Cirrhosis

Cirrhosis is advanced scarring of the liver after years of ongoing injury. Common causes include viral hepatitis B or Cmetabolic/fatty liver diseasealcohol-related liver diseaseautoimmune conditions, and genetic disorders such as hemochromatosis or alpha-1 antitrypsin deficiency.

A proactive testing plan uses blood and urine labs to check liver injuryliver function, and complications, and to help uncover the cause. Core tests assess enzymes (injury pattern), synthetic function (album... See more

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The Comprehensive Metabolic Panel (CMP) Test measures 21 markers to assess metabolic health, liver and kidney function, and electrolyte balance. It includes glucose, calcium, sodium, potassium, chloride, CO2, albumin, globulin, A/G ratio, total protein, bilirubin, ALP, AST, ALT, BUN, creatinine, BUN/creatinine ratio, and eGFR. The CMP helps detect diabetes, liver or kidney disease, and supports routine screening and chronic condition monitoring.

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Also Known As: CMP Test, Chemistry Panel Test, Chem Test, Chem 21 Test, Chem 14 Test 

The Hepatic Function Panel Test measures liver enzymes, proteins, and bilirubin to assess liver health and function. It includes ALT, AST, ALP, albumin, total protein, and bilirubin levels. Abnormal results may indicate hepatitis, cirrhosis, fatty liver, or bile duct problems. Doctors use this test to investigate jaundice, nausea, abdominal pain, or fatigue and to monitor liver disease, alcohol use, or medication side effects affecting liver function.

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Also Known As: Liver Function Panel Test, LFT

The Liver Function Panel, also known as a Hepatic Function Panel, measures proteins, enzymes, and bilirubin to assess liver health and function. It helps detect liver disease, monitor liver conditions, and evaluate the effects of medications or other factors on liver performance.

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Also Known As: Hepatic Function Panel Test, HFP Test

The Complete Blood Count with Differential and Platelets Test is a comprehensive blood test that checks red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. The differential analyzes types of white blood cells to detect infections, anemia, clotting abnormalities, immune conditions, and certain cancers. This essential test is often ordered for routine health exams, diagnosis, and monitoring treatment progress.

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Also Known As: CBC Test, CBC with Differential and Platelets Test, CBC w/Diff and Platelets Test, Full Blood Count Test, Complete Blood Count Test

The Prothrombin Time with INR Test measures how long it takes blood to clot and calculates the international normalized ratio (INR) for accuracy. It is commonly used to monitor patients on blood-thinning medications like warfarin and to evaluate bleeding disorders, liver disease, or vitamin K deficiency. Doctors order this test to investigate easy bruising, frequent nosebleeds, or prolonged bleeding and to ensure safe and effective anticoagulant therapy.

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Also Known As: PT with INR Test

The Prothrombin with INR and Partial Thromboplastin Times Test measures how long blood takes to clot by evaluating PT, INR, and aPTT. Abnormal results may indicate clotting disorders, liver disease, vitamin K deficiency, or risk of bleeding and thrombosis. Doctors use this test to monitor patients on blood thinners like warfarin, assess unexplained bleeding, and evaluate clotting function. It provides critical insight into coagulation and overall blood health.

Also Known As: PT with INR and aPTT Test, PT/INR and PTT Test

The Activated Partial Thromboplastin Time (aPTT) Test measures how long it takes blood to clot, evaluating clotting factors and overall coagulation function. Abnormal results may indicate bleeding disorders, hemophilia, liver disease, or clotting factor deficiencies. Doctors also use this test to monitor patients on heparin therapy. Results provide essential insight into blood clotting, bleeding risk, and treatment management for safe medical care.

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Also Known As: aPTT Test, PTT Test

The Iron Total and Total Iron Binding Capacity (TIBC) Test measures iron levels in blood along with the blood’s ability to transport iron. It helps diagnose iron deficiency anemia, iron overload (hemochromatosis), and monitor nutritional or chronic health conditions. Low iron or high TIBC may indicate anemia, while high iron or low TIBC can suggest overload. Doctors use this test to evaluate fatigue, weakness, or other symptoms linked to iron and metabolic health.

