Endocrine Tests

Your endocrine system is a network of glands that release hormones to control energy, growth, mood, reproduction, and fluid balance. When hormones are too high or too low, you may notice fatigue, weight changes, irregular periods, hair/skin changes, or blood-pressure and glucose shifts.

Endocrine testing uses targeted blood and urine tests to evaluate these glands—thyroid, adrenals, pituitary, ovaries/testes, and parathyroids—and related systems. A proactive plan often begins with TSH and thyroid hormonesglucose/A1c, and electrolytes, then adds adrenal, pituitary, and reproductive mark... See more

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The Aldosterone Test measures levels of aldosterone, a hormone produced by the adrenal glands that helps regulate blood pressure, sodium, and potassium balance. Abnormal levels may indicate primary aldosteronism, adrenal tumors, kidney disease, or secondary hypertension. Doctors use this blood test to investigate high blood pressure, electrolyte imbalances, or suspected adrenal disorders, helping guide diagnosis, treatment, and long-term patient management.

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Also Known As: Aldosterone Plasma Test

The Plasma Renin Activity Test evaluates how much renin the kidneys release, providing insight into blood pressure control and fluid regulation. Abnormal activity may suggest hypertension, adrenal gland dysfunction, or kidney disease. This test supports assessment of aldosterone-renin ratio, secondary hypertension, and systemic conditions that impact cardiovascular and renal health.

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The Growth Hormone Test measures GH levels in blood to evaluate pituitary gland function, growth disorders, and metabolic health. Abnormal levels may indicate acromegaly, gigantism, or growth hormone deficiency. Doctors use this test to assess children with short stature, adults with suspected hormone imbalance, or patients with pituitary tumors. Results provide critical insight into endocrine function, metabolism, and overall growth regulation.

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Also Known As: GH Test, HGH Test, Human Growth Hormone Test, Somatotropin Test

The Estrogen Total Test measures all forms of estrogen in blood, including estradiol, estrone, and estriol, to assess reproductive and hormonal health. Abnormal levels may indicate menstrual irregularities, menopause status, infertility, or hormone-related disorders. Doctors order this test to evaluate fertility, monitor hormone therapy, and investigate symptoms such as hot flashes, irregular cycles, or abnormal bleeding. It provides key insight into endocrine and reproductive function.

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Also Known As: Total Estrogen Test, Estrogen Serum Test

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The FSH and LH Test measures follicle-stimulating hormone (FSH) and luteinizing hormone (LH) to evaluate reproductive and endocrine health in both men and women. In women, it helps assess menstrual irregularities, infertility, menopause, or polycystic ovary syndrome (PCOS). In men, it aids in diagnosing low testosterone, infertility, or testicular dysfunction. Doctors also use this test to investigate puberty disorders, hormone imbalance, and pituitary function.

Also Known As: Follitropin Test, Lutropin Test, Interstitial Cell Stimulating Hormone Test, ICSH Test

The Sex Hormone Binding Globulin (SHBG) Test measures SHBG, a protein that binds testosterone and estrogen, to assess how much active hormone is available in the body. Abnormal levels may indicate PCOS, infertility, low testosterone, liver disease, or thyroid disorders. Doctors order this test to investigate symptoms like low libido, irregular periods, acne, or hair loss and to evaluate hormone balance, endocrine function, and metabolic health in men and women.

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Also Known As: SHBG Test, TeBG Test, Testosterone-Estrogen Binding Globulin Test

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The LH Test measures luteinizing hormone levels in blood to assess fertility, reproductive health, and endocrine function. Abnormal LH may indicate infertility, menstrual irregularities, menopause, or pituitary disorders in women, and low testosterone or testicular dysfunction in men. Doctors use this test to evaluate ovulation, investigate infertility, monitor puberty disorders, or guide hormone therapy. It provides key insight into reproductive and hormonal balance.

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Also Known As: Luteinizing Hormone Test, Lutropin Test, Interstitial Cell Stimulating Hormone Test, ICSH Test

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The Progesterone Test measures progesterone levels in blood to evaluate ovulation, fertility, and menstrual health. It helps confirm whether ovulation has occurred, assess causes of infertility, and monitor hormone therapy or high-risk pregnancies. Doctors also use it to investigate abnormal bleeding, detect ovarian or adrenal disorders, and evaluate miscarriage risk. This test provides key insight into reproductive, hormonal, and overall endocrine health.

