Fibromyalgia

Fibromyalgia is a chronic pain condition marked by widespread musculoskeletal painfatigueunrefreshing sleep, and cognitive symptoms (“brain fog”). There is no single blood test that diagnoses fibromyalgia. Diagnosis is clinical, based on symptom patterns and duration.
Lab testing still plays a critical role. It helps exclude look-alike conditions (such as thyroid disease, inflammatory arthritis, myopathy, anemia/iron deficiency, and vitamin deficiencies), identify coexisting problems that ... See more

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The ANA Screen IFA with Reflex to Titer and Pattern Test detects antinuclear antibodies in blood to evaluate autoimmune activity. If positive, further testing identifies antibody concentration (titer) and fluorescence pattern, helping diagnose conditions like lupus, rheumatoid arthritis, or Sjögren’s syndrome. Doctors order this test to investigate symptoms such as joint pain, fatigue, rash, or swelling and to guide treatment for autoimmune and connective tissue disorders.

Also Known As: ANA Test, Antinuclear Antibody Screen Test

The Cardio IQ Vitamin D test, also known as a 25-hydroxy vitamin D test, measures the levels of total vitamin D in the blood, including both vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). It provides information about an individual's overall vitamin D status.

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Also Known As: Ergocalciferol Test, Vitamin D2 Test, Cholecalciferol Test, Vitamin D3 Test, Calcidiol Test, 25-hydroxyvitamin D Test, Calcifidiol Test, 25-hydroxy-vitamin D Test

The Celiac Disease Comprehensive Panel screens for celiac disease by measuring Tissue Transglutaminase (tTG) Antibody IgA and total IgA. If tTG IgA is positive, an Endomysial Antibody Screen IgA is added for confirmation. If IgA levels are low, tTG IgG is performed to ensure accurate detection. Doctors use this blood panel to identify gluten sensitivity, confirm diagnosis, and guide treatment for patients with suspected celiac disease.

Also Known As: Comprehensive Celiac Disease Panel, Celiac Disease Test

The Complete Blood Count with Differential and Platelets Test is a comprehensive blood test that checks red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. The differential analyzes types of white blood cells to detect infections, anemia, clotting abnormalities, immune conditions, and certain cancers. This essential test is often ordered for routine health exams, diagnosis, and monitoring treatment progress.

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Also Known As: CBC Test, CBC with Differential and Platelets Test, CBC w/Diff and Platelets Test, Full Blood Count Test, Complete Blood Count Test

The Comprehensive Metabolic Panel (CMP) Test measures 21 markers to assess metabolic health, liver and kidney function, and electrolyte balance. It includes glucose, calcium, sodium, potassium, chloride, CO2, albumin, globulin, A/G ratio, total protein, bilirubin, ALP, AST, ALT, BUN, creatinine, BUN/creatinine ratio, and eGFR. The CMP helps detect diabetes, liver or kidney disease, and supports routine screening and chronic condition monitoring.

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Also Known As: CMP Test, Chemistry Panel Test, Chem Test, Chem 21 Test, Chem 14 Test 

The Creatine Kinase (CK) Total Test measures CK enzyme levels in blood to detect muscle injury, inflammation, or stress. Elevated CK may indicate muscle disorders, heart attack, strenuous exercise, or conditions such as rhabdomyolysis, while low levels are less common. Doctors use this test to evaluate unexplained muscle pain, weakness, or chest pain and to monitor recovery. It provides insight into muscle, cardiac, and overall metabolic health.

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Also Known As: CK Total Test, Creatine Phosphokinase, CPK Test

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The Cyclic Citrullinated Peptide (CCP) IgG Antibody Test helps diagnose rheumatoid arthritis by detecting antibodies strongly linked to autoimmune joint disease. A positive result may indicate early or developing RA, even before symptoms appear. Doctors order this test for patients with joint pain, stiffness, or swelling. Results, often used with the rheumatoid factor (RF) test, provide valuable insight into autoimmune activity and long-term joint health management.

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Also Known As: Anti-CCP, Cyclic Citrullinated Peptide IgG Antibody Test

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The QuestAssureD™ Vitamin D 25-Hydroxy Total Test for Infants measures total vitamin D levels to evaluate bone health, calcium balance, and overall growth. Adequate vitamin D is essential for skeletal development, immune function, and preventing rickets. Physicians use this test to identify deficiency, monitor supplementation, and ensure infants receive the nutrients needed for proper development and long-term health.

