Cardio IQ Tests

Do you know how healthy your cardiovascular system is?

Cardio IQ blood tests are the best way to measure your risk of heart attack and stroke and keep track of your cardiovascular health.

The Cardio IQ lab tests can help you determine how well your heart and blood vessels are doing. Cardio IQ lab tests are a collection of necessary blood tests that can help you assess your cardiovascular health. It's a simple way to keep track of your heart health and avoid serious problems. These comprehensive lab panels can tell you if you're at risk for coronary artery disease, stroke, or other life-threatening illnesses. These are necessary tests to take if you have risk factors for coronary artery disease (CAD), such as high cholesterol or high blood pressure.

If you have diabetes, smoke cigarettes, are overweight or obese or have a family history of early heart disease, you may be at risk for CAD. Plaque builds up inside the arteries that deliver oxygen-rich blood to the heart muscle, causing this disease. This deposit damages the arteries over time, making them less flexible and preventing them from expanding adequately during physical activity such as exercise or sex. The normal flow of oxygen-rich blood into the heart muscle is restricted when this happens, resulting in angina pectoris (chest discomfort) and chronic stable angina pectoris (shortness of breath with physical effort). In certain situations, it can result in a life-threatening event known as myocardial infarction, also known as a "heart attack," in which one or more coronary arteries become blocked by clots accumulating on top of atherosclerotic plaques in these vessels, leading to loss of function and death.

Get the Cardio IQ lab tests that your doctor recommends to find out if you're at risk for a heart attack or a cardiovascular event such as a stroke. Choose from the tests below and place an order with Ulta Lab Tests today for affordable, accurate, quick blood work and confidential testing.

For additional information on Cardio IQ Lab Testing, Click here.

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Measuring Lipid Subclasses using Ion Mobility

The way most doctors test for heart disease is with a lipid panel. It helps detect what HDL (good) and LDL (bad) cholesterol are, so hopefully you can reduce your risk of a possible cardiac event such as a heart attack. Nearly half of all heart attack patients were found to have no prior risk which would indicate they were heading toward an attack.

Quest Diagnostics offers advanced cardiovascular tests that help provide a more accurate and individualized picture of risk. The tests look beyond just HDL and LDL cholesterol to identify undiagnosed (or additional) risk.

These advanced cardiovascular tests, along with your lipid panel, will provide more information that you and your doctor can use to understand your complete cardiovascular health.

Lipid Subclasses as measured by Ion Mobility Technology

Knowing what particles make up your LDL and HDL cholesterol may be important. Ion Mobility Technology provides subclass separation that will allow your healthcare provider to identify your cardiovascular risk over time. Following the change in your lipid profile as you respond to diet, exercise and possible medication to reduce your cardiovascular risk is important. Ion Mobility provides the opportunity to determine if treatment is working and if not, optimize the aggressiveness of therapy to hopefully make a difference that can be seen in the Ion Mobility measurement and graphical representation of your LDL and HDL particles. 

Cardio IQ™ Lipoprotein Fractionation, Ion Mobility 
Cardio IQ™ Lipid Panel
Cardio IQ™ Direct LDL 
Cardio IQ™ Apolipoprotein Evaluation 
Cardio IQ™ Lipoprotein (A)

Apo B

  • Apo B is a direct measurement of the number of lipoprotein particles, including LDL (“bad cholesterol”), IDL, and VLDL
  • A high Apo B number indicates increased risk for heart disease
  • Certain medications, improved eating habits, increased physical activity, and loss of body fat are some ways to
    improve Apo B

Lipoprotein (A) - Lp(a)

  • High levels of Lp(a) are associated with increased risk of cardiovascular disease and stroke
  • Lp(a) levels may be influenced by genetics. Diet and exercise have limited to no effect on lowering Lp(a); however, certain
    medications can lower levels


  • Apolipoprotein A1 is the primary protein associated with HDL cholesterol. Like HDL cholesterol, increased concentrations are associated with reduced risk of cardiovascular disease. Apolipoprotein B-100 is the primary protein associated with LDL cholesterol and other lipid particles. Like LDL cholesterol, increased concentrations are associated with increased risk of cardiovascular disease. The ratio of these two apolipoproteins correlates with risk of cardiovascular disease.

Cardio IQ® ASCVD Risk Panel with Score 

This panel provides the 10-year and lifetime risk of atherosclerotic cardiovascular disease (ASCVD) using lipid results with anthropomorphic data and family history. 
The ASCVD risk assessment is recommended in the 2013 ACC/AHA Guidelines on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults.

