All Liver Tests

All Liver Tests brings together the core blood tests that assess liver injurybile-flow (cholestasis), and liver function, while helping uncover common causes such as viral hepatitismetabolic/fatty liver diseasealcohol-related injuryautoimmune conditions, and genetic disorders. Early liver problems are often silent, so a proactive testing plan can identify issues before symptoms start.

Start with a hepatic function panelAST, ALT, alkaline ... See more

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The Alpha-1-Antitrypsin Quantitative Test measures levels of alpha-1-antitrypsin (AAT), a protein that protects the lungs and liver from damage. Low levels may indicate alpha-1-antitrypsin deficiency, a genetic disorder linked to emphysema, COPD, and liver disease. Doctors use this test to investigate unexplained lung or liver problems, confirm hereditary AAT deficiency, and guide treatment or monitoring strategies for long-term health management.

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Also Known As: Alpha-1 Antitrypsin Test, A1AT Test, AAT Test, Alpha-1 Antitrypsin Serum Test

The Alpha-Fetoprotein (AFP) and AFP-L3 Test measures total AFP and the AFP-L3 fraction, which is more specific for liver cancer risk. Elevated AFP may indicate liver disease, germ cell tumors, or hepatitis, while AFP-L3 is strongly associated with hepatocellular carcinoma (HCC). Doctors order this test to assess liver function, screen high-risk patients, and monitor cancer treatment. Results provide critical insight into liver health and cancer detection.

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Also Known As: AFP Test, Total AFP Test, Alpha-Fetoprotein Tumor Markers, Alpha-Fetoprotein Test

The ALT Test measures alanine aminotransferase, an enzyme mainly found in the liver. Elevated ALT may indicate liver damage from hepatitis, fatty liver disease, cirrhosis, alcohol use, or medication effects. Doctors order this test to evaluate symptoms such as fatigue, abdominal pain, or jaundice and often pair it with AST for accurate liver assessment. Results provide essential insight into liver health, enzyme activity, and overall metabolic function.

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Also Known As: Alanine Aminotransferase Test, GPT Test, SGPT Test, Serum Glutamic Pyruvic Transaminase Test

The Ammonia Plasma Test measures ammonia levels in blood to evaluate liver function and metabolic health. Elevated ammonia may result from liver disease, cirrhosis, Reye’s syndrome, or urea cycle disorders, causing confusion or altered mental status. Doctors order this test for patients with unexplained behavioral changes, lethargy, or suspected hepatic encephalopathy. Results provide key insight into liver function, metabolic disorders, and treatment monitoring.

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Also Known As: NH3 Test, NH3 Plasma Test, Ammonia Blood Test

The ANA Screen IFA with Reflex to Titer and Pattern Test detects antinuclear antibodies in blood to evaluate autoimmune activity. If positive, further testing identifies antibody concentration (titer) and fluorescence pattern, helping diagnose conditions like lupus, rheumatoid arthritis, or Sjögren’s syndrome. Doctors order this test to investigate symptoms such as joint pain, fatigue, rash, or swelling and to guide treatment for autoimmune and connective tissue disorders.

Also Known As: ANA Test, Antinuclear Antibody Screen Test

The ANA IFA Panel Comprehensive screens for autoimmune disorders by detecting antinuclear antibodies and specific markers including dsDNA, Sm, Sm/RNP, Scl-70, and Sjögren’s SS-A/SS-B. Doctors order this panel for patients with joint pain, rash, fatigue, or suspected lupus, scleroderma, or Sjögren’s syndrome. Results provide critical insight into autoimmune activity, helping confirm diagnosis, monitor disease progression, and guide treatment decisions.

Also Known As: Comprehensive ANA Panel

The ANCA Screen with Reflex to ANCA Titer detects antineutrophil cytoplasmic antibodies, often linked to autoimmune vasculitis such as granulomatosis with polyangiitis and microscopic polyangiitis. If the screen is positive, a titer is performed to measure antibody levels for greater diagnostic accuracy. Doctors use this test to evaluate unexplained inflammation, kidney or lung issues, and guide treatment decisions in autoimmune and systemic vasculitis care.

