{"id":2957,"date":"2026-07-27T05:44:00","date_gmt":"2026-07-27T12:44:00","guid":{"rendered":"https:\/\/www.ultalabtests.com\/blog\/?p=2957"},"modified":"2026-07-23T20:48:59","modified_gmt":"2026-07-24T03:48:59","slug":"primary-hyperparathyroidism-high-calcium-pth-test","status":"publish","type":"post","link":"https:\/\/www.ultalabtests.com\/blog\/hormone\/parathyroid-diseases-pth\/primary-hyperparathyroidism-high-calcium-pth-test\/","title":{"rendered":"Primary Hyperparathyroidism: What High Calcium and PTH Reveal"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Primary hyperparathyroidism is a hormone disorder in which one or more parathyroid glands release too much parathyroid hormone, or PTH. The parathyroid glands sit near the thyroid but perform a different job: they help regulate calcium through effects on the bones, kidneys, and intestines. When PTH remains too active, blood calcium can rise while bone mineral is gradually lost and kidney-stone risk may increase.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Many people first encounter this issue when a routine <a href=\"https:\/\/www.ultalabtests.com\/test\/comprehensive-metabolic-panel-test-cmp\">comprehensive metabolic panel<\/a> shows high calcium. The key is not to view calcium as an isolated number. Calcium, albumin, PTH, vitamin D status, kidney function, medications, and the pattern over time all help determine whether the parathyroid glands are responding normally.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.ultalabtests.com\">Ulta Lab Tests<\/a> provides access to many relevant blood and urine tests online where available, which can make confirmation and trend monitoring more convenient. Lab testing provides objective information, but it does not replace a clinician\u2019s diagnosis, imaging, bone-density testing, treatment plan, or medical judgment.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/i0.wp.com\/www.ultalabtests.com\/blog\/wp-content\/uploads\/2026\/07\/primary-hyperparathyroidism-high-calcium-pth-test-square-Large.jpeg?resize=1024%2C1024&#038;quality=100&#038;ssl=1\" alt=\"Woman with highlighted parathyroid glands beside high calcium and PTH blood test graphics for primary hyperparathyroidism.\" class=\"wp-image-2958\" srcset=\"https:\/\/i0.wp.com\/www.ultalabtests.com\/blog\/wp-content\/uploads\/2026\/07\/primary-hyperparathyroidism-high-calcium-pth-test-square-Large.jpeg?resize=1024%2C1024&amp;quality=100&amp;ssl=1 1024w, https:\/\/i0.wp.com\/www.ultalabtests.com\/blog\/wp-content\/uploads\/2026\/07\/primary-hyperparathyroidism-high-calcium-pth-test-square-Large.jpeg?resize=300%2C300&amp;quality=100&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.ultalabtests.com\/blog\/wp-content\/uploads\/2026\/07\/primary-hyperparathyroidism-high-calcium-pth-test-square-Large.jpeg?resize=150%2C150&amp;quality=100&amp;ssl=1 150w, https:\/\/i0.wp.com\/www.ultalabtests.com\/blog\/wp-content\/uploads\/2026\/07\/primary-hyperparathyroidism-high-calcium-pth-test-square-Large.jpeg?resize=768%2C768&amp;quality=100&amp;ssl=1 768w, https:\/\/i0.wp.com\/www.ultalabtests.com\/blog\/wp-content\/uploads\/2026\/07\/primary-hyperparathyroidism-high-calcium-pth-test-square-Large.jpeg?resize=600%2C600&amp;quality=100&amp;ssl=1 600w, https:\/\/i0.wp.com\/www.ultalabtests.com\/blog\/wp-content\/uploads\/2026\/07\/primary-hyperparathyroidism-high-calcium-pth-test-square-Large.jpeg?w=1254&amp;quality=100&amp;ssl=1 1254w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><figcaption class=\"wp-element-caption\">High calcium may reveal a parathyroid hormone pattern. Measuring calcium and PTH together can help guide appropriate follow-up.<\/figcaption><\/figure>\n\n\n\n<h2 id=\"h-key-takeaways\" class=\"wp-block-heading\">Key Takeaways<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Primary hyperparathyroidism is often discovered through an unexpectedly high calcium result before obvious symptoms develop.<\/li>\n\n\n\n<li>When calcium is high, PTH should normally be suppressed. A PTH value within the laboratory reference range may still be \u201cinappropriately normal\u201d and abnormal in context.<\/li>\n\n\n\n<li>The Fifth International Workshop defines hypercalcemic primary hyperparathyroidism using elevated albumin-adjusted calcium with elevated or inappropriately normal <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">intact PTH<\/a> on two occasions at least two weeks apart.<\/li>\n\n\n\n<li>Vitamin D deficiency, chronic kidney disease, malabsorption, medications, and an inherited condition called familial hypocalciuric hypercalcemia can produce confusing or overlapping patterns.<\/li>\n\n\n\n<li>Blood tests help identify the biochemical pattern, while DXA and kidney imaging are needed to assess bone loss, fractures, kidney stones, or calcium deposits.<\/li>\n\n\n\n<li>Severe vomiting, dehydration, confusion, fainting, pronounced weakness, or significant heart-rhythm symptoms require prompt medical assessment rather than routine self-directed retesting.<\/li>\n<\/ul>\n\n\n\n<h2 id=\"h-what-is-primary-hyperparathyroidism\" class=\"wp-block-heading\">What Is Primary Hyperparathyroidism?<\/h2>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>Answer in brief:<\/strong> Primary hyperparathyroidism begins in the parathyroid glands. One or more glands make excess PTH, causing calcium to rise or remain higher than it should be.