Metabolism

Want to know what's going on inside you? 

Metabolism lab testing can identify health issues and assess your body's chemical balance and energy utilization.

Metabolism Lab Testing can help you learn about your body and uncover health problems. It's a simple blood test that tells you about your metabolism and how your body consumes food and energy. For example, vitamin or hormone imbalances can cause symptoms like exhaustion, weight gain, lack of sex desire, hair loss, or muscular pains. If you have diabetes, high cholesterol, or hypertension, this test will help you determine if particular medications are helpful for you. Our tests detect insulin resistance, which is linked to metabolic syndrome (a combination of risk factors that increase the chance of developing heart disease, stroke, and diabetes).

If you notice an imbalance in one of these areas, you may take proactive steps to correct the condition. We provide discounted lab testing packages so you can obtain all the information you need without breaking your budget. Because we partner with Quest Diagnostics laboratories across the United States, you have options for where your specimen is collected and when you receive your results - wherever life takes you!

To get the right test for you, choose from the selections below.

For additional information on Metabolism and Lab Testing, click here.

 


Name Matches

Metabolic Discovery Comprehensive Panel

This thorough set of tests helps assess your metabolism. Are you storing too much fat and sugar or perhaps too little? Are you insulin resistant with subsequent inflammation? You can run this panel to discover whether your diet, fitness and nutritional habits are providing you the metabolic health and longevity you deserve. Don’t settle for one-size-fits-all health advice.

Preparation: Fast for 10-16 hours, overnight. Drink enough water and take your prescribed medications. No coffee or vigorous exercise on the morning of the blood draw.

CONTAINS ALL OF THE TESTS IN THE Metabolic Discovery Panel

  • CBC (includes Differential and Platelets)
  • Comprehensive Metabolic Panel (CMP)
  • Ferritin
  • Hemoglobin A1c with eAG
  • Insulin
  • Lipid Panel with Ratios
  • Vitamin B12 (Cobalamin)
  • Vitamin D, 25-Hydroxy, Total, Immunoassay

PLUS

  • Adiponectin 
  • Iron and Total Iron Binding Capacity (TIBC)
  • Leptin
  • T3, Free
  • T4, Free
  • TSH

5-Hydroxyindoleacetic Acid (5-HIAA), 24-Hour Urine, with Creatinine

Patient Preparation: Patient should avoid food high in indoles: avocado, banana, tomato, plum, walnut, pineapple, and eggplant.

Collection Instructions : Collect 24-hour urine with 6N HCL to maintain a pH below 3. Urine without preservative is acceptable if pH is below 6 and the sample is shipped frozen. Keep urine refrigerated during collection if preservative is not used. Shipping refrigerated acceptable, shipping frozen acceptable. Record 24-hour urine volume on test request form and urine vial. Record patient's age on test request form and urine vial.

Clinical Significance: 5-HIAA is the end product of serotonin (5-hydroxytryptophan) and tyrptophan metabolism. Patients with carcinoid tumors of the midgut, e.g., ileum, produce high concentrations of 5-HIAA. Patients with carcinoid tumors of the foregut and hindgut may produce little or no 5-HIAA or do so intermittently.

Limitations: Patients with renal disease may display falsely decreased results. Urinary 5-HIAA is increased in patients with malabsorption disorders who also display a larger concentration of urinary tryptophan metabolites. Urinary 5-HIAA is increased in patients with intestinal obstruction and with some noncarcinoid islet cell tumors. Carcinoid syndrome may not cause elevated results, especially if the patient does not have diarrhea.


Serum albumin measurements are used in the monitoring and treatment of numerous diseases involving those related to nutrition and pathology particularly in the liver and kidney. Serum albumin is valuable when following response to therapy where improvement in the serum albumin level is the best sign of successful medical treatment. There may be a loss of albumin in the gastrointestinal tract, in the urine secondary to renal damage or direct loss of albumin through the skin. More than 50% of patients with gluten enteropathy have depressed albumin. The only cause of increased albumin is dehydration; there is no naturally occurring hyperalbuminemia

Serum alkaline phosphatase levels are of interest in the diagnosis of hepatobiliary disorders and bone disease associated with increased osteoblastic activity. Moderate elevations of alkaline phosphatase may be seen in several conditions that do not involve the liver or bone. Among these are Hodgkin's disease, congestive heart failure, ulcerative colitis, regional enteritis, and intra-abdominal bacterial infections. Elevations are also observed during the third trimester of pregnancy.


Amino acid analysis is necessary for the diagnosis of a variety of inborn errors of metabolism. These include, but are not limited to, phenylketonuria, tyrosimemia, citrullinemia, non-ketotic hyperglycinemia, maple syrup urine disease, and homocystinuria. The assay is also key for the continued monitoring of treatment plans for these disorders and useful for assessing nutritional status of patients. Our methodology is highly accurate at very low levels as well as at elevated levels.

