Lipid Panel and Comprehensive Metabolic Panel-CMP Most Popular

The Lipid Panel and Comprehensive Metabolic Panel-CMP panel contains 2 tests with 28 biomarkers.

Brief Description: The Lipid Panel and Comprehensive Metabolic Panel test is a combination of two essential sets of blood tests: the Lipid Panel, which evaluates lipid levels in the blood (fats and fatty substances) crucial for determining heart disease risk, and the Comprehensive Metabolic Panel (CMP), which provides a broader overview of body's chemical balance, the health of the kidneys, and the liver's functionality.

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: The patient should be fasting for 9-12 hours prior to collection.

When and Why the Lipid Panel and Comprehensive Metabolic Panel Test May Be Ordered

Healthcare professionals might order this combined panel for various reasons:

  1. Routine Health Assessment: As part of a standard health check-up, to get a holistic understanding of an individual's metabolic health and cardiovascular risk.

  2. Symptom Evaluation: If a patient presents with symptoms suggesting heart disease, kidney disease, liver disease, or metabolic imbalances.

  3. Chronic Condition Monitoring: To track the progress and management of chronic conditions like hypertension, diabetes, or known liver and kidney diseases.

  4. Medication Effects: To monitor potential side effects of medications that might affect liver, kidney, or heart health.

What the Lipid Panel and Comprehensive Metabolic Panel Test Checks For

  • Lipid-related markers: These include Cholesterol (Total, HDL, LDL), Triglycerides, and associated ratios. These markers help determine heart disease risk, with high LDL and triglycerides or low HDL levels often indicating higher risk.

  • Liver markers: This includes Albumin, Globulin, the Albumin/Globulin Ratio, ALP, ALT, AST, and Total Bilirubin. These markers can help identify liver inflammation, damage, or dysfunction.

  • Kidney markers: Urea Nitrogen (BUN), Creatinine, and the Bun/Creatinine Ratio give insight into kidney health and function.

  • Electrolytes: Sodium, Potassium, Chloride, and Carbon Dioxide are essential for muscle function, nerve function, and maintaining the body's proper fluid and acid-base balance.

  • Other metabolic markers: Calcium (related to bone and heart health), Protein (Total, which is a combination of Albumin and Globulin), and glucose (not listed but often included in the CMP, which relates to blood sugar levels and metabolic health).

Other Lab Tests Often Ordered Alongside a Lipid Panel and Comprehensive Metabolic Panel

When a Lipid Panel and Comprehensive Metabolic Panel (CMP) are ordered together, it typically indicates a focus on assessing cardiovascular risk, metabolic function, and overall health status. Additional tests may be ordered to provide a more complete picture of the individual's health, especially related to heart disease, diabetes, and kidney and liver function. Here are some tests commonly ordered alongside these panels:

  1. Hemoglobin A1c (HbA1c):

    • Purpose: To measure the average blood glucose levels over the past two to three months.
    • Why Is It Ordered: To assess for diabetes or prediabetes, as blood sugar control is a crucial aspect of cardiovascular and metabolic health.
  2. Thyroid Function Tests:

    • Purpose: To evaluate thyroid gland function.
    • Why Is It Ordered: Thyroid disorders can affect metabolism, cholesterol levels, and overall cardiovascular risk.
  3. C-Reactive Protein (CRP), High-Sensitivity (hs-CRP):

    • Purpose: To measure CRP, a marker of inflammation in the body.
    • Why Is It Ordered: Elevated hs-CRP is associated with increased cardiovascular risk.
  4. Complete Blood Count (CBC):

    • Purpose: To evaluate overall blood health, including red and white blood cells, and platelets.
    • Why Is It Ordered: To identify any underlying conditions like anemia or infection that can impact overall health.
  5. Urinalysis:

    • Purpose: To test for the presence of substances like protein, glucose, and blood in the urine.
    • Why Is It Ordered: To screen for kidney problems, which can be related to diabetes and hypertension.
  6. Vitamin D Level:

    • Purpose: To measure the level of Vitamin D in the blood.
    • Why Is It Ordered: Vitamin D deficiency has been linked to various health issues, including cardiovascular diseases.
  7. Fasting Insulin and Glucose Tolerance Test:

    • Purpose: To assess insulin resistance and glucose metabolism.
    • Why Is It Ordered: To further evaluate metabolic syndrome and diabetes risk, which are closely related to cardiovascular health.

These tests, when ordered alongside a Lipid Panel and Comprehensive Metabolic Panel, provide a thorough assessment of cardiovascular risk factors, metabolic health, and organ function. They are essential for identifying risk factors for heart disease and diabetes, guiding lifestyle modifications, and determining the need for medical intervention. The specific combination of tests will depend on the individual's risk factors, symptoms, and medical history.

Conditions or Diseases the Lipid Panel and Comprehensive Metabolic Panel Test Can Check For

This combined panel can identify or monitor:

  • Cardiovascular diseases: Including risk for atherosclerosis, coronary artery disease, and other heart-related conditions.

  • Liver diseases: Such as hepatitis and cirrhosis.

