Pituitary Disorders

The pituitary gland coordinates many body systems by signaling the thyroid, adrenals, ovaries/testes, and growth pathways. When pituitary hormones are too high or too low, you may notice headaches, vision changes, menstrual or sexual changes, growth or body-composition shifts, fatigue, or thirst and urination changes.

Pituitary testing starts with targeted blood and urine tests that check the major axes: prolactinIGF-1 (growth hormone action)ACTH/cortisolTSH/free T4, and LH/FSH with testosterone or estradiol. For water-balance symptoms, serum sodium and&n... See more

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The Cortisol Test with 2 specimens measures adrenal gland function by evaluating cortisol levels at two collection times. Tracking changes in this stress hormone helps assess adrenal performance, circadian rhythm, and the body’s stress response, while offering insight into conditions such as adrenal insufficiency, Cushing’s syndrome, Addison’s disease, and overall endocrine balance.

Blood
Blood Draw
Also Known As: 2 Specimen Cortisol Blood Test

The Cortisol Test with 3 specimens measures adrenal gland function by evaluating cortisol levels at three collection times. Monitoring this stress hormone helps assess circadian rhythm, adrenal performance, and daily hormone balance, while providing insight into adrenal insufficiency, Addison’s disease, Cushing’s syndrome, and overall endocrine and metabolic health.

Blood
Blood Draw
Also Known As: 3 Specimen Cortisol Blood Test

The Cortisol Test with 5 specimens measures adrenal gland function by evaluating cortisol levels at five collection times. Monitoring this stress hormone throughout the day provides insight into circadian rhythm, adrenal performance, and hormone balance, while helping detect adrenal insufficiency, Addison’s disease, Cushing’s syndrome, stress dysregulation, and overall endocrine health.

Blood
Blood Draw
Also Known As: 5 Specimen Cortisol Blood Test

The Cortisol Test with 6 specimens measures adrenal gland function by evaluating cortisol levels at six collection times. Monitoring this stress hormone across the day provides insight into circadian rhythm, adrenal performance, and hormone balance, while supporting detection of adrenal insufficiency, Addison’s disease, Cushing’s syndrome, stress dysregulation, and overall endocrine health.

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Blood Draw
Also Known As: Cortisol Total Test, Cortisol 6 Specimen Test, 6 Specimen Cortisol Test, Cortisol Blood Test, Cortisol Serum Test

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The Cortisol AM Test measures morning cortisol levels in blood to evaluate adrenal gland function and stress response. Cortisol peaks in the morning, making this test critical for detecting adrenal insufficiency (Addison’s disease), Cushing’s syndrome, or other hormone imbalances. Doctors also use it to investigate fatigue, weight changes, or high blood pressure. This test provides important insight into endocrine health, metabolism, and long-term stress regulation.

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Blood Draw
Also Known As: Morning Cortisol Test

The Cortisol Free 24-Hour Urine with Creatinine Test measures cortisol excreted in urine over 24 hours, with creatinine used to validate collection. Elevated cortisol may indicate Cushing’s syndrome, while low levels can suggest Addison’s disease or adrenal insufficiency. Doctors order this test for patients with obesity, fatigue, high blood pressure, or abnormal hormone symptoms. Results provide critical insight into adrenal gland function and hormone regulation.

Urine
Urine Collection
Also Known As: Unbound Urine Cortisol Test

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The Cortisol PM Test measures afternoon cortisol levels to evaluate adrenal and pituitary function. Cortisol normally drops later in the day, so abnormal results may indicate Cushing’s syndrome, adrenal insufficiency (Addison’s disease), or hormone imbalance. Doctors order this test to investigate fatigue, obesity, high blood pressure, or irregular sleep patterns and to monitor adrenal disorders. It provides key insight into stress response and endocrine health.

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Blood Draw
Also Known As: Afternoon Cortisol Test

The Cortisol Total Test measures cortisol levels in blood to assess adrenal gland and pituitary function. Cortisol regulates stress response, metabolism, and immune health. Abnormal results may indicate Cushing’s syndrome, Addison’s disease, or other hormone disorders. Doctors order this test to evaluate symptoms like fatigue, weight changes, weakness, or high blood pressure and to monitor treatment. It provides essential insight into hormone balance and endocrine health.

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Blood Draw
Also Known As: Cortisol Blood Test

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The Estradiol (E2) Test measures levels of estradiol, the primary form of estrogen, to evaluate reproductive and hormonal health. It helps assess menstrual irregularities, fertility issues, menopause status, and estrogen-producing disorders. In men, it aids in diagnosing hormonal imbalances. Doctors use the estradiol test to monitor hormone therapy, ovarian function, and conditions affecting puberty, bone health, and overall endocrine balance.

