All Bone and Joint Tests

Aside from your medical history, bone and joint lab tests can help your doctor to diagnose if you have any bone or joint conditions. Here are some of the laboratory tests that you can undergo:

  • Blood Tests: Blood tests measure the various components of your blood. They are useful in detecting rheumatoid arthritis and other bone and joint disorders. Here are some of the blood tests that you can order from Ulta Lab Tests: 
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 The Bone Specific Alkaline Phosphatase (BSAP) test is a blood test that measures the level of bone-specific alkaline phosphatase, an enzyme primarily produced by cells known as osteoblasts that are involved in the formation of bone. It serves as a marker for bone formation and turnover.
: Serum

: Serum, Random, Blood

: Serum, Urine

The QuestAssureD™ Vitamin D 25-Hydroxy Total Test measures Vitamin D2, Vitamin D3, and total 25-hydroxy vitamin D to assess overall vitamin D status. Adequate vitamin D supports bone strength, calcium absorption, immune health, and muscle function. Low levels may cause osteoporosis, weakness, or increased disease risk, while high levels can indicate toxicity. Doctors use this test to diagnose deficiency, monitor supplementation, and evaluate metabolic and endocrine health.

: Serum
Also Known As: Ergocalciferol Test, Vitamin D2 Test, Cholecalciferol Test, Vitamin D3 Test, Calcidiol Test, 25-hydroxyvitamin D Test, Calcifidiol Test, 25-hydroxy-vitamin D Test, Vitamin D Total Test

The Vitamin D 1,25-Dihydroxy Test measures the active form of vitamin D in the blood, known as calcitriol. It helps evaluate calcium balance, bone health, and parathyroid function, and is often used to investigate kidney disease, certain metabolic disorders, or abnormal calcium levels.

: Serum
Also Known As: Calcitriol Test

The C-Reactive Protein (CRP) Test measures CRP levels in blood to detect inflammation in the body. Elevated CRP may indicate infections, autoimmune disorders, or chronic diseases such as arthritis, cardiovascular disease, or inflammatory bowel disease. Doctors use this test to assess acute illness, monitor treatment response, and evaluate risk for heart disease. The CRP test provides key insight into inflammation, immune health, and overall wellness.

: Serum
Also Known As: CRP Test, Inflammation Test

The Calcium Micronutrient Test measures calcium levels in the blood to assess nutritional status and detect imbalances. Calcium is essential for strong bones and teeth, muscle contraction, nerve signaling, and heart function. This test helps identify deficiencies, excess, or issues with absorption and metabolism, supporting diagnosis and management of bone health, hormonal balance, and overall wellness.

Patient must be 18 years of age or older.
: Serum
Also Known As: Ca Test, Serum Calcium Test, Calcium Blood Test

Most Popular

The Calcium Test measures calcium levels in the blood to help evaluate bone health, nerve and muscle function, and heart activity. Abnormal levels may indicate issues with the parathyroid glands, kidneys, bones, or nutritional balance.

: Serum
Also Known As: Ca Test, Serum Calcium Test, Calcium Blood Test

The Heavy Metals Micronutrients Blood Test Panel measures levels of arsenic, cadmium, cobalt, lead, and mercury to assess exposure and potential toxicity. These metals, found in the environment, food, or workplaces, can affect the nervous system, kidneys, bones, and overall health. This panel helps detect harmful accumulation, guide treatment, and monitor risks from environmental or occupational exposure.

Patient must be 18 years of age or older.

 The Calcium 24 Hour Urine with Creatinine Test is a diagnostic examination that analyzes both calcium and creatinine levels in a urine sample collected over a 24-hour period. Calcium is a vital mineral necessary for numerous bodily functions including muscle function, nerve transmission, and bone formation. On the other hand, creatinine is a waste product derived from the normal wear and tear of muscles. Evaluating both calcium and creatinine levels in a single test helps to determine the calcium-to-creatinine ratio, which can provide valuable insights into the functioning and health of the kidneys, as well as other related metabolic conditions.

The Comprehensive Metabolic Panel (CMP) Test measures 21 markers to assess metabolic health, liver and kidney function, and electrolyte balance. It includes glucose, calcium, sodium, potassium, chloride, CO2, albumin, globulin, A/G ratio, total protein, bilirubin, ALP, AST, ALT, BUN, creatinine, BUN/creatinine ratio, and eGFR. The CMP helps detect diabetes, liver or kidney disease, and supports routine screening and chronic condition monitoring.

: Serum
Also Known As: CMP Test, Chemistry Panel Test, Chem Test, Chem 21 Test, Chem 14 Test 

The Complete Blood Count with Differential and Platelets Test is a comprehensive blood test that checks red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. The differential analyzes types of white blood cells to detect infections, anemia, clotting abnormalities, immune conditions, and certain cancers. This essential test is often ordered for routine health exams, diagnosis, and monitoring treatment progress.

: Blood
Also Known As: CBC Test, CBC with Differential and Platelets Test, CBC w/Diff and Platelets Test, Full Blood Count Test, Complete Blood Count Test

The Rheumatoid Factor (RF) Test measures the level of rheumatoid factor antibodies in the blood. Elevated RF may indicate autoimmune conditions such as rheumatoid arthritis, Sjögren’s syndrome, or other inflammatory disorders, and helps support diagnosis and monitoring.

