Ulta Lab Tests

ANCA Screen with MPO and PR3 with Reflex to ANCA Titer

The ANCA Screen with MPO and PR3 with Reflex to ANCA Titer detects antineutrophil cytoplasmic antibodies linked to autoimmune vasculitis. By targeting myeloperoxidase (MPO) and proteinase 3 (PR3), this test helps evaluate conditions such as granulomatosis with polyangiitis or microscopic polyangiitis. It supports diagnosis, disease activity monitoring, and assessment of autoimmune inflammation.

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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: ANCA Screen with MPO and PR3 with Reflex to ANCA Titer

Anca Screen

Atypical P-Anca Titer

C-Anca Titer

Myeloperoxidase Antibody

Antineutrophil cytoplasmic antibodies (ANCA) are a group of autoantibodies produced when a person's immune system mistakenly targets and attacks its own neutrophil proteins. Two of the most commonly targeted proteins are myeloperoxidase (MPO) and proteinase 3 (PR3). This results in the production of antibodies to MPO and/or PR3. The ANCA blood test detects the presence or absence of these autoantibodies. Antineutrophil cytoplasmic antibodies may be present in a variety of autoimmune disorders that cause inflammation and damage to blood vessels throughout the body (systemic vasculitis). Vasculitis can cause tissue and organ damage due to the narrowing and obstruction of blood vessels and the subsequent loss of blood supply. It can also produce areas of weakness in blood vessel walls, known as aneurysms, which have the potential to rupture.

P-Anca Titer

Proteinase-3 Antibody

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The ANCA Screen with MPO and PR3 with Reflex to ANCA Titer test contains 1 test with 6 biomarkers .

Testing for anti-neutrophil cytoplasmic antibodies (P-ANCA and/or C-ANCA) has been found to be useful in establishing the diagnosis of suspected vascular diseases, inflammatory bowel disease, as well as other autoimmune diseases.

Additional test processing fees will be charged if initial results dictate Reflex (further) testing.

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