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Blood Draw
Also Known As: E2 Test, Estrogen 2 Test

The Estradiol Free Test measures unbound estradiol, the biologically active form of estrogen, to evaluate hormonal balance. Free estradiol plays a critical role in reproductive health, menstrual regulation, bone strength, and cardiovascular function. Abnormal levels may indicate conditions such as infertility, polycystic ovary syndrome, menopausal transition, or estrogen-related endocrine disorders, aiding diagnostic and treatment decisions.

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Blood Draw

The Estradiol Ultrasensitive Test measures very low levels of estradiol (E2), the primary form of estrogen, to evaluate reproductive and endocrine health. It is especially useful for men, children, postmenopausal women, and patients on hormone therapy. Doctors use this test to assess fertility issues, menstrual irregularities, delayed or early puberty, and monitor treatment for hormone-sensitive cancers or endocrine disorders.

Also Known As: Ultrasensitive E2 Test, Ultrasensitive Estrogen 2 Test

The Estradiol and Estrone Test measures two primary forms of estrogen to assess hormonal balance, ovarian function, and endocrine health. Estradiol, the most active estrogen, and estrone, the predominant form after menopause, provide insight into reproductive health, fertility, and menopausal transition. This test aids in evaluating estrogen-related disorders, hormone therapy monitoring, and overall endocrine function.


The Estrogen Total Test measures all forms of estrogen in blood, including estradiol, estrone, and estriol, to assess reproductive and hormonal health. Abnormal levels may indicate menstrual irregularities, menopause status, infertility, or hormone-related disorders. Doctors order this test to evaluate fertility, monitor hormone therapy, and investigate symptoms such as hot flashes, irregular cycles, or abnormal bleeding. It provides key insight into endocrine and reproductive function.

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Blood Draw
Also Known As: Total Estrogen Test, Estrogen Serum Test

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The Follicle-Stimulating Hormone (FSH) Test measures FSH levels to evaluate reproductive and endocrine health in both men and women. In women, it helps assess infertility, irregular periods, menopause, or ovarian function. In men, it is used to check sperm production and testicular function. Abnormal results may indicate PCOS, pituitary disorders, or hormonal imbalance. Doctors order this test to guide fertility treatment, hormone therapy, and overall reproductive care.

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Blood Draw
Also Known As: Follicle Stimulating Hormone Test, Follitropin Test

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The FSH and LH Test measures follicle-stimulating hormone (FSH) and luteinizing hormone (LH) to evaluate reproductive and endocrine health in both men and women. In women, it helps assess menstrual irregularities, infertility, menopause, or polycystic ovary syndrome (PCOS). In men, it aids in diagnosing low testosterone, infertility, or testicular dysfunction. Doctors also use this test to investigate puberty disorders, hormone imbalance, and pituitary function.

Also Known As: Follitropin Test, Lutropin Test, Interstitial Cell Stimulating Hormone Test, ICSH Test

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The Glucose Test measures blood sugar levels to evaluate energy metabolism and screen for diabetes or prediabetes. Abnormal glucose may indicate hyperglycemia, hypoglycemia, or metabolic disorders. Doctors use this test during routine exams, to investigate symptoms like fatigue, excessive thirst, or frequent urination, and to monitor treatment for diabetes. It provides essential insight into how the body regulates blood sugar and overall metabolic health.

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Blood Draw
Also Known As: Fasting Glucose Test, Fasting Blood Sugar Test

The Glucose Tolerance Test, 2 Specimens, 75g evaluates the body’s glucose metabolism by testing fasting and one-hour blood glucose levels after ingestion of a 75-gram glucose solution. It is an important diagnostic tool for identifying impaired glucose regulation, prediabetes, and type 2 diabetes. This test helps reveal early changes in insulin sensitivity and overall metabolic function.

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Blood Draw
Also Known As: Glucose 2 Specimen Test, Glucose 2 Hour Test, 2 Specimen Glucose Test

The Glucose Tolerance Test, 3 Specimens, 75g evaluates blood sugar at fasting, 1-hour, and 2-hour intervals following a 75-gram glucose drink. It is a key diagnostic tool for identifying impaired glucose regulation, prediabetes, and type 2 diabetes. Measuring glucose response at multiple times allows clinicians to assess insulin function, detect early metabolic dysfunction, and better understand progression to diabetes.