: Serum
Also Known As: RF Test, Rheumatoid Arthritis Factor Test

 The Collagen Cross-Linked N-Telopeptide (NTx) 24-Hour Urine Test measures the concentration of cross-linked N-telopeptides of type I collagen in the urine. These N-telopeptides are released during the natural process of bone resorption, where old bone tissue is broken down and its minerals released into the bloodstream.
: Urine

 The Collagen Cross-Linked N-Telopeptide Urine test, often abbreviated as NTx test, is designed to evaluate bone resorption. Bones in our body are constantly being remodeled - old bone is broken down (resorption) and new bone is formed. The collagen in bone contains cross-linked N-telopeptides that are released into the bloodstream during bone resorption and then excreted in urine. By measuring these N-telopeptides, the NTx test provides insights into the rate at which bone is being broken down.
: Random

The Collagen Type I C-Telopeptide (CTX) Test measures fragments of collagen released during bone breakdown. It is used as a marker of bone resorption to help assess bone health, monitor osteoporosis, and evaluate the effectiveness of treatments that affect bone metabolism.

: Serum
Also Known As: CTx Test

Most Popular

The Estradiol (E2) Test measures levels of estradiol, the primary form of estrogen, to evaluate reproductive and hormonal health. It helps assess menstrual irregularities, fertility issues, menopause status, and estrogen-producing disorders. In men, it aids in diagnosing hormonal imbalances. Doctors use the estradiol test to monitor hormone therapy, ovarian function, and conditions affecting puberty, bone health, and overall endocrine balance.

: Serum
Also Known As: E2 Test, Estrogen 2 Test

The Testosterone Free and Total Test measures total testosterone and free, bioavailable testosterone in blood for both men and women. It helps diagnose hormone imbalance, infertility, low libido, erectile dysfunction in men, irregular periods, or PCOS in women. Doctors also order it to assess fatigue, mood changes, or muscle weakness and to monitor hormone therapy. This test provides key insight into reproductive, endocrine, and overall metabolic health.

: Serum
Also Known As: Bound and Unbound Testosterone, Uncapped Testosterone Test

The Testosterone Free, Bioavailable, and Total Test measures total testosterone, free testosterone, and bioavailable testosterone, along with sex hormone binding globulin (SHBG) and albumin. It helps assess hormone status, reproductive health, and conditions affecting the endocrine system.

: Serum
Also Known As: Bound Unbound and Bioavailable Testosterone with SHBG Test, Uncapped Testosterone

The Testosterone Free and Total and Sex Hormone Binding Globulin (SHBG) Test measures total testosterone, free testosterone, and SHBG to assess hormone balance in men and women. It helps diagnose infertility, erectile dysfunction, low libido, irregular periods, PCOS, and abnormal puberty. Doctors also use it to evaluate fatigue, muscle weakness, or mood changes and to monitor hormone therapy. This test provides a comprehensive view of reproductive, endocrine, and metabolic health.

Also Known As: Bound and Unbound Testosterone with SHBG Test, Uncapped Testosterone Test

The Testosterone Total Male Test measures testosterone levels in men to assess reproductive, sexual, and hormonal health. It helps diagnose low testosterone (hypogonadism), infertility, and erectile dysfunction. Doctors use it to evaluate fatigue, muscle loss, or low libido and to monitor testosterone therapy, hormonal balance, bone health, and overall metabolism.

Patient must be male and 18 years of age or older.
: Serum
Also Known As: Total Male Testosterone Test

Most Popular

The T4 Total Test measures total thyroxine (T4) in blood, including both bound and free hormone, to assess thyroid function. Abnormal levels may indicate hypothyroidism, hyperthyroidism, goiter, or pituitary disorders. Doctors use this test to evaluate symptoms like fatigue, weight changes, hair loss, or irregular heart rate and to monitor thyroid replacement or antithyroid therapy. The T4 Total Test provides key insight into metabolic, hormonal, and endocrine health.

Also Known As: Total T4 Test, Total Thyroxine Test, T4 Test, Bound T4 Test

The Serum Protein Electrophoresis (SPEP) Test separates and measures proteins in the blood, including albumin and globulins. It helps detect abnormal protein levels linked to conditions such as multiple myeloma, lymphoma, chronic inflammation, liver disease, and immune disorders. This test provides important insights into overall protein balance and assists in diagnosing and monitoring various health conditions.

Also Known As: SPEP Test, Protein Total and Electrophoresis Test, Protein ELP Test, SPE Test, Serum Protein Electrophoresis Test

The Iron Total and Total Iron Binding Capacity (TIBC) Test measures iron levels in blood along with the blood’s ability to transport iron. It helps diagnose iron deficiency anemia, iron overload (hemochromatosis), and monitor nutritional or chronic health conditions. Low iron or high TIBC may indicate anemia, while high iron or low TIBC can suggest overload. Doctors use this test to evaluate fatigue, weakness, or other symptoms linked to iron and metabolic health.

: Serum
Also Known As: Serum Iron Test, Total Iron Binding Capacity Test, TIBC Test, UIBC Test

The Bilirubin Direct Test measures the level of direct (conjugated) bilirubin in the blood. It helps evaluate liver function and detect conditions such as bile duct obstruction, liver disease, or other disorders that affect how bilirubin is processed and removed from the body.

: Serum

Bones and joints play an integral role in the body. The bones provide a solid framework, and the joints and fluid in the joints work to keep the body mobile while working together with the soft tissue and muscles. Working together, they support the weight of the body.  

Unfortunately, the bones and joints may become weak. Let's examine some of the reasons that the bones and joints may become weak and the various reasons that may cause them to become weak.  

Afterwards, we'll learn why and how lab testing can help keep the joints, bones, and nervous system in peak condition.  

Factors That Affect Bones and Joints 

  • Aging - Over time, aging can lead to gradual weakening and deterioration of the bones and joints. 
  • Injury - Bones and or joints may become injured due to overexertion or an accident. 
  • Hereditary Factors - Genetic predisposition can cause the bones and joints ... See more