<\/p>\n<\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\">PTH acts as the body\u2019s calcium regulator. When calcium falls, normal parathyroid glands release PTH to bring it back up. PTH can increase calcium by encouraging release from bone, supporting intestinal calcium absorption through vitamin D pathways, and changing how the kidneys handle calcium and phosphorus.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In primary hyperparathyroidism, this feedback system is disrupted. The most common cause is a benign parathyroid adenoma, a noncancerous growth in one gland. Less often, multiple glands are enlarged or overactive. Parathyroid cancer is rare. NIDDK reports that about eight in ten cases involve a single benign adenoma.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The condition most often affects adults in midlife and later life and is more common in women, although it can occur at any age. Younger age, multigland disease, lifelong high calcium, or a family history can raise concern for an inherited form.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Symptoms alone cannot confirm the condition. Many people have no noticeable symptoms, while fatigue, constipation, weakness, low mood, poor concentration, thirst, and frequent urination can occur in many other health problems. The calcium-PTH relationship provides more specific information than symptoms alone.<\/p>\n\n\n\n<h2 id=\"h-why-primary-hyperparathyroidism-matters-for-your-health\" class=\"wp-block-heading\">Why Primary Hyperparathyroidism Matters for Your Health<\/h2>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>Answer in brief:<\/strong> Persistently excessive PTH can affect the skeleton and kidneys even when a person feels well.<\/p>\n<\/blockquote>\n\n\n\n<h3 id=\"h-bone-health\" class=\"wp-block-heading\">Bone health<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">High PTH can increase the movement of calcium out of bone. Over time, this may contribute to osteopenia, osteoporosis, or fragility fractures. Bone loss can occur at the lumbar spine, hip, and distal one-third radius, which is why guideline-based evaluation uses a three-site DXA rather than relying on a single location.<\/p>\n\n\n\n<h3 id=\"h-kidney-health\" class=\"wp-block-heading\">Kidney health<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Extra calcium filtered through the kidneys may contribute to kidney stones. Primary hyperparathyroidism can also be associated with nephrocalcinosis, meaning calcium deposits in kidney tissue, and with reduced kidney function. A person can have a silent stone or reduced bone density without obvious symptoms.<\/p>\n\n\n\n<h3 id=\"h-calcium-related-symptoms\" class=\"wp-block-heading\">Calcium-related symptoms<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">More marked hypercalcemia may cause nausea, vomiting, constipation, poor appetite, dehydration, excessive thirst, frequent urination, confusion, and pronounced muscle weakness. These symptoms are not unique to parathyroid disease, but they become more concerning when paired with a clearly high calcium result.<\/p>\n\n\n\n<h3 id=\"h-other-health-concerns\" class=\"wp-block-heading\">Other health concerns<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Research continues into possible cardiovascular, quality-of-life, and neurocognitive effects. Current international guidance does not recommend using nonspecific cardiovascular or cognitive findings alone as reasons for parathyroid surgery because the evidence remains inconclusive.<\/p>\n\n\n\n<h2 id=\"h-common-symptoms-risk-factors-and-warning-signs\" class=\"wp-block-heading\">Common Symptoms, Risk Factors, and Warning Signs<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-light-background-color has-background has-fixed-layout\"><thead><tr><th><strong>Symptom or risk factor<\/strong><\/th><th><strong>What it may suggest<\/strong><\/th><th><strong>Tests that may provide more information<\/strong><\/th><\/tr><\/thead><tbody><tr><td>Repeated high calcium on a <a href=\"https:\/\/www.ultalabtests.com\/test\/comprehensive-metabolic-panel-test-cmp\">CMP<\/a><\/td><td>Persistent hypercalcemia that needs confirmation and PTH interpretation<\/td><td><a href=\"https:\/\/www.ultalabtests.com\/test\/comprehensive-metabolic-panel-test-cmp\">Comprehensive Metabolic Panel Test - CMP<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium\">Calcium Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/albumin-alb\">Albumin Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">PTH Intact Test<\/a> , and <a href=\"https:\/\/www.ultalabtests.com\/test\/renal-function-panel\">Renal Function Panel Test<\/a><\/td><\/tr><tr><td>Kidney stones, flank pain, or blood in urine<\/td><td>Increased urinary calcium or another stone-risk disorder<\/td><td><a href=\"https:\/\/www.ultalabtests.com\/test\/renal-function-panel\">Renal Function Panel Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/urinalysis-ua-complete\">Urinalysis Complete Test<\/a> , and <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-24-hour-urine-test-with-creatinine\">Calcium 24 Hour Urine Test with Creatinine<\/a> ; kidney imaging when indicated<\/td><\/tr><tr><td>Osteopenia, osteoporosis, height loss, or low-trauma fracture<\/td><td>Possible skeletal effects of excess PTH or another bone disorder<\/td><td><a href=\"https:\/\/www.ultalabtests.com\/test\/calcium\">Calcium Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">PTH Intact Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/vitamin-d-25-hydroxy-total-test\">Vitamin D 