IMPORTANT: For risk calculations to be performed, the following patient-specific information must be provided and recorded at the time of specimen collection:

  • Age: Years 
  • Gender: M (for male) or F (for female) 
  • Height Feet: Feet 
  • Height Inches: Inches 
  • Weight: lbs 
  • Race-African American: Y (for yes) or N (for no) 
  • Systolic Blood Pressure: mmHg
  • Diastolic Blood Pressure: mmHg
  • Treatment for High B.P.: Y (for yes) or N (for no) 
  • Diabetes Status: Y (for yes) or N (for no)
  • Parental History of Diab: Y (for yes) or N (for no) 
  • Smoking Status: Y (for Yes) or N (for no)



Cardio IQ® Insulin Resistance Panel with Score


  • Insulin, Intact, LC/MS/MS
  • C-Peptide, LC/MS/MS
  • Insulin Resistance Score

Patient Preparation

  • Overnight fasting is required

Clinical Significance

The determination of insulin in serum is primarily used for the diagnosis of glycemic disorders in diabetic and pre-diabetic patients in the assessment of insulin resistant syndromes. Insulin is synthesized by the pancreatic beta cell as a precursor, proinsulin. Proinsulin is processed to insulin and C-peptide, a contiguous peptide between the insulin A and B chains, as it passes through the cell. The C-peptide in the proinsulin ensures correct folding and processing of proinsulin as it passes through the cell. Both insulin and C-peptide are released together from the beta cells in response to increased glucose levels. Because of differences in half-life and hepatic clearance, peripheral blood levels of C-peptide and insulin are no longer equimolar but remain highly correlated. A steady-state plasma glucose test in individuals undergoing an insulin suppression test to assess insulin resistance found that the combination of insulin and C-peptide was a better indicator of insulin resistance than either one individually.



Cardio IQ® Myeloperoxidase (MPO)

Clinical Significance

Myeloperoxidase testing may be used for individuals with multiple risk factors for cardiovascular disease, or those with established disease.

The test was developed and its performance characteristics determined by Cleveland HeartLab, Inc. 

Performing Laboratory 

Cleveland HeartLab, Inc 

6701 Carnegie Avenue, Suite 500

Cleveland, OH 44103-4623


This test will aid physicians in the assessment of risk of atrial fibrilation and cardioembolic stroke.

This test will aid in the assessment of risk associated with myocardial infarction (MI), especially before age 50 in males and age 60 in females.

This test determines the subtypes of apoe which will aid in the risk assessment of corornary heart disease (CHD) and hyperlipoproteinemia.

Apolipoprotein A1 is the primary protein associated with HDL cholesterol. Like HDL cholesterol, increased concentrations are associated with reduced risk of cardiovascular disease.

There are two major forms of Apolipoprotein B, B-100 and B-48. B-100, synthesized in the liver, is the major protein in VLDL, IDL, and LDL cholesterol. B-48, synthesized in the intestines, is essential for the assembly and secretion of chylomicrons. Patients with increased concentrations of Apolipoprotein B are at increased risk of atherosclerosis.

Apolipoprotein A1 is the primary protein associated with HDL cholesterol. Like HDL cholesterol, increased concentrations are associated with reduced risk of cardiovascular disease. Apolipoprotein B-100 is the primary protein associated with LDL cholesterol and other lipid particles. Like LDL cholesterol, increased concentrations are associated with increased risk of cardiovascular disease. The ratio of these two apolipoproteins correlates with risk of cardiovascular disease.

Total serum cholesterol analysis is useful in the diagnosis of hyperlipoproteinemia, atherosclerosis, hepatic and thyroid diseases.

This test detects variants in the CYP2C19 gene leading to altered enzyme activity and may require alternative treatments or altered drug dosage of a drug metabolized by CYP2C19 for optimal therapeutic response.

LDL Cholesterol is referred to as the "bad" cholesterol. Interpretive ranges are based on the guidelines of the National Cholesterol Education Program (NCEP).

Low levels of fibrinogen are associated with bleeding most commonly secondary to liver disease or disseminated intravascular coagulation (DIC). Fibrinogen is an acute phase reactant and thus elevated levels may be associated with inflammation. Increased concentrations are also associated with increased risk of atherosclerosis.

HDL Cholesterol is inversely related to the risk for cardiovascular disease. It increases following regular exercise, moderate alcohol consumption and with oral estrogen therapy. Decreased levels are associated with obesity, stress, cigarette smoking and diabetes mellitus.

To assist with control of blood glucose levels, the American Diabetes Association (ADA) has recommended glycated hemoglobin testing (HbA1c) twice a year for patients with stable glycemia, and quarterly for patients with poor glucose control. Interpretive ranges are based on ADA guidelines

An elevated concentration of Homocysteine is an independent risk factor for cardiovascular disease.

Useful in predicting risk of cardiovascular disease.

Insulin is useful in diagnosing hyperinsulinemia in hypoglycemic patients. Hyperinsulinemia may be due to an insulin-producing tumor (insulinoma), syndrome of insulin resistance, or persistent hyperinsulinemic hypoglycemia of infancy.