This is a fasting test:  Minimun 4 hours after your last meal, or overnite for most accurate reading.  Non fasting specimens are acceptable for Pediatrics

 


IMPORTANT - The specimen for this test must be collected at a patient service center that can collect, store and transport frozen samples as outlined below.  

IMPORTANT: Before ordering this lab test, check and confirm with the selected patient service center to ensure that they can collect, store and transport frozen samples as outlined below.

Preferred Specimen(s) 

2 mL frozen plasma collected in an EDTA (lavender-top) tube

Collection Instructions 

Collect blood from stasis-free vein of patient (e.g., no tourniquet). Patient should not clench fist during collection, as muscular exertion often increases venous ammonia levels. Patient should avoid smoking prior to phlebotomy since smoking increases plasma ammonia levels. Tubes should be filled completely and kept tightly stoppered at all times. Place immediately on ice. Separate plasma from cells within 20 minutes and freeze plasma immediately.

Transport Temperature 

Frozen

Specimen Stability 

Room temperature: Unstable
Refrigerated: Unstable
Frozen -20° C: 72 hours
Frozen -70° C: 7 days

Reject Criteria 

Hemolysis • Lipemia • Received thawed • PPT Potassium EDTA (white-top) tube

Clinical Significance

Ammonia is one of the by-products of protein metabolism. Elevated blood ammonia levels have been associated with severe liver dysfunction such as hepatic encephalopathy, coma resulting from cirrhosis, severe hepatitis, Reye's syndrome, and drug hepatotoxicity. Also, elevated blood ammonia has been reported in cardiac failure, azotemia, and pulmonary emphysema. Correlation between plasma ammonia and the degree of encephalopathy can be erratic.


Apolipoprotein A1 (APO A1) has been reported to be a better predictor than HDL cholesterol and triglycerides for Coronary Artery Disease (CAD). Low levels of APO A1 in serum are associated with increased risk of CAD. The measurement of APO A1 may be of value in identifying patients with atherosclerosis. Apolipoprotein B (APO B) has been reported to be a more powerful indicator of CAD than total cholesterol or LDL cholesterol in angiographic CAD and in survivors of myocardial infarction. In some patients with CAD, APO B is elevated even in the presence of normal LDL cholesterol.

AST is widely distributed throughout the tissues with significant amounts being in the heart and liver. Lesser amounts are found in skeletal muscles, kidneys, pancreas, spleen, lungs, and brain. Injury to these tissues results in the release of the AST enzyme to general circulation. In myocardial infarction, serum AST may begin to rise within 6-8 hours after onset, peak within two days and return to normal by the fourth or fifth day post infarction. An increase in serum AST is also found with hepatitis, liver necrosis, cirrhosis, and liver metastasis.

See individual tests

Most Popular
Measurement of the levels of bilirubin is used in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gall bladder obstruction. The assessment of direct bilirubin is helpful in the differentiation of hepatic disorders. The increase in total bilirubin associated with obstructive jaundice is primarily due to the direct (conjugated) fraction. Both direct and indirect bilirubin are increased in the serum with hepatitis.

Measurement of the levels of bilirubin is used in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gall bladder obstructive disease

The BUN/Creatinine ratio is useful in the differential diagnosis of acute or chronic renal disease. Reduced renal perfusion, e.g., congestive heart failure, or recent onset of urinary tract obstruction will result in an increase in BUN/Creatinine ratio. Increased urea formation also results in an increase in the ratio, e.g., gastrointestinal bleeding, trauma, etc. When there is decreased formation of urea as seen in liver disease, there is a decrease in the BUN/Creatinine ratio. In most cases of chronic renal disease the ratio remains relatively normal.

C-Reactive Protein Cardiac (hs CRP) Useful in predicting risk for cardiovascular disease.


Most Popular
Serum calcium is involved in the regulation of neuromuscular and enzyme activity, bone metabolism and blood coagulation. Calcium blood levels are controlled by a complex interaction of parathyroid hormone, vitamin D, calcitonin and adrenal cortical steroids. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders and chronic renal disease. A low level of calcium may result in tetany.

Carbamazepine and its metabolite (10, 11-carbamazepine epoxide) are widely used for control of generalized tonic-clonic, partial-onset, complex and mixed seizure disorders. The metabolism of carbamazepine in epileptic patients has several different pathways that can be altered when the patient is co-medicated with other anticonvulsants and, therefore, its therapeutic level should be monitored along with its metabolite in their free and protein bound states.

Carbamazepine and its metabolite (10, 11-carbamazepine epoxide) are widely used for control of generalized tonic-clonic, partial-onset, complex and mixed seizure disorders. The metabolism of carbamazepine in epileptic patients has several different pathways that can be altered when the patient is co-medicated with other anticonvulsants and, therefore, it's therapeutic level should be monitored along with its metabolite in their free and protein bound states.