25-Hydroxy Total Immunoassay Test<\/a> , and <a href=\"https:\/\/www.ultalabtests.com\/test\/alkaline-phosphatase-alp\">Alkaline Phosphatase Test<\/a> ; three-site DXA and vertebral imaging when indicated<\/td><\/tr><tr><td>Fatigue, weakness, constipation, thirst, or frequent urination<\/td><td>Possible hypercalcemia, but also many unrelated conditions<\/td><td><a href=\"https:\/\/www.ultalabtests.com\/test\/comprehensive-metabolic-panel-test-cmp\">Comprehensive Metabolic Panel Test - CMP<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium\">Calcium Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/albumin-alb\">Albumin Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">PTH Intact Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/phosphate-as-phosphorus\">Phosphate (as Phosphorus) Test<\/a> , and <a href=\"https:\/\/www.ultalabtests.com\/test\/magnesium-test\">Magnesium Test<\/a> , plus symptom-directed testing<\/td><\/tr><tr><td>High PTH with normal calcium<\/td><td>Often secondary hyperparathyroidism; the normocalcemic form requires careful exclusion<\/td><td>Repeat <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium\">Calcium Test<\/a> and <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\">Calcium Ionized Test<\/a> , plus <a href=\"https:\/\/www.ultalabtests.com\/test\/vitamin-d-25-hydroxy-total-test\">Vitamin D 25-Hydroxy Total Immunoassay Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/renal-function-panel\">Renal Function Panel Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/phosphate-as-phosphorus\">Phosphate (as Phosphorus) Test<\/a> , and malabsorption testing when indicated<\/td><\/tr><tr><td>Lifelong high calcium, low urine calcium, young age, or family history<\/td><td>Familial hypocalciuric hypercalcemia or another inherited condition<\/td><td><a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-24-hour-urine-test-with-creatinine\">Calcium 24 Hour Urine Test with Creatinine<\/a> , clearance-ratio review, and possible genetic evaluation<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>Safety note:<\/strong> Seek prompt medical care for new confusion, fainting, repeated vomiting, inability to stay hydrated, severe weakness, or significant palpitations. Do not wait for routine repeat testing when symptoms are severe or rapidly worsening.<\/p>\n<\/blockquote>\n\n\n\n<h2 id=\"h-when-to-consider-testing\" class=\"wp-block-heading\">When to Consider Testing<\/h2>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>Answer in brief:<\/strong> Testing may be reasonable after repeated high calcium, kidney stones, unexplained bone loss or fracture, high PTH, reduced kidney function, or symptoms that occur alongside an abnormal calcium result.<\/p>\n<\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\">Consider discussing a focused calcium-PTH evaluation with a healthcare professional when:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>calcium is above range on more than one blood test;<\/li>\n\n\n\n<li>a routine <a href=\"https:\/\/www.ultalabtests.com\/test\/comprehensive-metabolic-panel-test-cmp\">CMP<\/a> shows high calcium and no clear temporary explanation;<\/li>\n\n\n\n<li>kidney stones are recurrent or unexplained;<\/li>\n\n\n\n<li>osteopenia, osteoporosis, or a low-trauma fracture is present;<\/li>\n\n\n\n<li>PTH is elevated with normal calcium;<\/li>\n\n\n\n<li>kidney function is reduced;<\/li>\n\n\n\n<li>there is a personal or family history of lifelong hypercalcemia;<\/li>\n\n\n\n<li>calcium-related symptoms occur with an abnormal laboratory result; or<\/li>\n\n\n\n<li>pregnancy is present or planned and calcium or PTH is abnormal, because interpretation and management require specialist oversight.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Testing should be targeted rather than broad. Cardiometabolic markers such as the <a href=\"https:\/\/www.ultalabtests.com\/test\/a1c-test\">A1c Test<\/a> and <a href=\"https:\/\/www.ultalabtests.com\/test\/lipid-panel-test\">Lipid Panel Test<\/a> , sex hormones, or autoimmune panels may be useful for separate health questions, but they do not establish primary hyperparathyroidism.<\/p>\n\n\n\n<h2 id=\"h-the-role-of-lab-testing\" class=\"wp-block-heading\">The Role of Lab Testing<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Lab testing helps confirm that calcium is persistently high, determines whether PTH is appropriately suppressed, checks vitamin D and kidney function, and guides urine-calcium assessment. Trends are often more informative than a single result because hydration, albumin, medications, supplements, illness, and laboratory variation can affect values.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Blood and urine tests cannot measure bone density, identify every kidney stone, or locate an abnormal gland. DXA and kidney imaging may be needed. Neck ultrasound, sestamibi scanning, and other localization studies are for surgical planning after the biochemical diagnosis is established, not for initial screening.