The Helicobacter Pylori Ag, Eia, Stool test contains 1 test with 1 biomarker.
Helicobacter Pylori Ag, Eia, Stool
IMPORTANT: Patient Self Collection Required - Instructions
- Patient to visit a Quest Patient Service Center to obtain the designated sterile collection container required for the test.
- Patient self-collects stool sample off site from PSC.
- Patient self-collects 0.5 mL or 0.5 grams of semi-solid stool or 20 mm diameter solid stool and transfer to properly labeled plastic, leak-proof container.
- Label the specimen collection container:
- Record the date and time on the specimen collection.
- Record the patients full name as on requisition and DOB.
- IMPORTANT: Watery, diarrheal stool is not acceptable.
- IMPORTANT: The stool sample must be refrigerated immediately after collection.
- The stool specimen must be packed with cold packs and returned to the Quest Patient Service Center with the Patient Requisition within 24 hours of collection.
Patient Preparation
For initial diagnostic purposes no special patient preparation is required. Patients are not required to be off of medications or to fast before this test. While positive test results from patients taking agents such as proton pump inhibitors and antimicrobials should be considered accurate, false negative results may be obtained. For this reason, physicians may suggest the patient go off medications for two weeks and repeat test if negative results are obtained.
To confirm eradication, testing should be done at least 4 weeks following the completion of treatment. However, a positive test result 7 days’ post therapy is indicative of treatment failure.
Clinical Background
Helicobacter pylori infection has been associated with duodenal and gastric ulcers and chronic active, chronic persistent, and atrophic gastritis in adults and children. Infected persons have a 2- to 6-fold increased risk of developing gastric cancer and mucosal-associated-lymphoid-type (MALT) lymphoma.
Noninvasive Assays
The UBT and stool antigen test are highly sensitive and specific for H pylori infection. These assays have been recommended by the American Gastroenterological Association (AGA) and the American College of Gastroenterologists (ACG) as the most accurate noninvasive tests for diagnosis of H pylori infection and for confirmation of eradication after therapy.