Syphilis (RPR)

Syphilis is a bacterial STI caused by Treponema pallidum. It can be silent or present with a painless sore (chancre), a body rash, or vague symptoms, and—without treatment—may lead to serious heart, brain, and nerve problems. Testing is the safest way to know your status and protect partners.

Modern labs use a two-step approach: a nontreponemal screen (most often RPR) and a treponemal confirmatory test. Some labs use a reverse sequence (treponemal screen first, then RPR for titers). Your RPR titer helps ... See more

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The RPR Test with Reflex to Titer and Confirmatory Testing screens for syphilis by detecting non-treponemal antibodies. If reactive, results are automatically followed by a titer to measure antibody concentration and confirmatory treponemal testing for accuracy. Doctors use this test to diagnose active or past syphilis, monitor treatment, or screen at-risk patients. Results provide vital insight into infection status, disease stage, and overall sexual health.

Serum
Phlebotomist
Also Known As: Syphilis Test, Rapid Plasma Reagin Test

The Syphilis Test is an RPR Test with Reflex to Titer and Confirmatory Testing that screens for antibodies to Treponema pallidum. If reactive, additional testing confirms infection and measures antibody levels to assess disease activity. Doctors use this blood test to diagnose syphilis, determine stage, and monitor treatment response. It is widely used in STD screening, prenatal care, and early detection to prevent complications and transmission.

Serum
Phlebotomist
Also Known As: RPR Test with Reflex to Titer and Confirmatory Testing, Rapid Plasma Reagin Test

The RPR (Monitor) with Reflex to Titer Test screens for syphilis by detecting antibodies to Treponema pallidum. If positive, a reflex titer determines antibody concentration to assess disease activity and treatment response. Doctors order this test to diagnose syphilis, monitor therapy, or check reinfection. Results provide essential information for managing active infection, confirming treatment success, and guiding follow-up care.

Also Known As: Syphilis RPR Test, Rapid Plasma Reagin Test

The Syphilis FTA-ABS Test (Fluorescent Treponemal Antibody Absorption) detects antibodies specific to Treponema pallidum, the bacteria that cause syphilis. Doctors use this confirmatory test after a positive screening to verify infection, even in late or latent stages. Results help distinguish syphilis from false positives, guiding diagnosis, treatment, and follow-up. This test is essential for accurate detection and long-term monitoring of syphilis.

Serum
Phlebotomist
Also Known As: Fluorescent Treponemal Antibody Absorption Antibodies Test

The Beta-2-Glycoprotein I IgA Antibody Test detects IgA antibodies targeting beta-2 glycoprotein I, helping identify autoimmune conditions and clotting disorders. Positive results may indicate antiphospholipid syndrome, thrombotic risk, or pregnancy complications. This test provides insight into immune activity, vascular health, and systemic conditions linked to abnormal coagulation and inflammation.

Plasma-Unspecified Vial Pour
Phlebotomist

The Beta-2-Glycoprotein I IgG Antibody Test detects IgG antibodies targeting beta-2 glycoprotein I, helping assess autoimmune disorders and clotting risk. Positive results may indicate antiphospholipid syndrome, pregnancy complications, or thrombotic conditions. This test provides insight into vascular health, immune response, and systemic disorders related to antibody activity and coagulation balance.

Plasma-Unspecified Vial Pour
Phlebotomist

The Beta-2-Glycoprotein I IgM Antibody Test detects IgM antibodies targeting beta-2 glycoprotein I to help assess autoimmune activity and clotting disorders. Positive findings may suggest antiphospholipid syndrome, thrombotic risk, or recurrent miscarriage. This test provides insight into vascular health, immune regulation, and systemic disorders tied to antibody activity and coagulation balance.

Plasma-Unspecified Vial Pour
Phlebotomist

The Obstetric Panel is a prenatal blood test panel that screens for conditions affecting pregnancy and maternal health. It typically includes a Complete Blood Count, blood typing with Rh factor, antibody screen, and infectious disease testing such as hepatitis B, syphilis, rubella, and HIV. Doctors use this panel in early pregnancy to evaluate overall health, identify risks, and ensure safe monitoring for both mother and baby.


The Protein Total and Albumin Test measures overall protein levels and albumin, the main blood protein made by the liver. Abnormal levels may indicate liver disease, kidney disorders, malnutrition, or chronic inflammation. Doctors order this test for patients with swelling, fatigue, or abnormal lab results. Results provide critical insight into nutritional status, liver and kidney function, and help guide diagnosis and treatment of metabolic or chronic conditions.

Serum
Phlebotomist

The Rheumatoid Factor (RF) Test measures RF antibodies in blood to help diagnose rheumatoid arthritis and other autoimmune conditions. High RF levels may indicate rheumatoid arthritis, Sjögren’s syndrome, or other connective tissue diseases, though they can also appear in some infections. Doctors order this test to investigate joint pain, stiffness, or swelling. Results provide important insight into autoimmune activity, joint health, and inflammatory disease management.

Serum
Phlebotomist
Also Known As: RF Test, Rheumatoid Arthritis Factor Test

Plasma-Unspecified Vial Pour
Phlebotomist

Serum
Phlebotomist

Syphilis is an unwanted intruder that has hung around the human species for several thousand years. It's a sexually transmitted infection that appears in different stages. If it's not treated early, the consequences can be life-threatening.

Syphilis tests are the key to early diagnosis, treatment, and recovery. But how can you avoid catching syphilis? Is it curable? How long will symptoms last?

Let's take a closer look at syphilis testing to answer these questions and more.

What Is Syphilis?

Syphilis is a sexually transmitted disease (STD). According to the Centers for Disease Control, it is common, and the infection rate has been increasing in recent years. The Treponema pallidum bacterium causes syphilis.

Syphilis is one of the infectious diseases that a pregnant woman can pass on to her unborn child, known as congenital syphilis.

Risk Factors ... See more