<\/p>\n\n\n\n<h3 id=\"h-how-the-core-calcium-pth-patterns-fit-together\" class=\"wp-block-heading\">How the Core Calcium-PTH Patterns Fit Together<\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-background has-fixed-layout\" style=\"background:linear-gradient(135deg,rgb(252,185,0) 66%,rgb(255,105,0) 100%)\"><thead><tr><th><strong>Laboratory pattern<\/strong><\/th><th><strong>General interpretation<\/strong><\/th><th><strong>Important next considerations<\/strong><\/th><\/tr><\/thead><tbody><tr><td>High calcium with high or inappropriately normal PTH<\/td><td>Parathyroid-dependent hypercalcemia; classic pattern of primary hyperparathyroidism<\/td><td>Confirm on repeat testing with albumin; assess vitamin D, kidney function, urine calcium, bones, and kidneys<\/td><\/tr><tr><td>High calcium with suppressed PTH<\/td><td>Points away from primary hyperparathyroidism<\/td><td>Clinician-directed evaluation for non-parathyroid causes such as malignancy-related hypercalcemia, excess vitamin D activity, granulomatous disease, or medication effects<\/td><\/tr><tr><td>High PTH with normal calcium<\/td><td>Often a secondary response rather than primary disease<\/td><td>Exclude vitamin D deficiency, chronic kidney disease, low calcium intake, malabsorption, bariatric surgery, and medication effects; repeat total and <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\">ionized calcium<\/a><\/td><\/tr><tr><td>High calcium with unexpectedly low urine calcium<\/td><td>May suggest familial hypocalciuric hypercalcemia<\/td><td>Review 24-hour collection quality, kidney function, vitamin D, thiazide or lithium use; consider clearance-ratio and genetic evaluation<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Normocalcemic primary hyperparathyroidism is a diagnosis of exclusion. The Fifth International Workshop describes it as normal adjusted total and <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\">ionized calcium<\/a> with elevated PTH on at least two occasions over three to six months, after alternative causes of secondary hyperparathyroidism have been ruled out.<\/p>\n\n\n\n<h2 id=\"h-related-lab-tests-and-biomarkers\" class=\"wp-block-heading\">Related Lab Tests and Biomarkers<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-light-background-color has-background has-fixed-layout\"><thead><tr><th><strong>Lab test or biomarker<\/strong><\/th><th><strong>What it measures and why it matters<\/strong><\/th><th><strong>General result pattern<\/strong><\/th><th><strong>Important limitations and relevant Ulta Lab Tests option<\/strong><\/th><\/tr><\/thead><tbody><tr><td><a href=\"https:\/\/www.ultalabtests.com\/test\/calcium\">Calcium Test<\/a> and <a href=\"https:\/\/www.ultalabtests.com\/test\/albumin-alb\">Albumin Test<\/a><\/td><td>Calcium is often the first clue; albumin helps interpret protein-bound calcium.<\/td><td>Persistent high calcium supports hypercalcemia, but dehydration, medications, and non-parathyroid causes remain possible.<\/td><td>Interpret together and repeat when appropriate. See the <a href=\"https:\/\/www.ultalabtests.com\/test\/comprehensive-metabolic-panel-test-cmp\"><strong>Comprehensive Metabolic Panel Test - CMP<\/strong><\/a> .<\/td><\/tr><tr><td><a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">PTH Intact Test<\/a><\/td><td>Shows whether the parathyroid response matches the calcium level.<\/td><td>High or nonsuppressed PTH with high calcium supports a parathyroid-driven pattern; high PTH with normal or low calcium often reflects a secondary cause.<\/td><td>Must be read with calcium, vitamin D, and kidney function; biotin may interfere with some assays. See the <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\"><strong>PTH Intact Test<\/strong><\/a> .<\/td><\/tr><tr><td><a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\">Calcium Ionized Test<\/a> or <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test-with-ionized-calcium\">PTH Intact Test with Ionized Calcium<\/a><\/td><td>Measures unbound, biologically active calcium.<\/td><td>High <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\">ionized calcium<\/a> supports true hypercalcemia and can clarify a discordant total-calcium result.<\/td><td>Handling and pH affect the specimen; it is not needed in every case. See the <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\"><strong>Calcium Ionized Test<\/strong><\/a> or <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test-with-ionized-calcium\"><strong>PTH Intact Test with Ionized Calcium<\/strong><\/a> .<\/td><\/tr><tr><td><a href=\"https:\/\/www.ultalabtests.com\/test\/phosphate-as-phosphorus\">Phosphate (as Phosphorus) Test<\/a> and <a href=\"https:\/\/www.ultalabtests.com\/test\/vitamin-d-25-hydroxy-total-test\">Vitamin D 25-Hydroxy Total Immunoassay Test<\/a><\/td><td>Phosphorus reflects PTH and kidney handling; <a href=\"https:\/\/www.ultalabtests.com\/test\/vitamin-d-25-hydroxy-total-test\">25-hydroxyvitamin D<\/a> assesses vitamin D status.<\/td><td>Phosphorus may be low or low-normal in primary disease. Low vitamin D can raise PTH and mimic or worsen a secondary pattern.<\/td><td>Neither result diagnoses the condition alone. See the <a href=\"https:\/\/www.ultalabtests.com\/test\/phosphate-as-phosphorus\"><strong>Phosphate (as Phosphorus) Test<\/strong><\/a> and <a href=\"https:\/\/www.ultalabtests.com\/test\/vitamin-d-25-hydroxy-total-test\"><strong>Vitamin D 25-Hydroxy Total Immunoassay Test<\/strong><\/a> .<\/td><\/tr><tr><td><a href=\"https:\/\/www.ultalabtests.com\/test\/creatinine\">Creatinine Test<\/a> and <a href=\"https:\/\/www.ultalabtests.com\/test\/renal-function-panel\">Renal Function Panel Test<\/a><\/td><td>Estimate kidney filtration and help identify kidney-related secondary hyperparathyroidism or renal involvement.<\/td><td>Reduced eGFR may raise PTH and is also a marker of kidney complications.