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Also Known As: PGSN Test

The Progesterone Ultrasensitive Test measures very low progesterone levels in blood with high accuracy to evaluate reproductive and endocrine health. Doctors use it to assess menstrual cycle function, confirm ovulation, investigate infertility, and monitor hormone therapy. It is also useful in pregnancy evaluation and detecting hormonal disorders. Results provide precise insight into progesterone balance, fertility, and overall reproductive health.

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Also Known As: Ultrasensitive PGSN, Progesterone LCMS Test

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The IGF-1 Test measures insulin-like growth factor 1, a hormone regulated by growth hormone (GH), to assess growth and endocrine function. Abnormal levels may indicate growth disorders, acromegaly, gigantism, or GH deficiency. Doctors order this test to evaluate delayed growth, short stature, excessive growth, or pituitary disease and to monitor GH therapy. Results provide valuable insight into hormone balance, metabolism, and overall endocrine health.

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Also Known As: Insulin-like Growth Factor 1 Test, Somatomedin-C Test, IGF-I Test

The IGF Binding Protein 1 (IGFBP-1) Test measures IGFBP-1, a protein that regulates insulin-like growth factor (IGF) activity and reflects insulin sensitivity. Abnormal levels may indicate insulin resistance, type 2 diabetes risk, or metabolic syndrome. Doctors use this test to evaluate glucose regulation, investigate metabolic disorders, and support early detection of endocrine imbalances that affect growth, energy balance, and long-term health.

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Also Known As: IGFBP-1 Test

The IGF Binding Protein 3 (IGFBP-3) Test measures IGFBP-3, the primary carrier of insulin-like growth factor 1 (IGF-1), to evaluate growth hormone activity. Abnormal levels may indicate growth disorders, pituitary dysfunction, or nutritional problems. Doctors use this test with IGF-1 to assess short stature, delayed or rapid growth, and monitor therapy for growth hormone deficiency or excess, supporting accurate diagnosis and treatment.

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Also Known As: IGFBP-3 Test

The PTH Intact with Calcium Test measures parathyroid hormone (PTH) levels alongside calcium in the blood to evaluate parathyroid gland function and calcium balance. Abnormal results may indicate hyperparathyroidism, hypoparathyroidism, kidney disease, or vitamin D disorders. Doctors order this test when patients experience bone pain, kidney stones, or abnormal calcium levels. Results help diagnose metabolic bone disease and guide treatment for calcium-related conditions.

Also Known As: Parathyroid Hormone Intact with Calcium Test, Intact PTH with Calcium Test

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The PTH Intact Test measures intact parathyroid hormone (PTH) levels in blood to evaluate parathyroid gland function and calcium balance. Abnormal PTH may indicate hyperparathyroidism, hypoparathyroidism, kidney disease, or vitamin D imbalance. Doctors use this test to investigate osteoporosis, kidney stones, or unexplained calcium abnormalities. Results provide vital insight into endocrine function, bone metabolism, and overall calcium regulation.

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Also Known As: Parathyroid Hormone Intact test, Intact PTH test, Parathormone Test

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The Amylase Test measures amylase enzyme levels in blood to evaluate pancreatic and digestive health. Elevated amylase may indicate pancreatitis, gallbladder disease, intestinal blockage, or salivary gland disorders, while low levels may suggest chronic pancreatitis or liver damage. Doctors order this test to investigate abdominal pain, nausea, or fever. Results provide vital insight into pancreatic function, digestive disorders, and overall metabolic health.

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Also Known As: Amy Test

The Beta-2-Glycoprotein I IgG IgA IgM Antibodies Test detects autoantibodies linked to antiphospholipid syndrome (APS), a disorder that increases risk of abnormal blood clotting. Measuring all three antibody classes provides a thorough evaluation of immune activity. Elevated results may be associated with recurrent miscarriages, venous or arterial thrombosis, and autoimmune conditions, supporting diagnosis and monitoring of clotting-related disorders.


The Beta-2-Glycoprotein I IgA Antibody Test detects IgA antibodies targeting beta-2 glycoprotein I, helping identify autoimmune conditions and clotting disorders. Positive results may indicate antiphospholipid syndrome, thrombotic risk, or pregnancy complications. This test provides insight into immune activity, vascular health, and systemic conditions linked to abnormal coagulation and inflammation.