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Also Known As: ANCA Test, cANCA Test, pANCA Test, Serine Protease 3 Test, Acticytoplasmic Test, 3-ANCA test, PR3-ANCA Test, MPO-ANCA test

The AST Test measures aspartate aminotransferase, an enzyme found in the liver, heart, muscles, and other tissues. Elevated AST may indicate liver disease, heart attack, muscle injury, or other organ damage. Doctors order this test to evaluate symptoms such as fatigue, weakness, or jaundice and often pair it with ALT for accurate liver assessment. Results provide key insight into liver function, muscle health, and overall metabolic balance.

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Also Known As: Aspartate Aminotransferase Test, Serum Glutamic-Oxaloacetic Transaminase Test, SGOT Test

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The B-Type Natriuretic Peptide (BNP) Test measures BNP levels in blood to help diagnose and monitor heart failure and other cardiac conditions. High levels suggest the heart is under stress, often from congestive heart failure, hypertension, or heart disease. Doctors order this test for patients with shortness of breath, fatigue, or swelling. Results provide critical insight into heart function, guiding treatment and monitoring response to therapy.

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Also Known As: Brain Natriuretic Peptide Test

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The Bilirubin Direct Test measures conjugated bilirubin in the blood to assess liver function and bile duct health. Elevated levels may indicate hepatitis, cirrhosis, gallstones, or bile duct obstruction, while low levels are generally normal. Doctors order this test for patients with jaundice, fatigue, or suspected liver disease. Results help diagnose and monitor liver disorders, guide treatment decisions, and evaluate overall hepatic and biliary health.

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Also Known As: Direct Bilirubin Test

The Fractionated Bilirubin Test separates total bilirubin into direct and indirect forms to assess liver and blood health. Elevated direct bilirubin may point to hepatitis, cirrhosis, or bile duct obstruction, while elevated indirect levels can signal hemolytic anemia or inherited disorders. Doctors order this test for jaundice, anemia, or suspected liver conditions. Results help guide diagnosis, treatment, and monitoring of liver and blood disorders.

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Also Known As: Fractionated Bilirubin Test

The Bilirubin Total Test measures the overall level of bilirubin in blood to assess liver function, red blood cell breakdown, and bile duct health. Elevated bilirubin may cause jaundice and indicate hepatitis, cirrhosis, gallstones, or hemolytic anemia. Doctors order this test for patients with yellowing skin, fatigue, or abnormal liver results. Results provide essential insight into liver disease, blood disorders, and bile flow problems, guiding diagnosis and treatment.

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Also Known As: Total Bilirubin Test

The Neonatal Bilirubin Total Test evaluates the concentration of bilirubin in newborn blood, an important marker of liver processing and red blood cell breakdown. High bilirubin may cause neonatal jaundice and, in severe cases, lead to neurological complications. This test supports early detection, monitoring of bilirubin trends, and assessment of infant health during the newborn period.

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The BUN Creatinine Ratio Test compares blood urea nitrogen (BUN) to creatinine levels to assess kidney function and hydration status. A high ratio may indicate dehydration, gastrointestinal bleeding, or high protein intake, while a low ratio can suggest liver disease or malnutrition. Doctors order this test with kidney panels to evaluate fatigue, swelling, or abnormal lab results. Results help diagnose renal issues and guide treatment planning.

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Also Known As: Blood Urea Nitrogen to Creatinine Ratio

The C-Reactive Protein (CRP) Test measures CRP levels in blood to detect inflammation in the body. Elevated CRP may indicate infections, autoimmune disorders, or chronic diseases such as arthritis, cardiovascular disease, or inflammatory bowel disease. Doctors use this test to assess acute illness, monitor treatment response, and evaluate risk for heart disease. The CRP test provides key insight into inflammation, immune health, and overall wellness.

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Also Known As: CRP Test, Inflammation Test

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The CA 19-9 Test measures levels of carbohydrate antigen 19-9 in blood, a tumor marker often elevated in pancreatic cancer and sometimes in bile duct, colorectal, or liver cancers. While not used alone for diagnosis, it helps monitor treatment, track disease progression, and detect recurrence. Elevated CA 19-9 may also occur in noncancerous conditions. Doctors use this test to support cancer management and guide therapy decisions.