<\/td><td>eGFR varies with age, muscle mass, hydration, and method. Included in the <a href=\"https:\/\/www.ultalabtests.com\/test\/comprehensive-metabolic-panel-test-cmp\">CMP<\/a> and <a href=\"https:\/\/www.ultalabtests.com\/test\/renal-function-panel\"><strong>Renal Function Panel Test<\/strong><\/a> .<\/td><\/tr><tr><td><a href=\"https:\/\/www.ultalabtests.com\/test\/magnesium-test\">Magnesium Test<\/a> and <a href=\"https:\/\/www.ultalabtests.com\/test\/alkaline-phosphatase-alp\">Alkaline Phosphatase Test<\/a><\/td><td>Magnesium participates in calcium-PTH regulation; alkaline phosphatase can reflect bone or liver activity.<\/td><td>Abnormal magnesium may complicate interpretation; high alkaline phosphatase may reflect bone turnover or liver\/biliary disease.<\/td><td>Neither is specific. See the <a href=\"https:\/\/www.ultalabtests.com\/test\/magnesium-test\"><strong>Magnesium Test<\/strong><\/a> and <a href=\"https:\/\/www.ultalabtests.com\/test\/alkaline-phosphatase-alp\"><strong>Alkaline Phosphatase Test<\/strong><\/a> .<\/td><\/tr><tr><td><a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-24-hour-urine-test-with-creatinine\">Calcium 24 Hour Urine Test with Creatinine<\/a><\/td><td>Assesses daily calcium excretion, collection completeness, stone risk, and possible FHH.<\/td><td>High urine calcium may indicate hypercalciuria; very low calcium relative to creatinine may favor FHH.<\/td><td>Incomplete collection, kidney disease, vitamin D deficiency, thiazides, and lithium can distort results. See the <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-24-hour-urine-test-with-creatinine\"><strong>Calcium 24 Hour Urine Test with Creatinine<\/strong><\/a> .<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 id=\"h-tests-beyond-blood-and-urine\" class=\"wp-block-heading\">Tests Beyond Blood and Urine<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A complete assessment may require:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>three-site DXA of the lumbar spine, hip, and distal one-third radius;<\/li>\n\n\n\n<li>vertebral fracture assessment or spine imaging when indicated;<\/li>\n\n\n\n<li>kidney imaging for nephrolithiasis or nephrocalcinosis; and<\/li>\n\n\n\n<li>a more extensive kidney-stone risk evaluation when stones are present.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Direct-access laboratory testing can reveal the biochemical signal, but it cannot replace these imaging and bone-density studies.<\/p>\n\n\n\n<h2 id=\"h-recommended-testing-approach\" class=\"wp-block-heading\">Recommended Testing Approach<\/h2>\n\n\n\n<h3 id=\"h-1-essential-confirmation-tests\" class=\"wp-block-heading\">1. Essential confirmation tests<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A focused first step commonly includes the <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium\">Calcium Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/albumin-alb\">Albumin Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">PTH Intact Test<\/a> drawn at the same time, <a href=\"https:\/\/www.ultalabtests.com\/test\/renal-function-panel\">Renal Function Panel Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/phosphate-as-phosphorus\">Phosphate (as Phosphorus) Test<\/a> , and <a href=\"https:\/\/www.ultalabtests.com\/test\/vitamin-d-25-hydroxy-total-test\">Vitamin D 25-Hydroxy Total Immunoassay Test<\/a> . This confirms the calcium-PTH relationship and checks two common confounders: vitamin D deficiency and impaired kidney function.<\/p>\n\n\n\n<h3 id=\"h-2-clarifying-or-advanced-tests\" class=\"wp-block-heading\">2. Clarifying or advanced tests<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\">Calcium Ionized Test<\/a> may help when total calcium and the clinical picture do not agree or when normocalcemic primary hyperparathyroidism is being considered. Depending on history, additional testing may include the <a href=\"https:\/\/www.ultalabtests.com\/test\/magnesium-test\">Magnesium Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/alkaline-phosphatase-alp\">Alkaline Phosphatase Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-24-hour-urine-test-with-creatinine\">Calcium 24 Hour Urine Test with Creatinine<\/a> , celiac or other malabsorption testing, and genetic evaluation for people younger than 30, multigland disease, lifelong hypercalcemia, or a family or syndromic history.<\/p>\n\n\n\n<h3 id=\"h-3-complication-assessment-and-monitoring\" class=\"wp-block-heading\">3. Complication assessment and monitoring<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Once the biochemical pattern is established, evaluation may include three-site DXA, vertebral assessment, kidney imaging, and stone-risk testing. For people monitored without surgery, the Fifth International Workshop recommends clinician-supervised annual <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium\">Calcium Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/vitamin-d-25-hydroxy-total-test\">Vitamin D 25-Hydroxy Total Immunoassay Test<\/a> , and <a href=\"https:\/\/www.ultalabtests.com\/test\/renal-function-panel\">Renal Function Panel Test<\/a> ; <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">PTH Intact Test<\/a> when indicated; and DXA every one to two years unless a longer interval is appropriate.<\/p>\n\n\n\n<h2 id=\"h-how-to-understand-your-results\" class=\"wp-block-heading\">How to Understand Your Results<\/h2>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>Answer in brief:<\/strong> Interpret calcium and PTH together, not as separate \u201cnormal\u201d or \u201cabnormal\u201d flags.