Weekly Promotions

IMPORTANT - Note the Estradiol test included in this panel is not for children that have yet to start their menstrual cycle.  If this test is ordered for a child that has yet to begin their menstrual cycle Quest Diagnostics labs will substitute Estradiol, Free, LC/MS/MS at an additional fee of $290.00

IMPORTANT - Note the Estradiol test included in this panel is not for children that have yet to start their menstrual cycle.  If this test is ordered for a child that has yet to begin their menstrual cycle Quest Diagnostics labs will substitute Estradiol, Free, LC/MS/MS at an additional fee of $290.00

IMPORTANT - Note the Estradiol test included in this panel is not for children that have yet to start their menstrual cycle.  If this test is ordered for a child that has yet to begin their menstrual cycle Quest Diagnostics labs will substitute Estradiol, Free, LC/MS/MS at an additional fee of $290.00

IMPORTANT - Note the Estradiol test included in this panel is not for children that have yet to start their menstrual cycle.  If this test is ordered for a child that has yet to begin their menstrual cycle Quest Diagnostics labs will substitute Estradiol, Free, LC/MS/MS at an additional fee of $290.00

IMPORTANT - Note the Estradiol test included in this panel is not for children that have yet to start their menstrual cycle.  If this test is ordered for a child that has yet to begin their menstrual cycle Quest Diagnostics labs will substitute Estradiol, Free, LC/MS/MS at an additional fee of $290.00

Cardio IQ Lp-PLA2 Activity

Clinical Significance

Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet activating factor Acetylhydrolase, is an inflammatory enzyme that circulates bound mainly to low density lipoproteins and has been found to be localized and enriched in atherosclerotic plaques. In multiple clinical trials, Lp-PLA2 activity has been shown to be an independent predictor of coronary heart disease and stroke in the general population. Measurement of Lp-PLA2 may be used along with traditional cardiovascular risk factor measures for identifying individuals at higher risk of cardiovascular disease events. Clinical management may include beginning or intensifying risk reduction strategies. The activity assay is an enzyme assay run on an automated chemistry platform.

Measuring Lipid Subclasses using Ion Mobility

The way most doctors test for heart disease is with a lipid panel. It helps detect what HDL (good) and LDL (bad) cholesterol are, so hopefully you can reduce your risk of a possible cardiac event such as a heart attack. Nearly half of all heart attack patients were found to have no prior risk which would indicate they were heading toward an attack.

Quest Diagnostics offers advanced cardiovascular tests that help provide a more accurate and individualized picture of risk. The tests look beyond just HDL and LDL cholesterol to identify undiagnosed (or additional) risk.

These advanced cardiovascular tests, along with your lipid panel, will provide more information that you and your doctor can use to understand your complete cardiovascular health.

Lipid Subclasses as measured by Ion Mobility Technology

Knowing what particles make up your LDL and HDL cholesterol may be important. Ion Mobility Technology provides subclass separation that will allow your healthcare provider to identify your cardiovascular risk over time. Following the change in your lipid profile as you respond to diet, exercise and possible medication to reduce your cardiovascular risk is important. Ion Mobility provides the opportunity to determine if treatment is working and if not, optimize the aggressiveness of therapy to hopefully make a difference that can be seen in the Ion Mobility measurement and graphical representation of your LDL and HDL particles. 

Cardio IQ™ Lipoprotein Fractionation, Ion Mobility 
Cardio IQ™ Lipid Panel
Cardio IQ™ Direct LDL 
Cardio IQ™ Apolipoprotein Evaluation 
Cardio IQ™ Lipoprotein (A)

Apo B

• Apo B is a direct measurement of the number of lipoprotein particles, including LDL (“bad cholesterol”), IDL, and VLDL
• A high Apo B number indicates increased risk for heart disease
• Certain medications, improved eating habits, increased physical activity, and loss of body fat are some ways to
  improve Apo B

Lipoprotein (A) - Lp(a)

• High levels of Lp(a) are associated with increased risk of cardiovascular disease and stroke
• Lp(a) levels may be influenced by genetics. Diet and exercise have limited to no effect on lowering Lp(a); however, certain
  medications can lower levels