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The Rheumatoid Factor (RF) Test measures RF antibodies in blood to help diagnose rheumatoid arthritis and other autoimmune conditions. High RF levels may indicate rheumatoid arthritis, Sjögren’s syndrome, or other connective tissue diseases, though they can also appear in some infections. Doctors order this test to investigate joint pain, stiffness, or swelling. Results provide important insight into autoimmune activity, joint health, and inflammatory disease management.

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Also Known As: RF Test, Rheumatoid Arthritis Factor Test

The Rheumatoid Factor IgA Antibody Test measures IgA-class rheumatoid factor, an autoantibody linked to rheumatoid arthritis and other autoimmune diseases. Elevated levels may indicate joint inflammation, Sjögren’s syndrome, or chronic infections. Doctors use this blood test alongside other markers to confirm diagnosis, assess disease activity, and guide treatment decisions for patients with suspected autoimmune or inflammatory disorders.

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Also Known As: RF IgA Test, Rheumatoid Arthritis Factor IgA Antibody Test

The Rheumatoid Factor IgG Antibody Test measures IgG-class rheumatoid factor, an autoantibody often linked to rheumatoid arthritis and autoimmune diseases. Elevated levels may indicate joint inflammation, Sjögren’s syndrome, or chronic infection. Doctors use this test with other markers to confirm diagnosis, assess autoimmune activity, and guide treatment for patients with persistent joint pain, swelling, or suspected inflammatory disorders.

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Also Known As: RF IgG Test, Rheumatoid Arthritis Factor IgG Antibody Test

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The Sed Rate Test, also called the ESR Test, measures how quickly red blood cells settle in a sample of blood. A faster rate may signal inflammation caused by infections, autoimmune diseases, arthritis, or other chronic conditions. Doctors use this test to investigate unexplained fever, joint pain, or muscle aches, and to monitor inflammatory disorders such as lupus or rheumatoid arthritis. The Sed Rate Test provides important insight into overall inflammatory activity.

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Also Known As: Erythrocyte Sedimentation Rate Test, ESR Test, Sedimentation Rate Test, Westergren Sedimentation Rate Test

The Striated Muscle Antibody Test with Reflex to Titer detects antibodies targeting striated muscle, often linked to autoimmune conditions and paraneoplastic syndromes. Elevated levels may indicate myasthenia gravis, thymoma, or other neuromuscular disorders. Reflex titers help assess antibody concentration, supporting diagnosis, monitoring disease activity, and guiding evaluation of immune-mediated muscle weakness.

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The T3 Reverse (rT3) Test measures reverse triiodothyronine, an inactive thyroid hormone, to assess thyroid and metabolic function. High rT3 may occur in hypothyroidism, chronic illness, stress, or during certain treatments, while low levels may reflect hormone imbalance. Doctors use this test along with TSH, Free T4, and Free T3 to evaluate fatigue, weight changes, or slow metabolism. The rT3 Test provides insight into thyroid regulation, energy balance, and endocrine health.

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Also Known As: Reverse T3 Test, RT3 Test, T3R Test

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The T3 Total Test measures total triiodothyronine (T3), a combination of both bound and unbound (free) T3, to assess thyroid function. Abnormal levels may indicate hyperthyroidism, hypothyroidism, goiter, or pituitary disorders. Doctors use this test to evaluate symptoms like fatigue, weight changes, anxiety, or irregular heartbeat and to monitor thyroid treatment. The T3 Total Test provides essential insight into metabolism, energy regulation, and overall endocrine health.

Also Known As: Total T3 Test, Total Triiodothyronine Test, T3 Test, Bound and Unbound T3

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The T3 Free Test measures free triiodothyronine (T3), the active thyroid hormone not bound to proteins, to assess thyroid function. It helps diagnose hyperthyroidism, hypothyroidism, goiter, and pituitary disorders. Doctors order this test to evaluate symptoms like fatigue, weight changes, anxiety, or irregular heartbeat and to monitor thyroid replacement or antithyroid therapy. The Free T3 Test provides key insight into metabolism, energy regulation, and overall endocrine health.

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Also Known As: Free T3 Test, Free Triiodothyronine Test, FT3 Test, T3F Test, Unbound T3 Test

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The T4 Total Test measures total thyroxine (T4) in blood, a combination of both bound and unbound (free) T4, to assess thyroid function. Abnormal levels may indicate hypothyroidism, hyperthyroidism, goiter, or pituitary disorders. Doctors use this test to evaluate symptoms like fatigue, weight changes, hair loss, or irregular heart rate and to monitor thyroid replacement or antithyroid therapy. The T4 Total Test provides key insight into metabolic, hormonal, and endocrine health.

