Juvenile Rheumatoid Arthritis

Juvenile rheumatoid arthritis—now commonly called juvenile idiopathic arthritis (JIA)—is a group of autoimmune conditions that cause persistent joint inflammation in children and teens. Symptoms can include swollen, stiff, or painful joints; morning stiffness; and fatigue. Some subtypes involve fevers and rash (systemic JIA), eye inflammation (uveitis), or tendon/ligament pain (enthesitis).

Because signs can mimic infection, injury, or other autoimmune diseases, blood testing helps build the diagnostic picture and track disease activity over time. Ulta Lab Tests provides convenient access to pediatric-relevant arthritis ... See more

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The Rheumatoid Factor IgA IgG IgM Antibodies Test measures multiple rheumatoid factor classes to aid in diagnosing rheumatoid arthritis and related autoimmune diseases. Elevated levels may suggest joint inflammation, Sjögren’s syndrome, lupus, or chronic infections. Doctors use this comprehensive test to confirm autoimmune involvement, investigate persistent pain or stiffness, and guide treatment planning by assessing disease activity across antibody types.

Also Known As: RF Antibodies Test, Rheumatoid Arthritis Factor Antibodies Test

The Rheumatoid Factor IgA Antibody Test measures IgA-class rheumatoid factor, an autoantibody linked to rheumatoid arthritis and other autoimmune diseases. Elevated levels may indicate joint inflammation, Sjögren’s syndrome, or chronic infections. Doctors use this blood test alongside other markers to confirm diagnosis, assess disease activity, and guide treatment decisions for patients with suspected autoimmune or inflammatory disorders.

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Blood Draw
Also Known As: RF IgA Test, Rheumatoid Arthritis Factor IgA Antibody Test

The Rheumatoid Factor IgG Antibody Test measures IgG-class rheumatoid factor, an autoantibody often linked to rheumatoid arthritis and autoimmune diseases. Elevated levels may indicate joint inflammation, Sjögren’s syndrome, or chronic infection. Doctors use this test with other markers to confirm diagnosis, assess autoimmune activity, and guide treatment for patients with persistent joint pain, swelling, or suspected inflammatory disorders.

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Blood Draw
Also Known As: RF IgG Test, Rheumatoid Arthritis Factor IgG Antibody Test

The Rheumatoid Factor (RF) Test measures RF antibodies in blood to help diagnose rheumatoid arthritis and other autoimmune conditions. High RF levels may indicate rheumatoid arthritis, Sjögren’s syndrome, or other connective tissue diseases, though they can also appear in some infections. Doctors order this test to investigate joint pain, stiffness, or swelling. Results provide important insight into autoimmune activity, joint health, and inflammatory disease management.

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Also Known As: RF Test, Rheumatoid Arthritis Factor Test


The ANA Screen IFA with Reflex to Titer and Pattern Test detects antinuclear antibodies in blood to evaluate autoimmune activity. If positive, further testing identifies antibody concentration (titer) and fluorescence pattern, helping diagnose conditions like lupus, rheumatoid arthritis, or Sjögren’s syndrome. Doctors order this test to investigate symptoms such as joint pain, fatigue, rash, or swelling and to guide treatment for autoimmune and connective tissue disorders.

Also Known As: ANA Test, Antinuclear Antibody Screen Test


Most Popular

The Cyclic Citrullinated Peptide (CCP) IgG Antibody Test helps diagnose rheumatoid arthritis by detecting antibodies strongly linked to autoimmune joint disease. A positive result may indicate early or developing RA, even before symptoms appear. Doctors order this test for patients with joint pain, stiffness, or swelling. Results, often used with the rheumatoid factor (RF) test, provide valuable insight into autoimmune activity and long-term joint health management.

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Also Known As: Anti-CCP, Cyclic Citrullinated Peptide IgG Antibody Test

The HLA-B27 Antigen Test detects the presence of the HLA-B27 protein on white blood cells, which is linked to autoimmune conditions. A positive result may indicate higher risk for ankylosing spondylitis, reactive arthritis, or other spondyloarthropathies. Doctors order this test to investigate chronic back pain, joint inflammation, or autoimmune family history. Results provide critical insight into genetic predisposition, immune system activity, and inflammatory disease risk.

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The Complete Blood Count with Differential and Platelets Test is a comprehensive blood test that checks red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. The differential analyzes types of white blood cells to detect infections, anemia, clotting abnormalities, immune conditions, and certain cancers. This essential test is often ordered for routine health exams, diagnosis, and monitoring treatment progress.

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Also Known As: CBC Test, CBC with Differential and Platelets Test, CBC w/Diff and Platelets Test, Full Blood Count Test, Complete Blood Count Test

The Comprehensive Metabolic Panel (CMP) Test measures 21 markers to assess metabolic health, liver and kidney function, and electrolyte balance. It includes glucose, calcium, sodium, potassium, chloride, CO2, albumin, globulin, A/G ratio, total protein, bilirubin, ALP, AST, ALT, BUN, creatinine, BUN/creatinine ratio, and eGFR. The CMP helps detect diabetes, liver or kidney disease, and supports routine screening and chronic condition monitoring.