<\/p>\n<\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\">Reference ranges vary by assay, units, and population. A slightly abnormal value does not prove disease, while a PTH marked \u201cnormal\u201d does not rule out primary hyperparathyroidism when calcium is high because normal physiology should suppress PTH.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Albumin can change total-calcium interpretation, and <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\">ionized calcium<\/a> may help when albumin is abnormal or the result does not fit the clinical picture. Hydration, pregnancy, kidney function, recent illness, medications, supplements, timing, and laboratory methodology can also affect results.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Thiazides and lithium can alter calcium-PTH patterns. Calcium, vitamin D, calcium-containing antacids, bisphosphonates, and denosumab may complicate interpretation. Biotin can produce a falsely low PTH result in some assays; the Fifth International Workshop notes that a 48-hour pause has been suggested. Follow test-specific instructions and do not stop prescribed medicine without guidance.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The guideline defines hypercalcemic primary hyperparathyroidism using elevated albumin-adjusted calcium with elevated or inappropriately normal <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">intact PTH<\/a> on two occasions at least two weeks apart. For established disease, it recommends maintaining <a href=\"https:\/\/www.ultalabtests.com\/test\/vitamin-d-25-hydroxy-total-test\">25-hydroxyvitamin D<\/a> above 30 ng\/mL and below the laboratory upper limit through cautious, clinician-guided supplementation.<\/p>\n\n\n\n<h2 id=\"h-when-is-parathyroid-surgery-discussed\" class=\"wp-block-heading\">When Is Parathyroid Surgery Discussed?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Parathyroidectomy is the definitive treatment. The decision is individualized with a qualified clinician and, when appropriate, an experienced parathyroid surgeon.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Fifth International Workshop recommends surgery for symptomatic disease and advises discussion when any one of these findings is present in otherwise asymptomatic disease:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>calcium consistently more than 1 mg\/dL above the upper limit of normal;<\/li>\n\n\n\n<li>a vertebral or other fragility fracture, or a DXA T-score of -2.5 or lower;<\/li>\n\n\n\n<li>eGFR or creatinine clearance below 60 mL\/min;<\/li>\n\n\n\n<li>kidney stones or nephrocalcinosis;<\/li>\n\n\n\n<li>24-hour urine calcium above about 250 mg\/day in women or 300 mg\/day in men; or<\/li>\n\n\n\n<li>age younger than 50 years.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">These criteria guide a clinical discussion, not self-diagnosis. Preoperative imaging locates abnormal glands after biochemical confirmation; a negative scan does not exclude the condition.<\/p>\n\n\n\n<h2 id=\"h-how-ulta-lab-tests-helps\" class=\"wp-block-heading\">How Ulta Lab Tests Helps<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Ulta Lab Tests allows consumers to order many relevant blood and urine tests online where available. Testing is performed through established laboratory networks such as Quest Diagnostics where applicable. Pricing is shown before ordering, insurance is not required, HSA or FSA payment may be available for eligible purchases, and results are delivered through a secure online account.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Direct access can make confirmation and trend review more convenient, but Ulta Lab Tests does not diagnose primary hyperparathyroidism, determine whether surgery is needed, or replace imaging, DXA, or professional medical care.<\/p>\n\n\n\n<h2 id=\"h-patient-education-preparing-for-testing\" class=\"wp-block-heading\">Patient Education: Preparing for Testing<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Check instructions for the exact order; fasting or timing requirements may vary.<\/li>\n\n\n\n<li>Maintain ordinary hydration unless told otherwise, because dehydration can raise total calcium.<\/li>\n\n\n\n<li>List thiazides, lithium, calcium, vitamin D, calcium-containing antacids, bisphosphonates, denosumab, and biotin products.<\/li>\n\n\n\n<li>Do not change prescribed therapy on your own; ask whether any medicine or supplement may affect testing.<\/li>\n\n\n\n<li>Follow 24-hour urine instructions exactly because missed collections can make the result unreliable.<\/li>\n\n\n\n<li>Bring prior calcium, PTH, vitamin D, kidney-function, stone, and bone-density results for trend review.<\/li>\n<\/ul>\n\n\n\n<h2 id=\"h-questions-to-ask-your-healthcare-provider\" class=\"wp-block-heading\">Questions to Ask Your Healthcare Provider<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Is my calcium truly elevated after considering albumin, hydration, and repeat testing?<\/li>\n\n\n\n<li>Is my PTH appropriately suppressed for the calcium level?<\/li>\n\n\n\n<li>Do I need <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\">ionized calcium<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-24-hour-urine-test-with-creatinine\">24-hour urine calcium and creatinine<\/a> , or genetic evaluation?<\/li>\n\n\n\n<li>Could vitamin D deficiency, kidney disease, malabsorption, medications, or supplements explain the pattern?