This test detects a gene variant associated with increased coronary heart disease (CHD) risk and such CHD event can be reduced from atorvastatin and pravastatin therapy.

This is the most common Lipid Panel. Components include those useful in the detection, classification, and monitoring of patients with hyperlipidemia.

Elevated concentrations of Lp(a) are associated with increased risk of coronary artery disease.

There is a correlation between increased risk of premature heart disease with decreasing size of LDL particles. Ion mobility offers the only direct measurement of lipoprotein particle size and concentration for each lipoprotein from HDL3 to large VLDL.

Cardio IQ Lp-PLA2 Activity

Clinical Significance

Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet activating factor Acetylhydrolase, is an inflammatory enzyme that circulates bound mainly to low density lipoproteins and has been found to be localized and enriched in atherosclerotic plaques. In multiple clinical trials, Lp-PLA2 activity has been shown to be an independent predictor of coronary heart disease and stroke in the general population. Measurement of Lp-PLA2 may be used along with traditional cardiovascular risk factor measures for identifying individuals at higher risk of cardiovascular disease events. Clinical management may include beginning or intensifying risk reduction strategies. The activity assay is an enzyme assay run on an automated chemistry platform.

This test identifies individuals who are at risk of having elevated plasma lipoprotein (a) [Lp (a)] and increased cardiovascular risk which could be reduced by low-dose aspirin therapy.

Did you know that almost half of all American adults have some form of cardiovascular ailment?

report was published in 2019 by the Journal of the American Heart Association.

In the 2019 report, it was revealed that 121.1 million adults in America (48% of the 2019 numbers) have cardiovascular ailments.

With this being the case, it makes sense to take the necessary precautions to protect your health.

And one of the best ways to do that is by having your blood tested with cardio IQ testing.

If you're interested in learning more about cardio IQ lab tests to evaluate the health of your cardiovascular system, keep reading.

We will provide you with an overview of the available tests to help you know about your heart and provide insights into your health.

What Is Cardio IQ Testing?

Cardio IQ testing is essentially a testing procedure used to assess the LDL particles in your body to measure the likelihood of heart disease. Clinicians then use this detailed data to create a more efficient and customized treatment for patients.

Furthermore, this type of blood test makes diagnostics much more accurate and precise than they would have been otherwise.

Think of this kind of testing as an overview -- the big picture, if you will -- of the condition of your overall cardiovascular health and wellbeing.

It can both save and extend your life by finding indicators of certain ailments (heart disease, high blood pressure, high cholesterol, etc.).

The Benefits of Cardio IQ Testing Lab Testing

A cardio IQ advanced lipid panel test can provide many advantages. You could benefit from one immensely as it offers a more detailed analysis of your working cardiovascular system.

This will give way to greater protection against any potential cardiovascular diseases (CVD) that you may currently be unaware of. 

The importance of this cannot be understated. Every year, heart disease takes the lives of about 8 times the number of women who have breast cancer and 15 times the number of men who have prostate cancer.

In addition to that, a new study uncovered an interesting finding.

Almost 75% of people who were emitted to the hospital following a heart attack displayed no signs of being at risk for one.

Blood tests can help with avoiding such events from happening before it's too late. Then adjustments to lifestyle can be made preemptively to prevent such occurrences from taking place.

But that's not all a cardio IQ test can help you prevent. Here are a few more examples of avoidances to keep in mind:

  • High blood pressure
  • Metabolic syndrome
  • Cardiometabolic risk
  • Low HDL (high-density lipoproteins)
  • High triglycerides
  • Diabetes

It's suggested that you should try fasting for 9 to 12 hours before having your blood drawn.

The cardio IQ test record will reveal a detailed assessment of any cardiovascular dangers. This is what will enable physicians to do a better job with their diagnostics.

Physicians can be more accurate with their suggestions. And as a result, prescribe the perfect treatments and proper resources to help you reduce any budding cardiovascular ailments.

Cardio IQ Tests

There are a group of important Cardio IQ blood tests to select from -- each with its specific value to identify the health of your cardiovascular system.

Here is a list of the Cardio IQ tests you should consider:

Cardio IQ Lipid Panel

This is undoubtedly the most common and repeated Lipid Panel. Elements include the factors useful in the detection of patients who have hyperlipidemia.

Cardio IQ Lipoprotein (A)

Higher amounts of LPA are connected with the enhanced danger of coronary heart disease.

Cardio IQ Lipoprotein Fractionation, Ion Mobility

There seems to be a strong connection between a heightened danger of untimely heart disease with a reduced amount of low-density lipoprotein particles. Ion Mobility provides a direct assessment of LDL particle size.