  • Kidney disorders: Including chronic kidney disease, glomerulonephritis, and dehydration.

  • Metabolic conditions: Like diabetes, if glucose is also measured.

  • Electrolyte and acid-base imbalances: Such as hyperkalemia (high potassium) or metabolic acidosis.

In conclusion, the Lipid Panel and Comprehensive Metabolic Panel test offers a robust analysis of an individual's cardiovascular risk and overall metabolic health. Given its comprehensive nature, this test is invaluable for both prevention and management of various conditions, ensuring that potential health issues are identified promptly, leading to timely interventions and better health outcomes.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Albumin/Globulin Ratio

The ratio of albumin to globulin (A/G ratio) is calculated from measured albumin and calculated globulin (total protein - albumin). Normally, there is a little more albumin than globulins, giving a normal A/G ratio of slightly over 1. Because disease states affect the relative amounts of albumin and globulin, the A/G ratio may provide a clue as to the cause of the change in protein levels. A low A/G ratio may reflect overproduction of globulins, such as seen in multiple myeloma or autoimmune diseases, or underproduction of albumin, such as may occur with cirrhosis, or selective loss of albumin from the circulation, as may occur with kidney disease (nephrotic syndrome). A high A/G ratio suggests underproduction of immunoglobulins as may be seen in some genetic deficiencies and in some leukemias. More specific tests, such as liver enzyme tests and serum protein electrophoresis, must be performed to make an accurate diagnosis. With a low total protein that is due to plasma expansion (dilution of the blood), the A/G ratio will typically be normal because both albumin and globulin will be diluted to the same extent.

Alkaline Phosphatase

Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone.

Alt

Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.

AST

AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bun/Creatinine Ratio

A ratio between a person’s BUN and blood creatinine to help determine what is causing these concentrations to be higher than normal. The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration. It may also be seen with increased protein, from gastrointestinal bleeding, or increased protein in the diet. The ratio may be decreased with liver disease (due to decrease in the formation of urea) and malnutrition.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.

Carbon Dioxide

CO2 is carbon dioxide. Measures the amount of carbon dioxide in the liquid part of your blood, called the serum. In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.

Chloride

Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance. This is a measure of the amount of chloride in the fluid portion (serum) of the blood.

Creatinine

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys work.

Egfr African American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

Egfr Non-Afr. American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

GFR-AFRICAN AMERICAN

GFR-NON AFRICAN AMERICAN

Globulin

Globulins is the collective term for most blood proteins other than albumin. Identifying the types of globulins can help diagnose certain disorders. Globulins are roughly divided into three groups: alpha, beta, and gamma globulins. Gamma globulines include various types of antibodies such as immunoglobulins (Ig) M, G, and A.

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Potassium

Potassium is a mineral that the body needs to work normally. It helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Protein, Total

The total protein is the total amount of two classes of proteins, albumin and globulin that are found in the fluid portion of your blood. Proteins are important parts of all cells and tissues. Your albumin helps prevent fluid from leaking out of blood vessels and your globulins are an important part of your immune system.

Sodium

Sodium is a substance that the body needs to work properly it is vital to normal body processes, including nerve and muscle function

Urea Nitrogen (Bun)

BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down. BUN measures the amount of urea nitrogen in the blood.

Also known as: Lipid Panel with Ratios (fasting), Lipid Profile with Ratios (fasting), Lipids

Chol/HDLC Ratio

Cholesterol, Total

Cholesterol is a waxy, fat-like substance that occurs naturally in all parts of the body. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can combine with other substances in the blood and stick to the walls of your arteries. This is called plaque. Plaque can narrow your arteries or even block them. High levels of cholesterol in the blood can increase your risk of heart disease. Your cholesterol levels tend to rise as you get older. There are usually no signs or symptoms that you have high blood cholesterol, but it can be detected with a blood test. You are likely to have high cholesterol if members of your family have it, if you are overweight or if you eat a lot of fatty foods. You can lower your cholesterol by exercising more and eating more fruits and vegetables. You also may need to take medicine to lower your cholesterol.

HDL Cholesterol

LDL-Cholesterol

LDL/HDL Ratio

Non HDL Cholesterol

Triglycerides

Triglycerides are a form of fat and a major source of energy for the body. This test measures the amount of triglycerides in the blood. Most triglycerides are found in fat (adipose) tissue, but some triglycerides circulate in the blood to provide fuel for muscles to work. After a person eats, an increased level of triglycerides is found in the blood as the body converts the energy not needed right away into fat. Triglycerides move via the blood from the gut to adipose tissue for storage. In between meals, triglycerides are released from fat tissue to be used as an energy source for the body. Most triglycerides are carried in the blood by lipoproteins called very low density lipoproteins (VLDL). High levels of triglycerides in the blood are associated with an increased risk of developing cardiovascular disease (CVD), although the reason for this is not well understood. Certain factors can contribute to high triglyceride levels and to risk of CVD, including lack of exercise, being overweight, smoking cigarettes, consuming excess alcohol, and medical conditions such as diabetes and kidney disease.
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