Also Known As: Total T4 Test, Total Thyroxine Test, T4 Test, Bound and Unbound T4 Test

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The T4 Free Test measures the level of free thyroxine (T4) in blood, the active thyroid hormone not bound to proteins. It helps diagnose thyroid disorders such as hypothyroidism, hyperthyroidism, and goiter, as well as pituitary conditions affecting hormone regulation. Doctors use this test to evaluate symptoms like fatigue, weight changes, hair loss, or irregular heartbeat and to monitor thyroid replacement or antithyroid therapy, providing insight into metabolic and endocrine health.

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Also Known As: Free T4 Test, Free Thyroxine Test, FT4 Test, T4F Test, Unbound T4 Test

The Thyroid Peroxidase and Thyroglobulin Antibodies Test measures TPO and TgAb antibodies that target thyroid enzymes and proteins essential for hormone production. High levels are linked to autoimmune thyroid disorders such as Hashimoto’s thyroiditis and Graves’ disease. Doctors order this test to evaluate fatigue, weight changes, neck swelling, or irregular heartbeat and to confirm thyroid autoimmunity. It provides vital insight into thyroid function and endocrine health.

Also Known As: Thyroid Antibodies Test, TPO and TgAb Test

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The Thyroid Stimulating Hormone (TSH) Test measures TSH levels in blood to assess thyroid function and diagnose hypothyroidism or hyperthyroidism. It evaluates how the thyroid controls metabolism, energy, weight, and heart rate. Doctors use the TSH test to investigate symptoms such as fatigue, hair loss, or mood changes. Frequently included in routine health exams, it is also key for monitoring thyroid disease treatment and overall endocrine balance.

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Also Known As: Thyroid Stimulating Hormone Test, Thyrotropin Test

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The Thyroid Stimulating Immunoglobulin (TSI) Test detects antibodies that stimulate the thyroid gland, often causing hyperthyroidism and Graves’ disease. High TSI levels may lead to symptoms such as weight loss, rapid heartbeat, or eye problems. Doctors order this test to confirm Graves’ disease, monitor treatment, or assess relapse risk. Results provide essential insight into autoimmune thyroid disorders and guide personalized management strategies.

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Also Known As: Thyroid Stimulating Immunoglobulin Test

The Vitamin D 25-Hydroxy Total Test measures levels of 25-hydroxyvitamin D in blood to evaluate vitamin D status, bone health, and calcium balance. It helps detect deficiency, insufficiency, or toxicity, which can affect immune function, muscle strength, and risk of osteoporosis. Doctors use this test to assess overall nutritional health, monitor supplementation, and support diagnosis of metabolic or endocrine disorders linked to vitamin D.

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Also Known As: 25-hydroxyvitamin D Test, Vitamin D 25-OH Test, Total 25-OH D Test

The QuestAssureD™ Vitamin D 25-Hydroxy Total Test measures Vitamin D2, Vitamin D3, and total 25-hydroxy vitamin D to assess overall vitamin D status. Adequate vitamin D supports bone strength, calcium absorption, immune health, and muscle function. Low levels may cause osteoporosis, weakness, or increased disease risk, while high levels can indicate toxicity. Doctors use this test to diagnose deficiency, monitor supplementation, and evaluate metabolic and endocrine health.

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Also Known As: Vitamin D Test, Ergocalciferol Test, Vitamin D2 Test, Cholecalciferol Test, Vitamin D3 Test, Calcidiol Test, 25-hydroxyvitamin D Test, Calcifidiol Test, 25-hydroxy-vitamin D Test, Vitamin D Total Test

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Fibromyalgia is a disease about which much is not yet known. Because of the nature of the symptoms, it is often misdiagnosed as other conditions. For this reason, fibromyalgia tests can be a good idea for those who suspect they may be suffering from this condition.

If you suspect that you may have this disorder, you will want to learn more about some of the fibromyalgia lab tests that are available to you. Read on to find out about the symptoms, causes, management, and diagnosis of this disease.

Fibromyalgia Lab Tests

For some time, there was no known way to test specifically for fibromyalgia. For this reason, diagnosis often consists of testing to rule out other diseases. Doctors most often identify a condition as fibromyalgia by process of elimination.

Some of the diseases that have similar symptoms to fibromyalgia include hypothyroidism, chronic ... See more