Cardio IQ Apolipoprotein A-1

Apolipoprotein A1 is the main protein connected with high-density lipoproteins (HDL). Similar to HDL cholesterol, enhanced concentrations are connected with lower dangers of cardiovascular ailments.

Cardio IQ Apolipoprotein B

As it pertains to Apolipoprotein B, two main forms can be found, B-48 and B-100. B-100, arranged and manufactured in the liver, is the main protein of very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), as well as low-density lipoprotein cholesterol.

Cardio IQ Apolipoprotein Evaluation

The primary protein that is associated with HDL cholesterol is Apolipoprotein A1. The dominant protein connected with lipid particles as well as HDL cholesterol is Apolipoprotein B-100.

The percentages of the two apolipoproteins connect with the danger of cardiovascular ailments.

Cardio IQ Cholesterol, Total

Total serum cholesterol examination is handy in the prognosis of hyperlipoproteinemia, thyroid ailments, etc.

Cardio IQ Direct LDL

Low-density lipoprotein cholesterol is known as "bad" cholesterol. Different ranges of its risk are based on the guidelines that are supplied by the NCEP (National Cholesterol Education Program).

Cardio IQ Fibrinogen Antigen, Nephelometry

Lower amounts of fibrinogen are associated with bleeding, commonly second to liver disease or DIC (Disseminated Intravascular Coagulation).

Cardio IQ HDL Cholesterol

High-density lipoprotein cholesterol ("good cholesterol") correlates to the danger of cardiovascular diseases. It elevates with regular exercise, medium alcohol intake, and with oral estrogen treatment.

Lowered levels occur with obesity, distress, as well as the smoking of cigarettes and diabetes.

Cardio IQ Hemoglobin A1c

To help with blood glucose regulation, the ADA (American Diabetes Association) has suggested hemoglobin A1c testing (HbA1c) two times annually for those who suffer from glycemia and then quarterly for those with bad glucose levels.

Cardio IQ Homocysteine

higher amount of homocysteine is an unhampered factor in cardiovascular ailments.

Cardio IQ hs-CRP

The Cardio IQ hs-CRP test is very accurate in foreseeing the risks and potential of cardiovascular ailments.

Cardio IQ Insulin

This insulin test is used to identify hyperinsulinemia in individuals. The effects of hyperinsulinemia might be due to a tumor producing insulin (insulinoma), a syndrome caused by insulin resistance.

Cardio IQ CYP2C19 Genotype

Genotype tests can discover different variations in the CYP2C19 gene in the segment of DNA, leading to changed enzyme acts. Additionally, it may need other treatments or an amount of medication to achieve therapeutic levels.

Cardio IQ 4q25-AF Risk Genotype

This is a test that will assist physicians in measuring the risk for AFib (atrial fibrillation) and stroke. As many as 8 cardiovascular-connected genetic tests can be done on a single person.

Cardio IQ 9p21 Genotype

This is a test that will help measure risk connected with MI (Myocardial Infarction). It will be especially effective in males below the age of 50 and females below the age of 60.

Cardio IQ ApoE Genotype

This test is used to determine isotypes of ApoE, which will assist with the measurement of CHD (Coronary Herat Disease) as well as hyperlipoproteinemia.

Cardio IQ KIF6 Genotype

This is a test that will find and uncover variants of genes connected with an enhanced danger of CHD (Coronary Heart Disease).

Frequently Asked Questions About Cardio IQ Testing

When it comes to a complex subject such as cardio IQ testing, no matter how much we cover, there will be questions left unanswered. So here are a few frequently asked questions that you may have:

What Exactly Is a Cardio Test Panel?

The test panel is important because it works to assess a multitude of markers as well as lipid subfractions. This can be helpful for finding ailments sooner and more efficiently.

It helps to provide a broader and more complete assessment of dyslipidemia as well as a cardiovascular risk than the traditional lipid panel provides.

Why Is the Test Panel so Important?

The test panel assesses the quality level of a person's lipid markers as well as apolipoprotein B, in addition to the lipoprotein particle numbers and sizes.

This then makes it much easier to provide a more detailed measurement of the general cardiac risk.

Does It Take a Long Time to Receive the Results?

It can take around 1 to 2 business days to receive the results of Cardio IQ tests.

Benefits of CARDIO IQ Lab Testing With Ulta Lab Tests

Ulta Lab Tests offers highly accurate and reliable tests so that you can make informed decisions about your health. Here are a few great things to love about Ulta Lab Tests:

  • You'll get secure and confidential results.
  • You don't need health insurance.
  • You don't need a physician's referral
  • You'll get affordable pricing
  • We offer a 100% satisfaction guarantee

Are You Ready for Your Cardio IQ Test?

Order your Cardio IQ lab test today, and your results will be provided to you securely and confidentially online