Cardio IQ® Apolipoprotein Evaluation - (APOLIPOPROTEIN A1, APOLIPOPROTEIN B and APOLIPOPROTEIN B/A1 RATIO)

• Apolipoprotein A1 is the primary protein associated with HDL cholesterol. Like HDL cholesterol, increased concentrations are associated with reduced risk of cardiovascular disease. Apolipoprotein B-100 is the primary protein associated with LDL cholesterol and other lipid particles. Like LDL cholesterol, increased concentrations are associated with increased risk of cardiovascular disease. The ratio of these two apolipoproteins correlates with risk of cardiovascular disease.

Cardio IQ Advanced Lipid Panel Plus and Inflammation Panel

Measuring Lipid Subclasses using Ion Mobility

The way most doctors test for heart disease is with a lipid panel. It helps detect what HDL (good) and LDL (bad) cholesterol are, so hopefully you can reduce your risk of a possible cardiac event such as a heart attack. Nearly half of all heart attack patients were found to have no prior risk which would indicate they were heading toward an attack.

Quest Diagnostics offers advanced cardiovascular tests that help provide a more accurate and individualized picture of risk. The tests look beyond just HDL and LDL cholesterol to identify undiagnosed (or additional) risk.

These advanced cardiovascular tests, along with your lipid panel, will provide more information that you and your doctor can use to understand your complete cardiovascular health.

Lipid Subclasses as measured by Ion Mobility Technology

Knowing what particles make up your LDL and HDL cholesterol may be important. Ion Mobility Technology provides subclass separation that will allow your healthcare provider to identify your cardiovascular risk over time. Following the change in your lipid profile as you respond to diet, exercise and possible medication to reduce your cardiovascular risk is important. Ion Mobility provides the opportunity to determine if treatment is working and if not, optimize the aggressiveness of therapy to hopefully make a difference that can be seen in the Ion Mobility measurement and graphical representation of your LDL and HDL particles. 

Cardio IQ™ Lipoprotein Fractionation, Ion Mobility 

Cardio IQ™ Lipid Panel

Cardio IQ™ Direct LDL 

Cardio IQ™ Apolipoprotein Evaluation 

Cardio IQ™ Lipoprotein (A)

Apo B

• Apo B is a direct measurement of the number of lipoprotein particles, including LDL (“bad cholesterol”), IDL, and VLDL
• A high Apo B number indicates increased risk for heart disease
• Certain medications, improved eating habits, increased physical activity, and loss of body fat are some ways to
  improve Apo B

Lipoprotein (A) - Lp(a)

• High levels of Lp(a) are associated with increased risk of cardiovascular disease and stroke
• Lp(a) levels may be influenced by genetics. Diet and exercise have limited to no effect on lowering Lp(a); however, certain
  medications can lower levels

Cardio IQ® Apolipoprotein Evaluation - (APOLIPOPROTEIN A1, APOLIPOPROTEIN B and APOLIPOPROTEIN B/A1 RATIO)

• Apolipoprotein A1 is the primary protein associated with HDL cholesterol. Like HDL cholesterol, increased concentrations are associated with reduced risk of cardiovascular disease. Apolipoprotein B-100 is the primary protein associated with LDL cholesterol and other lipid particles. Like LDL cholesterol, increased concentrations are associated with increased risk of cardiovascular disease. The ratio of these two apolipoproteins correlates with risk of cardiovascular disease.

Inflammation Panel

hs-CRP

• High levels of C-Reactive Protein (CRP) indicate inflammation due to infection or tissue injury
• Modestly elevated CRP levels may be associated with increased heart disease risk. If both CRP and Lp-PLA2 levels are
  high, your risk for a heart attack or stroke increases significantly
• Certain medications and food may have anti-inflammatory benefits

Lp-PLA2

• High levels of Lp-PLA2 can predict risk of a heart attack or stroke
• When both Lp-PLA2 levels and systolic blood pressure are high, stroke risk increases significantly
• Certain medications can reduce levels of Lp-PLA2 

Cardio IQ® ASCVD Risk Panel with Score 

This panel provides the 10-year and lifetime risk of atherosclerotic cardiovascular disease (ASCVD) using lipid results with anthropomorphic data and family history. 
The ASCVD risk assessment is recommended in the 2013 ACC/AHA Guidelines on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults.