Carbamazepine and its metabolite (10, 11-Carbamazepine epoxide) are widely used for control of generalized tonic-clonic, partial-onset, complex and mixed seizure disorders. The metabolism of carbamazepine in epileptic patients has several different pathways that can be altered when the patient is co-medicated with other anticonvulsants and, therefore, its therapeutic level should be monitored along with its metabolite in their free and protein bound states

There is a correlation between increased risk of premature heart disease with decreasing size of LDL particles. Ion mobility offers the only direct measurement of lipoprotein particle size and concentration for each lipoprotein from HDL3 to large VLDL.

Serum Triglyceride analysis has proven useful in the diagnosis and treatment of patients with diabetes mellitus, nephrosis, liver obstruction, other diseases involving lipid metabolism, and various endocrine disorders. In conjunction with high density lipoprotein and total serum cholesterol, a triglyceride determination provides valuable information for the assessment of coronary heart disease risk.

Measurement of serum 25-OH vitamin D concentrations provide a good index of circulating vitamin D activity in patients not suffering from renal disease. Lower than normal 25-OH vitamin D levels can result from a dietary deficiency, poor abosrption of the vitamin or impaired metabolism of the sterol in the liver. A 25-OH vitamin D deficiency can lead to bone diseases such as rickets and osteomalacia. Above normal levels can lead hypercalcemia. This assay employs liquid chromatography tandem mass spectrometry to independently measure and report the two common forms of 25-hydroxy vitamin D: 25OH D3 - the endogenous form of the vitamin and 25OH D2 - the analog form used to treat 25OH Vitamin D3 deficiency.

Approximately 1 in every 2500 individuals has inherited a defective enzyme or a deficiency of the enzyme (Pseudocholinesterase) that metabolizes succinylcholine (an anesthetic agent). With a "normal" dosage, these individuals have prolonged apnea. Such individuals are responsive at much smaller concentrations of this anesthetic agent than the general population. Low concentrations of Pseudocholinesterase are observed in individuals exposed to organophosphorous insecticides and in patients with hepatic dysfunction.

A Complete Blood Count (CBC) Panel is used as a screening test for various disease states including anemia, leukemia and inflammatory processes.

A CBC blood test includes the following biomarkers: WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet count, Neutrophils, Lymphs, Monocytes, Eos, Basos, Neutrophils (Absolute), Lymphs (Absolute), Monocytes(Absolute), Eos (Absolute), Basos (Absolute), Immature Granulocytes, Immature Grans (Abs)

NOTE: Only measurable biomarkers will be reported.


See individual tests


The Differences Between Fast Metabolism and Slow Metabolism Tests

If you've got a metabolism that you just can't figure out, we understand. Everyone's metabolism is different. Plus, your metabolism can change over time and often does. You've probably noticed that you gain weight easier now that you're older than you did when you were in your teens, and this is completely normal. In fact, this is typical for many people. However, if you're a younger person and gain weight easily, there's no need to fret, as that's also common.

You've probably heard that people with a fast metabolism can eat anything and get away with it -- but why is this? How does a person's metabolism work? What is metabolism testing? We know you probably have a lot of questions, so without any further ado let's dive in. 

Fast Metabolism Vs. Slow Metabolism

Metabolism is a term that's thrown around quite a bit, but for all intents and purposes, it describes the internal process of how your body uses energy and gets rid of calories. This includes blood circulating through the body, breathing, and your organs functioning. A person with a fast metabolism might have a body with more muscle mass that uses more energy to perform everyday tasks than someone with a slow metabolism, meaning they need to consume more calories to keep everything stable. Think of a fast metabolism as a gas-guzzling pickup truck and a slow metabolism as a fuel-efficient smart car -- the pickup truck needs more fuel to function!

Someone with a fast metabolism burns calories faster naturally, while someone with a slow metabolism burns them more slowly. However, most people have average metabolisms, meaning they align with the 2,000 calorie diet which is recommended for most people. 

What this means is two people with different metabolisms who eat the same amount of food will absorb calories differently. A young, busy athlete might need to eat twice as much as someone ten years older who lives a sedentary lifestyle to maintain the same amount of weight as them. However, age plays a key role in how your metabolism functions. Typically speaking, the older you get, the more your metabolism slows down. 

What Determines the Kind of Metabolism You Have? 

This news might be disappointing, but your metabolism is mostly influenced by genetics. Since you can't do much to change your DNA, there's no real way to alter how your metabolism functions. However, diet and exercise play huge roles in how your body absorbs nutrients and converts food into energy, so knowing what kind of metabolism you have can make it much easier to achieve your ideal weight or maintain a healthy lifestyle -- regardless of the metabolism you were born with. 

How Can You Find Out What Kind of Metabolism You Have?

