T3 Reverse, LC/MS/MS Most Popular

The T3 Reverse, LC/MS/MS test contains 1 test with 1 biomarker.

The assay may be useful in the diagnosis of nonthyroidal illness (NTI). Patients with NTI have low T3 concentrations and increased concentrations of rT3. RT3 may be useful in neonates to distinguish euthyroid sick syndrome from central hypothyroidism.

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Reverse T3, Reverse Triiodothyronine, RT3, T3 Reverse RT3 LCMSMS, Triiodothyronine Reverse

T3 Reverse, LC/MS/MS

Reverse T3 produced in the thyroid comes from the conversion of the storage hormone T4. Your body, especially the liver, can constantly be converting T4 to RT3 as a way to get rid of any unneeded T4. In any given day approx. 40% of T4 goes to T3 and 20% of T4 goes to Reverse T3. However in any situation where your body needs to conserve energy and focus on something else, it will change the above percentages, changing the conversion of RT3 to 50% or more, and the T3 goes down, down. Examples are emotional, physical, or biological stress, such as being chronically or acutely sick (the flu, pneumonia, etc), after surgery, after a car accident or any acute injury, chronic stress causing high cortisol, being exposed to an extremely cold environment, diabetes, aging, or even being on drugs like beta blockers and amiodarone.