Interleukin-2 Receptor, EIA

The Interleukin-2 Receptor, EIA test contains 1 test with 2 biomarkers.

Clinical Use
Assess T-cell activation following transplantation
Assess prognosis in patients with lymphoma
Monitor therapeutic response in patients with hairy cell leukemia


Clinical Background
Elevated levels of soluble IL-2 receptor are detected in AIDS, autoimmune diseases, sarcoidosis, and a variety of leukemias and lymphomas. In HIV-positive individuals, the IL-2 receptor level is elevated during the asymptomatic phase, as well as during persistent generalized lymphadenopathy and symptomatic phases. IL-2 receptor detection may be useful in monitoring HIV and in assessing T-cell activation following transplantation. Elevated IL-2 receptor levels may also have clinical and prognostic significance in patients with malignant lymphoma, non-Hodgkin's lymphoma, B-cell, and undifferentiated lymphomas.


Studies have suggested that IL-2 receptor levels in a broad spectrum of conditions associated with T- or B-cell immune activation offer a rapid and reliable measure of disease activity, response to therapy, and, in some cases, prognosis. Measurement of the soluble IL-2 receptor level is also helpful in assessing therapeutic response in patients with hairy cell leukemia.


Method
Enzyme immunoassay (EIA)

Clinical Significance 

Following stimulation by antigen, IL-2R is expressed on all T cells. IL-2R is released by activated cells into the surrounding extracellular fluid. IL2-R is involved in infectious, inflammatory and autoimmune diseases, cancer, and transplantation. IL-2R Antibodies are used therapeutically.

Alternative Name(s) 

IL-2 Receptor,  CYTOKINE

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Interleukin 2 Receptor Eia

INTERLEUKIN 2 RECEPTOR

Interleukin 2 Receptor,

*Process times are an estimate and are not guaranteed. The lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.