Epstein-Barr Virus (EBV) Save 20% to 30%

Save 20% to 30% on select Epstein-Barr Virus (EBV) panels. Use promo code: ULTAC845

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  • ULTAC845

Epstein-Barr Virus (EBV) Antibody Panel

Includes: Epstein-Barr Virus VCA Antibody (IgM), Epstein-Barr Virus VCA Antibody (IgG), Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody (IgG)

Clinical Significance: Primary infection by EBV causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders including tumors. VCA-IgM is typically detectable at clinical presentation, then declines to undetectable levels within a month in young children and within 3 months in other individuals. VCA-IgG is typically detectable at clinical presentation, and persists for life. EBNA IgG typically appears during convalescence (3-4 months after clinical presentation) and remains detectable for life.

EBV-VCA IgG/IgM (viral capsid antigen): A positive IgG means you’ve had or currently have the infection; A positive IgM means the virus has been reactivated.

EBV-EBNA IgG (nuclear antigen): A positive test result is usually associated with past infections.

Reference Range(s)

Epstein-Barr Virus VCA Antibody (IgM)

U/mLInterpretation

  • <36.00 Negative
  • 36.00-43.99Equivocal
  • >43.99Positive


Epstein-Barr Virus VCA Antibody (IgG)

U/mLInterpretation

  • <18.00 Negative
  • 18.00-21.99Equivocal
  • >21.99Positive


Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody (IgG)

U/mLInterpretation

  • <18.00 Negative
  • 18.00-21.99Equivocal
  • >21.99Positive

Alternative Name(s)

EBV Comprehensive,Infectious Mononucleosis Panel

 


Clinical Significance

Primary infection by EBV causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders including tumors. IgG recognizing Early Antigen D typically appears within a month after clinical presentation and is transient, lasting only 3-4 months. Persistently elevated levels suggest reactivation or persistence of EBV infection.

The Epstein-Barr EBV Early Antigen D Ab IgG test that will let one know if the virus is actively replicating.


For the most comprehensive look at your biomarkers for Epstein-Barr (EBV), we recommend the Epstein-Barr (EBV) Comprehensive Panel, as only one may come out positive:

  • EBV-VCA IgG/IgM (viral capsid antigen): A positive IgG means you’ve had or currently have the infection; A positive IgM means the virus has been reactivated.
  • EBV-EBNA IgG (nuclear antigen): A positive test result is usually associated with past infections.
  • EBV-EA-D IgG (early antigen): A positive EA IgG may mean you have an active or reactivated infection.
  • The Epstein-Barr EBV Early Antigen D Ab IgG test that will let one know if the virus is actively replicating.

Epstein-Barr (EBV) is a virus that causes mononucleosis, also known as the kissing disease, is a viral infection that is thought to be transmitted through the saliva of those who are infected. The Epstein-Barr virus creates an inactive infection in the body where it lies dormant. It can awaken and reactivate itself, even many years after its initial activation.

The reactivated virus has the potential to induce many debilitating autoimmune symptoms. In some, the infection may not be adequately suppressed and may cause or exacerbate autoimmune diseases. 

The Epstein-Barr (EBV) tests are used to figure out if a person has a reactivated infection. 

Reference Range(s)

Epstein-Barr Virus VCA Antibody (IgM)

U/mLInterpretation

  • <36.00 Negative
  • 36.00-43.99 Equivocal
  • >43.99 Positive

Epstein-Barr Virus VCA Antibody (IgG)

U/mLInterpretation

  • <18.00 Negative
  • 18.00-21.99 Equivocal
  • >21.99 Positive


Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody (IgG)

U/mLInterpretation

  • <18.00 Negative
  • 18.00-21.99 Equivocal
  • >21.99 Positive

Epstein-Barr Virus Early Antigen D Antibody (IgG)

U/mLInterpretation

  • <9.00 Negative
  • 9.00-10.99 Equivocal
  • >10.99 Positive