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Also Known As: CA 19-9 Tumor Marker, Cancer Antigen 19-9 Test

The Cardio IQ™ Fibrinogen Antigen Test evaluates fibrinogen concentration, a key protein that influences clotting and cardiovascular disease risk. It provides insight into vascular inflammation, atherosclerosis, and thrombotic events. This test helps identify factors that contribute to stroke, coronary artery disease, and systemic vascular complications, offering valuable information for assessing overall cardiovascular health.

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Also Known As: Fibrinogen Antigen Nephelometry Test

The Cardio IQ™ Triglycerides Test measures triglyceride levels in the blood, an important marker of lipid metabolism and cardiovascular health. Elevated triglycerides are linked to increased risk of heart disease, pancreatitis, and metabolic syndrome. Physicians use this test to assess risk factors, monitor therapy response, and guide lifestyle or treatment decisions, often as part of a broader lipid or heart health evaluation.

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The Cardio IQ Vitamin D test, also known as a 25-hydroxy vitamin D test, measures the levels of total vitamin D in the blood, including both vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). It provides information about an individual's overall vitamin D status.

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Also Known As: Ergocalciferol Test, Vitamin D2 Test, Cholecalciferol Test, Vitamin D3 Test, Calcidiol Test, 25-hydroxyvitamin D Test, Calcifidiol Test, 25-hydroxy-vitamin D Test

The Catecholamines Fractionated Plasma Test measures plasma levels of dopamine, epinephrine, and norepinephrine, hormones that regulate stress response, blood pressure, and heart rate. Elevated levels may indicate pheochromocytoma, paraganglioma, or other adrenal and nervous system disorders. Doctors use this test to investigate symptoms like hypertension, headaches, sweating, or palpitations, and to monitor treatment of adrenal tumors.

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The CEA Test measures carcinoembryonic antigen levels in blood, a protein that may be elevated in certain cancers, especially colorectal, pancreatic, lung, breast, or ovarian cancer. It is not used alone for diagnosis but helps monitor cancer treatment, detect recurrence, and track disease progression. Elevated CEA can also occur in noncancerous conditions. Doctors use this test to support therapy decisions and provide insight into cancer management.

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Also Known As: Carcinoembryonic Antigen Test

The Ceruloplasmin Test measures levels of ceruloplasmin, a copper-carrying protein made in the liver, to evaluate copper metabolism and related disorders. Low levels may indicate Wilson’s disease, Menkes disease, or severe liver disease, while high levels may suggest inflammation or pregnancy. Doctors order this test for patients with liver problems, neurological symptoms, or abnormal copper levels. Results help diagnose metabolic disorders and guide treatment.

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Also Known As: Copper Oxide Test, Wilson’s Disease Test

Nearly 4.5 million Americans — almost 1 in every 50 — live with liver disease. Are you one of them? If you're not sure, it might be time to order a liver function test.

A hepatic function panel tests how well your liver is working. Taking the initiative to check your liver function before noticing a problem could help you avoid serious health issues. 

Keep reading to learn what a hepatic function panel is, how it can help you catch health issues early, and how you can order it yourself online. 

What is a Decline in Hepatic Function?

Your liver is your body's hard-working multitasker. It performs many crucial functions, including:

  • Monitoring and regulating chemicals in your blood
  • Cleaning toxins from your blood
  • Performing functions with your immune system
  • Storing energy in the form of glycogen
  • Helping break down fatty food
  • Breaking down old red blood cells

Your ... See more

Jaundice, also called icterus, is a condition where the skin, the whites of the eyes, and even body fluids turn significantly yellow following an increase in the levels of bilirubin in the blood. Bilirubin is a yellowish substance that forms from the normal breakdown of red blood cells (or RBCs). Red blood cells normally live for about 120 days before being broken down by the body, a process that results in the formation of bilirubin. Bilirubin is then transported to the liver where it is metabolized and excreted in bile. Bile is a yellow-green-to-brown fluid that is released into the duodenum to help in the digestion of lipids and the elimination of waste substances like bilirubin and excess cholesterol. Changes to the normal metabolism process or overproduction of bilirubin may lead to jaundice. 

Jaundice is not an illness, per se. Rather, it is a medical condition that may indicate an underlying liver, pancreas, or gallbladder problem. Jaundice can be ... See more