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Also Known As: Serum Iron Test, Total Iron Binding Capacity Test, TIBC Test, UIBC Test

The Alpha-1-Antitrypsin Quantitative Test measures levels of alpha-1-antitrypsin (AAT), a protein that protects the lungs and liver from damage. Low levels may indicate alpha-1-antitrypsin deficiency, a genetic disorder linked to emphysema, COPD, and liver disease. Doctors use this test to investigate unexplained lung or liver problems, confirm hereditary AAT deficiency, and guide treatment or monitoring strategies for long-term health management.

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Also Known As: Alpha-1 Antitrypsin Test, A1AT Test, AAT Test, Alpha-1 Antitrypsin Serum Test

The Actin Smooth Muscle IgG Antibody Test detects autoantibodies against smooth muscle actin, often linked to autoimmune hepatitis and chronic liver disease. Elevated levels may indicate liver inflammation, cirrhosis, or other autoimmune conditions. Doctors use this blood test with liver panels and additional antibody tests to aid in diagnosis, monitor disease progression, and guide treatment decisions for patients with suspected autoimmune liver disorders.

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Also Known As: Actin IgG Antibody Test

The Copper Micronutrient Plasma Test measures copper levels in the blood to evaluate nutritional status and detect deficiencies or excess. Copper is essential for red blood cell formation, connective tissue health, energy production, and nervous and immune system function. This test helps identify imbalances from poor diet, malabsorption, or toxicity, supporting diagnosis and management of overall health.

Patient must be 18 years of age or older.
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The Copper Test measures copper levels in blood to evaluate nutritional status, liver function, and metabolic health. Abnormal levels may indicate Wilson’s disease, Menkes disease, liver disorders, or malnutrition. Both deficiency and excess copper can affect nervous system, immune function, and energy metabolism. Doctors use this test to investigate unexplained symptoms, monitor treatment, or assess copper-related disorders, providing key insight into overall health.

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Also Known As: Cu Test, Copper Serum Test, Copper Plasma Test

The Copper 24 Hour Urine Test evaluates copper elimination in urine across a full day, helping identify metabolic or liver-related disorders. Abnormal levels may signal Wilson’s disease, copper toxicity, or deficiency. By capturing copper output over 24 hours, the test provides insight into copper balance, aiding in the assessment of hepatic function, nutritional status, and the effects of excessive copper exposure.

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The Copper RBC Test measures copper levels inside red blood cells, reflecting long-term copper status and cellular availability. Unlike serum copper, which can fluctuate, RBC copper gives a more accurate picture of tissue stores. Abnormal results may indicate copper deficiency, malnutrition, malabsorption, Wilson’s disease, or excess copper exposure. Doctors use this test to evaluate metabolic health, monitor treatment, and support diagnosis of mineral imbalances.

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Also Known As: Cu RBC Test, Cu Test, Blood Copper Test, RBC Copper Test, Hepatic Copper Test, Copper Blood Test

The Mitochondria M2 IgG Antibody Test measures antibodies linked to autoimmune liver disease, particularly primary biliary cholangitis. These antibodies target mitochondrial enzymes in liver cells, helping to identify immune-related causes of chronic liver dysfunction. Providers use this test when investigating persistent fatigue, elevated liver enzymes, or suspected autoimmune involvement in bile duct damage.

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The Mitochondrial Antibody with Reflex to Titer Test detects antimitochondrial antibodies (AMAs), most commonly linked to primary biliary cholangitis (PBC), an autoimmune liver disease. If antibodies are present, reflex titers measure their level for greater diagnostic detail. Doctors use this test to investigate unexplained liver abnormalities, chronic fatigue, or jaundice, helping confirm autoimmune liver disease and guide long-term management.

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The Alpha-Fetoprotein (AFP) and AFP-L3 Test measures total AFP and the AFP-L3 fraction, which is more specific for liver cancer risk. Elevated AFP may indicate liver disease, germ cell tumors, or hepatitis, while AFP-L3 is strongly associated with hepatocellular carcinoma (HCC). Doctors order this test to assess liver function, screen high-risk patients, and monitor cancer treatment. Results provide critical insight into liver health and cancer detection.

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Also Known As: AFP Test, Total AFP Test, Alpha-Fetoprotein Tumor Markers, Alpha-Fetoprotein Test

The Ammonia Plasma Test measures ammonia levels in blood to evaluate liver function and metabolic health. Elevated ammonia may result from liver disease, cirrhosis, Reye’s syndrome, or urea cycle disorders, causing confusion or altered mental status. Doctors order this test for patients with unexplained behavioral changes, lethargy, or suspected hepatic encephalopathy. Results provide key insight into liver function, metabolic disorders, and treatment monitoring.

