* Dr. Kines - Epstein-Barr (EBV) Comprehensive Panel

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For the most comprehensive look at your biomarkers for Epstein-Barr (EBV), we recommend the Epstein-Barr (EBV) Comprehensive Panel, as only one may come out positive:

  • EBV-VCA IgG/IgM (viral capsid antigen): A positive IgG means you’ve had or currently have the infection; A positive IgM means the virus has been reactivated.
  • EBV-EBNA IgG (nuclear antigen): A positive test result is usually associated with past infections.
  • EBV-EA-D IgG (early antigen): A positive EA IgG may mean you have an active or reactivated infection.
  • The Epstein-Barr EBV Early Antigen D Ab IgG test that will let one know if the virus is actively replicating.

Epstein-Barr (EBV) is a virus that causes mononucleosis, also known as the kissing disease, is a viral infection that is thought to be transmitted through the saliva of those who are infected. The Epstein-Barr virus creates an inactive infection in the body where it lies dormant. It can awaken and reactivate itself, even many years after its initial activation.

The reactivated virus has the potential to induce many debilitating autoimmune symptoms. In some, the infection may not be adequately suppressed and may cause or exacerbate autoimmune diseases. 

The Epstein-Barr (EBV) tests are used to figure out if a person has a reactivated infection. 

Reference Range(s)

Epstein-Barr Virus VCA Antibody (IgM)

U/mLInterpretation

  • <36.00 Negative
  • 36.00-43.99 Equivocal
  • >43.99 Positive

Epstein-Barr Virus VCA Antibody (IgG)

U/mLInterpretation

  • <18.00 Negative
  • 18.00-21.99 Equivocal
  • >21.99 Positive


Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody (IgG)

U/mLInterpretation

  • <18.00 Negative
  • 18.00-21.99 Equivocal
  • >21.99 Positive

Epstein-Barr Virus Early Antigen D Antibody (IgG)

U/mLInterpretation

  • <9.00 Negative
  • 9.00-10.99 Equivocal
  • >10.99 Positive