All Heart and Cardiovascular Tests

Heart and cardiovascular tests give you a clear picture of the factors that drive long-term risk and day-to-day symptoms. These labs evaluate cholesterol patterns and particle numbergenetic lipoproteinsinflammationblood-sugar controlkidney health, and cardiac-strain or injury markers.

Use this page to build a right-sized panel. Start with a standard lipid panel and A1c or fasting glucose, then refine risk with ApoB (particle number), lipoprotein(a) [Lp(a)] (genetic risk), and hs-CRP&... See more

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The Activated Protein C-Resistance Test evaluates how blood responds to activated protein C, helping identify resistance often caused by Factor V Leiden mutation. This test supports assessment of abnormal clotting, deep vein thrombosis, and inherited thrombophilia. By measuring clotting response, it provides insight into genetic risks, venous thromboembolism, and overall coagulation health.

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The ADAMTS13 Activity Test with Reflex to Inhibitor measures the activity of the ADAMTS13 enzyme, which regulates von Willebrand factor. Severe deficiency is strongly associated with thrombotic thrombocytopenic purpura (TTP), a rare but life-threatening clotting disorder. Reflex testing for inhibitors helps identify autoimmune causes, supporting evaluation of unexplained anemia, thrombocytopenia, or microvascular thrombosis.


The Adiponectin Test measures adiponectin, a hormone made by fat cells that helps regulate glucose levels and fatty acid breakdown. Low adiponectin is linked to insulin resistance, type 2 diabetes, obesity, and cardiovascular disease. Doctors use this test to evaluate metabolic health, assess risk for diabetes or heart disease, and monitor patients with weight-related or endocrine disorders. Results help guide prevention and treatment strategies.

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Also Known As: Fat Metabolism Test

The ADMA and SDMA Test measures asymmetric and symmetric dimethylarginine, biomarkers of nitric oxide metabolism and endothelial function. Elevated levels are linked to cardiovascular disease, kidney dysfunction, and metabolic disorders. Doctors order this test to assess vascular health, kidney function, or cardiovascular risk. Results provide critical insight into endothelial damage, early detection of disease, and guidance for preventive or therapeutic strategies.

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Also Known As: ADMA/SDMA Test

The Albumin Test measures albumin, the main protein made by the liver that maintains fluid balance and transports hormones, vitamins, and medications. Low albumin may indicate liver disease, kidney problems, malnutrition, or chronic inflammation, while high levels may reflect dehydration. Doctors order this test to evaluate swelling, fatigue, or abnormal labs. Results provide key insight into nutritional status, liver and kidney function, and overall metabolic health.

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Also Known As: ALB Test

The Aldolase Test measures levels of aldolase, an enzyme involved in breaking down glucose for energy. Elevated levels may indicate muscle damage, muscular dystrophy, polymyositis, dermatomyositis, or certain liver diseases. Doctors use this blood test to help diagnose and monitor muscle disorders, evaluate unexplained weakness, and track treatment response. It is often ordered alongside CK and other enzyme tests for a complete evaluation of muscle health.

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The Aldosterone 24 Hour Urine Test evaluates adrenal hormone output across 24 hours, offering information about blood pressure regulation, fluid balance, and electrolyte control. Elevated or low levels may suggest primary aldosteronism, adrenal tumors, or secondary hypertension. This test supports assessment of kidney function, cardiovascular health, and endocrine disorders linked to aldosterone imbalance.

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The Aldosterone Test measures levels of aldosterone, a hormone produced by the adrenal glands that helps regulate blood pressure, sodium, and potassium balance. Abnormal levels may indicate primary aldosteronism, adrenal tumors, kidney disease, or secondary hypertension. Doctors use this blood test to investigate high blood pressure, electrolyte imbalances, or suspected adrenal disorders, helping guide diagnosis, treatment, and long-term patient management.

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Also Known As: Aldosterone Plasma Test

The ALP Test measures alkaline phosphatase enzyme levels in blood to evaluate liver, bone, and bile duct health. High ALP may indicate liver disease, bile duct obstruction, bone disorders, or certain cancers, while low levels may suggest malnutrition or deficiency. Doctors order this test to investigate symptoms like fatigue, abdominal pain, or bone pain and often pair it with other liver function tests. Results provide key insight into metabolic and organ health.

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Also Known As: Alkaline Phosphatase Test, Alk Phos Test, Alkp Test

The Alkaline Phosphatase Isoenzymes Test measures different forms of alkaline phosphatase (ALP) in the blood to determine their source, such as liver, bone, intestine, or placenta. Doctors use this test to evaluate abnormal ALP results, identify liver disease, bile duct obstruction, bone disorders like Paget’s disease, or certain cancers. It helps distinguish between conditions and guides accurate diagnosis and treatment planning.