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Also Known As: NH3 Test, NH3 Plasma Test, Ammonia Blood Test

The Albumin Test measures albumin, the main protein made by the liver that maintains fluid balance and transports hormones, vitamins, and medications. Low albumin may indicate liver disease, kidney problems, malnutrition, or chronic inflammation, while high levels may reflect dehydration. Doctors order this test to evaluate swelling, fatigue, or abnormal labs. Results provide key insight into nutritional status, liver and kidney function, and overall metabolic health.

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Also Known As: ALB Test

The ALP Test measures alkaline phosphatase enzyme levels in blood to evaluate liver, bone, and bile duct health. High ALP may indicate liver disease, bile duct obstruction, bone disorders, or certain cancers, while low levels may suggest malnutrition or deficiency. Doctors order this test to investigate symptoms like fatigue, abdominal pain, or bone pain and often pair it with other liver function tests. Results provide key insight into metabolic and organ health.

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Also Known As: Alkaline Phosphatase Test, Alk Phos Test, Alkp Test

The ALT Test measures alanine aminotransferase, an enzyme mainly found in the liver. Elevated ALT may indicate liver damage from hepatitis, fatty liver disease, cirrhosis, alcohol use, or medication effects. Doctors order this test to evaluate symptoms such as fatigue, abdominal pain, or jaundice and often pair it with AST for accurate liver assessment. Results provide essential insight into liver health, enzyme activity, and overall metabolic function.

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Also Known As: Alanine Aminotransferase Test, GPT Test, SGPT Test, Serum Glutamic Pyruvic Transaminase Test

The AST Test measures aspartate aminotransferase, an enzyme found in the liver, heart, muscles, and other tissues. Elevated AST may indicate liver disease, heart attack, muscle injury, or other organ damage. Doctors order this test to evaluate symptoms such as fatigue, weakness, or jaundice and often pair it with ALT for accurate liver assessment. Results provide key insight into liver function, muscle health, and overall metabolic balance.

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Also Known As: Aspartate Aminotransferase Test, Serum Glutamic-Oxaloacetic Transaminase Test, SGOT Test

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The B-Type Natriuretic Peptide (BNP) Test measures BNP levels in blood to help diagnose and monitor heart failure and other cardiac conditions. High levels suggest the heart is under stress, often from congestive heart failure, hypertension, or heart disease. Doctors order this test for patients with shortness of breath, fatigue, or swelling. Results provide critical insight into heart function, guiding treatment and monitoring response to therapy.

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Also Known As: Brain Natriuretic Peptide Test

The Bilirubin Direct Test measures conjugated bilirubin in the blood to assess liver function and bile duct health. Elevated levels may indicate hepatitis, cirrhosis, gallstones, or bile duct obstruction, while low levels are generally normal. Doctors order this test for patients with jaundice, fatigue, or suspected liver disease. Results help diagnose and monitor liver disorders, guide treatment decisions, and evaluate overall hepatic and biliary health.

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Also Known As: Direct Bilirubin Test

The Fractionated Bilirubin Test separates total bilirubin into direct and indirect forms to assess liver and blood health. Elevated direct bilirubin may point to hepatitis, cirrhosis, or bile duct obstruction, while elevated indirect levels can signal hemolytic anemia or inherited disorders. Doctors order this test for jaundice, anemia, or suspected liver conditions. Results help guide diagnosis, treatment, and monitoring of liver and blood disorders.

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Also Known As: Fractionated Bilirubin Test

Cirrhosis occurs when healthy liver tissue gets damaged over a long period of time. Chronic liver disease leads to scarring of liver tissue, which affects the structure and functionality of the liver. Cirrhosis is linked to over 32,000 annual deaths in the United States alone.  

A wide variety of chronic liver conditions could be responsible for cirrhosis. It takes years or even decades to develop the condition. Compared to scars that occur in most of the other parts of the body, liver scarring is reversible – even in patients with cirrhosis. The liver is located on the upper right-hand side of your abdomen and is a vital organ in the body. It converts nutrients from food into vital blood components, metabolizes, detoxifies, and produces many factors that are necessary for blood clotting. The liver also produces bile for the digestion of fats. 

Liver disease can affect all these functions. Liver disease can occur due ... See more