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The Beta-2-Glycoprotein I IgG Antibody Test detects IgG antibodies targeting beta-2 glycoprotein I, helping assess autoimmune disorders and clotting risk. Positive results may indicate antiphospholipid syndrome, pregnancy complications, or thrombotic conditions. This test provides insight into vascular health, immune response, and systemic disorders related to antibody activity and coagulation balance.

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The Beta-2-Glycoprotein I IgM Antibody Test detects IgM antibodies targeting beta-2 glycoprotein I to help assess autoimmune activity and clotting disorders. Positive findings may suggest antiphospholipid syndrome, thrombotic risk, or recurrent miscarriage. This test provides insight into vascular health, immune regulation, and systemic disorders tied to antibody activity and coagulation balance.

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The Cardio IQ™ Triglycerides Test measures triglyceride levels in the blood, an important marker of lipid metabolism and cardiovascular health. Elevated triglycerides are linked to increased risk of heart disease, pancreatitis, and metabolic syndrome. Physicians use this test to assess risk factors, monitor therapy response, and guide lifestyle or treatment decisions, often as part of a broader lipid or heart health evaluation.

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The Catecholamines Fractionated 24-Hour Urine Test with Creatinine measures epinephrine, norepinephrine, and dopamine excretion, normalized to creatinine, to assess adrenal gland and sympathetic nervous system function. Elevated levels may indicate pheochromocytoma, paraganglioma, or other neuroendocrine tumors. This test supports evaluation of unexplained hypertension, palpitations, and symptoms linked to catecholamine excess.

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The Catecholamines Fractionated Random Urine Test analyzes urinary dopamine, norepinephrine, and epinephrine to assess adrenal medulla activity and sympathetic function. Elevated catecholamines may suggest adrenal tumors such as pheochromocytoma or paraganglioma, while abnormalities can reflect neuroblastoma or stress-related disorders. This test provides insight into hormone regulation and systemic health.

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The Electrolyte Panel Test measures sodium, potassium, chloride, and carbon dioxide in blood to evaluate fluid balance, kidney function, and acid-base status. Abnormal results may indicate dehydration, kidney disease, adrenal disorders, or respiratory issues. Doctors use this test to investigate symptoms such as weakness, confusion, or irregular heartbeat. Results provide essential insight into electrolyte balance, hydration, and overall metabolic and organ health.

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Also Known As: Lytes Panel, Anion Gap Panel, Electrolyte Test, Lytes Test, Anion Gap Test

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The Estradiol (E2) Test measures levels of estradiol, the primary form of estrogen, to evaluate reproductive and hormonal health. It helps assess menstrual irregularities, fertility issues, menopause status, and estrogen-producing disorders. In men, it aids in diagnosing hormonal imbalances. Doctors use the estradiol test to monitor hormone therapy, ovarian function, and conditions affecting puberty, bone health, and overall endocrine balance.

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Also Known As: E2 Test, Estrogen 2 Test

Have you been experiencing fluctuations in weight, mood swings, hair loss, or insomnia? If so, it may be a hormone imbalance. 

Your endocrine system is responsible for producing hormones in your body. If your hormones are unbalanced, they can throw your whole body off. 

Metabolism, sexual function, reproduction, sleep, weight, and mood are all regulated by hormones. Keeping your endocrine system running well is essential. 

If you're feeling like there is something disrupting your hormones, it is important that you look into endocrine tests to find out what is actually going on. 

Let's look into this deeper.

What Are Endocrine Disorders?

Your endocrine system is one of the most important parts of your body. In simple terms, an endocrine disorder is when your endocrine system is malfunctioning, and a gland in the body isn't doing its job correctly. 

Diabetes ... See more

 The endocrine system is a network that is made up of different glands throughout the human body. The endocrine system and the nervous system work together to regulate and control many of the internal functions of the body. The nervous system makes use of nerve impulses as its means for control; the endocrine system utilizes hormones, which are chemical messenger molecules. These hormones are created, stored, as well as secreted by an integrated network of different glands. When endocrine glands release different hormones into the blood, they will target specific organs, tissues, or cells. Every target will have dedicated receptors for that specific hormone, which can be explained as a key that fits into a lock.  

This network is made up of several parts. One of these is the hypothalamus, which is the endocrine gland situated in the brain. Another includes the pituitary gland, located in its ... See more