The Alpha-2-Antiplasmin Test measures the activity of alpha-2-antiplasmin, a key inhibitor of plasmin that regulates fibrinolysis and clot stability. Reduced alpha-2-antiplasmin levels can lead to excessive fibrin breakdown, resulting in bleeding tendencies or delayed clot formation. This test helps evaluate abnormal bleeding, monitor fibrinolytic disorders, and assess the balance of clot formation and dissolution.

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The ALT Test measures alanine aminotransferase, an enzyme mainly found in the liver. Elevated ALT may indicate liver damage from hepatitis, fatty liver disease, cirrhosis, alcohol use, or medication effects. Doctors order this test to evaluate symptoms such as fatigue, abdominal pain, or jaundice and often pair it with AST for accurate liver assessment. Results provide essential insight into liver health, enzyme activity, and overall metabolic function.

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Also Known As: Alanine Aminotransferase Test, GPT Test, SGPT Test, Serum Glutamic Pyruvic Transaminase Test

The ANA Screen IFA with Reflex to Titer and Pattern Test detects antinuclear antibodies in blood to evaluate autoimmune activity. If positive, further testing identifies antibody concentration (titer) and fluorescence pattern, helping diagnose conditions like lupus, rheumatoid arthritis, or Sjögren’s syndrome. Doctors order this test to investigate symptoms such as joint pain, fatigue, rash, or swelling and to guide treatment for autoimmune and connective tissue disorders.

Also Known As: ANA Test, Antinuclear Antibody Screen Test

The ANCA Screen with MPO and PR3 with Reflex to ANCA Titer detects antineutrophil cytoplasmic antibodies linked to autoimmune vasculitis. By targeting myeloperoxidase (MPO) and proteinase 3 (PR3), this test helps evaluate conditions such as granulomatosis with polyangiitis or microscopic polyangiitis. It supports diagnosis, disease activity monitoring, and assessment of autoimmune inflammation.


The ANCA Screen with Reflex to ANCA Titer detects antineutrophil cytoplasmic antibodies, often linked to autoimmune vasculitis such as granulomatosis with polyangiitis and microscopic polyangiitis. If the screen is positive, a titer is performed to measure antibody levels for greater diagnostic accuracy. Doctors use this test to evaluate unexplained inflammation, kidney or lung issues, and guide treatment decisions in autoimmune and systemic vasculitis care.

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Also Known As: ANCA Test, cANCA Test, pANCA Test, Serine Protease 3 Test, Acticytoplasmic Test, 3-ANCA test, PR3-ANCA Test, MPO-ANCA test

The ANCA Vasculitides Test measures antibodies that target neutrophils, helping identify autoimmune vasculitis. It aids in diagnosing conditions including granulomatosis with polyangiitis and microscopic polyangiitis. This test provides insight into systemic inflammation, kidney disease, and respiratory involvement, supporting evaluation of autoimmune disorders linked to vascular and organ damage.

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The Angiotensin Converting Enzyme (ACE) Test measures ACE levels in the blood to help diagnose and monitor sarcoidosis, a condition marked by granulomas in the lungs, lymph nodes, or other organs. Elevated ACE may also be seen in other granulomatous diseases. Doctors use this test to support diagnosis, track disease activity, and evaluate response to therapy, especially when paired with imaging or additional lab studies.

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Also Known As: ACE Test, SACE Test, Serum Angiotensin Converting Enzyme Test

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The Angiotensin II Test evaluates blood levels of a hormone central to the renin-angiotensin-aldosterone system, which regulates blood pressure and electrolyte balance. Abnormal values may indicate hypertension, kidney disease, adrenal dysfunction, or endocrine disorders. Measuring angiotensin II helps identify causes of abnormal blood pressure and supports monitoring of cardiovascular health, guiding clinical assessment of vascular and metabolic conditions.

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The Antithrombin III Activity Test evaluates how effectively antithrombin controls clot formation in the blood. Reduced activity may indicate a hereditary deficiency, abnormal coagulation, or increased risk for venous thrombosis. This test provides insight into clotting disorders, supports diagnosis of thrombophilia, and helps assess vascular health and systemic risks related to impaired anticoagulant activity.

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One person dies every 36 seconds in the United States from cardiovascular disease.

That may seem like a shocking statistic, but what's more surprising is that cardiovascular disease is also the leading cause of death in the US.

Thankfully, by utilizing blood testing for cardiovascular diseases, you can learn your risk factors and make changes in your life to help prevent future heart problems.

So, what is cardiovascular disease, and which heart and cardiovascular tests are used to help diagnose it? Keep reading to learn more about this deadly disease and how to prevent it.

What is Heart and Cardiovascular Disease?

Cardiovascular disease is a type of disease that affects the heart muscle or blood vessels. Heart and Cardiovascular Disease refers to several different conditions, such as heart failure, stroke, heart attack, and more. The most common type of cardiovascular disease in the US is Coronary Artery Disease.

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