Depression

Depression is a clinical condition, but many medical issues can mimic or worsen depressive symptoms—including thyroid disease, anemia, vitamin and iron deficiencies, diabetes, hormone changes, infections, and some medicines or substances. Blood testing does not diagnose depression itself; instead, it helps find reversible contributors, establish baselines before or during treatment, and monitor overall health.

A proactive plan usually starts with CBC/CMPthyroid (TSH ± Free T4)vitamin B12 with methylmalonic acid (MMA)vitamin ... See more

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The Vitamin B12 and Folate Panel Test measures blood levels of vitamin B12 and folate to evaluate nutritional status, red blood cell production, and nervous system health. Deficiencies may cause anemia, fatigue, weakness, neuropathy, or cognitive decline, while elevated levels can indicate liver or kidney disease. Doctors use this panel to diagnose deficiency, monitor therapy, and assess absorption disorders such as pernicious anemia, Crohn’s disease, or celiac disease.

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Also Known As: Cobalamin and Folic Acid Test, Vitamin B12 and Vitamin B9 Test

The Vitamin C Micronutrient Test measures blood levels of ascorbic acid to assess nutritional status and detect deficiencies. Vitamin C is vital for immune defense, collagen formation, wound healing, and antioxidant protection. This test helps identify poor dietary intake, absorption issues, or increased needs due to illness or stress, supporting diagnosis and management of overall health.

Patient must be 18 years of age or older.
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Also Known As: Ascorbic Acid Test

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The Vitamin C Test measures blood levels of vitamin C (ascorbic acid), an essential nutrient for immune defense, wound healing, collagen production, and antioxidant protection. Low levels may indicate poor diet, malabsorption, or scurvy, while high levels may occur with excess supplementation. Doctors order this test for patients with fatigue, bleeding gums, or poor wound healing. Results help assess nutritional status and guide treatment or dietary adjustments.

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Also Known As: Ascorbic Acid Test

The Vitamin D 1,25-Dihydroxy Test measures the active form of vitamin D in blood to evaluate calcium and phosphorus balance, bone health, and kidney function. Abnormal levels may indicate kidney disease, parathyroid disorders, or problems with calcium metabolism. Doctors order this test when deficiency symptoms don’t match 25-hydroxy vitamin D results or to monitor chronic illness. Results provide vital insight into vitamin D activity, mineral health, and metabolic function.

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Also Known As: Calcitriol Test

The Vitamin D 25-Hydroxy Total Test measures levels of 25-hydroxyvitamin D in blood to evaluate vitamin D status, bone health, and calcium balance. It helps detect deficiency, insufficiency, or toxicity, which can affect immune function, muscle strength, and risk of osteoporosis. Doctors use this test to assess overall nutritional health, monitor supplementation, and support diagnosis of metabolic or endocrine disorders linked to vitamin D.

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Also Known As: 25-hydroxyvitamin D Test, Vitamin D 25-OH Test, Total 25-OH D Test

The QuestAssureD™ Vitamin D 25-Hydroxy Total Test measures Vitamin D2, Vitamin D3, and total 25-hydroxy vitamin D to assess overall vitamin D status. Adequate vitamin D supports bone strength, calcium absorption, immune health, and muscle function. Low levels may cause osteoporosis, weakness, or increased disease risk, while high levels can indicate toxicity. Doctors use this test to diagnose deficiency, monitor supplementation, and evaluate metabolic and endocrine health.

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Also Known As: Vitamin D Test, Ergocalciferol Test, Vitamin D2 Test, Cholecalciferol Test, Vitamin D3 Test, Calcidiol Test, 25-hydroxyvitamin D Test, Calcifidiol Test, 25-hydroxy-vitamin D Test, Vitamin D Total Test

The Zinc Micronutrient Test measures blood zinc levels to evaluate nutritional status and detect deficiencies or excess. Zinc is vital for immune function, wound healing, growth, reproduction, and enzyme activity. This test helps identify poor intake, malabsorption, or excessive supplementation, supporting diagnosis and management of overall health, immune balance, and metabolic function.

Patient must be 18 years of age or older.
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Also Known As: Zinc Plasma Test

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The Zinc Test measures zinc levels in blood to evaluate nutritional status and overall health. Zinc is essential for immune function, wound healing, growth, taste, and reproductive health. Abnormal levels may cause fatigue, hair loss, delayed healing, or increased infection risk. Doctors use this test to detect zinc deficiency or excess, monitor supplementation, and guide treatment for conditions linked to immune, metabolic, or endocrine imbalance.

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Also Known As:  Zinc Plasma Test, Zn Test

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Depression afflicts 264 million people across the world.

Amid a pandemic and other traumatic events, mental health is now more important than ever.

You may have down moments, but what if you're not sure if you actually have depression? Or maybe you are certain you are suffering from depression, but don't know why.

Depression can be caused by external factors, but it can also stem from other health issues. Depression blood tests may help you narrow down the cause so you can start working on a solution.

Here is what you need to know about depression and how lab tests for depression can help.

What Is Depression?

At its most simple description, depression causes feelings of sadness. It also causes you to lose interest in people or activities that you previously cared about. Depression is common, but that doesn't take away from the severity of this affliction.

Depression can interfere with personal relationships, work, ... See more