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Blood Draw
Also Known As: Glucose 3 Specimen Test, Glucose 2 Hour Test, Glucose 1 hour Test, 3 Specimen Glucose Test

The Glucose Tolerance Test, 4 Specimens evaluates blood glucose at fasting, 1-hour, 2-hour, and 3-hour intervals after a glucose drink. This test is an important tool for diagnosing or screening for prediabetes, type 2 diabetes, and impaired glucose metabolism. Measuring glucose response across multiple specimens provides valuable data on insulin function, carbohydrate handling, and overall metabolic health.

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Blood Draw
Also Known As: Glucose 4 Specimen Test, Glucose 3 Hour Test, Glucose 1 and a Half Hour Test, 4 Specimen Glucose Test

The Glucose Tolerance Test, 5 Specimens evaluates glucose response at fasting, 1, 2, 3, and 4 hours after a standard glucose drink. By analyzing multiple specimens, it identifies impaired glucose tolerance, prediabetes, and type 2 diabetes. The test provides clinicians with extensive information on insulin function, glucose regulation, and the progression of metabolic disorders that affect long-term health outcomes.

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Blood Draw
Also Known As: Glucose 5 Specimen Test, Glucose 4 Hour Test, Glucose 2 hour Test, 5 Specimen Glucose Test

The Glucose Tolerance Test, 6 Specimens evaluates blood sugar response at fasting and hourly intervals up to 5 hours after ingestion of a glucose solution. This test provides a comprehensive assessment of glucose metabolism, helping detect impaired glucose tolerance, prediabetes, and diabetes risk. Measuring six specimens reveals detailed patterns of insulin function, metabolic regulation, and progression to chronic disease.

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Blood Draw
Also Known As: Glucose 6 Specimen Test, Glucose 5 Hour Test, Glucose 2 and half hour Test, 6 Specimen Glucose Test

The Glucose Tolerance Test, 7 Specimens evaluates blood sugar at fasting and six hourly intervals after ingestion of a glucose solution, spanning 6 hours of monitoring. It is used to identify prediabetes, diabetes, and impaired glucose regulation. By analyzing seven specimens, the test reveals patterns in insulin function, metabolic regulation, and progression of abnormalities that impact long-term health.

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Blood Draw
Also Known As: Glucose 7 Specimen Test, Glucose 6 Hour Test, Glucose 3 Hour Test, 7 Specimen Glucose Test

The Growth Hormone Test measures GH levels in blood to evaluate pituitary gland function, growth disorders, and metabolic health. Abnormal levels may indicate acromegaly, gigantism, or growth hormone deficiency. Doctors use this test to assess children with short stature, adults with suspected hormone imbalance, or patients with pituitary tumors. Results provide critical insight into endocrine function, metabolism, and overall growth regulation.

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Blood Draw
Also Known As: GH Test, HGH Test, Human Growth Hormone Test, Somatotropin Test

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The IGF-1 Test measures insulin-like growth factor 1, a hormone regulated by growth hormone (GH), to assess growth and endocrine function. Abnormal levels may indicate growth disorders, acromegaly, gigantism, or GH deficiency. Doctors order this test to evaluate delayed growth, short stature, excessive growth, or pituitary disease and to monitor GH therapy. Results provide valuable insight into hormone balance, metabolism, and overall endocrine health.

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Blood Draw
Also Known As: Insulin-like Growth Factor 1 Test, Somatomedin-C Test, IGF-I Test

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The LH Test measures luteinizing hormone levels in blood to assess fertility, reproductive health, and endocrine function. Abnormal LH may indicate infertility, menstrual irregularities, menopause, or pituitary disorders in women, and low testosterone or testicular dysfunction in men. Doctors use this test to evaluate ovulation, investigate infertility, monitor puberty disorders, or guide hormone therapy. It provides key insight into reproductive and hormonal balance.

Blood
Blood Draw
Also Known As: Luteinizing Hormone Test, Lutropin Test, Interstitial Cell Stimulating Hormone Test, ICSH Test

The pituitary gland is responsible for regulating hormonal production in the human body. When the gland begins to secrete too much or too little, it often leads to a set of symptoms associated with pituitary disorders. In some cases, the condition involves the presence of a pituitary tumor, which presses against nearby tissues.

The endocrine system is composed of multiple functional and well-integrated parts, including the pituitary gland. Several glands within the human body are interlinked via the endocrine system. These glands produce a variety of hormones to help balance and regulate the body’s natural processes.

This gland is located at the bottom of the brain and behind the sinus cavity. It also sits below the hypothalamus, which is responsible for sending important messages to other parts of the nervous system while regulating the body’s processes. This includes sending hormones designed to start and/or stop the pituitary gland. Once ... See more