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Also Known As: CMP Test, Chemistry Panel Test, Chem Test, Chem 21 Test, Chem 14 Test 

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The Sed Rate Test, also called the ESR Test, measures how quickly red blood cells settle in a sample of blood. A faster rate may signal inflammation caused by infections, autoimmune diseases, arthritis, or other chronic conditions. Doctors use this test to investigate unexplained fever, joint pain, or muscle aches, and to monitor inflammatory disorders such as lupus or rheumatoid arthritis. The Sed Rate Test provides important insight into overall inflammatory activity.

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Also Known As: Erythrocyte Sedimentation Rate Test, ESR Test, Sedimentation Rate Test, Westergren Sedimentation Rate Test

The Cardiolipin IgA Antibody Test detects IgA antibodies to cardiolipin, helping assess clotting disorders, autoimmune disease, and vascular complications. High levels are often linked to antiphospholipid syndrome, pregnancy loss, or thrombotic conditions. This test provides insight into immune activity, coagulation balance, and systemic disorders influenced by antibody-mediated vascular dysfunction.

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The Cardiolipin IgG Antibody Test detects IgG antibodies to cardiolipin, often associated with autoimmune disease. Abnormal results may indicate antiphospholipid syndrome, blood clotting disorders, or pregnancy complications. This test provides insight into thrombotic risk, vascular health, systemic inflammation, and immune activity linked to autoimmune conditions and antibody-mediated disease.

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The Cardiolipin IgM Antibody Test measures IgM antibodies linked to antiphospholipid syndrome and autoimmune disorders. It helps evaluate unexplained blood clots, recurrent miscarriages, or abnormal clotting events. By detecting immune system activity against phospholipids, this test supports the assessment of vascular health, autoimmune activity, and risks related to thrombosis or systemic lupus erythematosus.

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The Complement Total CH50 Test measures overall activity of the complement system, a key part of the immune response that helps fight infections and regulate inflammation. Abnormal results may indicate autoimmune diseases such as lupus, complement deficiencies, or immune complex disorders. Doctors use this blood test to evaluate immune function, investigate recurrent infections, and monitor treatment in patients with suspected immune or autoimmune conditions.

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Also Known As: Total Complement Test, Total Complement Activity Test

The Lyme Disease IgG IgM Antibodies Immunoblot Test detects antibodies to Borrelia burgdorferi, the bacteria causing Lyme disease. IgM indicates recent infection, while IgG suggests past or ongoing infection. Doctors order this test to confirm exposure after ELISA screening or when symptoms such as rash, fatigue, joint pain, or neurological issues appear. Results provide critical insight for diagnosing and managing Lyme disease with greater accuracy.

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Also Known As: Borrelia burgdorferi Test, Lyme Disease Antibodies Test

The Protein Total and Albumin Test measures overall protein levels and albumin, the main blood protein made by the liver. Abnormal levels may indicate liver disease, kidney disorders, malnutrition, or chronic inflammation. Doctors order this test for patients with swelling, fatigue, or abnormal lab results. Results provide critical insight into nutritional status, liver and kidney function, and help guide diagnosis and treatment of metabolic or chronic conditions.

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The Salicylate Test measures salicylate levels in the blood to evaluate therapeutic use or potential toxicity from aspirin and related medications. Elevated concentrations may indicate overdose, metabolic disturbance, or risk of salicylate poisoning. This test supports monitoring in patients treated for pain, inflammation, or cardiovascular conditions and helps guide clinical management of suspected overdose cases.

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The Thiopurine Metabolites Test evaluates active metabolites of thiopurine drugs, including 6-thioguanine nucleotides and 6-methylmercaptopurine, to assess treatment effectiveness and safety. Elevated or low metabolite levels may indicate risk of toxicity, under-dosing, or non-adherence. This test provides critical insight for managing patients on immunosuppressive therapy, guiding personalized dosing, and monitoring long-term response.

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Also Known As: 6 MMP Test, 6 Tg Test

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Blood Draw, Phlebotomist

Juvenile Rheumatoid Arthritis (JRA) affects children under 16. It is an idiopathic disease with unknown causes. Arthritis is a disease in which the tendons and tissues of the body are badly affected by germs and viruses. It is an autoimmune disorder disease in which the immune system is damaged. White blood cells increase, and red blood cells decrease. The virus starts eating the tendons and tissues of the body without distinction, causing pain to parts of the body. The most affected parts are the joints which become stiff, painful, inflamed, and red.

JRA is the most common type of arthritis and affects more than 50,000 young adolescents in the United States.

Types 

There are six types of JRA:

Pauciarticular or Oligoarthritis

It affects four joints or fewer, affecting about half of the patients suffering from JRA. It targets knees, wrists, and eyes.

Polyarticular

It affects ... See more