TORCH Panel

The TORCH Panel panel contains 5 tests with 6 biomarkers.

TORCH Panel

  • Cytomegalovirus Antibody (IgG)
  • Cytomegalovirus Antibody (IgM)
  • Herpes Simplex Virus 1/2 (IgG), Type-Specific Antibodies (HerpeSelect®)
  • Rubella Immune Status
  • Toxoplasma Antibody (IgG)

TORCH is an acronym for a group of infectious diseases that can cause illness in pregnant women and may cause birth defects in their newborns. The TORCH panel is a group of blood tests that detect the presence of antibodies produced by the immune system in response to these infections. Confirmation of an active infection may require more specific tests.

The following tests make up the TORCH panel: Toxoplasmosis, Rubella, Cytomegalovirus, and Herpes simplex virus.

Toxoplasmosis is a parasitic infection that can be passed from mother to baby through the placenta during pregnancy. An infection with Toxoplasma gondii can cause eye and central nervous system infections as well as brain and muscle cysts. If acquired during the pregnancy, it may result in a miscarriage or cause birth defects, though this depends on the time during the pregnancy when the infection was acquired by the mother. Toxoplasmosis is acquired by ingesting the parasite when handling the stool of infected cats, drinking unpasteurized goat's milk, and, most commonly, by eating contaminated meat.

Rubella is the virus that causes German measles. If contracted early in the pregnancy, an infant may develop heart disease, retarded growth, hearing loss, blood disorders, vision problems, or pneumonia. Problems that may develop during childhood include central nervous system disease, immune disorders, or thyroid disease.

Cytomegalovirus (CMV) is another viral infection that a mother may have acquired. More than half of all American adults have been infected with CMV at some point in their life and, in most cases, it does not cause severe illness. However, it may pass to a baby during the birth process and can also infect newborns through breast milk. Infected infants may have severe problems, such as hearing loss, vision problems, mental retardation, pneumonia, and seizures.

Herpes simplex virus (HSV) is a common viral infection. The two most common infections with HSV are "cold sores" affecting the lips and genital herpes. Both of these infections can recur. HSV is most commonly acquired through oral or genital contact. Newborns who contract the virus usually do so during travel through the birth canal of a woman who has a genital infection with HSV. The virus may spread throughout the newborn's body, attacking vital organs. Treatment with specific antiviral medication should begin as soon as possible in the infected newborn. Even if treated, surviving babies may have permanent damage to their central nervous system.

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Toxoplasma Antibody IgG, Toxoplasma gondii, Toxoplasma gondii Antibodies, IgG

Toxoplasma Antibody (IgG)

Also known as: CMV Antibody IgG, CMV IgG Ab, Cytomegalovirus Antibody IgG

Cytomegalovirus

Also known as: Herpes Simplex Virus 12 IgG TypeSpecific Antibodies HerpeSelect

Hsv 1 IgG Type Specific

Herpes simplex virus testing is performed to identify an acute herpes infection or to detect herpes antibodies, an indication of a previous exposure to herpes. One of the most common viral infections, herpes simplex virus (HSV) exists as two main types, HSV-1 and HSV-2. Both types are contagious and periodically cause small fever blisters (vesicles) that break to form open lesions. HSV-1 primarily causes blisters or "cold sores" around the oral cavity and mouth, while HSV-2 usually causes lesions around the genital area; however, either one can affect the oral or genital area.

Hsv 2 IgG Type Specific

Herpes simplex virus testing is performed to identify an acute herpes infection or to detect herpes antibodies, an indication of a previous exposure to herpes. One of the most common viral infections, herpes simplex virus (HSV) exists as two main types, HSV-1 and HSV-2. Both types are contagious and periodically cause small fever blisters (vesicles) that break to form open lesions. HSV-1 primarily causes blisters or "cold sores" around the oral cavity and mouth, while HSV-2 usually causes lesions around the genital area; however, either one can affect the oral or genital area.

Rubella Antibody (IgG)

Also known as: CMV Antibody IgM, CMV IgM Ab, Cytomegalovirus Antibody IgM

Cytomegalovirus