All Heart and Cardiovascular Tests

Heart and cardiovascular tests give you a clear picture of the factors that drive long-term risk and day-to-day symptoms. These labs evaluate cholesterol patterns and particle numbergenetic lipoproteinsinflammationblood-sugar controlkidney health, and cardiac-strain or injury markers.

Use this page to build a right-sized panel. Start with a standard lipid panel and A1c or fasting glucose, then refine risk with ApoB (particle number), lipoprotein(a) [Lp(a)] (genetic risk), and hs-CRP&... See more

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The Comprehensive Metabolic Panel (CMP) Test measures 21 markers to assess metabolic health, liver and kidney function, and electrolyte balance. It includes glucose, calcium, sodium, potassium, chloride, CO2, albumin, globulin, A/G ratio, total protein, bilirubin, ALP, AST, ALT, BUN, creatinine, BUN/creatinine ratio, and eGFR. The CMP helps detect diabetes, liver or kidney disease, and supports routine screening and chronic condition monitoring.

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Also Known As: CMP Test, Chemistry Panel Test, Chem Test, Chem 21 Test, Chem 14 Test 

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The Cortisol Total Test measures cortisol levels in blood to assess adrenal gland and pituitary function. Cortisol regulates stress response, metabolism, and immune health. Abnormal results may indicate Cushing’s syndrome, Addison’s disease, or other hormone disorders. Doctors order this test to evaluate symptoms like fatigue, weight changes, weakness, or high blood pressure and to monitor treatment. It provides essential insight into hormone balance and endocrine health.

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Also Known As: Cortisol Blood Test

The Creatine Kinase (CK) Total Test measures CK enzyme levels in blood to detect muscle injury, inflammation, or stress. Elevated CK may indicate muscle disorders, heart attack, strenuous exercise, or conditions such as rhabdomyolysis, while low levels are less common. Doctors use this test to evaluate unexplained muscle pain, weakness, or chest pain and to monitor recovery. It provides insight into muscle, cardiac, and overall metabolic health.

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Also Known As: CK Total Test, Creatine Phosphokinase, CPK Test

The Creatine Kinase (CK) Isoenzymes with Total CK Panel measures overall CK levels and breaks them into isoenzymes (CK-MM, CK-MB, CK-BB) to identify muscle, heart, or brain injury. Elevated CK-MB may suggest a heart attack, while CK-MM points to skeletal muscle damage, and CK-BB indicates brain injury. Doctors order this test for chest pain, muscle weakness, or trauma. Results provide critical insight for diagnosing and monitoring tissue damage.

Also Known As: CPK Isoenzymes Test

The Creatine Kinase Isoenzymes Panel evaluates CK-MM, CK-MB, and CK-BB fractions to differentiate the source of elevated creatine kinase. It aids in diagnosing heart attack, skeletal muscle injury, or central nervous system damage. By analyzing isoenzyme distribution, the test supports clinical evaluation of myocardial infarction, myopathies, neurotrauma, and systemic conditions.

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The Creatine 24 Hour Urine Test measures creatine excretion to evaluate muscle metabolism, kidney function, and possible metabolic disorders. Abnormal levels may indicate muscular dystrophy, kidney impairment, or issues with creatine utilization. By tracking creatine over a full day, this test provides valuable insight into energy metabolism, aiding the assessment of neuromuscular health, renal function, and inherited metabolic conditions.

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The Blood Culture Test detects bacteria or fungi in the bloodstream to diagnose serious infections like sepsis, endocarditis, or systemic fungal infections. Doctors order this test when patients have fever, chills, or low blood pressure. Positive results identify the type of pathogen and guide targeted antibiotic or antifungal treatment. Early detection through blood culture is critical for effective care, preventing complications, and improving patient outcomes.

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Also Known As: Blood Bacteria Test, Fungal Blood Test, Sepsis Test

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The Cyclic Citrullinated Peptide (CCP) IgG Antibody Test helps diagnose rheumatoid arthritis by detecting antibodies strongly linked to autoimmune joint disease. A positive result may indicate early or developing RA, even before symptoms appear. Doctors order this test for patients with joint pain, stiffness, or swelling. Results, often used with the rheumatoid factor (RF) test, provide valuable insight into autoimmune activity and long-term joint health management.

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Also Known As: Anti-CCP, Cyclic Citrullinated Peptide IgG Antibody Test

The Cystatin C Test with eGFR measures blood levels of cystatin C, a protein filtered by the kidneys, and calculates estimated glomerular filtration rate (eGFR). This test provides a sensitive marker for kidney function and can detect early kidney disease, even when creatinine levels are normal. Doctors order it to evaluate chronic kidney disease risk, monitor treatment, and assess overall kidney health in patients with diabetes, hypertension, or other conditions.