IMPORTANT: For risk calculations to be performed, the following patient-specific information must be provided and recorded at the time of specimen collection:

• Age: Years 
• Gender: M (for male) or F (for female) 
• Height Feet: Feet 
• Height Inches: Inches 
• Weight: lbs 
• Race-African American: Y (for yes) or N (for no) 
• Systolic Blood Pressure: mmHg
• Diastolic Blood Pressure: mmHg
• Treatment for High B.P.: Y (for yes) or N (for no) 
• Diabetes Status: Y (for yes) or N (for no)
• Parental History of Diab: Y (for yes) or N (for no) 
• Smoking Status: Y (for Yes) or N (for no)

Cardio IQ® Diabetes and ASCVD Risk Panel with Scores - Includes:  Cardio IQ® Glucose; Cardio IQ® Hemoglobin A1c; Cardio IQ® Cholesterol, Total; Cardio IQ® HDL Cholesterol; Cardio IQ® Triglycerides; Cardio IQ® Non-HDL and Calculated Components; Cardio IQ® Risks and Personal Factors

If Triglyceride is >400 mg/dL, Cardio IQ® Direct LDL will be performed at an additional charge (CPT code(s): 83721).

Clinical Significance

The increasing prevalence of obesity has led to an epidemic of diabetes mellitus and related complications, including ASCVD. Prediction of the risk of ASCVD and of developing diabetes in the Cardio IQ® lab report will simplify and improve the communication of those risks to patients.

This panel provides the 10-year and lifetime risk of ASCVD events and the 8-year risk of developing diabetes. The lipid panel results will aid in the assessment of ASCVD. Assessment of 10-year risk of a first atherosclerotic cardiovascular (ASCVD) event is recommended by the 2013 ACC/AHA Guidelines on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults. These guidelines recommend initiating statin therapy based on 10-year ASCVD risk score. Assessment of 8-year risk of developing diabetes mellitus is based on laboratory test results with anthropomorphic data and family history. This algorithm was developed in the Framingham cohort, and is intended to aid in the identification of patients at risk for developing diabetes, permitting pharmacological or lifestyle interventions.

IMPORTANT: For risk calculations to be performed, the following patient-specific information must be provided and recorded at the time of specimen collection:

• Age: Years 
• Gender: M (for male) or F (for female) 
• Height Feet: Feet 
• Height Inches: Inches 
• Weight: lbs 
• Race-African American: Y (for yes) or N (for no) 
• Systolic Blood Pressure: mmHg
• Diastolic Blood Pressure: mmHg
• Treatment for High B.P.: Y (for yes) or N (for no) 
• Diabetes Status: Y (for yes) or N (for no)
• Parental History of Diab: Y (for yes) or N (for no) 
• Smoking Status: Y (for Yes) or N (for no)

Lactate Dehydrogenase (LD) (LDH)

Elevations in serum lactate dehydrogenase occur from myocardial infarction, liver disease, pernicious and megaloblastic anemia, pulmonary emboli, malignancies, and muscular dystrophy

This test is useful in the differential diagnosis of male hypogonadism. For males 18 years of age and older only.

Dipstick urinalysis is important in accessing the chemical constituents in the urine and the relationship to various disease states. Microscopic examination helps to detect the presence of cells and other formed elements.

Useful in the diagnosis of hypochromic, microcytic anemias. Decreased in iron deficiency anemia and increased in iron overload.

This test is useful in the differential diagnosis of male hypogonadism. For males 18 years of age and older only.

The ionized calcium is determined by an ion selective electrode methodology. The result that is generated is pH adjusted. The result is empirically based on a measured pH and ionized calcium concentration normalized to a pH of 7.40. This calculation compensates for in vitro changes in pH due to loss of CO2 through specimen handling. Ionized calcium represents the true "bioavailable" calcium in the circulation. In situations where the total calcium is normal but does not fit the clinical picture, e.g., hyperparathyroidism, a determination of the ionized calcium will, many times, show an elevation in the "bioavailable" calcium component. This may be due to alterations in protein concentrations, especially albumin, that binds most of the calcium in the circulation.

