bone strength; low levels can lead to increased bone loss and a higher risk of osteoporosis. This test assesses hormone levels to identify potential imbalances that may necessitate intervention.
  • Thyroid Function Tests (TSH, FT3, FT4): Thyroid hormones play a significant role in regulating metabolism and affect bone density. Imbalances, such as hyperthyroidism or hypothyroidism, can disrupt normal bone replacement cycles, leading to weaker bones. This series of tests evaluates thyroid health and its impact on bone integrity.
  • Cortisol Test: Chronic stress, reflected in elevated cortisol levels, can have a detrimental effect on bone density by influencing the rate of bone turnover. This test measures cortisol levels to determine if stress might be impacting bone health, guiding strategies for management and mitigation.
  • C-Reactive Protein (CRP) Test: CRP levels can indicate the presence of inflammation in the body, which has been linked to increased bone loss and a higher risk of fractures. By identifying elevated CRP levels, this test helps assess the risk of inflammation-related bone density issues.
  • Serum Protein Electrophoresis: This test is utilized in the diagnosis of multiple myeloma, a type of cancer that originates in the plasma cells of bone marrow and can lead to weakened bones and fractures. Early detection is crucial for managing the disease and mitigating its impact on bone health.
  • Renal Function Panel: Kidney health is vital for maintaining the balance of calcium and phosphorus, two minerals essential for bone health. This panel assesses kidney function to ensure it is not adversely affecting bone density through imbalanced mineral levels.
  • Iron and Ferritin Tests: Iron is essential for numerous bodily functions, including oxygen transport and energy production. Abnormal levels, either too low or too high, can indirectly influence bone health. These tests measure iron levels and storage, offering insights into potential areas of concern.
  • Homocysteine Test: Elevated homocysteine levels have been linked to an increased risk of fractures, particularly in older adults. This test evaluates the risk posed by high homocysteine levels to bone integrity and guides interventions to mitigate this risk.
  • Selenium Test: Selenium's antioxidant properties support bone health, and deficiencies in this mineral have been associated with increased risk of osteoporosis. This test checks selenium levels to ensure they are adequate for supporting bone structure and health.
  • Zinc Test: Zinc is crucial for bone growth, healing, and development. Insufficient zinc levels can impair these processes, affecting overall bone health. This test assesses zinc status to guide dietary or supplementation recommendations.
  • Folate Test: Folate, a B vitamin, is important for cell function and health, including the cells involved in bone formation and maintenance. This test measures folate levels to ensure they are sufficient for optimal bone health.
  • Insulin Growth Factor-1 (IGF-1) Test: IGF-1 plays a critical role in bone growth and density. Abnormal levels, either too high or too low, can have adverse effects on bone health. This test measures IGF-1 levels to identify imbalances that may affect bone density and growth.

PLUS THE TESTS IN THE Bone Essentials Panel;

  • Calcium Test: Checking your blood for calcium is super important. Calcium does a lot more than just keep your bones strong. It helps your nerves send messages, your muscles to move, and your heart to beat the right way. If you don't have enough, or if you have too much, it could be a sign of other health problems that need to be looked at.
  • Vitamin D Test: Vitamin D helps your body grab calcium from the food you eat, which is a big deal for keeping your bones tough and strong. This test checks how much Vitamin D is in your body to make sure you're getting enough to take care of your bones. Not having enough Vitamin D can make your bones hurt and get weak, which might mean you need to change what you eat or take supplements.
  • Parathyroid Hormone (PTH) Test: The PTH test checks out a special hormone in your blood that keeps your calcium levels in check. If this hormone level is too high, it could mean your body is pulling calcium out of your bones, making them weaker. This test is key for spotting issues with your parathyroid glands and other calcium-related problems.
  • Bone Alkaline Phosphatase (Bone ALP) Test: This test measures an enzyme that has to do with growing new bone and breaking down old bone. If you have a lot of this enzyme, it might mean your bones are being broken down faster than they can be rebuilt, which could happen with certain bone diseases or after breaking a bone. It's a good way to keep an eye on bone health and how well treatment is working.
  • Osteocalcin Test: Osteocalcin is a protein that's all about building bones, made by cells called osteoblasts. This test sees how much of it you have in your blood, which can tell us about how fast your bones are being made or broken down. High levels are a good sign of bone building, while low levels might mean it's slowing down.
  • Phosphorus Test: Phosphorus teams up with calcium to make your bones strong. This test checks your blood for phosphorus to make sure you have the right amount for healthy bones. Too much or too little can cause bone problems or pain.
  • Magnesium Test: Magnesium is another mineral that's crucial for bone health. It helps keep your bone structure solid and plays a part in how your body uses calcium and vitamin D. This test makes sure you have enough magnesium for your bones to stay healthy. Not enough magnesium can lead to weaker bones and other bone health issues.

The Bone Plus Comprehensive Panel is like a super-detailed map for your bone health. It looks at a lot of different things that can affect how strong your bones are, from the minerals in your body to how well certain organs are working.

With all this information, you can make the best plan to take care of your bones. Whether that means changing your diet, getting more of certain nutrients, or keeping an eye on other health conditions, this panel guides you towards what's best for your bone health.

It's a smart way to make sure your bones stay strong and healthy as you grow. Let's make bone health a priority, so you can keep doing all the things you love without worry.

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