<\/li>\n\n\n\n<li>Have my kidneys and bones been assessed with appropriate imaging and DXA?<\/li>\n\n\n\n<li>Do I meet criteria for a surgical discussion, or is clinician-supervised monitoring reasonable?<\/li>\n<\/ul>\n\n\n\n<h2 id=\"h-frequently-asked-questions\" class=\"wp-block-heading\">Frequently Asked Questions<\/h2>\n\n\n\n<h3 id=\"h-what-blood-tests-are-used-for-primary-hyperparathyroidism\" class=\"wp-block-heading\">What blood tests are used for primary hyperparathyroidism?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The core tests are the <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium\">Calcium Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/albumin-alb\">Albumin Test<\/a> , and <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">PTH Intact Test<\/a> measured together. The <a href=\"https:\/\/www.ultalabtests.com\/test\/comprehensive-metabolic-panel-test-cmp\">Comprehensive Metabolic Panel Test - CMP<\/a> also provides kidney markers. The <a href=\"https:\/\/www.ultalabtests.com\/test\/phosphate-as-phosphorus\">Phosphate (as Phosphorus) Test<\/a> and <a href=\"https:\/\/www.ultalabtests.com\/test\/vitamin-d-25-hydroxy-total-test\">Vitamin D 25-Hydroxy Total Immunoassay Test<\/a> help clarify mineral balance and secondary causes. The <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\">Calcium Ionized Test<\/a> may help when total calcium is difficult to interpret or the normocalcemic form is being considered.<\/p>\n\n\n\n<h3 id=\"h-can-a-normal-pth-still-indicate-primary-hyperparathyroidism\" class=\"wp-block-heading\">Can a normal PTH still indicate primary hyperparathyroidism?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Yes. When calcium is high, normal parathyroid glands should reduce PTH. A value inside the laboratory range may therefore be \u201cinappropriately normal\u201d if it is not suppressed. Calcium and PTH must be interpreted together rather than treating each reference-range flag as a separate answer.<\/p>\n\n\n\n<h3 id=\"h-how-many-high-calcium-results-are-needed\" class=\"wp-block-heading\">How many high calcium results are needed?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The Fifth International Workshop defines hypercalcemic primary hyperparathyroidism using elevated albumin-adjusted calcium plus elevated or inappropriately normal <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">intact PTH<\/a> on two occasions at least two weeks apart. Timing may differ when calcium is markedly high, symptoms are concerning, or medication and hydration effects must be addressed.<\/p>\n\n\n\n<h3 id=\"h-what-does-high-pth-with-normal-calcium-mean\" class=\"wp-block-heading\">What does high PTH with normal calcium mean?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">It is often secondary hyperparathyroidism from vitamin D deficiency, chronic kidney disease, low calcium intake, malabsorption, bariatric surgery, or medication effects. Normocalcemic primary hyperparathyroidism is considered only after total and <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\">ionized calcium<\/a> remain normal, PTH stays elevated, and these alternatives have been excluded.<\/p>\n\n\n\n<h3 id=\"h-why-is-vitamin-d-tested-when-calcium-is-high\" class=\"wp-block-heading\">Why is vitamin D tested when calcium is high?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Low vitamin D can stimulate extra PTH production and confuse interpretation. It also matters for bone health. In established primary hyperparathyroidism, supplementation should be individualized and monitored rather than used in large, unsupervised doses to correct the calcium-PTH pattern.<\/p>\n\n\n\n<h3 id=\"h-what-does-low-calcium-in-a-24-hour-urine-collection-mean\" class=\"wp-block-heading\">What does low calcium in a 24-hour urine collection mean?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Unexpectedly low urine calcium may suggest familial hypocalciuric hypercalcemia, especially with lifelong mild hypercalcemia or family history. Kidney disease, vitamin D deficiency, thiazides, lithium, and incomplete collection can also lower it, so a clearance ratio and sometimes genetic evaluation are needed.<\/p>\n\n\n\n<h3 id=\"h-can-lab-tests-show-whether-my-bones-or-kidneys-are-affected\" class=\"wp-block-heading\">Can lab tests show whether my bones or kidneys are affected?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">They can show kidney filtration, urinary calcium, and mineral patterns, but they cannot fully assess target-organ damage. DXA measures bone density, vertebral imaging can identify fractures, and kidney imaging can detect stones or nephrocalcinosis. These studies may be needed even without symptoms.<\/p>\n\n\n\n<h3 id=\"h-do-i-need-to-fast-and-can-i-order-these-tests-directly\" class=\"wp-block-heading\">Do I need to fast, and can I order these tests directly?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Many calcium and PTH tests do not require fasting, but instructions vary by laboratory and panel. Ulta Lab Tests offers many relevant tests for direct online ordering where available. Follow the exact preparation instructions and review results with a qualified healthcare provider.<\/p>\n\n\n\n<h3 id=\"h-when-is-high-calcium-urgent-and-should-i-simply-retest\" class=\"wp-block-heading\">When is high calcium urgent, and should I simply retest?