If you find yourself full after smaller meals or don't seem to need to eat that much to live a normal life, then you might have a slow metabolism. The same is true if you don't feel like you eat that much but still struggle with weight gain or find it difficult to lose weight. However, it would be best to consider how much exercise you get and examine the amount of calories you're taking in on average. You might not need that much fuel because you don't use that much energy on a regular basis. However, if you're constantly hungry and can snack all day and never seem to gain any weight, then you probably have a faster metabolism. 

Metabolism tests are, without a doubt, the easiest way to know for sure what kind of metabolism you're working with. While it's fairly obvious for most people, sometimes other factors get in the way and make it difficult to know for sure. Factors that can affect how your metabolism functions include the kind of food you're eating, the amount of activity you perform every day, and any illnesses or medical conditions you might have. Metabolism tests can set your mind at ease and confirm whether you have a fast metabolism or a slow one. 

What Kinds of Metabolic Testing Is There? 

Lab Tests

While home tests might seem to be a convenient option when it comes to conducting any sort of test, this isn't really the case. They come with a list of problems. First and foremost, they are not entirely reliable. The samples are not collected by trained technicians in an appropriate environment. It's very easy for at-home tests to show incorrect results. Second, those tests are not generally accepted by doctors and hospitals. If you were to show those results to your doctor, they would most likely recommend that you repeat the testing with a blood draw at a national lab. Third, only a limited number of tests are available that restrict the insight into your health.

Our comprehensive metabolic testing solution does not suffer from any of these problems. All of our tests are considered highly accurate and reliable. They are also accepted by all doctors and health organizations, unlike at-home tests. Why? Because the samples are gathered and tested in the same way as doctors expect them to be. All samples are handled by certified professionals in a certified institution. All of those certifications help guarantee quality and accuracy.

Metabolic Discovery Panel - It contains 8 tests with 68 biomarkers. This comprehensive set of tests helps assess your metabolism. Are you storing too much fat and sugar or perhaps too little? Are you insulin resistant with subsequent inflammation? You can run this panel to discover whether your diet, fitness, and nutritional habits are providing you the metabolic health and longevity you deserve. Don't settle for one-size-fits-all health advice. Your diet, fitness lifestyle, and nutritional intake should improve your energy, weight, and inner metabolic health. But don't merely trust it's working. Run this Metabolic Discovery panel quarterly to take a snapshot of your insulin response, blood sugars, and lipids and adjust your lifestyle based upon your results.

  • CBC (includes Differential and Platelets)
  • Comprehensive Metabolic Panel (CMP) includes fasting Glucose
  • Ferritin
  • Hemoglobin A1c
  • Insulin
  • Lipid Panel with Ratios
  • Vitamin B12 (Cobalamin)
  • Vitamin D, 25-Hydroxy, Total, Immunoassay

The Metabolic Discovery Comprehensive Panel - It contains 15 tests with 78 biomarkers and all of the tests in the Metabolic Discovery Panel, plus:

  • Adiponectin
  • Iron and Total Iron Binding Capacity (TIBC)
  • Leptin
  • T3, Free
  • T4, Free
  • TSH

Metabolism Lab Panel - it contains 6 tests with 27 biomarkers.

  • Fasting Insulin
  • Glucose (In CMP)
  • Hemoglobin A1c
  • TSH
  • Free T3
  • Free T4
  • Comprehensive Metabolic Panel (CMP)

RMR Testing

There are various methods used to test what kind of metabolism a person has. These include determining a person's resting metabolic rate, or RMR. This refers to how many calories your body burns while at rest. Someone with a faster metabolism will burn more calories while doing nothing at all. 

VO2 Max Testing

Another kind of metabolic testing measures your maximum volume of oxygen, or VO2 Max, which refers to how your body utilizes oxygen while exercising. An athletic person will have a higher VO2 max and therefore have a higher capacity for high-intensity exercise, while someone who doesn't exercise all that much won't use oxygen as effectively. 

Lactate Threshold Testing

When your muscles become fatigued, this is due to a buildup of lactic acid, which your body makes when it can't use oxygen to produce energy. Usually, a buildup occurs during exercise. While your body naturally eliminates lactic acid, when exercising you will eventually reach a point where your body is making too much to be eliminated, causing you to become tired and your muscles to feel strained, stiff, and tired. Your lactate threshold refers to when your body is producing lactic acid in the blood faster than it can eliminate it. 

How Do I Test My Metabolism? 

Ulta Lab Tests offers highly accurate and reliable tests so you can make informed decisions about your health.

  • Secure and confidential results
  • No insurance referral is needed
  • Affordable pricing
  • 100% satisfaction guarantee

Order your metabolism lab tests today, and your results will be provided to you securely and confidentially online in 24 to 48 hours for most tests.

Take control of your health today with Ulta Lab Tests.