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Also Known As: CysX Test, CysC Test

The D-Dimer Test measures fragments of blood clots to help detect abnormal clotting activity. Elevated levels may indicate deep vein thrombosis (DVT), pulmonary embolism (PE), or disseminated intravascular coagulation (DIC). Doctors often order this test when patients have symptoms like leg pain, chest pain, or shortness of breath. Results provide vital insight into clotting risk, helping guide diagnosis and management of thrombotic disorders.

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Also Known As: Fragment D-Dimer Test, Fibrin Degradation Fragment Test

The DCP Test detects des-gamma-carboxy prothrombin, an abnormal form of prothrombin linked to hepatocellular carcinoma and other liver disorders. Elevated levels may reflect tumor activity, chronic liver disease, or cirrhosis. This test provides valuable information for assessing liver function, monitoring cancer progression, and evaluating systemic health in patients with hepatic disease.

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Also Known As: Des-Gamma-Carboxy-Prothrombin Test

The Diabetes Risk Panel with Score combines multiple biomarkers to assess risk of developing type 2 diabetes and related metabolic conditions. By evaluating glucose control, insulin resistance, lipid levels, and inflammation markers, this panel provides a personalized score that reflects overall metabolic health. Clinicians use it to help identify individuals at increased risk, support early intervention, and monitor long-term health.


The Digoxin Test evaluates concentration of digoxin in the bloodstream to help monitor therapy for heart failure and irregular heart rhythms. It ensures medication remains in the therapeutic range, preventing toxicity or reduced effectiveness. By measuring drug levels, this test supports safe cardiac management, assessment of arrhythmias, and ongoing cardiovascular health monitoring.

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The Direct LDL Test measures low-density lipoprotein (LDL) cholesterol directly, without requiring fasting or calculation from triglycerides. LDL is known as “bad cholesterol” because high levels contribute to plaque buildup, heart disease, and stroke risk. Doctors order this test for patients with diabetes, high triglycerides, or cardiovascular risk. Results provide accurate insight into lipid health, helping guide treatment, prevention, and heart disease management.

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Also Known As: Direct LDL Cholesterol Test


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The F2-Isoprostane/Creatinine Ratio Test evaluates urinary F2-isoprostanes adjusted for creatinine to assess oxidative stress and lipid peroxidation. Abnormal findings may reflect risk for cardiovascular disease, diabetes, or neurological disorders. This test provides insight into systemic oxidative damage, metabolic balance, and health conditions influenced by free radical activity.

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The Factor V Leiden Mutation Analysis detects a genetic mutation in the F5 gene that increases risk of abnormal blood clotting (thrombophilia). Individuals with this mutation may be prone to deep vein thrombosis (DVT), pulmonary embolism, or pregnancy complications. Doctors use this DNA test to confirm inherited clotting disorders, assess family risk, and guide prevention strategies, including anticoagulation or lifestyle management.

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Also Known As: Factor 5 Test, Factor V Test

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The Clotting Factor VIII Activity Test measures the activity of factor VIII, a protein essential for normal blood clotting. Low activity may indicate hemophilia A or acquired deficiencies, while elevated activity is linked to clotting risk. This test helps evaluate unexplained bleeding, bruising, or thrombosis, and supports diagnosis of inherited or acquired clotting disorders, providing insight into overall hemostatic function.

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Also Known As: Coag Factor VIII Activity Test

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The Ferritin Test measures ferritin, a protein that stores iron in the body, to evaluate iron levels and detect deficiency or overload. It helps diagnose anemia, iron deficiency, hemochromatosis, and chronic disease-related inflammation. Doctors often order the ferritin test to investigate fatigue, weakness, or unexplained symptoms. It is also used to monitor iron supplementation, treatment effectiveness, and overall iron metabolism health.

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Also Known As: Iron Storage Test

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One person dies every 36 seconds in the United States from cardiovascular disease.

That may seem like a shocking statistic, but what's more surprising is that cardiovascular disease is also the leading cause of death in the US.

Thankfully, by utilizing blood testing for cardiovascular diseases, you can learn your risk factors and make changes in your life to help prevent future heart problems.

So, what is cardiovascular disease, and which heart and cardiovascular tests are used to help diagnose it? Keep reading to learn more about this deadly disease and how to prevent it.

What is Heart and Cardiovascular Disease?

Cardiovascular disease is a type of disease that affects the heart muscle or blood vessels. Heart and Cardiovascular Disease refers to several different conditions, such as heart failure, stroke, heart attack, and more. The most common type of cardiovascular disease in the US is Coronary Artery Disease.

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