Useful in the diagnosis of hypochromic, microcytic anemias. Decreased in iron deficiency anemia and increased in iron overload.

Morley Robbins Magnesium Advocacy Group's 

MAG - Vitamin D (1-25, D2, D3), Mag RBC, & Calcium Panel contains the following tests.

• Calcium, Ionized
• Magnesium, RBC
• QuestAssureD™ 25-Hydroxyvitamin D (D2, D3), LC/MS/MS
• Vitamin D, 1,25-Dihydroxy, LC/MS/MS

• Magnesium RBC (Red Blood Cell): it’s the KEY catalyst for creating “Storage” and “Active” forms of this Hormone…
• 25(OH)D blood test: it’s the measure of the “Storage” form, the precursor to “Active” form of this Hormone…
• 1,25(OH)2 D3 blood test: it’s the measure of the “Active” form of this Hormone…
• “Ionized” Serum Calcium blood test (NOT a standard serum test!): given that Calcitriol’s JOB in the body is to put MORE Calcium into the bloodstream, it only makes sense to know exactly how much you have there already, right?…

Morley Robbins Magnesium Advocacy Group's 

MAG - Magnesium RBC, Zinc, and Copper  Panel contains the following tests.

• Ceruloplasmin
• Copper
• Magnesium, RBC
• Zinc

Patients who were advised to take this test by Morley Robbins and the Magnesium Advocacy Group should notify the lab attendant that the preferred specimen for their Ceruloplasmin and Copper tests is SERUM. The preferred specimen for the Zinc test is PLASMA. Please be aware that it is at the lab’s discretion to decide which specimen type is most appropriate.

Customers should refrain from taking vitamins, or mineral herbal supplements for at least one week before sample collection for Magnesium RBC.

Morley Robbins Magnesium Advocacy Group's 

MAG - Magnesium RBC, Zinc, Copper with Iron Panel contains the following tests.

• Ceruloplasmin
• Copper
• Ferritin
• Iron and Total Iron Binding Capacity (TIBC)
• Magnesium, RBC
• Transferrin
• Zinc

Morley Robbins Magnesium Advocacy Group's 

MAG - Vitamin D (1-25, D2 ,D3), Potassium RBC & Calcium contains the following tests.

• Calcium, Ionized
• Potassium, RBC
• QuestAssureD™ 25-Hydroxyvitamin D (D2, D3), LC/MS/MS
• Vitamin D, 1,25-Dihydroxy, LC/MS/MS
   

Morley Robbins Magnesium Advocacy Group's 

MAG - Iron Panel, Transferrin and Hemoglobin

• Ferritin
• Hemoglobin (Hgb) included in the CBC (includes Differential and Platelets)
• Iron and Total Iron Binding Capacity (TIBC)
• Transferrin

A lipid panel includes:Total cholesterol —this test measures all of the cholesterol in all the lipoprotein particles.High-density lipoprotein cholesterol (HDL-C) — measures the cholesterol in HDL particles; often called "good cholesterol" because it removes excess cholesterol and carries it to the liver for removal.Low-density lipoprotein cholesterol (LDL-C) — calculates the cholesterol in LDL particles; often called "bad cholesterol" because it deposits excess cholesterol in walls of blood vessels, which can contribute to atherosclerosis. Usually, the amount of LDL cholesterol (LDL-C) is calculated using the results of total cholesterol, HDL-C, and triglycerides.Triglycerides — measures all the triglycerides in all the lipoprotein particles; most is in the very low-density lipoproteins (VLDL).Very low-density lipoprotein cholesterol (VLDL-C) — calculated from triglycerides/5; this formula is based on the typical composition of VLDL particles.Non-HDL-C — calculated from total cholesterol minus HDL-C.Cholesterol/HDL ratio — calculated ratio of total cholesterol to HDL-C.

Dipstick urinalysis is important in accessing the chemical constituents in the urine and the relationship to various disease states. Microscopic examination helps to detect the presence of cells and other formed elements.