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">New confusion, fainting, repeated vomiting, inability to hydrate, severe weakness, or significant rhythm symptoms require prompt medical assessment. Repeat testing is often useful for mild or unclear abnormalities, but a markedly high result or concerning symptoms should not be managed through routine self-directed retesting alone.<\/p>\n\n\n\n<h2 id=\"h-conclusion\" class=\"wp-block-heading\">Conclusion<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Primary hyperparathyroidism is a hormone pattern, not a single abnormal number. Persistent high calcium with PTH that is elevated or insufficiently suppressed can point to a parathyroid-driven process, while vitamin D, kidney function, medications, urine calcium, and family history help distinguish look-alike conditions.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Explore <a href=\"https:\/\/www.ultalabtests.com\/testing\/categories\/hormone\/parathyroid-diseases\">parathyroid hormone and calcium tests<\/a> through <a href=\"https:\/\/www.ultalabtests.com\">UltaLabTests.com<\/a> , and review results with a qualified healthcare provider who can integrate laboratory data with symptoms, medications, DXA, and imaging.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.ultalabtests.com\/testing\/categories\/hormone\/parathyroid-diseases\">Explore Parathyroid and Calcium Tests<\/a><\/p>\n\n\n\n<h2 id=\"h-references\" class=\"wp-block-heading\">References<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>National Institute of Diabetes and Digestive and Kidney Diseases. <a href=\"https:\/\/www.niddk.nih.gov\/health-information\/endocrine-diseases\/primary-hyperparathyroidism\" target=\"_blank\" rel=\"noreferrer noopener\">Primary Hyperparathyroidism<\/a><\/li>\n\n\n\n<li>Bilezikian JP, Khan AA, Silverberg SJ, et al. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36245251\/\" target=\"_blank\" rel=\"noreferrer noopener\">Evaluation and Management of Primary Hyperparathyroidism: Summary Statement and Guidelines from the Fifth International Workshop<\/a><\/li>\n\n\n\n<li>Journal of Bone and Mineral Research, Oxford Academic. <a href=\"https:\/\/academic.oup.com\/jbmr\/article\/37\/11\/2293\/7512381\" target=\"_blank\" rel=\"noreferrer noopener\">Full-text Fifth International Workshop guideline<\/a><\/li>\n\n\n\n<li>MedlinePlus.<\/li>\n\n\n\n<li>MedlinePlus. <\/li>\n<\/ol>\n\n\n\n<h2 id=\"h-summary\" class=\"wp-block-heading\">Summary<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Primary hyperparathyroidism is a disorder in which one or more parathyroid glands release excess PTH, often causing blood calcium to rise. The most informative clue is high calcium paired with PTH that is elevated or not appropriately suppressed.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Confirm high calcium with repeat total calcium and albumin.<\/li>\n\n\n\n<li>Measure <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">intact PTH<\/a> at the same time because a normal-range PTH can still be abnormal when calcium is high.<\/li>\n\n\n\n<li>Check <a href=\"https:\/\/www.ultalabtests.com\/test\/vitamin-d-25-hydroxy-total-test\">25-hydroxyvitamin D<\/a> , phosphorus, and kidney function to identify secondary causes and complications.<\/li>\n\n\n\n<li>Use <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-24-hour-urine-test-with-creatinine\">24-hour urine calcium and creatinine<\/a> when needed to assess hypercalciuria and distinguish primary hyperparathyroidism from FHH.<\/li>\n\n\n\n<li>Assess bone density and kidney imaging separately because blood tests cannot detect all fractures, bone loss, or stones.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Related lab tests: <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium\">Calcium Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/albumin-alb\">Albumin Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/comprehensive-metabolic-panel-test-cmp\">Comprehensive Metabolic Panel Test - CMP<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/pth-intact-test\">PTH Intact Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-ionized-test\">Calcium Ionized Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/phosphate-as-phosphorus\">Phosphate (as Phosphorus) Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/vitamin-d-25-hydroxy-total-test\">Vitamin D 25-Hydroxy Total Immunoassay Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/renal-function-panel\">Renal Function Panel Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/magnesium-test\">Magnesium Test<\/a> , <a href=\"https:\/\/www.ultalabtests.com\/test\/alkaline-phosphatase-alp\">Alkaline Phosphatase Test<\/a> , and <a href=\"https:\/\/www.ultalabtests.com\/test\/calcium-24-hour-urine-test-with-creatinine\">Calcium 24 Hour Urine Test with Creatinine<\/a> .<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ulta Lab Tests helps patients access many of these tests online where available, with transparent ordering and secure online results for informed provider discussions.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Disclaimer:<\/strong> Lab testing is informational and should be interpreted with a qualified healthcare provider; it does not replace diagnosis, imaging, or treatment planning.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Primary hyperparathyroidism is a hormone disorder in which one or more parathyroid glands release too much parathyroid hormone, or PTH. The parathyroid glands sit near the thyroid but perform a different job: they help regulate 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